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Lista de obras de Claudio Arra

A mouse model demonstrates a multigenic origin of congenital hypothyroidism

scientific journal article

A mouse model for hereditary thyroid dysgenesis and cleft palate

scientific journal article

A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice

artículo científico publicado en 2016

A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration

artículo científico publicado en 2009

A urokinase receptor-derived peptide inhibiting VEGF-dependent directional migration and vascular sprouting

artículo científico publicado en 2013

Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in mice

artículo científico publicado en 2012

An overview of loco-regional treatments in patients and mouse models for hepatocellular carcinoma.

artículo científico publicado en 2015

Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking.

artículo científico publicado en 2016

Antitumor activity of PEGylated biodegradable nanoparticles for sustained release of docetaxel in triple-negative breast cancer

artículo científico publicado en 2014

B cells contribute to the antitumor activity of CpG-oligodeoxynucleotide in a mouse model of metastatic lung carcinoma.

artículo científico publicado en 2011

BAG3 controls angiogenesis through regulation of ERK phosphorylation.

artículo científico publicado en 2012

BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein

artículo científico publicado en 2011

BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

artículo científico publicado en 2015

Biodegradable core-shell nanoassemblies for the delivery of docetaxel and Zn(II)-phthalocyanine inspired by combination therapy for cancer

artículo científico publicado en 2013

Biodegradable nanoparticles bearing amine groups as a strategy to alter surface features, biological identity and accumulation in a lung metastasis model

artículo científico publicado en 2018

CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation

artículo científico publicado en 2014

CBX7 is a tumor suppressor in mice and humans

artículo científico publicado en 2012

CBX7 is a tumor suppressor in mice and humans

CRIPTO-1: a novel target for therapeutic intervention in human carcinoma

artículo científico publicado en 2004

CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.

artículo científico publicado en 2016

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy

artículo científico publicado en 2010

Cancer-associated CD43 glycoforms as target of immunotherapy.

artículo científico publicado en 2013

Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity.

artículo científico publicado en 2015

Characterization of HMGA1P6 transgenic mouse embryonic fibroblasts

scientific article published on 13 August 2020

Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo

artículo científico publicado en 2011

Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells.

artículo científico publicado en 2010

Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors.

artículo científico publicado en 2011

Core-shell biodegradable nanoassemblies for the passive targeting of docetaxel: features, antiproliferative activity and in vivo toxicity

artículo científico publicado en 2011

CpG-ODN increases the release of VEGF in a mouse model of lung carcinoma

artículo científico publicado en 2010

Cripto haploinsufficiency affects in vivo colon tumor development

artículo científico publicado en 2014

Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells

artículo científico publicado en 2004

Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer.

artículo científico publicado en 2013

Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis

artículo científico publicado en 2008

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge.

artículo científico

Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer

artículo científico publicado en 2019

Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats.

artículo científico publicado en 2008

Dissecting the role of curcumin in tumour growth and angiogenesis in mouse model of human breast cancer

artículo científico publicado en 2015

Dual Oncogenic/Anti-Oncogenic Role of PATZ1 in FRTL5 Rat Thyroid Cells Transformed by the Oncogene

article

Early identification of left ventricular dysfunction induced by trastuzumab

artículo científico publicado en 2011

Effects of a human compact anti-ErbB2 antibody on prostate cancer.

artículo científico publicado en 2012

Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.

artículo científico publicado en 2008

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene

artículo científico publicado en 2013

Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.

artículo científico publicado en 2013

Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.

artículo científico publicado en 2008

Exposure to 50 Hz electromagnetic field raises the levels of the anti-apoptotic protein BAG3 in melanoma cells

artículo científico publicado en 2011

Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice

retracted article

Gastrin and cholecystokinin peptide-based radiopharmaceuticals: an in vivo and in vitro comparison.

artículo científico publicado en 2011

HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs

artículo científico publicado en 2014

HMGA1-pseudogenes and cancer

artículo científico publicado en 2016

HMGA2 cooperates with either p27(kip1) deficiency or Cdk4(R24C) mutation in pituitary tumorigenesis.

artículo científico publicado en 2017

HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

artículo científico publicado en 2006

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice

artículo científico publicado en 2006

Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype

artículo científico publicado en 2014

IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.

artículo científico publicado en 2010

Ibuprofen delivered by poly(lactic-co-glycolic acid) (PLGA) nanoparticles to human gastric cancer cells exerts antiproliferative activity at very low concentrations

artículo científico publicado en 2012

Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation

artículo científico publicado en 2004

Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum.

artículo científico publicado en 2015

Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice

artículo científico publicado en 2015

Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice

artículo científico publicado en 2009

In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging.

artículo científico publicado en 2004

In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging

artículo científico publicado en 2004

In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with 99mTc-tricarbonyl

artículo científico publicado en 2008

In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder.

artículo científico publicado en 2010

Inhibition of stromal CXCR4 impairs development of lung metastases.

artículo científico publicado en 2012

Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

artículo científico publicado en 2007

Inhibitory effect of (-)-epigallocatechin-3-gallate and bleomycin on human pancreatic cancer MiaPaca-2 cell growth

artículo científico publicado en 2015

Interleukin 18: friend or foe in cancer

artículo científico

Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice

artículo científico publicado en 2013

Modulation of cell apoptosis by AIR

artículo científico publicado en 2007

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

artículo científico publicado en 1999

Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression

artículo científico publicado en 2015

Mouse Models in Prostate Cancer Translational Research: From Xenograft to PDX

artículo científico publicado en 2016

NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma model.

artículo científico publicado en 2011

New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities.

artículo científico publicado en 2016

Novel metronomic chemotherapy and cancer vaccine combinatorial strategy for hepatocellular carcinoma in a mouse model

artículo científico publicado en 2015

PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration

artículo científico publicado en 2015

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas

artículo científico publicado en 2016

PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells

artículo científico publicado en 2016

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation

scientific article published in 2014

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

artículo científico publicado en 2012

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.

scientific article published on 24 October 2013

Peptide modified nanocarriers for selective targeting of bombesin receptors.

artículo científico publicado en 2010

Peptide-containing aggregates as selective nanocarriers for therapeutics.

artículo científico publicado en 2008

Plasmacytoid Dendritic Cells Alter the Antitumor Activity of CpG-Oligodeoxynucleotides in a Mouse Model of Lung Carcinoma

scientific article published on 20 September 2010

Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice

artículo científico publicado en 2013

Plasmacytoids dendritic cells are a therapeutic target in anticancer immunity.

artículo científico publicado en 2012

Polycomb protein family member CBX7 plays a critical role in cancer progression

artículo científico publicado en 2015

Polyinosinic-polycytidylic acid limits tumor outgrowth in a mouse model of metastatic lung cancer.

artículo científico publicado en 2012

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

artículo científico publicado en 2013

Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

artículo científico publicado en 2014

Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.

artículo científico publicado en 2014

Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples high-excitability rats.

artículo científico publicado en 2010

Prostate cancer detection in the "grey area" of prostate-specific antigen below 10 ng/ml: head-to-head comparison of the updated PCPT calculator and Chun's nomogram, two risk estimators incorporating prostate cancer antigen 3.

artículo científico publicado en 2010

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.

artículo científico publicado en 2014

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system

artículo científico publicado en 1995

Retraction notice to “Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice” [Eur J Cancer 47 (2011) 470–478]

article

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

artículo científico publicado en 2010

Rhes is involved in striatal function

scientific journal article

Role of BAG3 protein in leukemia cell survival and response to therapy.

artículo científico publicado en 2012

Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells

artículo científico publicado en 2010

SOM230, A New Somatostatin Analogue, Is Highly Effective in the Therapy of Growth Hormone/Prolactin-Secreting Pituitary Adenomas

scientific article published on 01 May 2007

Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts.

artículo científico publicado en 2000

Single amino acid substitutions in the chemotactic sequence of urokinase receptor modulate cell migration and invasion

artículo científico publicado en 2012

Strain Analysis in the Assessment of a Mouse Model of Cardiotoxicity due to Chemotherapy: Sample for Preclinical Research.

artículo científico publicado en 2016

Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis.

artículo científico publicado en 2009

Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo

artículo científico publicado en 2006

Target-based agents in neoadjuvant treatment of liver metastases from colorectal cancer: secret weapons in anti-cancer war?

artículo científico publicado en 2009

Targeting androgen receptor/Src complex impairs the aggressive phenotype of human fibrosarcoma cells

artículo científico publicado en 2013

The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitro and in vivo studies

artículo científico publicado en 2007

The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth

artículo científico publicado en 2014

The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.

artículo científico publicado en 2006

The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias.

artículo científico publicado en 2014

The emerging issue of cardiac dysfunction induced by antineoplastic angiogenesis inhibitors

artículo científico publicado el 16 de enero de 2013

The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways

artículo científico publicado en 2007

The role of morphine in animal models of human cancer: does morphine promote or inhibit the tumor growth?

artículo científico publicado en 2013

The soluble form of urokinase receptor promotes angiogenesis through its Ser⁸⁸-Arg-Ser-Arg-Tyr⁹² chemotactic sequence

scientific article published on 01 December 2010

The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

artículo científico publicado en 2015

The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells.

artículo científico publicado en 2016

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas

artículo científico publicado en 2005

Transient exposure to cytarabine increases peptide growth factor receptor expression and tumorigenicity of melanoma cells

artículo científico publicado en 1997

Triple negative breast cancer: looking for the missing link between biology and treatments

artículo científico publicado en 2015

Tumour biomarkers: homeostasis as a novel prognostic indicator

artículo científico publicado en 2016

Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): at the cross-road of pancreatic cancer cell proliferation

artículo científico publicado en 2013

Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence.

artículo científico publicado en 2014

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.

artículo científico publicado en 2010

β-hairpin peptide that targets vascular endothelial growth factor (VEGF) receptors: design, NMR characterization, and biological activity

artículo científico publicado en 2011