Lista de obras - Nobuyuki Takahashi - Dominio Público Uruguay

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.

artículo científico publicado en 2015

A combination of soy isoflavones and cello-oligosaccharides changes equol/O-desmethylangolensin production ratio and attenuates bone fragility in ovariectomized mice

artículo científico publicado en 2016

Abietic acid activates peroxisome proliferator-activated receptor-gamma (PPARgamma) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism.

artículo científico publicado en 2003

Activation of TRPV2 negatively regulates the differentiation of mouse brown adipocytes.

artículo científico publicado en 2016

Activation of maxi-anion channel by protein tyrosine dephosphorylation

artículo científico publicado en 2009

Activation of peroxisome proliferator-activated receptor-α (PPARα) in proximal intestine improves postprandial lipidemia in obese diabetic KK-Ay mice

artículo científico publicado en 2013

Activation of peroxisome proliferator-activated receptor-α (PPARα) suppresses postprandial lipidemia through fatty acid oxidation in enterocytes

artículo científico publicado en 2011

Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes.

artículo científico publicado en 2011

An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice

artículo científico publicado en 2015

Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes

artículo científico publicado en 2004

Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice

artículo científico publicado en 2011

Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation.

artículo científico publicado en 2013

Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes.

artículo científico publicado en 2008

Bixin activates PPARα and improves obesity-induced abnormalities of carbohydrate and lipid metabolism in mice

artículo científico publicado en 2012

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.

artículo científico publicado en 2009

Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

artículo científico publicado en 2011

Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPARalpha, promotes energy consumption and reduces visceral fat deposition in rats

scientific article published on 23 March 2006

Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism.

artículo científico publicado en 2004

Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes.

artículo científico publicado en 2005

ClC-3-independent sensitivity of apoptosis to Cl- channel blockers in mouse cardiomyocytes

artículo científico publicado en 2005

DHA attenuates postprandial hyperlipidemia via activating PPARα in intestinal epithelial cells.

scientific article published on 16 October 2013

Dehydroabietic acid activates peroxisome proliferator-activated receptor-γ and stimulates insulin-dependent glucose uptake into 3T3-L1 adipocytes.

artículo científico publicado en 2011

Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK-Ay mice.

artículo científico publicado en 2009

Development of a novel PPARγ ligand screening system using pinpoint fluorescence-probed protein

artículo científico publicado en 2011

Dietary factors evoke thermogenesis in adipose tissues

artículo científico

Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice.

artículo científico publicado en 2013

Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages

artículo científico publicado en 2010

Diosgenin, the main aglycon of fenugreek, inhibits LXRα activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice.

artículo científico publicado en 2010

Double dioxygenation by mouse 8S-lipoxygenase: specific formation of a potent peroxisome proliferator-activated receptor alpha agonist

artículo científico publicado en 2005

Dysfunction of regulatory volume increase is a key component of apoptosis

artículo científico publicado en 2006

Evaluation of canine T-cell dependent antibody response to the primary and secondary immunization with keyhole limpet hemocyanin.

artículo científico publicado en 2013

Expression of novel isoforms of the CIC-1 chloride channel in astrocytic glial cells in vitro

artículo científico publicado en 2004

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

artículo científico publicado en 1998

Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.

artículo científico publicado en 2011

Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.

artículo científico publicado en 2011

Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system.

artículo científico publicado en 2015

Food Components Modulate Obesity and Energy Metabolism via the Transcriptional Regulation of Lipid-Sensing Nuclear Receptors.

artículo científico publicado en 2015

Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies.

artículo científico publicado en 2010

Genome science of lipid metabolism and obesity.

artículo científico publicado en 2009

Geranylgeranyl pyrophosphate performs as an endogenous regulator of adipocyte function via suppressing the LXR pathway

artículo científico publicado en 2016

Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes.

artículo científico publicado en 2015

Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.

artículo científico publicado en 2013

Inhibitory effect of monoacylglycerol on fatty acid uptake into rat intestinal epithelial cells

artículo científico publicado en 2001

Involvement of mast cells in adipose tissue fibrosis

artículo científico publicado en 2013

Ischemia-induced enhancement of CFTR expression on the plasma membrane in neonatal rat ventricular myocytes

scientific journal article

Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue

artículo científico publicado en 2016

Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition

artículo científico publicado en 2012

Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation.

artículo científico publicado en 2009

Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice.

artículo científico publicado en 2016

Natural compounds regulate energy metabolism by the modulating the activity of lipid-sensing nuclear receptors.

artículo científico publicado en 2012

Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma

artículo científico publicado en 2002

Oxytocin receptor-deficient mice developed late-onset obesity

artículo científico publicado en 2008

Phenolic compounds from leaves of Casimiroa edulis showed adipogenesis activity.

artículo científico publicado en 2014

Physiological and pharmacological function of PPARs

artículo científico publicado en 2001

Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.

artículo científico publicado en 2005

Plasma metabolites of dietary flavonoids after combination meal consumption with onion and tofu in humans.

artículo científico publicado en 2013

Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells.

artículo científico publicado en 2000

Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreases plasma and hepatic triglyceride in obese diabetic mice

artículo científico publicado en 2012

Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes.

artículo científico publicado en 2015

Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo.

artículo científico publicado en 2010

Recognition system for dietary fatty acids in the rat small intestine

scientific article published on 01 August 1995

Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.

artículo científico publicado en 2005

Signalling events employed in the hypertonic activation of cation channels in HeLa cells

scientific article published on 01 January 2007

Soymorphin-5, a soy-derived μ-opioid peptide, decreases glucose and triglyceride levels through activating adiponectin and PPARα systems in diabetic KKAy mice.

artículo científico publicado en 2011

Sulforaphane inhibits osteoclast differentiation by suppressing the cell-cell fusion molecules DC-STAMP and OC-STAMP.

artículo científico publicado en 2016

Sulforaphene attenuates multinucleation of pre-osteoclasts by suppressing expression of cell-cell fusion-associated genes DC-STAMP, OC-STAMP, and Atp6v0d2.

artículo científico publicado en 2017

Taurine improves obesity-induced inflammatory responses and modulates the unbalanced phenotype of adipose tissue macrophages.

artículo científico publicado en 2013

Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice.

artículo científico publicado en 2011

Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes

artículo científico publicado en 2011

Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism.

artículo científico publicado en 2010

Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death.

artículo científico publicado en 2006

Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice.

artículo científico publicado en 2010

Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes

γ-Mangostin from Garcinia mangostana pericarps as a dual agonist that activates Both PPARα and PPARδ.

artículo científico publicado en 2013

Lista de obras de Nobuyuki Takahashi

10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.

A combination of soy isoflavones and cello-oligosaccharides changes equol/O-desmethylangolensin production ratio and attenuates bone fragility in ovariectomized mice

Abietic acid activates peroxisome proliferator-activated receptor-gamma (PPARgamma) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism.

Activation of TRPV2 negatively regulates the differentiation of mouse brown adipocytes.

Activation of maxi-anion channel by protein tyrosine dephosphorylation

Activation of peroxisome proliferator-activated receptor-α (PPARα) in proximal intestine improves postprandial lipidemia in obese diabetic KK-Ay mice

Activation of peroxisome proliferator-activated receptor-α (PPARα) suppresses postprandial lipidemia through fatty acid oxidation in enterocytes

Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes.

An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice

Anthocyanin enhances adipocytokine secretion and adipocyte-specific gene expression in isolated rat adipocytes

Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice

Auraptene suppresses inflammatory responses in activated RAW264 macrophages by inhibiting p38 mitogen-activated protein kinase activation.

Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes.

Bixin activates PPARα and improves obesity-induced abnormalities of carbohydrate and lipid metabolism in mice

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.

Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPARalpha, promotes energy consumption and reduces visceral fat deposition in rats

Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism.

Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes.

ClC-3-independent sensitivity of apoptosis to Cl- channel blockers in mouse cardiomyocytes

DHA attenuates postprandial hyperlipidemia via activating PPARα in intestinal epithelial cells.

Dehydroabietic acid activates peroxisome proliferator-activated receptor-γ and stimulates insulin-dependent glucose uptake into 3T3-L1 adipocytes.

Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK-Ay mice.

Development of a novel PPARγ ligand screening system using pinpoint fluorescence-probed protein

Dietary factors evoke thermogenesis in adipose tissues

Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice.

Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages

Diosgenin, the main aglycon of fenugreek, inhibits LXRα activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice.

Double dioxygenation by mouse 8S-lipoxygenase: specific formation of a potent peroxisome proliferator-activated receptor alpha agonist

Dysfunction of regulatory volume increase is a key component of apoptosis

Evaluation of canine T-cell dependent antibody response to the primary and secondary immunization with keyhole limpet hemocyanin.

Expression of novel isoforms of the CIC-1 chloride channel in astrocytic glial cells in vitro

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.

Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.

Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system.

Food Components Modulate Obesity and Energy Metabolism via the Transcriptional Regulation of Lipid-Sensing Nuclear Receptors.

Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies.

Genome science of lipid metabolism and obesity.

Geranylgeranyl pyrophosphate performs as an endogenous regulator of adipocyte function via suppressing the LXR pathway

Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes.

Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.

Inhibitory effect of monoacylglycerol on fatty acid uptake into rat intestinal epithelial cells

Involvement of mast cells in adipose tissue fibrosis

Ischemia-induced enhancement of CFTR expression on the plasma membrane in neonatal rat ventricular myocytes

Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue

Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition

Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation.

Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice.

Natural compounds regulate energy metabolism by the modulating the activity of lipid-sensing nuclear receptors.

Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma

Oxytocin receptor-deficient mice developed late-onset obesity

Phenolic compounds from leaves of Casimiroa edulis showed adipogenesis activity.

Physiological and pharmacological function of PPARs

Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.

Plasma metabolites of dietary flavonoids after combination meal consumption with onion and tofu in humans.

Posttranscriptional regulation of alpha-catenin expression is required for Wnt signaling in L cells.

Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreases plasma and hepatic triglyceride in obese diabetic mice

Proinflammatory cytokine interleukin-1β suppresses cold-induced thermogenesis in adipocytes.

Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo.

Recognition system for dietary fatty acids in the rat small intestine

Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line.

Signalling events employed in the hypertonic activation of cation channels in HeLa cells

Soymorphin-5, a soy-derived μ-opioid peptide, decreases glucose and triglyceride levels through activating adiponectin and PPARα systems in diabetic KKAy mice.

Sulforaphane inhibits osteoclast differentiation by suppressing the cell-cell fusion molecules DC-STAMP and OC-STAMP.

Sulforaphene attenuates multinucleation of pre-osteoclasts by suppressing expression of cell-cell fusion-associated genes DC-STAMP, OC-STAMP, and Atp6v0d2.

Taurine improves obesity-induced inflammatory responses and modulates the unbalanced phenotype of adipose tissue macrophages.

Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice.

Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes

Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism.

Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death.

Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice.

Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes

γ-Mangostin from Garcinia mangostana pericarps as a dual agonist that activates Both PPARα and PPARδ.