Lista de obras - Eric Defrancq - Dominio Público Uruguay

A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: a biomolecular tool that behaves as a "seppuku molecule".

artículo científico publicado en 2009

A rigid dinuclear ruthenium(II) complex as an efficient photoactive agent for bridging two guanine bases of a duplex or quadruplex oligonucleotide.

artículo científico publicado en 2010

Access to a stabilized i-motif DNA structure through four successive ligation reactions on a cyclopeptide scaffold

artículo científico publicado en 2020

Adduct formation by photo-induced electron transfer between photo-oxidising Ru(II) complexes and tryptophan.

artículo científico publicado en 2004

An oxime-based glycocluster microarray.

artículo científico publicado en 2017

Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides

artículo científico publicado en 2014

Characterization of a modified gold platform for the development of a label-free anti-thrombin aptasensor

artículo científico publicado en 2012

Chemoselective oxime and thiazolidine bond formation: a versatile and efficient route to the preparation of 3'-peptide-oligonucleotide conjugates

artículo científico publicado en 2004

Chemoselectively addressable template: a valuable tool for the engineering of molecular conjugates

artículo científico publicado en 2006

Click–click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures ⬇️

artículo científico publicado el 10 de mayo de 2012

Closer to nature: an ATP-driven bioinspired catalytic oxidation process

artículo científico publicado en 2013

Cobalt(III)porphyrin to target G-quadruplex DNA.

artículo científico publicado en 2015

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

artículo científico publicado en 2021

Construction of anti-parallel G-quadruplexes through sequential templated click

scientific article published on 01 March 2015

Design and synthesis of novel hybrid metal complex-DNA conjugates: key building blocks for multimetallic linear DNA nanoarrays.

artículo científico publicado en 2009

Detection of secondary structures in 17-mer Ru(II)-labeled single-stranded oligonucleotides from luminescence lifetime studies

artículo científico publicado en 2005

Determination of DNA guanine sites forming photo-adducts with Ru(II)-labeled oligonucleotides; DNA polymerase inhibition by the resulting photo-crosslinking

artículo científico publicado en 2003

Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry

artículo científico publicado en 2020

Efficient Inhibition of Telomerase by Nickel-Salophen Complexes.

artículo científico publicado en 2016

Efficient conjugation and characterization of distamycin-based peptides with selected oligonucleotide stretches.

artículo científico publicado en 2004

Efficient conjugation of oligonucleotides through aromatic oxime formation.

artículo científico publicado en 2009

Efficient surface patterning of oligonucleotides inside a glass capillary through oxime bond formation.

artículo científico publicado en 2007

Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: application to the determination of thrombin and anti-cholera toxin antibody.

artículo científico publicado en 2012

Evaluation of a new biocompatible poly(N-(morpholino ethyl methacrylate)-based copolymer for the delivery of ruthenium oligonucleotides, targeting HPV16 E6 oncogene

artículo científico publicado en 2013

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.

artículo científico publicado en 2012

Head-to-Tail Oxime Cyclization of Oligodeoxynucleotides for the Efficient Synthesis of Circular DNA Analogues ⬇️

artículo científico publicado el 31 de octubre de 2003

Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity - The Importance of Cellular Distribution

Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film.

artículo científico publicado en 2016

Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation

artículo científico publicado en 2003

Highly efficient synthesis of peptide-oligonucleotide conjugates: chemoselective oxime and thiazolidine formation

artículo científico publicado en 2001

Improvement of porphyrins for G-quadruplex DNA targeting

artículo científico publicado en 2011

Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film

artículo científico publicado en 2010

Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film ⬇️

artículo científico publicado el 3 de agosto de 2012

Label-free photoelectrochemical detection of double-stranded HIV DNA by means of a metallointercalator-functionalized electrogenerated polymer

artículo científico publicado en 2014

Light-Triggered Green Fluorescent Protein Silencing in Human Keratinocytes in Culture Using Antisense Oligonucleotides Coupled to a Photoreactive Ruthenium(II) Complex

article

Macrocyclic host-dye reporter for sensitive sandwich-type fluorescent aptamer sensor

artículo científico publicado en 2015

Metal‐Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays ⬇️

artículo científico publicado el 15 de noviembre de 2010

Methods for investigating G-quadruplex DNA/ligand interactions.

artículo científico publicado en 2011

New Ruthenium-Based Probes for Selective G-Quadruplex Targeting.

artículo científico publicado en 2017

New method to prepare peptide-oligonucleotide conjugates through glyoxylic oxime formation.

artículo científico publicado en 2004

Oligonucleotide Functionalization of Hollow Triangular Gold Silver Alloy Nanoboxes

Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures

artículo científico publicado en 2010

Optical Properties andIn VitroBiological Studies of Oligonucleotide-Modified Quantum Dots

article published in 2013

Oxidizing Ru(II) complexes as irreversible and specific photo-cross-linking agents of oligonucleotide duplexes

artículo científico publicado en 2009

Palladium-Mediated Labeling of Nucleic Acids.

artículo científico publicado en 2016

Parameters influencing the photo-induced electron transfer from tryptophan-containing peptides to a Ru(II) complex: a systematic study.

artículo científico publicado en 2015

Phosphorylating Reagent-Free Synthesis of 5′-Phosphate Oligonucleotides by Controlled Oxidative Degradation of Their 5′-End ⬇️

artículo científico publicado el 5 de abril de 2012

Photo-cross-linking between polymers derivatized with photoreactive ruthenium-1,4,5,8-tetraazaphenanthrene complexes and guanine-containing oligonucleotides

artículo científico publicado en 2007

Photo-reactive Ru(II)-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes.

artículo científico publicado en 2010

Photoadduct leading to crosslinking in Ru(II)-derivatized oligonucleotides.

artículo científico publicado en 2003

Photocrosslinking between peptide-peptide or peptide-oligonucleotide by Ru(II)-TAP complexes.

artículo científico publicado en 2011

Photocrosslinking in ruthenium-labelled duplex oligonucleotides.

artículo científico publicado en 2003

Photoinduced electron transfer from tryptophan to Ru(II)TAP complexes: the primary process for photo-cross-linking with oligopeptides.

artículo científico publicado en 2010

Photoreaction of [Ru(hat)2phen]2+ with guanosine-5'-monophosphate and DNA: formation of new types of photoadducts

artículo científico publicado en 2005

Plasmon-induced CD response of oligonucleotide-conjugated metal nanoparticles

Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites

artículo científico publicado en 2020

Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.

artículo científico publicado en 2015

Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent

scientific article published on 24 January 2020

Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.

artículo científico publicado en 2012

Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands

artículo científico publicado en 2019

Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes.

artículo científico publicado en 2015

Specificity of Light-Induced Covalent Adduct Formation between RuIIOligonucleotide Conjugates and Target Sequences for Gene Silencing Applications

article

Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes.

artículo científico publicado en 2008

Surface plasmon resonance study of the interaction of N-methyl mesoporphyrin IX with G-quadruplex DNA

scientific article published on 01 February 2020

Surface-immobilized DNAzyme-type biocatalysis

artículo científico publicado en 2014

Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels.

artículo científico publicado en 2012

Synthesis and photophysical studies of a multivalent photoreactive Ru-calix[4]arene complex bearing RGD-containing cyclopentapeptides

article

Targeting G-Rich DNA Structures with Photoreactive Bis-Cyclometallated Iridium(III) Complexes

artículo científico publicado en 2019

Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.

artículo científico

Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands

artículo científico

The 7-nitroindole nucleoside as a photochemical precursor of 2'-deoxyribonolactone: access to DNA fragments containing this oxidative abasic lesion

artículo científico publicado en 2000

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

artículo científico publicado en 2015

The oxime bond formation as an efficient chemical tool for the preparation of 3',5'-bifunctionalised oligodeoxyribonucleotides.

artículo científico publicado en 2004

The pKa value of the proximal water molecule trans to a high-valent MnV[double bond, length as m-dash]O porphyrin: towards the control of reactivity by pH.

artículo científico publicado en 2017

Towards the Development of Photo-Reactive Ruthenium (II) Complexes Targeting Telomeric G-Quadruplex DNA

Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY.

artículo científico publicado en 2013

Use of an aminooxy linker for the functionalization of oligodeoxyribonucleotides

artículo científico publicado en 2001

Use of gamma-aminopropyl-coated glass surface for the patterning of oligonucleotides through oxime bond formation

artículo científico publicado en 2008

Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction ⬇️

artículo científico publicado el 29 de septiembre de 2011

Lista de obras de Eric Defrancq

A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: a biomolecular tool that behaves as a "seppuku molecule".

A rigid dinuclear ruthenium(II) complex as an efficient photoactive agent for bridging two guanine bases of a duplex or quadruplex oligonucleotide.

Access to a stabilized i-motif DNA structure through four successive ligation reactions on a cyclopeptide scaffold

Adduct formation by photo-induced electron transfer between photo-oxidising Ru(II) complexes and tryptophan.

An oxime-based glycocluster microarray.

Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides

Characterization of a modified gold platform for the development of a label-free anti-thrombin aptasensor

Chemoselective oxime and thiazolidine bond formation: a versatile and efficient route to the preparation of 3'-peptide-oligonucleotide conjugates

Chemoselectively addressable template: a valuable tool for the engineering of molecular conjugates

Click–click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures ⬇️

Closer to nature: an ATP-driven bioinspired catalytic oxidation process

Cobalt(III)porphyrin to target G-quadruplex DNA.

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

Construction of anti-parallel G-quadruplexes through sequential templated click

Design and synthesis of novel hybrid metal complex-DNA conjugates: key building blocks for multimetallic linear DNA nanoarrays.

Detection of secondary structures in 17-mer Ru(II)-labeled single-stranded oligonucleotides from luminescence lifetime studies

Determination of DNA guanine sites forming photo-adducts with Ru(II)-labeled oligonucleotides; DNA polymerase inhibition by the resulting photo-crosslinking

Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry

Efficient Inhibition of Telomerase by Nickel-Salophen Complexes.

Efficient conjugation and characterization of distamycin-based peptides with selected oligonucleotide stretches.

Efficient conjugation of oligonucleotides through aromatic oxime formation.

Efficient surface patterning of oligonucleotides inside a glass capillary through oxime bond formation.

Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: application to the determination of thrombin and anti-cholera toxin antibody.

Evaluation of a new biocompatible poly(N-(morpholino ethyl methacrylate)-based copolymer for the delivery of ruthenium oligonucleotides, targeting HPV16 E6 oncogene

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.

Head-to-Tail Oxime Cyclization of Oligodeoxynucleotides for the Efficient Synthesis of Circular DNA Analogues ⬇️

Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity - The Importance of Cellular Distribution

Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film.

Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation

Highly efficient synthesis of peptide-oligonucleotide conjugates: chemoselective oxime and thiazolidine formation

Improvement of porphyrins for G-quadruplex DNA targeting

Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film

Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film ⬇️

Label-free photoelectrochemical detection of double-stranded HIV DNA by means of a metallointercalator-functionalized electrogenerated polymer

Light-Triggered Green Fluorescent Protein Silencing in Human Keratinocytes in Culture Using Antisense Oligonucleotides Coupled to a Photoreactive Ruthenium(II) Complex

Macrocyclic host-dye reporter for sensitive sandwich-type fluorescent aptamer sensor

Metal‐Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays ⬇️

Methods for investigating G-quadruplex DNA/ligand interactions.

New Ruthenium-Based Probes for Selective G-Quadruplex Targeting.

New method to prepare peptide-oligonucleotide conjugates through glyoxylic oxime formation.

Oligonucleotide Functionalization of Hollow Triangular Gold Silver Alloy Nanoboxes

Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures

Optical Properties andIn VitroBiological Studies of Oligonucleotide-Modified Quantum Dots

Oxidizing Ru(II) complexes as irreversible and specific photo-cross-linking agents of oligonucleotide duplexes

Palladium-Mediated Labeling of Nucleic Acids.

Parameters influencing the photo-induced electron transfer from tryptophan-containing peptides to a Ru(II) complex: a systematic study.

Phosphorylating Reagent-Free Synthesis of 5′-Phosphate Oligonucleotides by Controlled Oxidative Degradation of Their 5′-End ⬇️

Photo-cross-linking between polymers derivatized with photoreactive ruthenium-1,4,5,8-tetraazaphenanthrene complexes and guanine-containing oligonucleotides

Photo-reactive Ru(II)-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes.

Photoadduct leading to crosslinking in Ru(II)-derivatized oligonucleotides.

Photocrosslinking between peptide-peptide or peptide-oligonucleotide by Ru(II)-TAP complexes.

Photocrosslinking in ruthenium-labelled duplex oligonucleotides.

Photoinduced electron transfer from tryptophan to Ru(II)TAP complexes: the primary process for photo-cross-linking with oligopeptides.

Photoreaction of [Ru(hat)2phen]2+ with guanosine-5'-monophosphate and DNA: formation of new types of photoadducts

Plasmon-induced CD response of oligonucleotide-conjugated metal nanoparticles

Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites

Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.

Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent

Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.

Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands

Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes.

Specificity of Light-Induced Covalent Adduct Formation between RuIIOligonucleotide Conjugates and Target Sequences for Gene Silencing Applications

Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes.

Surface plasmon resonance study of the interaction of N-methyl mesoporphyrin IX with G-quadruplex DNA

Surface-immobilized DNAzyme-type biocatalysis

Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels.

Synthesis and photophysical studies of a multivalent photoreactive Ru-calix[4]arene complex bearing RGD-containing cyclopentapeptides

Targeting G-Rich DNA Structures with Photoreactive Bis-Cyclometallated Iridium(III) Complexes

Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.

Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands

The 7-nitroindole nucleoside as a photochemical precursor of 2'-deoxyribonolactone: access to DNA fragments containing this oxidative abasic lesion

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

The oxime bond formation as an efficient chemical tool for the preparation of 3',5'-bifunctionalised oligodeoxyribonucleotides.

The pKa value of the proximal water molecule trans to a high-valent MnV[double bond, length as m-dash]O porphyrin: towards the control of reactivity by pH.

Towards the Development of Photo-Reactive Ruthenium (II) Complexes Targeting Telomeric G-Quadruplex DNA

Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY.

Use of an aminooxy linker for the functionalization of oligodeoxyribonucleotides

Use of gamma-aminopropyl-coated glass surface for the patterning of oligonucleotides through oxime bond formation

Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction ⬇️