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Lista de obras de Nicole Borth

5.2 Functional -Omics for Cell Lines and Processes: The -Omics Technologies on the Example of CHO Cells

A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

artículo científico publicado en 2016

A Dual-Enzyme Hydrogen Peroxide Generation Machinery in Hydrogels Supports Antimicrobial Wound Treatment.

artículo científico publicado en 2017

A continuous multistage roller reactor for animal cell culture: 1. Patterns of growth, production and catabolism of a murine hybridoma

artículo científico publicado en 1990

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets.

artículo científico publicado en 2019

A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells

artículo científico publicado en 2012

A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines

artículo científico publicado en 2016

A study on the temperature dependency and time course of the cold capture antibody secretion assay

artículo científico publicado en 2009

Analysis of changes during subclone development and ageing of human antibody-producing heterohybridoma cells by northern blot and flow cytometry.

artículo científico publicado en 1999

Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation

artículo científico publicado en 2014

Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data

artículo científico publicado en 2015

Applications of cell sorting in biotechnology

artículo científico publicado en 2006

Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry

artículo científico publicado en 2003

Baculovirus surface display: Construction and screening of a eukaryotic epitope library ⬇️

artículo científico publicado el 1 de abril de 1998

CHO microRNA engineering is growing up: recent successes and future challenges

artículo científico publicado en 2013

CHO-K1 host cells adapted to growth in glutamine-free medium by FACS-assisted evolution

artículo científico publicado en 2010

CHOmine: an integrated data warehouse for CHO systems biology and modeling.

artículo científico publicado en 2017

Changes during subclone development and ageing of human antibody-producing recombinant CHO cells

artículo científico publicado en 1999

Characterization of a novel cell penetrating peptide derived from human Oct4.

artículo científico publicado en 2014

Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells.

artículo científico publicado en 2016

Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org

artículo científico publicado en 2011

Chinese hamster genome sequenced from sorted chromosomes

artículo científico publicado en 2013

Chitosan hydrogel formation using laccase activated phenolics as cross-linkers

artículo científico publicado en 2016

ChromaWizard: An open source image analysis software for multicolor fluorescence in situ hybridization analysis

artículo científico publicado en 2018

Comparison of the production of a human monoclonal antibody against HIV-1 by heterohybridoma cells and recombinant CHO cells: A flow cytometric study

artículo científico publicado en 1996

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.

artículo científico publicado en 2016

Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

artículo científico publicado en 2012

Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines

artículo científico publicado en 2014

Construction of a stability landscape of the CH3 domain of human IgG1 by combining directed evolution with high throughput sequencing

artículo científico publicado en 2012

Corrigendum to "Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells" [J. Biotechnol. 227 (2016) 120-130].

artículo científico publicado en 2016

Determination of division rates of rCHO cells in high density and immobilized fermentation systems by flow cytometry

artículo científico publicado en 1992

Determination of liposome size distribution by flow cytometry

artículo científico publicado en 2000

Dynamic mRNA and miRNA profiling of CHO-K1 suspension cell cultures

artículo científico publicado en 2011

Editorial: On the cusp of rational CHO cell engineering

artículo científico publicado en 2015

Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

artículo científico publicado en 2005

Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

artículo científico publicado en 2004

Efficient selection of high-producing subclones during gene amplification of recombinant Chinese hamster ovary cells by flow cytometry and cell sorting

artículo científico publicado en 2000

Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cells

artículo científico publicado en 2014

Enhanced Genome Editing Tools For Multi-Gene Deletion Knock-Out Approaches Using Paired CRISPR sgRNAs in CHO Cells

artículo científico publicado en 2017

Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture

article

Error propagation in constraint-based modeling of Chinese hamster ovary cells

scientific article published on 19 December 2020

Establishment of a strategy for the rapid generation of a monoclonal antibody against the human protein SNEV (hNMP200) by flow-cytometric cell sorting

artículo científico publicado en 2005

Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing

artículo científico publicado en 2011

Flow Cytometric Analysis of Metabolic Stress Effects Due to Recombinant Plasmids and Proteins in Escherichia coli Production Strains

article

Flow cytometric analysis of bacterial physiology during induction of foreign protein synthesis in recombinant Escherichia coli cells

artículo científico publicado en 1998

Flow cytometry and two-dimensional electrophoresis (2-DE) for system evaluation of long term continuous perfused animal cell cultures in macroporous beads

article

Flow-cytometry and cell sorting: an efficient approach to investigate productivity and cell physiology in mammalian cell factories

artículo científico publicado en 2012

Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms

scientific article published on 21 July 2019

Genetically different wine yeasts isolated from Austrian vine-growing regions influence wine aroma differently and contain putative hybrids betweenSaccharomyces cerevisiaeandSaccharomyces kudriavzevii

artículo científico publicado en 2007

Growth and production kinetics of human x mouse and mouse hybridoma cells at reduced temperature and serum content

artículo científico publicado en 1992

Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth

artículo científico publicado en 2011

High-throughput screening and selection of mammalian cells for enhanced protein production

artículo científico publicado en 2016

Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

artículo científico publicado en 2014

Immunoglobulin G specifically binding plant N-glycans with high affinity could be generated in rabbits but not in mice

artículo científico publicado en 2005

Improvement of lactic acid production in Saccharomyces cerevisiae by cell sorting for high intracellular pH.

artículo científico publicado en 2006

Improvement of the energy metabolism of recombinant CHO cells by cell sorting for reduced mitochondrial membrane potential

artículo científico publicado en 2007

Intracellular pH distribution in Saccharomyces cerevisiae cell populations, analyzed by flow cytometry

artículo científico publicado en 2005

Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

artículo científico publicado en 2016

Long-Term Stability Of Continuously Perfused Animal Cells Immobilized On Novel Macroporous Microcarriers

Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity

artículo científico publicado en 2015

Modulation of neural carbohydrate epitope expression in Drosophila melanogaster cells

artículo científico publicado en 2005

Next-generation sequencing of the CHO cell transcriptome

artículo científico publicado en 2011

Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

artículo científico publicado en 2011

Nuclear flow FISH: isolation of cell nuclei improves the determination of telomere lengths

artículo científico publicado en 2005

Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon

artículo científico publicado en 2010

One plus one makes three: adding value by co-transfection of anti-apoptotic genes during transient gene expression

article

Optimization of recombinant protein expression level in Escherichia coli by flow cytometry and cell sorting

artículo científico publicado en 2002

Optimization of sorting conditions for the selection of stable, high-producing mammalian cell lines

artículo científico publicado en 1999

Prediction of transcribed PIWI-interacting RNAs from CHO RNAseq data

artículo científico publicado en 2013

Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors

artículo científico publicado en 2006

Process parameter shifting: Part II. Biphasic cultivation-A tool for enhancing the volumetric productivity of batch processes using Epo-Fc expressing CHO cells

artículo científico publicado en 2006

Quantification of human diamine oxidase.

artículo científico publicado en 2016

Random epigenetic modulation of CHO cells by repeated knock-down of DNA-methyltransferases increases population diversity and enables sorting of cells with higher production capacities

artículo científico publicado en 2020

Recombinant human diamine oxidase activity is not inhibited by ethanol, acetaldehyde, disulfiram, diethyldithiocarbamate or cyanamide

artículo científico publicado en 2016

Recon 2.2: from reconstruction to model of human metabolism ⬇️

artículo científico publicado en 2016

Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction

artículo científico publicado en 2014

Reducing Recon 2 for steady-state flux analysis of HEK cell culture

article

Rhodamine 123 fluorescence of immortal hybridoma cell lines as a function of glucose concentration

scientific article published on 01 January 1993

Screening for improved cell performance: selection of subclones with altered production kinetics or improved stability by cell sorting

artículo científico publicado en 2004

Selection of CHO host cell subclones with increased specific antibody production rates by repeated cycles of transient transfection and cell sorting

artículo científico publicado en 2011

Stable overexpression of miR-17 enhances recombinant protein production of CHO cells

artículo científico publicado en 2014

The CHO miRNA Transcriptome

Transcriptomic changes in CHO cells after adaptation to suspension growth in protein-free medium analysed by a species-specific microarray

artículo científico

Transfection of glycoprotein encoding mRNA for swift evaluation of N-glycan engineering strategies

artículo científico publicado en 2020

Transient manipulation of the expression level of selected growth rate correlating microRNAs does not increase growth rate in CHO-K1 cells

artículo científico publicado en 2019

Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells

artículo científico publicado en 2017

Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing

artículo científico publicado en 2011

Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics

artículo científico publicado en 2012

What can mathematical modelling say about CHO metabolism and protein glycosylation?

artículo científico publicado en 2017

miRNAs – pathway engineering of CHO cell factories that avoids translational burdening ⬇️

artículo científico publicado el 4 de junio de 2012

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