Lista de obras - Paul T. Elkington - Dominio Público Uruguay

A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis.

artículo científico publicado en 2017

Advanced cellular systems to study tuberculosis treatment

artículo científico publicado en 2018

Analysis of matrix metalloproteinase secretion by macrophages.

artículo científico publicado en 2009

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

artículo científico publicado en 2020

Anti-Tuberculosis Activity of Three Carbapenems, Clofazimine and Nitazoxanide Using a Novel Ex Vivo Phenotypic Drug Susceptibility Model of Human Tuberculosis

artículo científico publicado en 2022

Antimycobacterial drugs modulate immunopathogenic matrix metalloproteinases in a cellular model of pulmonary tuberculosis

artículo científico publicado en 2014

Bioelectrospray Methodology for Dissection of the Host-pathogen Interaction in Human Tuberculosis

artículo científico publicado en 2017

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.

artículo científico publicado en 2017

Calcineurin Inhibitors and Variation in the Performance of Interferon-Gamma Release Assays Used to Detect TB Infection

artículo científico publicado en 2019

Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis

artículo científico publicado en 2015

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

artículo científico publicado en 2016

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

artículo científico publicado en 2017

Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis

scientific article published on 11 August 2020

Controlled Generation of Microspheres Incorporating Extracellular Matrix Fibrils for Three-Dimensional Cell Culture

artículo científico publicado en 2014

Corticosteroids and infliximab impair the performance of interferon-γ release assays used for diagnosis of latent tuberculosis.

artículo científico publicado en 2017

Cytokine diagnosis of pleural TB: will it stand the test of time?

artículo científico publicado en 2017

Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

artículo científico publicado en 2017

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

scientific article published on 26 July 2016

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

artículo científico publicado en 2012

Early Secretory Antigenic Target-6 Drives Matrix Metalloproteinase-10 Gene Expression and Secretion in Tuberculosis

artículo científico publicado en 2016

Environmental temperature impacts on the performance of QuantiFERON-TB Gold In-Tube assays

artículo científico publicado en 2015

Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection.

artículo científico publicado en 2017

Ethnic variation in inflammatory profile in tuberculosis

artículo científico publicado en 2013

Extremes of age are associated with indeterminate QuantiFERON-TB gold assay results

artículo científico publicado en 2014

Filter sterilization of highly infectious samples to prevent false negative analysis of matrix metalloproteinase activity.

artículo científico publicado en 2005

Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis.

artículo científico publicado en 2015

Gene Expression Signatures in Tuberculosis Have Greater Overlap with Autoimmune Diseases Than with Infectious Diseases

artículo científico publicado en 2017

HIV-1 infection of macrophages dysregulates innate immune responses to Mycobacterium tuberculosis by inhibition of interleukin-10.

artículo científico publicado en 2013

Hypoxia and tissue destruction in pulmonary TB

artículo científico publicado en 2016

Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis

artículo científico publicado en 2018

IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis

artículo científico publicado en 2006

Implications of Tuberculosis Reactivation after Immune Checkpoint Inhibition

In Vitro Granuloma Models of Tuberculosis: Potential and Challenges

scientific article published on 01 May 2019

In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protein kinase-dependent pathway

artículo científico publicado en 2013

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis

artículo científico publicado en 2013

Induced sputum is safe and well-tolerated for TB diagnosis in a resource-poor primary healthcare setting

artículo científico publicado en 2014

Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets

artículo científico publicado en 2021

Interleukin-17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis.

artículo científico publicado en 2018

Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus-associated Tuberculosis

scientific article published on 01 April 2020

MMP-1 drives immunopathology in human tuberculosis and transgenic mice.

artículo científico publicado en 2011

MMP12, Lung Function, and COPD in High-Risk Populations

scientific article published on 01 April 2010

Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology

artículo científico publicado en 2019

Matrix Metalloproteinases in Pulmonary and Central Nervous System Tuberculosis—A Review ⬇️

artículo científico

Matrix metalloproteinase-1 is regulated in tuberculosis by a p38 MAPK-dependent, p-aminosalicylic acid-sensitive signaling cascade.

artículo científico publicado en 2009

Matrix metalloproteinases in tuberculosis.

artículo científico publicado en 2011

Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.

artículo científico publicado en 2015

Molecular Imaging in TB: From the Bench to the Clinic

scholarly article

Monocyte-Dependent Fibroblast CXCL8 Secretion Occurs in Tuberculosis and Limits Survival of Mycobacteria within Macrophages

artículo científico publicado en 2007

Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo.

artículo científico publicado en 2007

Monocyte-dependent oncostatin M and TNF-alpha synergize to stimulate unopposed matrix metalloproteinase-1/3 secretion from human lung fibroblasts in tuberculosis

artículo científico publicado en 2008

Monocytes infected with Mycobacterium tuberculosis regulate MAP kinase-dependent astrocyte MMP-9 secretion

artículo científico publicado en 2006

Multifocal cortical myoclonus and cerebral amyloid beta-peptide angiopathy

artículo científico publicado en 1998

Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation

artículo científico publicado en 2015

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology.

artículo científico publicado en 2017

Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch

artículo científico publicado en 2005

Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks

artículo científico publicado en 2010

Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1.

artículo científico publicado en 2005

Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways. ⬇️

artículo científico publicado en 2011

Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis

artículo científico publicado en 2015

Optimisation of bioluminescent reporters for use with mycobacteria

artículo científico publicado en 2010

Pathogenesis of ocular tuberculosis: New observations and future directions

artículo científico publicado en 2020

Permutations of time and place in tuberculosis

artículo científico publicado en 2015

Personal respirators for population level control of the COVID19 pandemic

scientific article published on 23 April 2020

Personal respirators for population level control of the COVID19 pandemic

scientific article published on 05 May 2020

Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis

artículo científico publicado en 2013

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection

artículo científico publicado en 2017

Reconsidering the Optimal Immune Response to Mycobacterium tuberculosis

scientific article published on 01 February 2020

Regulation of matrix metalloproteinase-1, -3, and -9 in Mycobacterium tuberculosis-dependent respiratory networks by the rapamycin-sensitive PI3K/p70(S6K) cascade.

artículo científico publicado en 2013

Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD.

artículo científico publicado en 2015

Repetitive Aerosol Exposure Promotes Cavitary Tuberculosis and Enables Screening for Targeted Inhibitors of Extensive Lung Destruction

scholarly article by Michael E Urbanowski et al published 5 June 2018 in Journal of Infectious Diseases

STAT3, p38 MAPK, and NF-kappaB drive unopposed monocyte-dependent fibroblast MMP-1 secretion in tuberculosis

artículo científico publicado en 2009

Seasonal variation in the performance of QuantiFERON-TB Gold In-Tube assays used for the diagnosis of tuberculosis infection.

artículo científico publicado en 2018

Spatz-Lindenberg disease: a rare cause of vascular dementia

artículo científico publicado en 1999

Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis

artículo científico publicado en 2015

Synergistic up-regulation of epithelial cell matrix metalloproteinase-9 secretion in tuberculosis.

artículo científico publicado en 2007

The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis.

artículo científico publicado en 2015

The effect of electromagnetic stimulation of the posterior parietal cortex on eye movements

artículo científico publicado en 1992

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

artículo científico

Towards host-directed therapies for tuberculosis

artículo científico publicado en 2015

Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test.

artículo científico publicado en 2011

Tuberculosis and TNF-inhibitors: history of exposure should outweigh investigations

artículo científico publicado en 2014

Tuberculosis associated with Triplet therapy for lung cancer

artículo científico publicado en 2020

Tuberculosis immunopathology: the neglected role of extracellular matrix destruction.

artículo científico publicado en 2011

Tuberculosis, pulmonary cavitation, and matrix metalloproteinases.

artículo científico publicado en 2014

Tuberculosis: An Infection-Initiated Autoimmune Disease?

artículo científico publicado en 2016

Tuberculosis: time for a new perspective?

artículo científico publicado en 2013

Update in Mycobacterium tuberculosis lung disease 2014.

artículo científico publicado en 2015

Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment

artículo científico publicado en 2012

Lista de obras de Paul T. Elkington

A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis.

Advanced cellular systems to study tuberculosis treatment

Analysis of matrix metalloproteinase secretion by macrophages.

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

Anti-Tuberculosis Activity of Three Carbapenems, Clofazimine and Nitazoxanide Using a Novel Ex Vivo Phenotypic Drug Susceptibility Model of Human Tuberculosis

Antimycobacterial drugs modulate immunopathogenic matrix metalloproteinases in a cellular model of pulmonary tuberculosis

Bioelectrospray Methodology for Dissection of the Host-pathogen Interaction in Human Tuberculosis

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.

Calcineurin Inhibitors and Variation in the Performance of Interferon-Gamma Release Assays Used to Detect TB Infection

Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

Comprehensive plasma proteomic profiling reveals biomarkers for active tuberculosis

Controlled Generation of Microspheres Incorporating Extracellular Matrix Fibrils for Three-Dimensional Cell Culture

Corticosteroids and infliximab impair the performance of interferon-γ release assays used for diagnosis of latent tuberculosis.

Cytokine diagnosis of pleural TB: will it stand the test of time?

Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

Early Secretory Antigenic Target-6 Drives Matrix Metalloproteinase-10 Gene Expression and Secretion in Tuberculosis

Environmental temperature impacts on the performance of QuantiFERON-TB Gold In-Tube assays

Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection.

Ethnic variation in inflammatory profile in tuberculosis

Extremes of age are associated with indeterminate QuantiFERON-TB gold assay results

Filter sterilization of highly infectious samples to prevent false negative analysis of matrix metalloproteinase activity.

Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis.

Gene Expression Signatures in Tuberculosis Have Greater Overlap with Autoimmune Diseases Than with Infectious Diseases

HIV-1 infection of macrophages dysregulates innate immune responses to Mycobacterium tuberculosis by inhibition of interleukin-10.

Hypoxia and tissue destruction in pulmonary TB

Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis

IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis

Implications of Tuberculosis Reactivation after Immune Checkpoint Inhibition

In Vitro Granuloma Models of Tuberculosis: Potential and Challenges

In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protein kinase-dependent pathway

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis

Induced sputum is safe and well-tolerated for TB diagnosis in a resource-poor primary healthcare setting

Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets

Interleukin-17 regulates matrix metalloproteinase activity in human pulmonary tuberculosis.

Invariant Natural Killer T-cell Dynamics in Human Immunodeficiency Virus-associated Tuberculosis

MMP-1 drives immunopathology in human tuberculosis and transgenic mice.

MMP12, Lung Function, and COPD in High-Risk Populations

Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology

Matrix Metalloproteinases in Pulmonary and Central Nervous System Tuberculosis—A Review ⬇️

Matrix metalloproteinase-1 is regulated in tuberculosis by a p38 MAPK-dependent, p-aminosalicylic acid-sensitive signaling cascade.

Matrix metalloproteinases in tuberculosis.

Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.

Molecular Imaging in TB: From the Bench to the Clinic

Monocyte-Dependent Fibroblast CXCL8 Secretion Occurs in Tuberculosis and Limits Survival of Mycobacteria within Macrophages

Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo.

Monocyte-dependent oncostatin M and TNF-alpha synergize to stimulate unopposed matrix metalloproteinase-1/3 secretion from human lung fibroblasts in tuberculosis

Monocytes infected with Mycobacterium tuberculosis regulate MAP kinase-dependent astrocyte MMP-9 secretion

Multifocal cortical myoclonus and cerebral amyloid beta-peptide angiopathy

Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation

Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology.

Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch

Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks

Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1.

Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways. ⬇️

Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis

Optimisation of bioluminescent reporters for use with mycobacteria

Pathogenesis of ocular tuberculosis: New observations and future directions

Permutations of time and place in tuberculosis

Personal respirators for population level control of the COVID19 pandemic

Personal respirators for population level control of the COVID19 pandemic

Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis

Quantitative and qualitative iNKT repertoire associations with disease susceptibility and outcome in macaque tuberculosis infection

Reconsidering the Optimal Immune Response to Mycobacterium tuberculosis

Regulation of matrix metalloproteinase-1, -3, and -9 in Mycobacterium tuberculosis-dependent respiratory networks by the rapamycin-sensitive PI3K/p70(S6K) cascade.

Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD.

Repetitive Aerosol Exposure Promotes Cavitary Tuberculosis and Enables Screening for Targeted Inhibitors of Extensive Lung Destruction

STAT3, p38 MAPK, and NF-kappaB drive unopposed monocyte-dependent fibroblast MMP-1 secretion in tuberculosis

Seasonal variation in the performance of QuantiFERON-TB Gold In-Tube assays used for the diagnosis of tuberculosis infection.

Spatz-Lindenberg disease: a rare cause of vascular dementia

Structural and Functional Changes of the Invariant NKT Clonal Repertoire in Early Rheumatoid Arthritis

Synergistic up-regulation of epithelial cell matrix metalloproteinase-9 secretion in tuberculosis.

The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis.

The effect of electromagnetic stimulation of the posterior parietal cortex on eye movements

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

Towards host-directed therapies for tuberculosis