Lista de obras - Andrea Sottoriva - Dominio Público Uruguay

A Big Bang model of human colorectal tumor growth

artículo científico publicado en 2015

Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer

scientific article published on 21 October 2019

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

scientific article published on 01 September 2018

Author Correction: Resolving genetic heterogeneity in cancer

artículo científico publicado en 2020

Between-region genetic divergence reflects the mode and tempo of tumor evolution

artículo científico publicado en 2017

Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

artículo científico publicado en 2016

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

artículo científico publicado en 2010

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer

artículo científico publicado en 2017

Catch my drift? Making sense of genomic intra-tumour heterogeneity

artículo científico publicado en 2017

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

scientific article published on 01 August 2020

Defining stem cell dynamics in models of intestinal tumor initiation

artículo científico publicado en 2013

Detecting repeated cancer evolution from multi-region tumor sequencing data

artículo científico publicado en 2018

Detecting truly clonal alterations from multi-region profiling of tumours

artículo científico publicado en 2017

Evolutionary dynamics of neoantigens in growing tumors

artículo científico publicado en 2020

Evolutionary dynamics of residual disease in human glioblastoma

artículo científico publicado en 2019

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

scientific article published on 21 April 2020

Exploring cancer stem cell niche directed tumor growth.

artículo científico publicado en 2010

Identification of neutral tumor evolution across cancer types.

artículo científico publicado en 2016

Immunosuppressive niche engineering at the onset of human colorectal cancer

artículo científico publicado en 2022

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

artículo científico publicado en 2013

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.

artículo científico publicado en 2018

Many private mutations originate from the first few divisions of a human colorectal adenoma.

artículo científico publicado en 2015

Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

scientific article published on 27 March 2020

Measuring cancer evolution from the genome.

artículo científico publicado en 2016

Measuring single cell divisions in human tissues from multi-region sequencing data

artículo científico publicado en 2020

Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

artículo científico publicado en 2020

Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

scientific article published in Nature Communications

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

artículo científico publicado en 2018

Phenotypic plasticity and genetic control in colorectal cancer evolution

artículo científico publicado en 2022

Quantification of subclonal selection in cancer from bulk sequencing data

artículo científico publicado en 2018

Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

artículo científico publicado en 2021

Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'

article by Benjamin Werner et al published 29 October 2018 in Nature Genetics

Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’

scientific article published on 01 December 2018

Reply: Neutral tumor evolution?

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

artículo científico publicado en 2017

Resolving genetic heterogeneity in cancer

scientific article published on 01 July 2019

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

artículo científico publicado en 2017

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

artículo científico publicado en 2019

Subclonal reconstruction of tumors by using machine learning and population genetics

scientific article published on 02 September 2020

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

artículo científico publicado en 2016

The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer

artículo científico publicado en 2018

The evolutionary landscape of colorectal tumorigenesis ⬇️

scientific article published on 31 August 2018

The shaping and functional consequences of the microRNA landscape in breast cancer

artículo científico publicado en 2013

Lista de obras de Andrea Sottoriva

A Big Bang model of human colorectal tumor growth

Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

Author Correction: Resolving genetic heterogeneity in cancer

Between-region genetic divergence reflects the mode and tempo of tumor evolution

Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer

Catch my drift? Making sense of genomic intra-tumour heterogeneity

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

Defining stem cell dynamics in models of intestinal tumor initiation

Detecting repeated cancer evolution from multi-region tumor sequencing data

Detecting truly clonal alterations from multi-region profiling of tumours

Evolutionary dynamics of neoantigens in growing tumors

Evolutionary dynamics of residual disease in human glioblastoma

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Exploring cancer stem cell niche directed tumor growth.

Identification of neutral tumor evolution across cancer types.

Immunosuppressive niche engineering at the onset of human colorectal cancer

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.

Many private mutations originate from the first few divisions of a human colorectal adenoma.

Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

Measuring cancer evolution from the genome.

Measuring single cell divisions in human tissues from multi-region sequencing data

Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

Phenotypic plasticity and genetic control in colorectal cancer evolution

Quantification of subclonal selection in cancer from bulk sequencing data

Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Reply to 'Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution'

Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’

Reply: Neutral tumor evolution?

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

Resolving genetic heterogeneity in cancer

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

Subclonal reconstruction of tumors by using machine learning and population genetics

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer

The evolutionary landscape of colorectal tumorigenesis ⬇️

The shaping and functional consequences of the microRNA landscape in breast cancer