Lista de obras - Alessandro Morotti - Dominio Público Uruguay

Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis

artículo científico publicado en 2002

Association between High On-Aspirin Platelet Reactivity and Reduced Superoxide Dismutase Activity in Patients Affected by Type 2 Diabetes Mellitus or Primary Hypercholesterolemia

artículo científico publicado en 2020

BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP.

artículo científico publicado en 2013

BCR-ABL inactivates cytosolic PTEN through Casein Kinase II mediated tail phosphorylation.

artículo científico publicado en 2015

BCR-ABL promotes PTEN downregulation in chronic myeloid leukemia.

artículo científico publicado en 2014

Bortezomib-mediated proteasome inhibition as a potential strategy for the treatment of rhabdomyosarcoma

artículo científico publicado en 2008

CD7/CD56-positive acute myeloid leukemias are characterized by constitutive phosphorylation of the NF-kB subunit p65 at Ser536

artículo científico publicado en 2007

DOK2 inhibits EGFR-mutated lung adenocarcinoma

artículo científico publicado en 2013

De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways

artículo científico publicado en 2019

Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma

artículo científico publicado en 2016

Detection and management of retroperitoneal cystic lesions: A case report and review of the literature.

artículo científico publicado en 2017

Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room

artículo científico publicado en 2015

Gastropancreatic fistula in a patient with chronic pancreatitis and IPMN.

artículo científico publicado en 2016

HAUSP compartmentalization in chronic myeloid leukemia.

artículo científico publicado en 2014

HHV8-positive, HIV-negative multicentric Castleman's disease: early and sustained complete remission with rituximab therapy without reactivation of Kaposi sarcoma.

artículo científico publicado en 2009

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

artículo científico publicado en 2016

Identification of DOK genes as lung tumor suppressors

artículo científico publicado en 2010

Increase in platelet count in older, poor-risk patients with acute myeloid leukemia or myelodysplastic syndrome treated with valproic acid and all-trans retinoic acid

artículo científico publicado en 2005

Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations

artículo científico publicado en 2008

Inhibition of bromodomain and extra-terminal proteins increases sensitivity to venetoclax in chronic lymphocytic leukaemia

scientific article published on 10 December 2019

IκB-α: At the crossroad between oncogenic and tumor-suppressive signals.

artículo científico publicado en 2016

K252a inhibits the oncogenic properties of Met, the HGF receptor

artículo científico publicado en 2002

Kinase-inhibitor-insensitive cancer stem cells in chronic myeloid leukemia

artículo científico publicado en 2014

Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex

artículo científico publicado en 2016

Milestones and monitoring

artículo científico publicado en 2015

Modeling myeloproliferative neoplasms: From mutations to mouse models and back again

artículo científico publicado en 2016

Morgana acts as an oncosuppressor in chronic myeloid leukemia.

artículo científico publicado en 2015

NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line.

artículo científico publicado en 2006

New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia.

artículo científico publicado en 2015

Non genomic loss of function of tumor suppressors in CML: BCR-ABL promotes IκBα mediated p53 nuclear exclusion

artículo científico publicado en 2015

Nuclear-cytoplasmic Shuttling in Chronic Myeloid Leukemia: Implications in Leukemia Maintenance and Therapy

artículo científico publicado en 2019

Phenotypical heterogeneity of acute myeloid leukemia in the elderly: a clue for a personalized therapy?

scientific article published on 13 January 2020

Platelet function and activation markers in primary hypercholesterolemia treated with anti-PCSK9 monoclonal antibody: A 12-month follow-up

scientific article published on 17 September 2019

Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias

artículo científico publicado en 2015

Quantitative assessment of WT1 expression in diagnosis of childhood acute leukemia

scientific article published on 31 July 2006

RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis.

artículo científico publicado en 2005

Rare Bone Marrow Biopsy Complication: A Challenging Case of Sacroiliitis and Staphilococcus Aureus Sepsis

artículo científico publicado en 2016

Rational approaches to the design of therapeutics targeting molecular markers: the case of chronic myelogenous leukemia

artículo científico publicado en 2004

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.

artículo científico publicado en 2014

Rhino-Orbital-Cerebral Mucormycosis after Allogeneic Hematopoietic Stem Cell Transplantation and Isavuconazole Therapeutic Drug Monitoring during Intestinal Graft versus Host Disease

artículo científico publicado en 2019

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.

artículo científico publicado en 2018

Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation.

artículo científico publicado en 2004

Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells

scientific article published on 06 November 2019

Targeting few to help hundreds: JAK, MAPK and ROCK pathways as druggable targets in atypical chronic myeloid leukemia.

artículo científico publicado en 2018

Thalidomide-induced partial stable remission in a case of refractory progressive B Cell Chronic Lymphoid Leukemia

artículo científico publicado en 2007

The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias

artículo científico publicado en 2016

The Challenge of Hemorrhagic Shock Management During Low-Molecular-Weight Heparin Treatment

artículo científico publicado en 2020

The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.

artículo científico publicado en 2017

The Role of PTEN in Myeloid Malignancies

artículo científico publicado en 2015

The challenging diagnosis of pancreatic masses: not all tumors are cancers.

artículo científico publicado en 2015

The non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phase

artículo científico publicado en 2016

The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia.

artículo científico publicado en 2016

Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones

artículo científico publicado en 2017

Transferrin Saturation Inversely Correlates with Platelet Function

artículo científico publicado en 2019

Tumor Suppressors in Chronic Lymphocytic Leukemia: From Lost Partners to Active Targets

scientific article published on 09 March 2020

Tumor suppressors revival in CLL

artículo científico publicado en 2017

Unleashing the Guardian: The Targetable BCR-ABL/HAUSP/PML/PTEN Network in Chronic Myeloid Leukemia

artículo científico publicado en 2016

Update on emerging treatments for chronic myeloid leukemia.

artículo científico

Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells

artículo científico publicado en 2006

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

artículo científico publicado en 2016

When collateral vessels matter: asymptomatic Leriche syndrome

artículo científico publicado en 2015

Lista de obras de Alessandro Morotti

Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis

Association between High On-Aspirin Platelet Reactivity and Reduced Superoxide Dismutase Activity in Patients Affected by Type 2 Diabetes Mellitus or Primary Hypercholesterolemia

BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP.

BCR-ABL inactivates cytosolic PTEN through Casein Kinase II mediated tail phosphorylation.

BCR-ABL promotes PTEN downregulation in chronic myeloid leukemia.

Bortezomib-mediated proteasome inhibition as a potential strategy for the treatment of rhabdomyosarcoma

CD7/CD56-positive acute myeloid leukemias are characterized by constitutive phosphorylation of the NF-kB subunit p65 at Ser536

DOK2 inhibits EGFR-mutated lung adenocarcinoma

De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways

Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma

Detection and management of retroperitoneal cystic lesions: A case report and review of the literature.

Emergency management of major bleeding in a case of maxillofacial trauma and anticoagulation: utility of prothrombin complex concentrates in the shock room

Gastropancreatic fistula in a patient with chronic pancreatitis and IPMN.

HAUSP compartmentalization in chronic myeloid leukemia.

HHV8-positive, HIV-negative multicentric Castleman's disease: early and sustained complete remission with rituximab therapy without reactivation of Kaposi sarcoma.

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

Identification of DOK genes as lung tumor suppressors

Increase in platelet count in older, poor-risk patients with acute myeloid leukemia or myelodysplastic syndrome treated with valproic acid and all-trans retinoic acid

Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations

Inhibition of bromodomain and extra-terminal proteins increases sensitivity to venetoclax in chronic lymphocytic leukaemia

IκB-α: At the crossroad between oncogenic and tumor-suppressive signals.

K252a inhibits the oncogenic properties of Met, the HGF receptor

Kinase-inhibitor-insensitive cancer stem cells in chronic myeloid leukemia

Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex

Milestones and monitoring

Modeling myeloproliferative neoplasms: From mutations to mouse models and back again

Morgana acts as an oncosuppressor in chronic myeloid leukemia.

NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line.

New alternative splicing BCR/ABL-OOF shows an oncogenic role by lack of inhibition of BCR GTPase activity and an increased of persistence of Rac activation in chronic myeloid leukemia.

Non genomic loss of function of tumor suppressors in CML: BCR-ABL promotes IκBα mediated p53 nuclear exclusion

Nuclear-cytoplasmic Shuttling in Chronic Myeloid Leukemia: Implications in Leukemia Maintenance and Therapy

Phenotypical heterogeneity of acute myeloid leukemia in the elderly: a clue for a personalized therapy?

Platelet function and activation markers in primary hypercholesterolemia treated with anti-PCSK9 monoclonal antibody: A 12-month follow-up

Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias

Quantitative assessment of WT1 expression in diagnosis of childhood acute leukemia

RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis.

Rare Bone Marrow Biopsy Complication: A Challenging Case of Sacroiliitis and Staphilococcus Aureus Sepsis

Rational approaches to the design of therapeutics targeting molecular markers: the case of chronic myelogenous leukemia

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.

Rhino-Orbital-Cerebral Mucormycosis after Allogeneic Hematopoietic Stem Cell Transplantation and Isavuconazole Therapeutic Drug Monitoring during Intestinal Graft versus Host Disease

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.

Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation.

Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells

Targeting few to help hundreds: JAK, MAPK and ROCK pathways as druggable targets in atypical chronic myeloid leukemia.

Thalidomide-induced partial stable remission in a case of refractory progressive B Cell Chronic Lymphoid Leukemia

The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias

The Challenge of Hemorrhagic Shock Management During Low-Molecular-Weight Heparin Treatment

The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.

The Role of PTEN in Myeloid Malignancies

The challenging diagnosis of pancreatic masses: not all tumors are cancers.

The non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phase

The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia.

Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones

Transferrin Saturation Inversely Correlates with Platelet Function

Tumor Suppressors in Chronic Lymphocytic Leukemia: From Lost Partners to Active Targets

Tumor suppressors revival in CLL

Unleashing the Guardian: The Targetable BCR-ABL/HAUSP/PML/PTEN Network in Chronic Myeloid Leukemia

Update on emerging treatments for chronic myeloid leukemia.

Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

When collateral vessels matter: asymptomatic Leriche syndrome