Lista de obras - Jonathan D. Mosley - Dominio Público Uruguay

A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin

artículo científico publicado en 2016

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

artículo científico publicado en 2015

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

artículo científico publicado en 2014

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

artículo científico publicado en 2018

Association of Thyroid Function Genetic Predictors With Atrial Fibrillation: A Phenome-Wide Association Study and Inverse-Variance Weighted Average Meta-analysis

scientific article published on 01 February 2019

Benefit of pre-emptive pharmacogenetic information on clinical outcome

artículo científico publicado en 2018

Biobanks and electronic medical records: enabling cost-effective research

artículo científico publicado en 2014

Cardiovascular risk factors in normotensive and hypertensive Egyptians.

artículo científico publicado en 2001

Clinical Features Associated With Nascent Left Ventricular Diastolic Dysfunction in a Population Aged 40 to 55 Years

scientific article published on 13 March 2018

Comparison of HLA allelic imputation programs.

artículo científico publicado en 2017

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data

artículo científico publicado en 2016

Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects

artículo científico publicado en 2018

Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome

artículo científico publicado en 2014

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

artículo científico publicado en 2010

Finding a Needle in a QT Interval Big Data Haystack

artículo científico publicado en 2016

Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease

scientific article published on 03 December 2019

Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.

artículo científico publicado en 2014

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

scientific article published on 05 March 2013

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults.

artículo científico publicado en 2017

Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

artículo científico publicado en 2017

Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease

artículo científico publicado en 2002

Identifying genetically driven clinical phenotypes using linear mixed models

artículo científico publicado en 2016

Influence of human leukocyte antigen (HLA) alleles and killer cell immunoglobulin-like receptors (KIR) types on heparin-induced thrombocytopenia (HIT).

artículo científico publicado en 2017

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations

artículo científico publicado en 2014

Intrinsic bias in breast cancer gene expression data sets

artículo científico publicado en 2009

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes

artículo científico publicado en 2017

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins

Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica

article

Letter by Mosley Regarding Article, "Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat".

artículo científico publicado en 2015

Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases

artículo científico publicado en 2001

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data

artículo científico publicado en 2013

Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation

artículo científico publicado en 2018

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

artículo científico publicado en 2014

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

artículo científico publicado en 2017

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

scientific article published in Science

QT variability during initial exposure to sotalol: experience based on a large electronic medical record.

artículo científico publicado en 2013

Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer

artículo científico publicado en 2007

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records

artículo científico publicado en 2018

Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.

artículo científico publicado en 2014

Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis

artículo científico publicado en 2006

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

artículo científico publicado en 2013

The polygenic architecture of left ventricular mass mirrors the clinical epidemiology

scientific article published on 05 May 2020

Using systems approaches to address challenges for clinical implementation of pharmacogenomics

Using systems approaches to address challenges for clinical implementation of pharmacogenomics.

artículo científico publicado en 2013

Validation and enhancement of a computable medication indication resource (MEDI) using a large practice-based dataset

artículo científico publicado en 2013

Whole-exome sequencing in familial atrial fibrillation.

artículo científico publicado en 2014

Lista de obras de Jonathan D. Mosley

A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

Association of Thyroid Function Genetic Predictors With Atrial Fibrillation: A Phenome-Wide Association Study and Inverse-Variance Weighted Average Meta-analysis

Benefit of pre-emptive pharmacogenetic information on clinical outcome

Biobanks and electronic medical records: enabling cost-effective research

Cardiovascular risk factors in normotensive and hypertensive Egyptians.

Clinical Features Associated With Nascent Left Ventricular Diastolic Dysfunction in a Population Aged 40 to 55 Years

Comparison of HLA allelic imputation programs.

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data

Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects

Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

Finding a Needle in a QT Interval Big Data Haystack

Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease

Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults.

Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease

Identifying genetically driven clinical phenotypes using linear mixed models

Influence of human leukocyte antigen (HLA) alleles and killer cell immunoglobulin-like receptors (KIR) types on heparin-induced thrombocytopenia (HIT).

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations

Intrinsic bias in breast cancer gene expression data sets

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes

LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins

Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica

Letter by Mosley Regarding Article, "Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat".

Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data

Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

QT variability during initial exposure to sotalol: experience based on a large electronic medical record.

Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records

Screening for acute IKr block is insufficient to detect torsades de pointes liability: role of late sodium current.

Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

The polygenic architecture of left ventricular mass mirrors the clinical epidemiology

Using systems approaches to address challenges for clinical implementation of pharmacogenomics

Using systems approaches to address challenges for clinical implementation of pharmacogenomics.

Validation and enhancement of a computable medication indication resource (MEDI) using a large practice-based dataset

Whole-exome sequencing in familial atrial fibrillation.