Lista de obras - Matti Nykter - Dominio Público Uruguay

A data integration framework for prediction of transcription factor targets

artículo científico publicado en 2009

A linear model for transcription factor binding affinity prediction in protein binding microarrays

artículo científico publicado en 2011

A systems biological approach to identify key transcription factors and their genomic neighborhoods in human sarcomas ⬇️

artículo científico publicado el 1 de enero de 2011

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

artículo científico publicado en 2015

Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.

artículo científico publicado en 2017

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

artículo científico

Assessment of PARP protein expression in epithelial ovarian cancer by ELISA pharmacodynamic assay and immunohistochemistry

artículo científico

Balance between noise and information flow maximizes set complexity of network dynamics ⬇️

artículo científico publicado en 2013

Bioinformatics Assembling and Assessment of Novel Coxsackievirus B1 Genome

artículo científico publicado en 2018

Biological Information as Set-Based Complexity

artículo científico publicado en 2010

Bone morphogenetic protein 4 regulates microRNA expression in breast cancer cell lines in diverse fashion

artículo científico publicado en 2015

Cancer genome sequencing: understanding malignancy as a disease of the genome, its conformation, and its evolution.

artículo científico publicado en 2013

Characterization of aberrant pathways across human cancers

artículo científico publicado en 2013

Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio).

artículo científico publicado en 2018

Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer

scientific article published on 10 January 2019

Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer.

artículo científico publicado en 2017

Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages.

artículo científico publicado en 2017

Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis

artículo científico publicado en 2011

Circulating tumor DNA genomics correlate with resistance to abiraterone and enzalutamide in prostate cancer

artículo científico publicado en 2018

Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas.

artículo científico publicado en 2017

Comparative Analysis of Tissue Reconstruction Algorithms for 3D Histology.

artículo científico publicado en 2018

Comparative analysis of osteoblast gene expression profiles and Runx2 genomic occupancy of mouse and human osteoblasts in vitro

artículo científico

Comparison of iTRAQ and SWATH in a clinical study with multiple time points

scholarly article by Antti Jylhä published in January 2018

Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma

artículo científico publicado en 2018

Computational methods for estimation of cell cycle phase distributions of yeast cells

artículo científico

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.

artículo científico publicado en 2017

Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases

scientific article published on 10 July 2018

Construction of therapeutically relevant human prostate epithelial fate map by utilising miRNA and mRNA microarray expression data

artículo científico publicado en 2015

Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma

scientific article published on 09 November 2017

DOT1L-HES6 fusion drives androgen independent growth in prostate cancer

artículo científico publicado en 2014

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

artículo científico publicado en 2018

Epigenetically altered miR-193b targets cyclin D1 in prostate cancer

artículo científico publicado en 2015

Erratum: Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma

artículo científico publicado en 2018

Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster

artículo científico publicado en 2019

Expression Analysis of Platinum Sensitive and Resistant Epithelial Ovarian Cancer Patient Samples Reveals New Candidates for Targeted Therapies

artículo científico publicado en 2018

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene

artículo científico publicado en 2016

Extensive reprogramming of the nascent transcriptome during iPSC to hepatocyte differentiation

artículo científico publicado en 2019

Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.

artículo científico publicado en 2017

Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections.

artículo científico publicado en 2016

Frequent mutation of the untranslated region in prostate cancer

article

Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

artículo científico publicado en 2009

Gene expression dynamics in the macrophage exhibit criticality

artículo científico publicado en 2008

Gene-pair expression signatures reveal lineage control

artículo científico publicado en 2013

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia

artículo científico publicado en 2016

Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer

artículo científico publicado en 2016

Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment ⬇️

artículo científico publicado el 31 de octubre de 2011

Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

artículo científico publicado en 2015

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

scientific article published on 02 April 2019

Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

artículo científico publicado en 2021

Information diversity in structure and dynamics of simulated neuronal networks

artículo científico publicado en 2011

Information-theoretic analysis of the dynamics of an executable biological model

artículo científico publicado en 2013

Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network

artículo científico publicado en 2012

Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer.

artículo científico publicado en 2017

Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer

artículo científico publicado en 2013

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.

artículo científico publicado en 2016

Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors

artículo científico publicado en 2010

Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

artículo científico publicado en 2018

Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection

artículo científico publicado en 2018

Karyotypically abnormal human ESCs are sensitive to HDAC inhibitors and show altered regulation of genes linked to cancers and neurological diseases

artículo científico publicado en 2013

Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro

artículo científico publicado en 2017

Leukemia prediction using sparse logistic regression

artículo científico publicado en 2013

Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer

artículo científico publicado en 2013

Metastasis detection from whole slide images using local features and random forests.

artículo científico publicado en 2017

MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2.

artículo científico publicado en 2015

Microarray analysis of differentially expressed genes in ovarian and fallopian tube epithelium from risk-reducing salpingo-oophorectomies.

artículo científico publicado en 2015

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer

artículo científico publicado en 2016

Modes of immunosuppression in glioblastoma microenvironment

scientific article published on 29 January 2019

Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center

artículo científico publicado en 2017

Myeloid cell expressed proprotein convertase FURIN attenuates inflammation

scientific article published on 05 August 2016

NRF2, DJ1 and SNRX1 and their prognostic impact in astrocytic gliomas

artículo científico publicado en 2018

Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT.

artículo científico publicado en 2017

Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.

artículo científico publicado en 2016

POMO--Plotting Omics analysis results for Multiple Organisms

artículo científico publicado en 2013

Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).

artículo científico publicado en 2013

Proteomics of prostate cancer - revealing how cancer cells master their messy genomes

scientific article published on 31 July 2018

Quantitative analysis of colony morphology in yeast

artículo científico publicado en 2014

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells

artículo científico publicado en 2017

Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma

artículo científico publicado en 2014

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer.

artículo científico publicado en 2015

Segmentum: a tool for copy number analysis of cancer genomes

artículo científico publicado en 2017

Simulation of microarray data with realistic characteristics.

artículo científico publicado en 2006

Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse

artículo científico publicado en 2021

Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas.

artículo científico publicado en 2017

The evolutionary history of lethal metastatic prostate cancer

artículo científico publicado en 2015

The expression of AURKA is androgen regulated in castration-resistant prostate cancer.

artículo científico publicado en 2017

The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

artículo científico publicado en 2013

Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.

artículo científico publicado en 2017

Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.

artículo científico publicado en 2013

Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.

artículo científico publicado en 2015

Transcriptome and small RNA deep sequencing reveals deregulation of miRNA biogenesis in human glioma

artículo científico publicado en 2013

Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair-deficient Prostate Cancer

artículo científico publicado en 2017

Twist predicts poor outcome of patients with astrocytic glioma

artículo científico publicado en 2015

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma

artículo científico publicado en 2014

Unsupervised analysis uncovers changes in histopathologic diagnosis in supervised genomic studies

artículo científico publicado en 2006

Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.

artículo científico publicado en 2017

Virtual cell imaging: A review on simulation methods employed in image cytometry

artículo científico publicado en 2016

Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma

artículo científico publicado en 2018

Whole-exome sequencing of Finnish hereditary breast cancer families

artículo científico publicado en 2016

Lista de obras de Matti Nykter

A data integration framework for prediction of transcription factor targets

A linear model for transcription factor binding affinity prediction in protein binding microarrays

A systems biological approach to identify key transcription factors and their genomic neighborhoods in human sarcomas ⬇️

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

Assessment of PARP protein expression in epithelial ovarian cancer by ELISA pharmacodynamic assay and immunohistochemistry

Balance between noise and information flow maximizes set complexity of network dynamics ⬇️

Bioinformatics Assembling and Assessment of Novel Coxsackievirus B1 Genome

Biological Information as Set-Based Complexity

Bone morphogenetic protein 4 regulates microRNA expression in breast cancer cell lines in diverse fashion

Cancer genome sequencing: understanding malignancy as a disease of the genome, its conformation, and its evolution.

Characterization of aberrant pathways across human cancers

Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio).

Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer

Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer.

Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages.

Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis

Circulating tumor DNA genomics correlate with resistance to abiraterone and enzalutamide in prostate cancer

Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas.

Comparative Analysis of Tissue Reconstruction Algorithms for 3D Histology.

Comparative analysis of osteoblast gene expression profiles and Runx2 genomic occupancy of mouse and human osteoblasts in vitro

Comparison of iTRAQ and SWATH in a clinical study with multiple time points

Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma

Computational methods for estimation of cell cycle phase distributions of yeast cells

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer.

Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases

Construction of therapeutically relevant human prostate epithelial fate map by utilising miRNA and mRNA microarray expression data

Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma

DOT1L-HES6 fusion drives androgen independent growth in prostate cancer

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Epigenetically altered miR-193b targets cyclin D1 in prostate cancer

Erratum: Whole-exome sequencing identifies germline mutation in TP53 and ATRX in a child with genomically aberrant AT/RT and her mother with anaplastic astrocytoma

Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster

Expression Analysis of Platinum Sensitive and Resistant Epithelial Ovarian Cancer Patient Samples Reveals New Candidates for Targeted Therapies

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene

Extensive reprogramming of the nascent transcriptome during iPSC to hepatocyte differentiation

Feasibility of Prostate PAXgene Fixation for Molecular Research and Diagnostic Surgical Pathology: Comparison of Matched Fresh Frozen, FFPE, and PFPE Tissues.

Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections.

Frequent mutation of the untranslated region in prostate cancer

Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

Gene expression dynamics in the macrophage exhibit criticality

Gene-pair expression signatures reveal lineage control

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia

Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer

Genomic and Molecular Characterization of Malignant Peripheral Nerve Sheath Tumor Identifies the IGF1R Pathway as a Primary Target for Treatment ⬇️

Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

Information diversity in structure and dynamics of simulated neuronal networks

Information-theoretic analysis of the dynamics of an executable biological model

Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network

Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer.

Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer.

Integrative genomic characterization and a genomic staging system for gastrointestinal stromal tumors

Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection

Karyotypically abnormal human ESCs are sensitive to HDAC inhibitors and show altered regulation of genes linked to cancers and neurological diseases

Laminin α5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro

Leukemia prediction using sparse logistic regression

Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer

Metastasis detection from whole slide images using local features and random forests.

MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2.

Microarray analysis of differentially expressed genes in ovarian and fallopian tube epithelium from risk-reducing salpingo-oophorectomies.

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer

Modes of immunosuppression in glioblastoma microenvironment

Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center

Myeloid cell expressed proprotein convertase FURIN attenuates inflammation

NRF2, DJ1 and SNRX1 and their prognostic impact in astrocytic gliomas

Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT.

Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.

POMO--Plotting Omics analysis results for Multiple Organisms

Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).

Proteomics of prostate cancer - revealing how cancer cells master their messy genomes

Quantitative analysis of colony morphology in yeast

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA+ and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells

Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer.