Lista de obras - Marina Pajic - Dominio Público Uruguay

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

artículo científico publicado en 2017

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

artículo científico publicado en 2011

ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumors

scientific article published on 03 August 2018

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

artículo científico publicado en 2013

An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences

artículo científico publicado en 2014

BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma

artículo científico publicado en 2018

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

artículo científico publicado en 2013

Clinical and pathologic features of familial pancreatic cancer

artículo científico publicado en 2014

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

artículo científico publicado en 2004

Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

artículo científico publicado en 2017

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

artículo científico publicado en 2016

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

artículo científico publicado en 2014

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

artículo científico publicado en 2014

Genomic analyses identify molecular subtypes of pancreatic cancer

artículo científico publicado en 2016

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

artículo científico publicado en 2016

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

artículo científico publicado en 2013

Hypermutation In Pancreatic Cancer

artículo científico publicado en 2016

Imaging fibrosis in pancreatic cancer using second harmonic generation

scientific article published on 01 March 2015

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors

artículo científico publicado en 2012

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

artículo científico publicado en 2018

Lost in translation: returning germline genetic results in genome-scale cancer research

artículo científico publicado en 2017

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

scientific article published on 01 June 2020

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

scientific article published on 30 January 2017

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

article

Nucleus pulposus cellular longevity by telomerase gene therapy

artículo científico publicado en 2007

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

artículo científico publicado en 2012

Personalising pancreas cancer treatment: When tissue is the issue

artículo científico publicado en 2014

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial

artículo científico

Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer

artículo científico publicado en 2018

Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes

scientific article published on 23 April 2011

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction

artículo científico publicado en 2011

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.

artículo científico publicado en 2017

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

artículo científico publicado en 2016

Returning individual research results for genome sequences of pancreatic cancer

artículo científico publicado en 2014

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarinoma Invasion and Tumor Growth.

artículo científico publicado en 2018

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities

artículo científico publicado en 2015

SOX9 regulates ERBB signalling in pancreatic cancer development.

artículo científico publicado en 2014

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials

artículo científico publicado en 2015

Selected alkylating agents can overcome drug tolerance of G0-like tumor cells and eradicate BRCA1-deficient mammary tumors in mice

artículo científico publicado en 2017

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

artículo científico publicado en 2007

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan

artículo científico publicado en 2010

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.

artículo científico publicado en 2017

Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma

artículo científico publicado en 2009

Somatic point mutation calling in low cellularity tumors.

artículo científico publicado en 2013

Studying drug resistance using genetically engineered mouse models for breast cancer

artículo científico publicado en 2010

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer

artículo científico publicado en 2017

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

artículo científico publicado en 2020

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy.

artículo científico publicado en 2017

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

scientific article published on 05 August 2019

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma

article published in 2018

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models

artículo científico publicado en 2016

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment

artículo científico publicado en 2015

The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo.

artículo científico publicado en 2015

The prognostic and predictive value of serum CA19.9 in pancreatic cancer

artículo científico publicado en 2012

The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome

artículo científico publicado en 2005

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

artículo científico publicado en 2017

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

artículo científico publicado en 2017

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

artículo científico publicado en 2017

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo

artículo científico publicado en 2010

Understanding pancreatic cancer genomes

artículo científico publicado en 2013

Whole genomes redefine the mutational landscape of pancreatic cancer

artículo científico publicado en 2015

Whole-genome landscape of pancreatic neuroendocrine tumours.

artículo científico publicado en 2017

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense

artículo científico publicado en 2017

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

artículo científico publicado en 2012

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

artículo científico publicado en 2018

Lista de obras de Marina Pajic

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.

ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.

ATRX loss is an independent predictor of poor survival in pancreatic neuroendocrine tumors

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences

BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

Clinical and pathologic features of familial pancreatic cancer

Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines

Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

Genomic analyses identify molecular subtypes of pancreatic cancer

Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis.

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

Hypermutation In Pancreatic Cancer

Imaging fibrosis in pancreatic cancer using second harmonic generation

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer.

Lost in translation: returning germline genetic results in genome-scale cancer research

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

Nucleus pulposus cellular longevity by telomerase gene therapy

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Personalising pancreas cancer treatment: When tissue is the issue

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial

Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer

Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction

Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

Returning individual research results for genome sequences of pancreatic cancer

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarinoma Invasion and Tumor Growth.

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities

SOX9 regulates ERBB signalling in pancreatic cancer development.

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials

Selected alkylating agents can overcome drug tolerance of G0-like tumor cells and eradicate BRCA1-deficient mammary tumors in mice

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.

Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma

Somatic point mutation calling in low cellularity tumors.

Studying drug resistance using genetically engineered mouse models for breast cancer

Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy.

Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models

The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment

The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo.

The prognostic and predictive value of serum CA19.9 in pancreatic cancer

The role of the multidrug resistance-associated protein 1 gene in neuroblastoma biology and clinical outcome

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.

Transient targeting of the pancreatic cancer stroma as a 'fine-tuned' anti-tumor and anti-metastatic therapy.

Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo

Understanding pancreatic cancer genomes

Whole genomes redefine the mutational landscape of pancreatic cancer

Whole-genome landscape of pancreatic neuroendocrine tumours.

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling