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Lista de obras de Rupert M Pearse

A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study.

artículo científico publicado en 2017

A national early warning score for acutely ill patients

artículo científico publicado en 2012

A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT

artículo científico publicado en 2019

A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.

artículo científico publicado en 2018

A systematic review and meta-analysis of return to work after mild Traumatic brain injury

artículo científico publicado en 2018

A systematic review of the role of cardiopulmonary exercise testing in vascular surgery.

artículo científico

Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy.

artículo científico publicado en 2016

Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study

artículo científico publicado en 2019

Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model.

artículo científico publicado en 2018

Acute kidney injury and mortality 1 year after major non-cardiac surgery.

artículo científico publicado en 2017

Age of patients undergoing surgery

artículo científico publicado en 2019

American Society of Anesthesiologists Score: still useful after 60 years? Results of the EuSOS Study

artículo científico publicado en 2015

An analysis of admission, discharge and bed occupancy of stroke patients aged 65 and over in English hospitals.

artículo científico publicado en 1998

An individual patient meta-analysis of clinical trials using dopexamine to increase oxygen delivery in high-risk surgical patients.

artículo científico publicado en 2007

Anaesthesia research capacity: time for a rethink in light of the COVID-19 pandemic

scientific article published on 22 October 2020

Another inconvenient truth: meeting the challenge of preventing poor surgical outcomes

artículo científico publicado en 2010

Are we close to the ideal intravenous fluid?

scientific article published on 01 December 2017

Arterial pulse pressure and postoperative morbidity in high-risk surgical patients.

artículo científico publicado en 2017

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study

scientific article published on 01 June 2018

Association Between Myocardial Injury and Cardiovascular Outcomes of Orthopaedic Surgery: A Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Substudy

artículo científico publicado en 2020

Association between complications and death within 30 days after noncardiac surgery

scientific article published on 1 July 2019

Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients.

artículo científico publicado en 2015

Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients.

artículo científico publicado en 2014

Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery.

artículo científico publicado en 2015

Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery

artículo científico publicado en 2012

Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery.

artículo científico publicado en 2017

Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery

artículo científico publicado en 2017

Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low-, middle-, and high-income countries

scientific article published on 25 October 2018

Can we safely continue to offer surgical treatments during the COVID-19 pandemic?

scientific article published on 20 November 2020

Cardiac Troponins in Sepsis

scientific article published on 01 April 2014

Cardiac output monitoring: basic science and clinical application.

artículo científico publicado en 2008

Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study.

artículo científico publicado en 2018

Changes in gene expression following trauma are related to the age of transfused packed red blood cells.

artículo científico publicado en 2015

Comparison of the prognostic accuracy of scoring systems, cardiopulmonary exercise testing, and plasma biomarkers: a single-centre observational pilot study

artículo científico publicado en 2013

Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery.

artículo científico publicado en 2009

Correction to: Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial)

artículo científico publicado en 2018

Correction. Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicenter prospective cohort study of cardiopulmonary exercise testing prior to major noncardiac surgery

artículo científico publicado en 2016

Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery

artículo científico publicado en 2015

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

artículo científico publicado en 2017

Critical care admission of South African (SA) surgical patients: Results of the SA Surgical Outcomes Study.

artículo científico publicado en 2017

Current research priorities in perioperative intensive care medicine.

artículo científico

Current use of vasopressors in septic shock

artículo científico publicado en 2019

Do integrated care pathways have a place in critical care?

artículo científico

Does major surgery induce immune suppression and increase the risk of postoperative infection?

artículo científico publicado en 2016

Dopexamine and survival: areas of consistency

artículo científico publicado en 2009

Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow

artículo científico publicado en 2013

Dynamic preload markers to predict fluid responsiveness during and after major gastrointestinal surgery: an observational substudy of the OPTIMISE trial.

artículo científico publicado en 2014

EARLY MICROVASCULAR CHANGES IN SEPSIS AND SEVERE SEPSIS

artículo científico publicado en 2010

Early goal directed therapy reduces morbidity and length of hospital stay following high-risk surgery.

artículo científico publicado en 2005

Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review

artículo científico

Effect of day of the week on short- and long-term mortality after emergency general surgery

artículo científico publicado en 2017

Effect of dopexamine infusion on mortality following major surgery: individual patient data meta-regression analysis of published clinical trials

artículo científico publicado en 2008

Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients.

artículo científico publicado en 2017

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study

artículo científico publicado en 2016

Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma.

artículo científico publicado en 2015

Equipment review: an appraisal of the LiDCO plus method of measuring cardiac output

artículo científico publicado en 2004

Ergocalciferol and microcirculatory function in chronic kidney disease and concomitant vitamin d deficiency: an exploratory, double blind, randomised controlled trial.

artículo científico publicado en 2014

EuSOS: European Surgical Outcomes Study

article published in 2011

Evidence-based medicine: the clue is in the name.

artículo científico publicado en 2017

Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry

artículo científico publicado en 2008

Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways.

artículo científico publicado en 2015

Frequency of surgical treatment and related hospital procedures in the UK: a national ecological study using hospital episode statistics.

artículo científico

Functional definition and characterization of acute traumatic coagulopathy

artículo científico publicado en 2011

Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients

artículo científico publicado en 2012

Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial.

artículo científico publicado en 2010

Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2.

artículo científico publicado en 2011

High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study

artículo científico publicado en 2011

Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data

artículo científico publicado en 2019

ICU admission after surgery: who benefits?

artículo científico publicado en 2017

Impact of hepatic venous oxygen efflux and carotid blood flow on the difference between mixed and central venous oxygen saturation

Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial)

artículo científico publicado en 2018

Improving detection of patient deterioration in the general hospital ward environment

artículo científico publicado en 2018

In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study

artículo científico publicado en 2017

Inadequate pre-operative evaluation and preparation 1.

artículo científico publicado en 2001

Incidence and associations of acute kidney injury after major abdominal surgery

artículo científico publicado en 2015

Incidence of postoperative death and acute kidney injury associated with i.v. 6% hydroxyethyl starch use: systematic review and meta-analysis.

artículo científico publicado en 2013

Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial

artículo científico publicado en 2014

Individualised targeted haemodynamic therapy in high-risk surgical patients – Authors' reply

scientific article published on 01 April 2015

Intensive Care after High-risk Surgery: What's in a Name?

artículo científico publicado en 2016

Intensive care admission and hospital mortality in the elderly after non-cardiac surgery

scientific article published on 01 March 2018

Intensive care utilization and outcomes after high-risk surgery in Scotland: a population-based cohort study

artículo científico publicado en 2017

Intrathoracic blood volume measurement: comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution

artículo científico publicado en 2008

Is it the end of the road for synthetic starches in critical illness? No place for hydroxyethyl starch solutions in treatment of patients with sepsis

artículo científico publicado en 2013

LONG-TERM FOLLOW-UP OF SEPSIS INDUCED IMMUNOPARALYSIS

Letter in Response to 'Classification of Traumatic Brain Injury Severity Using Informed Data Reduction in a Series of Binary Classifier Algorithms'.

artículo científico publicado en 2015

Letter in response to 'Classification algorithms for the identification of structural injury in TBI using brain electrical activity'.

artículo científico publicado en 2015

Managing perioperative risk in patients undergoing elective non-cardiac surgery

artículo científico publicado en 2011

Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery

artículo científico publicado en 2016

Medical emergency teams: implementation and outcome measurement.

artículo científico publicado en 2007

Meta-analysis of the association between preoperative anaemia and mortality after surgery.

artículo científico

Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications

artículo científico publicado en 2008

Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis

artículo científico publicado en 2017

Mortality after surgery in Europe - Authors' reply

artículo científico publicado en 2013

Mortality after surgery in Europe: a 7 day cohort study

artículo científico publicado en 2012

Mortality after surgery in Ireland - Authors' reply

artículo científico publicado en 2013

Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust

artículo científico publicado en 2008

Mortality of emergency general surgical patients and associations with hospital structures and processes

artículo científico publicado en 2016

Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes

artículo científico publicado en 2014

Neutrophil gelatinase-associated lipocalin and albuminuria as predictors of acute kidney injury in patients treated with goal-directed haemodynamic therapy after major abdominal surgery

artículo científico publicado en 2013

Non-invasive ventilation to avoid tracheal intubation in a patient with Guillain-Barré syndrome

artículo científico publicado en 2003

Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study

artículo científico publicado en 2015

Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow.

artículo científico publicado en 2013

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usua

scientific article published on 15 January 2019

Organisational failures in urgent and emergency surgery. A potential peri-operative risk factor

artículo científico publicado en 2001

Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy

artículo científico publicado en 2017

Peri-operative goal-directed therapy: A definitive answer remains elusive

artículo científico publicado en 2018

Peri-operative troponin monitoring using a prototype high-sensitivity cardiac troponin I (hs-cTnI) assay: comparisons with hs-cTnT and contemporary cTnI assays

artículo científico publicado en 2013

Perioperative Flüssigkeitstherapie

artículo científico publicado en 2012

Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

artículo científico publicado en 2014

Perioperative cardiovascular monitoring of high-risk patients: a consensus of 12

artículo científico publicado en 2015

Perioperative fluid therapy

artículo científico publicado en 2012

Perioperative haemodynamic therapy: Why are recommendations not being adopted?

scientific article published on 08 January 2019

Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners.

artículo científico publicado en 2018

Perioperative medicine: the future of anaesthesia?

artículo científico publicado en 2012

Perioperative myocardial injury in patients receiving cardiac output-guided haemodynamic therapy: a substudy of the OPTIMISE Trial

artículo científico publicado en 2015

Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients

Point prevalence of surgical checklist use in Europe: relationship with hospital mortality

artículo científico publicado en 2015

Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery

scientific article published in PLoS ONE

Post-operative immune suppression is reversible with interferon gamma and independent of IL-6 pathways.

artículo científico publicado en 2015

Post-operative intensive care: is it really necessary?

scientific article published on 23 September 2019

Postoperative CPAP after major abdominal surgery – Authors' reply

artículo científico publicado en 2022

Pragmatic trials in peri-operative medicine: why, when and how?

artículo científico publicado en 2018

Pre-operative fasting and administration of regular medications in adult patients presenting for elective surgery. Has the new evidence changed practice?

artículo científico publicado en 1999

Pre-specification of statistical analysis approaches in published clinical trial protocols was inadequate

scientific article published on 02 June 2018

Predictive value of S100-B and copeptin for outcomes following seizure: the BISTRO International Cohort Study

artículo científico publicado en 2015

Preoperative N-Terminal Pro-B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery: A Cohort Study

artículo científico publicado en 2019

Preoperative abnormalities in serum sodium concentrations are associated with higher in-hospital mortality in patients undergoing major surgery.

artículo científico publicado en 2016

Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients

artículo científico publicado en 2014

Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study

artículo científico publicado en 2016

Preoperative renal dysfunction and mortality after non-cardiac surgery.

artículo científico publicado en 2016

Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery

artículo científico publicado en 2018

Prognostic studies of perioperative risk: robust methodology is needed.

artículo científico publicado en 2010

Protocolized fluid therapy in brain-dead donors: the multicenter randomized MOnIToR trial

artículo científico publicado en 2015

Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia.

artículo científico publicado en 2018

Regional variation in critical care provision and outcome after high-risk surgery

artículo científico

Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study

artículo científico publicado en 2012

Role of central and mixed venous oxygen saturation measurement in perioperative care.

artículo científico publicado en 2009

Saving money: An ideal driver for improved perioperative care?

artículo científico publicado en 2017

Serum creatinine changes associated with critical illness and detection of persistent renal dysfunction after AKI

artículo científico publicado en 2014

Short-term neurocognitive and symptomatic outcomes following mild traumatic brain injury: A prospective multi-centre observational cohort study

artículo científico publicado en 2017

Should we use central venous saturation to guide management in high-risk surgical patients?

artículo científico publicado en 2006

Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine

artículo científico publicado en 2015

Steroids for cardiac surgery: has the story finally ended?

artículo científico publicado en 2015

Steroids to prevent postextubation laryngeal oedema

scientific article published in The Lancet

Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients

artículo científico publicado en 2012

Surgical activity in England and Wales during the COVID-19 pandemic: a nationwide observational cohort study

artículo científico publicado en 2021

Swedish surgical outcomes study (SweSOS): An observational study on 30-day and 1-year mortality after surgery.

artículo científico publicado en 2015

The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study

artículo científico publicado en 2018

The Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial. Report of the protocol for a pragmatic randomized controlled trial of CPAP to prevent respiratory complications and improve survival following major abdominal surge

artículo científico publicado en 2016

The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock

artículo científico publicado en 2009

The effects of aging on the cutaneous microvasculature ⬇️

artículo científico publicado el 1 de noviembre de 1995

The incidence of myocardial injury following post-operative Goal Directed Therapy

artículo científico publicado en 2007

The relationship between central venous saturation and outcome following high-risk surgery.

artículo científico publicado en 2004

The use of early intervention to prevent postoperative complications.

artículo científico publicado en 2009

The whole truth and nothing but the truth: the need for full reporting of randomised trials

artículo científico publicado en 2015

Transpulmonary lithium indicator dilution: a new method of intrathoracic blood volume measurement.

artículo científico publicado en 2007

Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis.

artículo científico publicado en 2018

Use of hemodynamic algorithm after gastrointestinal surgery--reply

artículo científico publicado en 2014

Use of inotropes and vasopressor agents in critically ill patients.

artículo científico publicado en 2012

Using oxygen delivery targets to optimize resuscitation in critically ill patients.

scientific article published on June 2010

Using the 6-minute walk test to predict disability-free survival after major surgery

scientific article published on 09 October 2018

Variation in haemodynamic monitoring for major surgery in European nations: secondary analysis of the EuSOS dataset.

artículo científico publicado en 2015

Water, taken in moderation, cannot hurt anybody (Mark Twain 1835-1910)

artículo científico publicado en 2010

Where audit meets science: role of reporting and recommendations guidelines in service evaluations

artículo científico publicado en 2018

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