Lista de obras - Scott A. Wildman - Dominio Público Uruguay

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

artículo científico publicado en 2017

A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings

scientific article published on 05 September 2019

Approaches to virtual screening and screening library selection.

artículo científico publicado en 2013

Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.

artículo científico publicado en 2016

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.

artículo científico publicado en 2011

Evaluation of ligand overlap by atomic parameters

artículo científico publicado en 2001

High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.

artículo científico publicado en 2013

Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence

artículo científico publicado en 2016

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

artículo científico

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer

artículo científico publicado en 2014

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

artículo científico publicado en 2014

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.

artículo científico publicado en 2017

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

artículo científico publicado en 2013

Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin

artículo científico publicado en 2019

Practical Model Selection for Prospective Virtual Screening

scientific article published on 18 December 2018

Predicting kinase inhibitors using bioactivity matrix derived informer sets

artículo científico publicado en 2019

Predicting kinase selectivity profiles using Free-Wilson QSAR analysis

artículo científico publicado en 2008

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics

scientific article published on 14 May 2018

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

artículo científico publicado en 2015

The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.

artículo científico publicado en 2013

Three-dimensional molecular descriptors and a novel QSAR method

artículo científico publicado en 2002

Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers.

artículo científico publicado en 2016

α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer

artículo científico publicado en 2016

Lista de obras de Scott A. Wildman

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings

Approaches to virtual screening and screening library selection.

Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.

Evaluation of ligand overlap by atomic parameters

High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.

Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer

Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin

Practical Model Selection for Prospective Virtual Screening

Predicting kinase inhibitors using bioactivity matrix derived informer sets

Predicting kinase selectivity profiles using Free-Wilson QSAR analysis

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.

Three-dimensional molecular descriptors and a novel QSAR method

Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers.

α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer