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Lista de obras de David G. Standaert

A full-brain, bootstrapped analysis of diffusion tensor imaging robustly differentiates Parkinson disease from healthy controls

artículo científico publicado en 2015

A neuroprotective role for angiogenin in models of Parkinson’s disease

artículo científico publicado el 22 de diciembre de 2010

Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia

artículo científico publicado en 2005

Adenosine A2A receptor modulation of motor systems for symptomatic therapy in Parkinson's disease.

artículo científico publicado en 2003

Alpha-synuclein and chaperones in dementia with Lewy bodies.

artículo científico publicado en 2005

Alteration of striatal dopaminergic neurotransmission in a mouse model of DYT11 myoclonus-dystonia

artículo científico publicado en 2012

Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

artículo científico publicado en 2005

Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice.

artículo científico publicado en 2011

Altered responses to dopaminergic D2 receptor activation and N-type calcium currents in striatal cholinergic interneurons in a mouse model of DYT1 dystonia.

artículo científico publicado en 2006

Alternatively spliced isoforms of the NMDAR1 glutamate receptor subunit: differential expression in the basal ganglia of the rat.

artículo científico publicado en 1993

An individualized coaching program for patients with acute ischemic stroke: Feasibility study.

artículo científico publicado en 2017

Angiogenin in Parkinson disease models: role of Akt phosphorylation and evaluation of AAV-mediated angiogenin expression in MPTP treated mice

artículo científico publicado en 2013

Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro

artículo científico publicado en 2007

Are the International Parkinson disease and Movement Disorder Society progressive supranuclear palsy (IPMDS-PSP) diagnostic criteria accurate enough to differentiate common PSP phenotypes?

artículo científico publicado en 2019

Atriopeptin-immunoreactive neurons in the brain: presence in cardiovascular regulatory areas

artículo científico publicado en 1985

Biochemical Fractionation of Brain Tissue for Studies of Receptor Distribution and Trafficking

artículo científico publicado en 2008

Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials

artículo científico publicado en 2017

Biomarkers in Parkinson's disease: From pathophysiology to early diagnosis

scientific article published on 01 June 2016

Brain Alchemy: Transforming Astrocytes into Neurons for Neurodegenerative Disease

artículo científico publicado en 2020

Bridging the gaps: More inclusive research needed to fully understand Parkinson's disease

scientific article published on 11 November 2019

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease

artículo científico publicado en 2012

Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study

artículo científico publicado en 2018

Changes in the expression of the NR2B subunit during aging in macaque monkeys

artículo científico publicado en 2004

Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens

scientific article published on 12 June 2020

Child Neurology: Spastic paraparesis and dystonia with a novel ADCY5 mutation

artículo científico publicado en 2019

Cholinergic dysfunction alters synaptic integration between thalamostriatal and corticostriatal inputs in DYT1 dystonia

artículo científico publicado en 2012

Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA.

artículo científico publicado en 2012

Cholinergic regulation of striatal dopamine release: New light in dark basements

artículo científico publicado en 2016

Clinimetric Analysis of the Motor Section of the Progressive Supranuclear Palsy Rating Scale: Reliability and Factor Analysis.

artículo científico publicado en 2015

Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype

artículo científico publicado en 1997

Colocalization of atriopeptin-like immunoreactivity with choline acetyltransferase- and substance P-like immunoreactivity in the pedunculopontine and laterodorsal tegmental nuclei in the rat.

artículo científico publicado en 1986

Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation

artículo científico publicado en 2003

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study

artículo científico publicado en 2013

DNA fragmentation and immediate early gene expression in rat striatum following quinolinic acid administration

artículo científico publicado en 1995

Defining research priorities in dystonia

artículo científico publicado en 2020

Design of clinical trials of gene therapy in Parkinson disease.

artículo científico publicado en 2007

Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia

artículo científico publicado en 2011

Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents

artículo científico publicado en 2014

Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain

artículo científico publicado en 1997

Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons

artículo científico publicado en 1995

Differential expression of metabotropic glutamate receptors in the hippocampus and entorhinal cortex of the rat.

artículo científico publicado en 1994

Differential localization of the mRNAs for the pertussis toxin insensitive G-protein alpha sub-units Gq, G11, and Gz in the rat brain, and regulation of their expression after striatal deafferentation

artículo científico publicado en 1998

Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease.

artículo científico publicado en 2010

Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism

artículo científico publicado en 2008

Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?

artículo científico publicado en 2020

Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain

artículo científico publicado en 2003

Distribution of group III mGluRs in rat basal ganglia with subtype-specific antibodies

artículo científico publicado en 1999

Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain

artículo científico publicado en 1999

Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia

artículo científico publicado en 2019

Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking

scientific journal article

Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32.

artículo científico publicado en 2004

Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia.

artículo científico publicado en 2010

Dopamine release is impaired in a mouse model of DYT1 dystonia

artículo científico publicado en 2007

Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra

artículo científico publicado en 2007

Dynamic DNA Methylation Regulates Levodopa-Induced Dyskinesia

artículo científico publicado en 2016

Dysregulation of BET proteins in levodopa-induced dyskinesia.

artículo científico publicado en 2017

Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy

scholarly article

Dystonia and its disorders

artículo científico publicado en 2001

Dystonia and levodopa-induced dyskinesias in Parkinson's disease: Is there a connection?

scientific article published on 22 August 2019

Effect of Levodopa-carbidopa Intestinal Gel on Non-motor Symptoms in Patients with Advanced Parkinson's Disease

artículo científico publicado en 2017

Effects of gender on nigral gene expression and parkinson disease

artículo científico publicado en 2007

Effects of subthalamic nucleus deep brain stimulation on objective sleep outcomes in Parkinson's disease

artículo científico publicado en 2016

Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia.

artículo científico publicado en 2017

Evaluation of TorsinA as a target for Parkinson disease therapy in mouse models

artículo científico publicado en 2012

Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial.

artículo científico publicado en 2017

Evidence for oxidative stress in the subthalamic nucleus in progressive supranuclear palsy

artículo científico publicado en 1999

Exploring human-genome gut-microbiome interaction in Parkinson's disease

artículo científico publicado en 2021

Expression and activity of antioxidants in the brain in progressive supranuclear palsy

artículo científico publicado en 2002

Expression of N-methyl- d-aspartate glutamate receptor subunits in the prefrontal cortex of the rat

artículo científico publicado en 1996

Expression of N-methyl-D-aspartate receptor subunit mRNA in the human brain: mesencephalic dopaminergic neurons

artículo científico publicado en 1998

Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex

artículo científico publicado en 1998

Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus

artículo científico publicado en 1998

Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat.

artículo científico publicado en 1999

Expression of NMDA receptor subunit mRNAs in neurochemically identified projection and interneurons in the human striatum

scientific article published on 01 April 2000

Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus

artículo científico publicado en 1996

Expression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus

artículo científico publicado en 1997

Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat.

artículo científico publicado en 1998

Expression of the early-onset torsion dystonia gene (DYT1) in human brain.

artículo científico publicado en 1998

Expression of the gene for preproatriopeptin in the central nervous system of the rat

artículo científico publicado en 1988

Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.

artículo científico publicado en 2010

Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapy

artículo científico publicado en 2014

Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease.

artículo científico publicado en 2015

Frontal lobe dysfunction in progressive supranuclear palsy: evidence for oxidative stress and mitochondrial impairment

scientific article published on 01 February 2000

Function of dopamine transporter is compromised in DYT1 transgenic animal model in vivo

artículo científico publicado en 2010

Gene expression profiling in the post-mortem human brain--no cause for dismay.

artículo científico publicado en 2001

Genetic influences on cognition in progressive supranuclear palsy.

artículo científico publicado en 2017

Glucocerebrosidase, Parkinson disease, and the "senses and intellect"

artículo científico publicado en 2016

Glutamate receptor expression in rat striatum: effect of deafferentation

artículo científico

How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?

artículo científico publicado en 2016

Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons

artículo científico publicado en 1997

Huntingtin inclusions do not down-regulate specific genes in the R6/2 Huntington's disease mouse.

artículo científico publicado en 2006

Hypertension and progressive supranuclear palsy

scientific article published on 03 August 2019

Immunohistochemical localization of N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor subunits in the substantia nigra pars compacta of the rat.

artículo científico publicado en 1999

Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia

artículo científico publicado en 1998

Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia

artículo científico publicado en 1999

Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation.

artículo científico publicado en 2005

Impaired striatal D2 receptor function leads to enhanced GABA transmission in a mouse model of DYT1 dystonia.

artículo científico publicado en 2009

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.

artículo científico publicado en 2009

Implementing Levodopa-Carbidopa Intestinal Gel for Parkinson Disease: Insights from US Practitioners

scholarly article by Michelle Burack et al published 27 June 2018 in Movement disorders clinical practice

Inherited movement disorders.

artículo científico publicado en 2002

Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.

artículo científico publicado en 2016

Inhibition of the firing of vasopressin neurons by atriopeptin

artículo científico publicado en 1987

Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration

artículo científico publicado en 2009

Invisible Killers

artículo científico publicado en 2016

L-type Ca2+ channels mediate adaptation of extracellular signal-regulated kinase 1/2 phosphorylation in the ventral tegmental area after chronic amphetamine treatment

artículo científico publicado en 2004

LRRK2 inhibition attenuates microglial inflammatory responses

artículo científico publicado en 2012

LRRK2 secretion in exosomes is regulated by 14-3-3.

artículo científico publicado en 2013

Levodopa-induced dyskinesia is associated with increased thyrotropin releasing hormone in the dorsal striatum of hemi-parkinsonian rats

artículo científico publicado en 2010

Lifetime exposure to estrogen and progressive supranuclear palsy: Environmental and Genetic PSP study

artículo científico publicado en 2018

Localization of alternatively spliced NMDAR1 glutamate receptor isoforms in rat striatal neurons

artículo científico publicado en 1999

Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia

artículo científico publicado en 1999

Long-term safety and efficacy of levodopa-carbidopa intestinal gel in advanced Parkinson's disease

scientific article published on 23 March 2018

MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration

artículo científico publicado en 2013

Metabolomics and the search for biomarkers in Parkinson's disease

artículo científico publicado en 2013

Metabotropic glutamate receptors are differentially regulated during development

artículo científico publicado en 1994

Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions

artículo científico publicado en 1995

Molecular cloning and expression of rat torsinA in the normal and genetically dystonic (dt) rat.

artículo científico publicado en 2002

Molecular markers of early Parkinson's disease based on gene expression in blood

artículo científico publicado en 2007

Monitoring motor fluctuations in patients with Parkinson's disease using wearable sensors

artículo científico publicado en 2009

Monocytes and Parkinson's disease: invaders from outside?

scientific article published on 14 August 2014

Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice

artículo científico publicado en 2011

N-acetylaspartylglutamate (NAAG) protects against rat striatal quinolinic acid lesions in vivo

artículo científico publicado en 1997

NMDA receptors and nitric oxide synthase

artículo científico publicado en 1999

NMDA-R1 antisense oligodeoxynucleotides modify formalin-induced nociception and spinal c-Fos expression in rat spinal cord

artículo científico publicado en 2004

Neuroprotective therapies.

artículo científico publicado en 1999

No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain

artículo científico publicado en 2006

Novel, high-intensity exercise prescription improves muscle mass, mitochondrial function, and physical capacity in individuals with Parkinson's disease.

artículo científico publicado en 2014

Once-Weekly Subcutaneous Delivery of Polymer-Linked Rotigotine (SER-214) Provides Continuous Plasma Levels in Parkinson's Disease Patients

scientific article published on 06 April 2020

Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat.

artículo científico

Organization of atriopeptin-like immunoreactive neurons in the central nervous system of the rat.

artículo científico publicado en 1986

Pacemaker-induced tachycardia caused by inappropriate response to parkinsonian tremor

artículo científico publicado en 2005

Parkinson's disease, primates, and gene therapy: vive la différence?

artículo científico publicado en 2010

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

artículo científico publicado en 2017

Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease.

artículo científico publicado en 2017

Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's disease in vitro models.

artículo científico publicado en 2007

Progressive Supranuclear Palsy and Statin Use

scientific article published on 27 March 2020

Racial differences in Parkinson's disease medication use in the reasons for geographic and racial differences in stroke cohort: a cross-sectional study

artículo científico publicado en 2009

Rationale for and use of NMDA receptor antagonists in Parkinson's disease.

artículo científico publicado en 2004

Reaping what you sow: Cross-seeding between aggregation-prone proteins in neurodegeneration

scientific article published on 02 January 2014

Removing the blinkers: moving beyond striatal dopamine in Parkinson's disease

artículo científico publicado en 2013

Reply to letter: Suicide in Parkinson's disease patients treated with levodopa-carbidopa Intestinal Gel.

artículo científico publicado en 2015

Reply to: DUOPA® is an Excellent Alternative Treatment but with Some Caveats

scientific article published on 27 March 2019

Research goals in progressive supranuclear palsy

Research goals in progressive supranuclear palsy. First International Brainstorming Conference on PSP

scientific article published on 01 May 2000

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases

artículo científico publicado en 2019

Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.

artículo científico publicado en 2015

Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit

artículo científico publicado en 2013

SNPing SCNA regulatory elements gives a CRISPR view of genetic susceptibility in Parkinson's disease

artículo científico publicado en 2016

Scientific perspectives

artículo científico publicado en 2014

Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A(2A) adenosine receptors

artículo científico publicado en 2000

Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease

artículo científico publicado en 2016

Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease

artículo científico publicado en 2021

Simultaneous isotopic and nonisotopic in situ hybridization histochemistry with cRNA probes

artículo científico publicado en 1998

Somatic mitochondrial DNA mutations in single neurons and glia

artículo científico publicado en 2004

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

artículo científico publicado en 2002

Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat.

artículo científico publicado en 1985

Strength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia.

artículo científico publicado en 2017

Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia

artículo científico publicado en 2015

Striatal histone modifications in models of levodopa-induced dyskinesia

artículo científico publicado en 2008

Subcellular segregation of distinct heteromeric NMDA glutamate receptors in the striatum

artículo científico publicado el 1 de mayo de 2003

Systematic evaluation of levodopa-carbidopa intestinal gel patient-responder characteristics

artículo científico publicado en 2018

Target validation: the Parkinson disease perspective

artículo científico publicado en 2010

Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease

artículo científico publicado en 2008

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease

article

Ten Unsolved Questions About Neuroinflammation in Parkinson's Disease

artículo científico publicado en 2020

The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia

artículo científico publicado en 2016

The Role of Stress as a Risk Factor for Progressive Supranuclear Palsy

artículo científico publicado en 2017

The effect of unilateral subthalamic nucleus deep brain stimulation on depression in Parkinson's disease

artículo científico publicado en 2016

The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia.

artículo científico publicado en 2012

The next era of examination and management of the patient with cardiovascular disease

artículo científico publicado en 2003

The pathophysiological basis of dystonias.

artículo científico publicado en 2008

TorsinA protein and neuropathology in early onset generalized dystonia with GAG deletion

artículo científico publicado en 2003

Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures

artículo científico publicado en 2022

Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy

artículo científico publicado en 2010

Tyrosine phosphorylation of the metabotropic glutamate receptor mGluR5 in striatal neurons

artículo científico publicado en 2002

Understanding falls in progressive supranuclear palsy

artículo científico publicado en 2016

Unilateral subthalamic nucleus deep brain stimulation improves sleep quality in Parkinson's disease

artículo científico publicado en 2011

Update on the pathology of dystonia.

artículo científico publicado en 2011

VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease.

artículo científico publicado en 2009

What would Dr. James parkinson think today? Mutations in beta-glucocerebrosidase and risk of Parkinson's disease

artículo científico publicado en 2017

Widespread Tau-Specific CD4 T Cell Reactivity in the General Population

artículo científico publicado en 2019

alpha-actinin-2 in rat striatum: localization and interaction with NMDA glutamate receptor subunits

scientific article published on 01 June 2000

microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.

artículo científico publicado en 2016

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease

artículo científico publicado en 2020