Lista de obras - Stefan Barth - Dominio Público Uruguay

A CSPG4-specific immunotoxin kills rhabdomyosarcoma cells and binds to primary tumor tissues

artículo científico publicado en 2014

A Monoclonal Antibody That Discriminates Between SNAP-Tagged and CLIP-Tagged Proteins

artículo científico publicado en 2016

A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model.

artículo científico publicado en 2010

A monoclonal antibody for the detection of SNAP/CLIP-tagged proteins

artículo científico publicado en 2012

A new series of pET-derived vectors for high efficiency expression of Pseudomonas exotoxin-based fusion proteins

artículo científico publicado en 1999

A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein.

artículo científico publicado en 2016

A novel fully-human cytolytic fusion protein based on granzyme B shows in vitro cytotoxicity and ex vivo binding to solid tumors overexpressing the epidermal growth factor receptor

artículo científico publicado en 2016

A regeneration protocol for sunflower (Helianthus annuus L.) protoplasts

artículo científico publicado en 1996

A specific photoimmunotheranostics agent to detect and eliminate skin cancer cells expressing EGFR.

artículo científico publicado en 2016

Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography

artículo científico publicado en 2014

Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria

artículo científico publicado en 2016

Adoptive T-cell therapy of rhabdomyosarcoma

artículo científico publicado en 2010

An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line

artículo científico publicado en 1999

An aptamer-siRNA chimera silences the eukaryotic elongation factor 2 gene and induces apoptosis in cancers expressing αvβ3 integrin.

artículo científico publicado en 2013

Angiogenin mutants as novel effector molecules for the generation of fusion proteins with increased cytotoxic potential

artículo científico publicado en 2015

Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells

artículo científico publicado en 2004

Antimalarial activity of granzyme B and its targeted delivery by a granzyme B-single-chain Fv fusion protein.

artículo científico publicado en 2014

Applications of SNAP-tag technology in skin cancer therapy

artículo científico publicado en 2019

Assessment of the neutrophilic antibody-dependent respiratory burst (ADRB) response to Plasmodium falciparum

artículo científico publicado en 2014

Bispecific antibody-mediated destruction of Hodgkin's lymphoma cells

artículo científico publicado en 2001

CD30 as a therapeutic target for lymphoma

artículo científico publicado en 2014

CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo.

artículo científico publicado en 2016

CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases.

artículo científico publicado en 2017

CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL.

artículo científico publicado en 2017

Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.

artículo científico publicado en 2008

Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance?

artículo científico publicado en 2011

Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.

artículo científico publicado en 2016

Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites

scientific article published on 01 June 2018

Characterization of photosynthetically active duckweed (Wolffia australiana) in vitro culture by Respiration Activity Monitoring System (RAMOS)

artículo científico publicado en 2007

Cloning murine antibody V-genes with non-degenerate primers and conversion to a recombinant antibody format

artículo científico publicado en 2014

Combining phage display and screening of cDNA expression libraries: a new approach for identifying the target antigen of an scFv preselected by phage display.

artículo científico publicado en 2000

Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells.

artículo científico publicado en 2017

Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions

artículo científico publicado en 2000

Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.

artículo científico publicado en 2018

Depletion of autoreactive B-lymphocytes by a recombinant myelin oligodendrocyte glycoprotein-based immunotoxin

artículo científico publicado en 2008

Design of human granzyme B variants resistant to serpin B9

scientific article published on 31 July 2012

Designing the Sniper: Improving Targeted Human Cytolytic Fusion Proteins for Anti-Cancer Therapy via Molecular Simulation

artículo científico publicado en 2017

Detection and Specific Elimination of EGFR+ Ovarian Cancer Cells Using a Near Infrared Photoimmunotheranostic Approach

artículo científico publicado en 2017

Development of a Competitive Cystatin C-Specific Bioassay Suitable for Repetitive Measurements

artículo científico publicado en 2016

Development of novel, highly cytotoxic fusion constructs containing granzyme B: unique mechanisms and functions.

artículo científico publicado en 2009

Directed covalent immobilization of fluorescently labeled cytokines.

artículo científico publicado en 2011

Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA' and the bispecific scFv [13xds16].

artículo científico publicado en 2017

Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras

scientific article published on 09 July 2019

Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins

artículo científico publicado en 2017

Engineered human angiogenin mutations in the placental ribonuclease inhibitor complex for anticancer therapy: Insights from enhanced sampling simulations.

artículo científico publicado en 2016

EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein

artículo científico publicado en 2014

Eukaryotic expression and secretion of EGFP-labeled annexin A5.

artículo científico publicado en 2008

Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody

artículo científico publicado en 2015

Fcgamma receptor 1 (CD64), a target beyond cancer.

artículo científico publicado en 2009

Fully human MAP-fusion protein selectively targets and eliminates proliferating CD64(+) M1 macrophages

artículo científico publicado en 2016

Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins.

artículo científico

Generation of recombinant antibody fragments that target canine dendritic cells by phage display technology.

artículo científico publicado en 2010

Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes.

artículo científico publicado en 2008

Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model

artículo científico publicado en 2016

Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells

artículo científico publicado en 2013

Heat-transfer resistance measurement method (HTM)-based cell detection at trace levels using a progressive enrichment approach with highly selective cell-binding surface imprints.

artículo científico publicado en 2014

Heat-transfer-method-based cell culture quality assay through cell detection by surface imprinted polymers

artículo científico publicado en 2015

High efficiency non-viral transfection of retinal and iris pigment epithelial cells with pigment epithelium-derived factor

artículo científico publicado en 2009

Hodgkin's disease. Future treatment strategies: fact or fiction?

artículo científico publicado en 1996

Human Antibody Fusion Proteins/Antibody Drug Conjugates in Breast and Ovarian Cancer

artículo científico publicado en 2017

Human Granzyme B Based Targeted Cytolytic Fusion Proteins.

artículo científico publicado en 2018

Human MAP Tau Based Targeted Cytolytic Fusion Proteins

artículo científico publicado en 2017

Human microtubule-associated protein tau mediates targeted killing of CD30(+) lymphoma cells in vitro and inhibits tumour growth in vivo

artículo científico publicado en 2013

Immunokinases, a novel class of immunotherapeutics for targeted cancer therapy.

artículo científico publicado en 2009

Immunotoxins. Mechanism of action and applications in malignant diseases

artículo científico publicado en 1997

In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen

artículo científico publicado en 2006

In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells

artículo científico publicado en 2014

In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model

scientific article published on 26 February 2011

In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model

artículo científico publicado en 2012

Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin

artículo científico publicado en 2002

Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10.

artículo científico publicado en 2015

Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.

artículo científico publicado en 2012

Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo

artículo científico publicado en 2004

Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo

artículo científico publicado en 2013

Non-Hodgkin's Lymphoma: A Review of Immunotherapeutic Approaches to Treatment.

artículo científico publicado en 1997

Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities

artículo científico publicado en 2015

Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer

artículo científico publicado en 2017

Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo.

artículo científico publicado en 2015

Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen

artículo científico publicado en 2016

One-step site-specific antibody fragment auto-conjugation using SNAP-tag technology

scientific article published on 11 October 2019

Phage display-based generation of novel internalizing antibody fragments for immunotoxin-based treatment of acute myeloid leukemia.

artículo científico publicado en 2015

Phage display-based on-slide selection of tumor-specific antibodies on formalin-fixed paraffin-embedded human tissue biopsies.

artículo científico publicado en 2015

Photodynamic therapy mediated induction of accelerated re-endothelialisation following injury to the arterial wall: implications for the prevention of postinterventional restenosis

artículo científico publicado en 2002

Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand

artículo científico publicado en 2016

Principles of Immunotherapy: Implications for Treatment Strategies in Cancer and Infectious Diseases

scientific article published on 21 December 2018

Production and characterisation of monoclonal antibodies against RAI3 and its expression in human breast cancer

artículo científico publicado en 2009

Quantitative measurement of human anti-HCV Core immunoglobulins on an electrical biochip platform

artículo científico publicado en 2010

Quantitative molecular monitoring of residual tumor cells in chronic lymphocytic leukemia

artículo científico publicado en 2002

Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein

artículo científico publicado en 2010

Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy

artículo científico publicado en 2014

Recombinant bispecific single chain antibody fragments induce Fc gamma-receptor-mediated elimination of CD30+ lymphoma cells

artículo científico publicado en 2009

Recombinant immunotoxins--the next generation

artículo científico publicado en 2009

Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.

artículo científico publicado en 2005

Recombinant, ETA'-based CD64 immunotoxins: improved efficacy by increased valency, both in vitro and in vivo in a chronic cutaneous inflammation model in human CD64 transgenic mice

artículo científico publicado en 2010

Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage.

artículo científico publicado en 2012

Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins.

artículo científico publicado en 2017

SNAP-Tag Technology: A Promising Tool for Ex Vivo Immunophenotyping

artículo científico publicado en 2017

SNAP-Tag Technology: A Useful Tool To Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments.

artículo científico publicado en 2016

SNAP-tag based agents for preclinical in vitro imaging in malignant diseases.

artículo científico publicado en 2013

SNAP-tag technology mediates site specific conjugation of antibody fragments with a photosensitizer and improves target specific phototoxicity in tumor cells.

artículo científico publicado en 2011

Secretion of functional anti-CD30-angiogenin immunotoxins into the supernatant of transfected 293T-cells.

artículo científico publicado en 2003

Selection and enrichment of differentially labeled plant protoplasts

scientific article published on 01 July 1994

Short-chain fluorescent tryptophan tags for on-line detection of functional recombinant proteins

artículo científico publicado en 2012

Simultaneous and independent dual site-specific self-labeling of recombinant antibodies

artículo científico publicado en 2018

Site-specific, covalent labeling of recombinant antibody fragments via fusion to an engineered version of 6-O-alkylguanine DNA alkyltransferase.

artículo científico publicado en 2009

Small cleavable adapters enhance the specific cytotoxicity of a humanized immunotoxin directed against CD64-positive cells

artículo científico publicado en 2008

Systematic improvement of lentivirus transduction protocols by antibody fragments fused to VSV-G as envelope glycoprotein.

artículo científico publicado en 2014

Targeted delivery of dendritic polyglycerol-doxorubicin conjugates by scFv-SNAP fusion protein suppresses EGFR+ cancer cell growth

artículo científico publicado en 2013

Targeted ex vivo reduction of CD64-positive monocytes in chronic myelomonocytic leukemia and acute myelomonocytic leukemia using human granzyme B-based cytolytic fusion proteins.

artículo científico publicado en 2014

Targeted human cytolytic fusion proteins at the cutting edge: harnessing the apoptosis-inducing properties of human enzymes for the selective elimination of tumor cells

scientific article published on 25 January 2019

Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein

artículo científico publicado en 2015

Targeted restoration of down-regulated DAPK2 tumor suppressor activity induces apoptosis in Hodgkin lymphoma cells

artículo científico publicado en 2009

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies

artículo científico publicado en 2015

Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins.

artículo científico publicado en 2015

Targeting the fetal acetylcholine receptor in rhabdomyosarcoma.

artículo científico

The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia

artículo científico publicado en 2015

The SNAP-tag technology - a versatile tool with many applications

artículo científico publicado en 2013

The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F.

artículo científico publicado en 2016

The in vitro anti-inflammatory effects of recombinant anti-CD25 immunotoxin on lamina propria T cells of patients with inflammatory bowel disease are not sufficient to cure experimental colitis in mice

artículo científico publicado en 2002

Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells.

artículo científico publicado en 2018

Lista de obras de Stefan Barth

A CSPG4-specific immunotoxin kills rhabdomyosarcoma cells and binds to primary tumor tissues

A Monoclonal Antibody That Discriminates Between SNAP-Tagged and CLIP-Tagged Proteins

A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model.

A monoclonal antibody for the detection of SNAP/CLIP-tagged proteins

A new series of pET-derived vectors for high efficiency expression of Pseudomonas exotoxin-based fusion proteins

A novel approach for targeted elimination of CSPG4-positive triple-negative breast cancer cells using a MAP tau-based fusion protein.

A novel fully-human cytolytic fusion protein based on granzyme B shows in vitro cytotoxicity and ex vivo binding to solid tumors overexpressing the epidermal growth factor receptor

A regeneration protocol for sunflower (Helianthus annuus L.) protoplasts

A specific photoimmunotheranostics agent to detect and eliminate skin cancer cells expressing EGFR.

Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography

Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria

Adoptive T-cell therapy of rhabdomyosarcoma

An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line

An aptamer-siRNA chimera silences the eukaryotic elongation factor 2 gene and induces apoptosis in cancers expressing αvβ3 integrin.

Angiogenin mutants as novel effector molecules for the generation of fusion proteins with increased cytotoxic potential

Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells

Antimalarial activity of granzyme B and its targeted delivery by a granzyme B-single-chain Fv fusion protein.

Applications of SNAP-tag technology in skin cancer therapy

Assessment of the neutrophilic antibody-dependent respiratory burst (ADRB) response to Plasmodium falciparum

Bispecific antibody-mediated destruction of Hodgkin's lymphoma cells

CD30 as a therapeutic target for lymphoma

CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo.

CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases.

CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL.

Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2.

Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance?

Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.

Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites

Characterization of photosynthetically active duckweed (Wolffia australiana) in vitro culture by Respiration Activity Monitoring System (RAMOS)

Cloning murine antibody V-genes with non-degenerate primers and conversion to a recombinant antibody format

Combining phage display and screening of cDNA expression libraries: a new approach for identifying the target antigen of an scFv preselected by phage display.

Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells.

Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions

Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.

Depletion of autoreactive B-lymphocytes by a recombinant myelin oligodendrocyte glycoprotein-based immunotoxin

Design of human granzyme B variants resistant to serpin B9

Designing the Sniper: Improving Targeted Human Cytolytic Fusion Proteins for Anti-Cancer Therapy via Molecular Simulation

Detection and Specific Elimination of EGFR+ Ovarian Cancer Cells Using a Near Infrared Photoimmunotheranostic Approach

Development of a Competitive Cystatin C-Specific Bioassay Suitable for Repetitive Measurements

Development of novel, highly cytotoxic fusion constructs containing granzyme B: unique mechanisms and functions.

Directed covalent immobilization of fluorescently labeled cytokines.

Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA' and the bispecific scFv [13xds16].

Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras

Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins

Engineered human angiogenin mutations in the placental ribonuclease inhibitor complex for anticancer therapy: Insights from enhanced sampling simulations.

EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein

Eukaryotic expression and secretion of EGFP-labeled annexin A5.

Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody

Fcgamma receptor 1 (CD64), a target beyond cancer.

Fully human MAP-fusion protein selectively targets and eliminates proliferating CD64(+) M1 macrophages

Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins.

Generation of recombinant antibody fragments that target canine dendritic cells by phage display technology.

Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes.

Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model

Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells

Heat-transfer resistance measurement method (HTM)-based cell detection at trace levels using a progressive enrichment approach with highly selective cell-binding surface imprints.

Heat-transfer-method-based cell culture quality assay through cell detection by surface imprinted polymers

High efficiency non-viral transfection of retinal and iris pigment epithelial cells with pigment epithelium-derived factor

Hodgkin's disease. Future treatment strategies: fact or fiction?

Human Antibody Fusion Proteins/Antibody Drug Conjugates in Breast and Ovarian Cancer

Human Granzyme B Based Targeted Cytolytic Fusion Proteins.

Human MAP Tau Based Targeted Cytolytic Fusion Proteins

Human microtubule-associated protein tau mediates targeted killing of CD30(+) lymphoma cells in vitro and inhibits tumour growth in vivo

Immunokinases, a novel class of immunotherapeutics for targeted cancer therapy.

Immunotoxins. Mechanism of action and applications in malignant diseases

In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen

In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells

In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model

In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model

Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin

Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10.

Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.

Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo

Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo

Non-Hodgkin's Lymphoma: A Review of Immunotherapeutic Approaches to Treatment.

Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities

Novel PSCA targeting scFv-fusion proteins for diagnosis and immunotherapy of prostate cancer

Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo.

Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen