Lista de obras - Sreenivasan Ponnambalam - Dominio Público Uruguay

A Golgi localization signal identified in the Menkes recombinant protein

artículo científico publicado en 1998

A VE-cadherin-PAR3-α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells

artículo científico publicado en 2012

A biphasic endothelial stress-survival mechanism regulates the cellular response to vascular endothelial growth factor A.

artículo científico publicado en 2012

A combinatorial in silico and cellular approach to identify a new class of compounds that target VEGFR2 receptor tyrosine kinase activity and angiogenesis.

artículo científico publicado en 2012

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair

artículo científico publicado en 2012

A novel p53 mutant found in iatrogenic urothelial cancers is dysfunctional and can be rescued by a second-site global suppressor mutation

artículo científico publicado en 2013

ATF-2 and Tpl2 regulation of endothelial cell cycle progression and apoptosis

scientific article published on 21 November 2019

Aberrant trafficking of transmembrane proteins in human disease

artículo científico publicado en 2003

Actin and microtubule regulation of trans-Golgi network architecture, and copper-dependent protein transport to the cell surface

artículo científico publicado en 2004

Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis

artículo científico publicado en 2009

Affimer proteins are versatile and renewable affinity reagents ⬇️

artículo científico publicado en 2017

African swine fever virus causes microtubule-dependent dispersal of the trans-golgi network and slows delivery of membrane protein to the plasma membrane

artículo científico publicado en 2006

An integrative model for vascular endothelial growth factor A as a tumour biomarker

scientific article published on 20 August 2010

Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer

artículo científico publicado en 1997

Association of a phosphatidylinositol-specific 3-kinase with a human trans -Golgi network resident protein

scientific article published on 01 December 1997

Association of cPLA2-alpha and COX-1 with the Golgi apparatus of A549 human lung epithelial cells

artículo científico publicado en 2003

Atherosclerosis and the Lectin-like OXidized low-density lipoprotein scavenger receptor

artículo científico publicado en 2006

Binding of Escherichia coli RNA polymerase to a promoter carrying mutations that stop transcription initiation.

artículo científico publicado en 1987

Biochemistry and cell biology of mammalian scavenger receptors.

artículo científico publicado en 2005

Biomarkers in peripheral arterial disease

scientific article published on July 2009

Cell biology of membrane trafficking in human disease

artículo científico publicado en 2006

Chapter Eight - Ubiquitin-Mediated Regulation of Cellular Responses to Vascular Endothelial Growth Factors.

artículo científico publicado en 2016

Chromosomal location and some structural features of human clathrin light-chain genes (CLTA and CLTB)

artículo científico publicado en 1994

Clinical and Preclinical Use of LOX-1-Specific Antibodies in Diagnostics and Therapeutics

artículo científico

Constitutive protein secretion from the trans-Golgi network to the plasma membrane

artículo científico publicado en 2003

Cytosolic phospholipase A2-alpha and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus

artículo científico publicado en 2005

Cytosolic phospholipase A2-alpha mediates endothelial cell proliferation and is inactivated by association with the Golgi apparatus.

artículo científico publicado en 2005

Deciphering soluble and membrane protein function using yeast systems (Review).

artículo científico publicado en 2008

Detection and Quantification of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases in Primary Human Endothelial Cells.

artículo científico publicado en 2015

Different sorts for different sprouts.

artículo científico publicado en 2011

Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.

artículo científico publicado en 1997

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation ⬇️

artículo científico publicado en 2014

Endothelial cell confluence regulates Weibel-Palade body formation.

artículo científico publicado en 2004

Evidence for prebudding arrest of ER export in animal cell mitosis and its role in generating Golgi partitioning intermediates

artículo científico publicado en 2001

Evolution of the VEGF-Regulated Vascular Network from a Neural Guidance System

Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes ⬇️

artículo científico publicado en 2016

Forward and retrograde trafficking in mitotic animal cells. ER-Golgi transport arrest restricts protein export from the ER into COPII-coated structures.

artículo científico publicado en 1999

Functional analysis of different sequence elements in the Escherichia coli galactose operon P2 promoter

artículo científico publicado en 1988

Functional refolding of a recombinant C-type lectin-like domain containing intramolecular disulfide bonds.

artículo científico publicado en 2006

Gene therapy in the treatment of peripheral arterial disease.

artículo científico publicado en 2011

Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells.

artículo científico publicado en 2010

IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis. ⬇️

artículo científico publicado en 2018

Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation

artículo científico publicado en 2015

Identification of a di-leucine motif within the C terminus domain of the Menkes disease protein that mediates endocytosis from the plasma membrane

artículo científico publicado en 1999

In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis ⬇️

artículo científico publicado en 2014

Indolinones and anilinophthalazines differentially target VEGF-A- and basic fibroblast growth factor-mediated responses in primary human endothelial cells.

artículo científico publicado en 2012

Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.

artículo científico publicado en 2006

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels

artículo científico publicado en 2006

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

artículo científico publicado en 2006

Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.

artículo científico publicado en 2010

Lipid kinases and trans-Golgi network membrane dynamics.

artículo científico publicado en 1999

Mutations that reduce expression from the P2 promoter of the Escherichia coli galactose operon.

artículo científico publicado en 1986

Novel membrane traffic steps regulate the exocytosis of the Menkes disease ATPase

artículo científico publicado en 2002

Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation

artículo científico publicado en 2002

Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2.

artículo científico publicado en 2008

Pioglitazone-induced myofibroblast cell death: implications for cutaneous scarring ⬇️

artículo científico publicado el 1 de septiembre de 2003

Primate homologues of rat TGN38: primary structure, expression and functional implications.

artículo científico publicado en 1996

Protein secretion and the Golgi apparatus.

artículo científico publicado en 2003

Purinergic and Store-Operated Ca(2+) Signaling Mechanisms in Mesenchymal Stem Cells and Their Roles in ATP-Induced Stimulation of Cell Migration. ⬇️

artículo científico publicado en 2016

Quantifying the phosphorylation timescales of receptor-ligand complexes: a Markovian matrix-analytic approach ⬇️

artículo científico publicado en 2018

RNA polymerase molecules initiating transcription at tandem promoters can collide and cause premature transcription termination

artículo científico publicado en 1987

Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells

artículo científico publicado en 2009

Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking. ⬇️

artículo científico publicado en 2018

Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential ⬇️

artículo científico publicado en 2014

Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease

artículo científico publicado en 2020

Scavenger receptor structure and function in health and disease ⬇️

artículo científico publicado en 2015

Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease

artículo científico publicado en 2010

Schizosaccharomyces pombe ypt5: a homologue of the rab5 endosome fusion regulator

artículo científico publicado en 1993

Sorting Motifs in the Cytoplasmic Tail of the Immunomodulatory E3/49K Protein of Species D Adenoviruses Modulate Cell Surface Expression and Ectodomain Shedding ⬇️

artículo científico publicado en 2016

Sorting sweet sorting. Protein secretion.

artículo científico publicado en 1996

Stimulation-dependent recruitment of cytosolic phospholipase A2-alpha to EA.hy.926 endothelial cell membranes leads to calcium-independent association

artículo científico publicado en 2004

Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

artículo científico publicado en 2020

Studies with theEscherichia coligalactose operon regulatory region carrying a point mutation that simultaneously inactivates the two overlapping promoters Interactions with RNA polymerase and the cyclic AMP receptor protein

artículo científico publicado en 1987

TGN38 and its orthologues: roles in post-TGN vesicle formation and maintenance of TGN morphology

artículo científico publicado en 1997

Targeting signal and subcellular compartments involved in the intracellular trafficking of HLA-DMB.

artículo científico publicado en 1996

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

artículo científico publicado en 2015

The LOX-1 Scavenger Receptor and Its Implications in the Treatment of Vascular Disease

artículo científico publicado en 2012

The LOX-1 scavenger receptor cytoplasmic domain contains a transplantable endocytic motif

artículo científico publicado en 2009

The Manganese Cation Disrupts Membrane Dynamics along the Secretory Pathway

article

The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway

artículo científico publicado en 2003

The S100A6 calcium-binding protein regulates endothelial cell-cycle progression and senescence

artículo científico publicado en 2012

The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network

artículo científico publicado en 1994

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling.

artículo científico publicado en 2011

The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis ⬇️

artículo científico publicado en 2015

The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.

artículo científico publicado en 2007

The effect of ceruloplasmin on iron release from placental (BeWo) cells; evidence for an endogenous Cu oxidase.

artículo científico publicado en 2000

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

artículo científico publicado en 2008

The role of lectin-like oxidised low-density lipoprotein receptor-1 in vascular pathology

artículo científico

The trans Golgi network is lost from cells infected with African swine fever virus

artículo científico publicado en 2001

TowardIn SilicoPrediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

article

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function.

artículo científico publicado en 2019

Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent steps ⬇️

artículo científico publicado en 2013

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function ⬇️

artículo científico publicado en 2017

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration ⬇️

artículo científico publicado en 2015

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions ⬇️

artículo científico publicado en 2014

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis ⬇️

artículo científico publicado en 2016

VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis

artículo científico publicado en 2009

VEGFR1 receptor tyrosine kinase localization to the Golgi apparatus is calcium-dependent

artículo científico publicado en 2009

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8. ⬇️

artículo científico publicado en 2015

Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells. ⬇️

artículo científico publicado en 2014

Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease

artículo científico

Lista de obras de Sreenivasan Ponnambalam

A Golgi localization signal identified in the Menkes recombinant protein

A VE-cadherin-PAR3-α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells

A biphasic endothelial stress-survival mechanism regulates the cellular response to vascular endothelial growth factor A.

A combinatorial in silico and cellular approach to identify a new class of compounds that target VEGFR2 receptor tyrosine kinase activity and angiogenesis.

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair

A novel p53 mutant found in iatrogenic urothelial cancers is dysfunctional and can be rescued by a second-site global suppressor mutation

ATF-2 and Tpl2 regulation of endothelial cell cycle progression and apoptosis

Aberrant trafficking of transmembrane proteins in human disease

Actin and microtubule regulation of trans-Golgi network architecture, and copper-dependent protein transport to the cell surface

Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis

Affimer proteins are versatile and renewable affinity reagents ⬇️

African swine fever virus causes microtubule-dependent dispersal of the trans-golgi network and slows delivery of membrane protein to the plasma membrane

An integrative model for vascular endothelial growth factor A as a tumour biomarker

Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer

Association of a phosphatidylinositol-specific 3-kinase with a human trans -Golgi network resident protein

Association of cPLA2-alpha and COX-1 with the Golgi apparatus of A549 human lung epithelial cells

Atherosclerosis and the Lectin-like OXidized low-density lipoprotein scavenger receptor

Binding of Escherichia coli RNA polymerase to a promoter carrying mutations that stop transcription initiation.

Biochemistry and cell biology of mammalian scavenger receptors.

Biomarkers in peripheral arterial disease

Cell biology of membrane trafficking in human disease

Chapter Eight - Ubiquitin-Mediated Regulation of Cellular Responses to Vascular Endothelial Growth Factors.

Chromosomal location and some structural features of human clathrin light-chain genes (CLTA and CLTB)

Clinical and Preclinical Use of LOX-1-Specific Antibodies in Diagnostics and Therapeutics

Constitutive protein secretion from the trans-Golgi network to the plasma membrane

Cytosolic phospholipase A2-alpha and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus

Cytosolic phospholipase A2-alpha mediates endothelial cell proliferation and is inactivated by association with the Golgi apparatus.

Deciphering soluble and membrane protein function using yeast systems (Review).

Detection and Quantification of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases in Primary Human Endothelial Cells.

Different sorts for different sprouts.

Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation ⬇️

Endothelial cell confluence regulates Weibel-Palade body formation.

Evidence for prebudding arrest of ER export in animal cell mitosis and its role in generating Golgi partitioning intermediates

Evolution of the VEGF-Regulated Vascular Network from a Neural Guidance System

Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes ⬇️

Forward and retrograde trafficking in mitotic animal cells. ER-Golgi transport arrest restricts protein export from the ER into COPII-coated structures.

Functional analysis of different sequence elements in the Escherichia coli galactose operon P2 promoter

Functional refolding of a recombinant C-type lectin-like domain containing intramolecular disulfide bonds.

Gene therapy in the treatment of peripheral arterial disease.

Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells.

IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis. ⬇️

Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation

Identification of a di-leucine motif within the C terminus domain of the Menkes disease protein that mediates endocytosis from the plasma membrane

In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis ⬇️

Indolinones and anilinophthalazines differentially target VEGF-A- and basic fibroblast growth factor-mediated responses in primary human endothelial cells.

Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels

LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells

Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.

Lipid kinases and trans-Golgi network membrane dynamics.

Mutations that reduce expression from the P2 promoter of the Escherichia coli galactose operon.

Novel membrane traffic steps regulate the exocytosis of the Menkes disease ATPase

Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation

Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2.

Pioglitazone-induced myofibroblast cell death: implications for cutaneous scarring ⬇️

Primate homologues of rat TGN38: primary structure, expression and functional implications.

Protein secretion and the Golgi apparatus.

Purinergic and Store-Operated Ca(2+) Signaling Mechanisms in Mesenchymal Stem Cells and Their Roles in ATP-Induced Stimulation of Cell Migration. ⬇️

Quantifying the phosphorylation timescales of receptor-ligand complexes: a Markovian matrix-analytic approach ⬇️

RNA polymerase molecules initiating transcription at tandem promoters can collide and cause premature transcription termination

Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells

Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking. ⬇️

Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential ⬇️

Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease

Scavenger receptor structure and function in health and disease ⬇️

Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease

Schizosaccharomyces pombe ypt5: a homologue of the rab5 endosome fusion regulator

Sorting Motifs in the Cytoplasmic Tail of the Immunomodulatory E3/49K Protein of Species D Adenoviruses Modulate Cell Surface Expression and Ectodomain Shedding ⬇️

Sorting sweet sorting. Protein secretion.

Stimulation-dependent recruitment of cytosolic phospholipase A2-alpha to EA.hy.926 endothelial cell membranes leads to calcium-independent association

Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

Studies with theEscherichia coligalactose operon regulatory region carrying a point mutation that simultaneously inactivates the two overlapping promoters Interactions with RNA polymerase and the cyclic AMP receptor protein

TGN38 and its orthologues: roles in post-TGN vesicle formation and maintenance of TGN morphology

Targeting signal and subcellular compartments involved in the intracellular trafficking of HLA-DMB.

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

The LOX-1 Scavenger Receptor and Its Implications in the Treatment of Vascular Disease

The LOX-1 scavenger receptor cytoplasmic domain contains a transplantable endocytic motif

The Manganese Cation Disrupts Membrane Dynamics along the Secretory Pathway