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Lista de obras de Claire M Edwards

A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease.

artículo científico publicado en 2010

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

scientific article published on 26 June 2018

Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.

artículo científico publicado en 2007

Animal Models of Multiple Myeloma

scientific article published on 01 January 2019

Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase

artículo científico publicado en 2007

Apomine™, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo

artículo científico publicado en 2007

BTK inhibition in myeloma: targeting the seed and the soil

artículo científico publicado en 2012

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone

artículo científico publicado en 2016

Bone marrow adiposity and multiple myeloma.

artículo científico publicado en 2018

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.

artículo científico publicado en 2012

Contributions of the Bone Microenvironment to Monoclonal Gammopathy of Undetermined Significance Pathogenesis

scientific article published on 01 December 2018

Contributions of the host microenvironment to cancer-induced bone disease.

artículo científico publicado en 2014

Diet-induced obesity promotes a myeloma-like condition in vivo

scientific article published on 07 October 2014

LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis

artículo científico publicado en 2006

Metformin and Prostate Cancer: a New Role for an Old Drug.

artículo científico publicado en 2017

Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data

scientific article published on 23 March 2020

Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment

scientific article published on 02 October 2019

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha

artículo científico publicado en 2019

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.

artículo científico publicado en 2009

New approaches to targeting the bone marrow microenvironment in multiple myeloma

artículo científico publicado en 2016

Novel therapeutic targets in myeloma bone disease

artículo científico publicado en 2014

Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells

artículo científico publicado el 16 de noviembre de 2012

Preclinical animal models of multiple myeloma

artículo científico publicado en 2016

Selective targeting of death receptor 5 circumvents resistance of MG-63 osteosarcoma cells to TRAIL-induced apoptosis.

artículo científico publicado en 2007

Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp)

scientific article published on 26 August 2019

The Role of the Microenvironment in Prostate Cancer-Associated Bone Disease

artículo científico publicado en 2016

The pathogenesis of the bone disease of multiple myeloma.

artículo científico publicado en 2008

The role of bone marrow adipocytes in bone metastasis

scientific article published on 08 April 2016

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

artículo científico publicado en 2019

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer.

artículo científico publicado en 2016