Lista de obras - Giulio Cossu - Dominio Público Uruguay

'Hearts and bones': the ups and downs of 'plasticity' in stem cell biology.

artículo científico publicado en 2012

A discussion on cell therapy in Manchester

artículo científico publicado en 2016

A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene

artículo científico publicado en 2009

Alpha sarcoglycan is required for FGF-dependent myogenic progenitor cell proliferation in vitro and in vivo

artículo científico publicado en 2011

An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis ⬇️

artículo científico publicado el 7 de enero de 2011

Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy

artículo científico publicado en 2014

Bystander effect on brain tissue of mesoangioblasts producing neurotrophins

artículo científico publicado en 2012

Challenges in translational research

artículo científico publicado en 2009

Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European Union.

artículo científico

Collagen VI regulates satellite cell self-renewal and muscle regeneration.

artículo científico publicado en 2013

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin

artículo científico publicado en 2012

Disruptive influence.

artículo científico publicado en 2013

Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory

artículo científico publicado en 2013

Globular adiponectin as a complete mesoangioblast regulator: role in proliferation, survival, motility, and skeletal muscle differentiation.

artículo científico publicado en 2010

Hemogenic endothelium generates mesoangioblasts that contribute to several mesodermal lineages in vivo

artículo científico publicado en 2014

Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts

artículo científico publicado en 2010

Hmgb3 is regulated by microRNA-206 during muscle regeneration

artículo científico publicado en 2012

Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells

artículo científico publicado en 2009

Human cardiac mesoangioblasts isolated from hypertrophic cardiomyopathies are greatly reduced in proliferation and differentiation potency.

artículo científico publicado en 2009

Human iPSC-derived mesoangioblasts, like their tissue-derived counterparts, suppress T cell proliferation through IDO- and PGE-2-dependent pathways.

artículo científico publicado en 2013

In vivo generation of a mature and functional artificial skeletal muscle

artículo científico publicado en 2015

Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo

artículo científico publicado en 2009

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD

artículo científico publicado en 2014

Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways

artículo científico publicado en 2009

Injectable polyethylene glycol-fibrinogen hydrogel adjuvant improves survival and differentiation of transplanted mesoangioblasts in acute and chronic skeletal-muscle degeneration.

artículo científico publicado en 2012

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

artículo científico publicado en 2015

Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs

artículo científico publicado en 2011

Isolation, Characterization and Differentiation Potential of Cardiac Progenitor Cells in Adult Pigs

artículo científico publicado en 2012

L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts

artículo científico publicado en 2011

Mesoangioblasts suppress T cell proliferation through IDO and PGE-2-dependent pathways

artículo científico publicado en 2012

Necdin enhances muscle reconstitution of dystrophic muscle by vessel-associated progenitors, by promoting cell survival and myogenic differentiation

artículo científico publicado en 2011

New ISSCR guidelines underscore major principles for responsible translational stem cell research

artículo científico publicado en 2008

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle

artículo científico publicado en 2016

Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression

artículo científico publicado en 2016

Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation

artículo científico publicado en 2010

No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels

artículo científico publicado en 2016

Noggin recruits mesoderm progenitors from the dorsal aorta to a skeletal myogenic fate

artículo científico publicado en 2012

OP-1 ARTIFICIAL OESOPHAGUS ENGINEERING IN A 3D DYNAMIC CULTURE.

artículo científico publicado en 2015

Out of the niche: exploring unknown pathways

artículo científico publicado en 2014

PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence

artículo científico publicado en 2015

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.

artículo científico publicado en 2010

Pericyte-fibroblast transition promotes tumor growth and metastasis.

artículo científico publicado en 2016

Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells

artículo científico publicado en 2011

Quantitative muscle strength assessment in duchenne muscular dystrophy: longitudinal study and correlation with functional measures

artículo científico publicado en 2012

Regulatory evaluation of Glybera in Europe - two committees, one mission

artículo científico publicado en 2013

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells

artículo científico publicado en 2010

Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.

artículo científico publicado en 2012

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.

artículo científico publicado en 2017

Skeletal Muscle Differentiation of Embryonic Mesoangioblasts Requires Pax3 Activity

artículo científico publicado en 2009

Skeletal Muscle Differentiation on a Chip Shows Human Donor Mesoangioblasts' Efficiency in Restoring Dystrophin in a Duchenne Muscular Dystrophy Model

artículo científico publicado en 2016

Sox2 transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts

artículo científico publicado en 2010

Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6

artículo científico publicado en 2011

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.

artículo científico publicado en 2011

TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors

scientific article published on 08 August 2019

Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles.

artículo científico publicado en 2013

The committee for advanced therapies' of the European Medicines Agency reflection paper on management of clinical risks deriving from insertional mutagenesis

artículo científico publicado en 2013

The increase of pericyte population in human neuromuscular disorders supports their role in muscle regeneration in vivo

artículo científico publicado en 2012

The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoA

artículo científico publicado en 2009

The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7.

artículo científico publicado en 2009

Transgelin expressing myofibroblasts orchestrate ventral midline closure through TGF-β signalling

artículo científico

Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming

artículo científico publicado en 2017

Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.

artículo científico publicado en 2012

Transplanted mesoangioblasts require macrophage IL-10 for survival in a mouse model of muscle injury.

artículo científico publicado en 2012

c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging

scientific journal article

miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors

scientific journal article

Lista de obras de Giulio Cossu

'Hearts and bones': the ups and downs of 'plasticity' in stem cell biology.

A discussion on cell therapy in Manchester

A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene

Alpha sarcoglycan is required for FGF-dependent myogenic progenitor cell proliferation in vitro and in vivo

An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis ⬇️

Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy

Bystander effect on brain tissue of mesoangioblasts producing neurotrophins

Challenges in translational research

Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European Union.

Collagen VI regulates satellite cell self-renewal and muscle regeneration.

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin

Disruptive influence.

Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory

Globular adiponectin as a complete mesoangioblast regulator: role in proliferation, survival, motility, and skeletal muscle differentiation.

Hemogenic endothelium generates mesoangioblasts that contribute to several mesodermal lineages in vivo

Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts

Hmgb3 is regulated by microRNA-206 during muscle regeneration

Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells

Human cardiac mesoangioblasts isolated from hypertrophic cardiomyopathies are greatly reduced in proliferation and differentiation potency.

Human iPSC-derived mesoangioblasts, like their tissue-derived counterparts, suppress T cell proliferation through IDO- and PGE-2-dependent pathways.

In vivo generation of a mature and functional artificial skeletal muscle

Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo

Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD

Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways

Injectable polyethylene glycol-fibrinogen hydrogel adjuvant improves survival and differentiation of transplanted mesoangioblasts in acute and chronic skeletal-muscle degeneration.

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs

Isolation, Characterization and Differentiation Potential of Cardiac Progenitor Cells in Adult Pigs

L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts

Mesoangioblasts suppress T cell proliferation through IDO and PGE-2-dependent pathways

Necdin enhances muscle reconstitution of dystrophic muscle by vessel-associated progenitors, by promoting cell survival and myogenic differentiation

New ISSCR guidelines underscore major principles for responsible translational stem cell research

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle

Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression

Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation

No Identical "Mesenchymal Stem Cells" at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels

Noggin recruits mesoderm progenitors from the dorsal aorta to a skeletal myogenic fate

OP-1 ARTIFICIAL OESOPHAGUS ENGINEERING IN A 3D DYNAMIC CULTURE.

Out of the niche: exploring unknown pathways

PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence

Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.

Pericyte-fibroblast transition promotes tumor growth and metastasis.

Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells

Quantitative muscle strength assessment in duchenne muscular dystrophy: longitudinal study and correlation with functional measures

Regulatory evaluation of Glybera in Europe - two committees, one mission

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells

Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.

Skeletal Muscle Differentiation of Embryonic Mesoangioblasts Requires Pax3 Activity

Skeletal Muscle Differentiation on a Chip Shows Human Donor Mesoangioblasts' Efficiency in Restoring Dystrophin in a Duchenne Muscular Dystrophy Model

Sox2 transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts

Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.

TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors

Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles.

The committee for advanced therapies' of the European Medicines Agency reflection paper on management of clinical risks deriving from insertional mutagenesis

The increase of pericyte population in human neuromuscular disorders supports their role in muscle regeneration in vivo

The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoA

The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7.

Transgelin expressing myofibroblasts orchestrate ventral midline closure through TGF-β signalling

Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming

Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.

Transplanted mesoangioblasts require macrophage IL-10 for survival in a mouse model of muscle injury.

c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging

miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors