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Lista de obras de Michiel J van Esdonk

A Novel Somatostatin-Dopamine Chimera (BIM23B065) Reduced Growth Hormone Secretion In A First-in-human Clinical Trial

scientific article published on 01 March 2019

A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds

artículo científico publicado en 2017

Comprehensive evaluation of microneedle-based intradermal adalimumab delivery versus subcutaneous administration: results of a randomized controlled trial

scientific article published on 05 January 2021

Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data

artículo científico publicado en 2022

First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma

artículo científico publicado en 2020

How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.

artículo científico publicado en 2018

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy

artículo científico publicado en 2016

Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone

artículo científico publicado en 2020

Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: An exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis

scientific article published on 03 January 2020

Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement

scientific article published in 2021

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

artículo científico publicado en 2018

Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability

article

Prediction of glycaemic control in young children and adolescents with type 1 diabetes mellitus using mixed-effects logistic regression modelling.

artículo científico publicado en 2017

Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling

scientific article published on 04 April 2020

The Oral Pheneticillin Absorption Test: An Accurate Method to Identify Patients with Inadequate Oral Pheneticillin Absorption

artículo científico publicado en 2019