Lista de obras - Lars Zender - Dominio Público Uruguay

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

artículo científico publicado en 2017

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

artículo científico publicado en 2012

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

artículo científico publicado en 2013

A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

scientific journal article

A microRNA component of the p53 tumour suppressor network

artículo científico publicado en 2007

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer

artículo científico publicado en 2012

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

artículo científico publicado en 2008

C-arm computed tomography parenchymal blood volume measurement in evaluation of hepatocellular carcinoma before transarterial chemoembolization with drug eluting beads

artículo científico publicado en 2015

Caspase 8 small interfering RNA prevents acute liver failure in mice

artículo científico publicado en 2003

Combination of repeated single-session percutaneous ethanol injection and transarterial chemoembolisation compared to repeated single-session percutaneous ethanol injection in patients with non-resectable hepatocellular carcinoma

artículo científico publicado en 2006

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

artículo científico publicado en 2008

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

artículo científico publicado en 2012

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo

artículo científico publicado en 2006

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

artículo científico publicado en 2016

Doxycycline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells

artículo científico publicado en 2004

EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

artículo científico publicado en 2014

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model

artículo científico publicado en 2009

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

artículo científico publicado en 2008

IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models

artículo científico publicado en 2016

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

artículo científico publicado en 2006

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening ⬇️

artículo científico publicado el 8 de marzo de 2011

Immune surveillance of pre-cancerous senescent hepatocytes limits hepatocellular carcinoma development

artículo científico publicado en 2012

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies ⬇️

artículo científico publicado el 2 de abril de 2012

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

artículo científico publicado en 2012

Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver

artículo científico publicado en 2005

Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice

artículo científico publicado en 2015

Integrative analyses for omics data: a Bayesian mixture model to assess the concordance of ChIP-chip and ChIP-seq measurements

artículo científico publicado en 2012

Integrative oncogenomic approaches for accelerated cancer-gene discovery

artículo científico publicado en 2008

Keeping your senescent cells under control

artículo científico publicado en 2009

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

artículo científico publicado en 2017

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression

artículo científico publicado en 2009

Molecular pathogenesis and targeted therapy of hepatocellular carcinoma

artículo científico publicado en 2008

Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens

artículo científico publicado en 2006

NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis.

artículo científico publicado en 2005

Protein transduction domains fused to virus receptors improve cellular virus uptake and enhance oncolysis by tumor-specific replicating vectors

artículo científico publicado en 2004

Reciprocal interaction of Wnt and RXR-α pathways in hepatocyte development and hepatocellular carcinoma

artículo científico publicado en 2015

Reconstitution of Mice with Modified Liver Stem Cells

artículo científico publicado en 2015

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

artículo científico publicado en 2013

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

artículo científico publicado en 2016

Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity

artículo científico publicado en 2010

Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

artículo científico publicado en 2004

Snapshot: genetic mouse models of cancer

artículo científico publicado en 2007

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development

artículo científico publicado en 2014

Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues

artículo científico publicado en 2009

Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.

artículo científico publicado en 2005

The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation

artículo científico publicado en 2011

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

artículo científico publicado en 2017

Tissue-specific and reversible RNA interference in transgenic mice

artículo científico publicado en 2007

Transarterial chemoembolization using degradable starch microspheres and iodized oil in the treatment of advanced hepatocellular carcinoma: evaluation of tumor response, toxicity, and survival.

artículo científico publicado en 2007

Tumor-specific adenoviral gene therapy: transcriptional repression of gene expression by utilizing p53-signal transduction pathways

artículo científico publicado en 2004

Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice ⬇️

artículo científico publicado el 6 de junio de 2011

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

artículo científico publicado en 2009

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

artículo científico publicado en 2015

p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication

artículo científico publicado en 2009

Lista de obras de Lars Zender

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

A microRNA component of the p53 tumour suppressor network

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

C-arm computed tomography parenchymal blood volume measurement in evaluation of hepatocellular carcinoma before transarterial chemoembolization with drug eluting beads

Caspase 8 small interfering RNA prevents acute liver failure in mice

Combination of repeated single-session percutaneous ethanol injection and transarterial chemoembolisation compared to repeated single-session percutaneous ethanol injection in patients with non-resectable hepatocellular carcinoma

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

Doxycycline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells

EEF1A2 inactivates p53 by way of PI3K/AKT/mTOR-dependent stabilization of MDM4 in hepatocellular carcinoma

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening ⬇️

Immune surveillance of pre-cancerous senescent hepatocytes limits hepatocellular carcinoma development

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies ⬇️

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver

Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice

Integrative analyses for omics data: a Bayesian mixture model to assess the concordance of ChIP-chip and ChIP-seq measurements

Integrative oncogenomic approaches for accelerated cancer-gene discovery

Keeping your senescent cells under control

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression

Molecular pathogenesis and targeted therapy of hepatocellular carcinoma

Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens

NFkappaB-mediated upregulation of bcl-xl restrains TRAIL-mediated apoptosis in murine viral hepatitis.

Protein transduction domains fused to virus receptors improve cellular virus uptake and enhance oncolysis by tumor-specific replicating vectors

Reciprocal interaction of Wnt and RXR-α pathways in hepatocyte development and hepatocellular carcinoma

Reconstitution of Mice with Modified Liver Stem Cells

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity

Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

Snapshot: genetic mouse models of cancer

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development

Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues

Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.

The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

Tissue-specific and reversible RNA interference in transgenic mice

Transarterial chemoembolization using degradable starch microspheres and iodized oil in the treatment of advanced hepatocellular carcinoma: evaluation of tumor response, toxicity, and survival.

Tumor-specific adenoviral gene therapy: transcriptional repression of gene expression by utilizing p53-signal transduction pathways

Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice ⬇️

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication