Lista de obras - Gisli Jenkins - Dominio Público Uruguay

A big beautiful wall against infection

artículo científico publicado en 2017

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

artículo científico publicado en 2014

A systematic review of Anakinra, Tocilizumab, Sarilumab and Siltuximab for coronavirus-related infections

scientific article published on 27 April 2020

Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.

artículo científico publicado en 2016

Adjustment for index event bias in genome-wide association studies of subsequent events

article

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

artículo científico publicado en 2016

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

artículo científico publicado en 2016

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

artículo científico publicado en 2017

An integrin-targeted non-viral vector for pulmonary gene therapy

artículo científico publicado en 2000

Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation

artículo científico publicado en 2014

Biophysical characterization of an integrin-targeted non-viral vector

artículo científico publicado en 2003

Bronchoalveolar Lavage is Safe and Well Tolerated in Individuals with Idiopathic Pulmonary Fibrosis: An Analysis of the PROFILE Study

artículo científico publicado en 2020

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

artículo científico publicado en 2016

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

artículo científico publicado en 2021

Climate change and lung health: presidential failure, professional responsibility

scientific article published on 21 April 2019

Climate change and lung health: the challenge for a new president

artículo científico publicado en 2017

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

artículo científico publicado en 2001

Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.

artículo científico publicado en 2002

Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis

artículo científico publicado en 2024

ECM Crosslinking Enhances Fibroblast Growth and Protects Against Matrix Proteolysis in Lung Fibrosis.

artículo científico publicado en 2017

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

artículo científico publicado en 2004

Embracing social media

artículo científico publicado en 2015

Endotyping idiopathic pulmonary fibrosis should improve outcomes for all patients with progressive fibrotic lung disease

artículo científico publicado en 2014

First year of the thoracic triumvirate

artículo científico publicado en 2016

Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo

artículo científico publicado en 2003

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

artículo científico publicado en 2017

IPF: Moving from Idiopathic to Infectious Pulmonary Fibrosis?

artículo científico publicado en 2017

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis

artículo científico publicado en 2021

In search of the fibrotic epithelial cell: opportunities for a collaborative network.

artículo científico publicado en 2011

Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation

artículo científico publicado en 2014

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma

artículo científico publicado en 2011

Interplay Between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2017

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

artículo científico publicado en 2015

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

artículo científico publicado en 2006

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

artículo científico publicado en 2015

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema

artículo científico publicado en 2016

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

artículo científico publicado en 2009

Mapping the future for pulmonary fibrosis: report from the 17th International Colloquium on Lung and Airway Fibrosis

artículo científico publicado en 2013

Methods for the Assessment of Active Transforming Growth Factor-β in Cells and Tissues.

artículo científico publicado en 2017

Molecular Endotyping of Pulmonary Fibrosis

artículo científico

Novel approaches to pulmonary fibrosis

artículo científico publicado en 2014

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study

scientific article published on 02 October 2020

Pirfenidone should be prescribed for patients with idiopathic pulmonary fibrosis

scientific article published on 05 March 2013

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis

artículo científico publicado en 2013

Preprint servers: a 'rush to publish' or 'just in time delivery' for science?

artículo científico publicado en 2020

Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case-control study.

artículo científico publicado en 2013

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations

artículo científico publicado en 2020

Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land?

artículo científico publicado el 1 de enero de 2003

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

artículo científico publicado en 2016

Reducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis.

artículo científico publicado en 2015

Reply to: Hospitalization Outcomes for COVID-19 in Patients with Interstitial Lung Disease; a Potential Role for Aerodigestive Pathophysiology?

scientific article published on 20 November 2020

Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis

artículo científico publicado en 2010

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study

artículo científico publicado en 2023

Respiratory follow-up of patients with COVID-19 pneumonia

artículo científico publicado en 2020

Review of the British Thoracic Society Winter Meeting 2016, 7-9 December, London, UK.

artículo científico publicado en 2017

Review of the British Thoracic Society Winter Meeting 2017, 6-8 December 2017, London, UK

scientific article published on 14 June 2018

Review of the British Thoracic Society Winter Meeting 2018, 5-7 December 2018, London, UK

artículo científico publicado en 2019

Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis

artículo científico publicado en 2009

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

artículo científico publicado en 2016

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

artículo científico publicado en 2004

Sphingosine-1-phosphate metabolism: can its enigmatic lyase promote the autophagy of fibrosis?

artículo científico publicado en 2015

Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis

artículo científico publicado en 2016

Study the past to divine the future. Confucius' wisdom doesn't work for idiopathic pulmonary fibrosis

artículo científico publicado en 2016

TGF-β Activation and Lung Fibrosis

artículo científico publicado en 2012

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.

artículo científico publicado en 2016

The British Thoracic Society survey of rehabilitation to support recovery of the Post Covid -19 population.

artículo científico publicado en 2020

The first thoracic triumvirate

artículo científico publicado en 2015

The pathogenesis of idiopathic pulmonary fibrosis.

artículo científico publicado en 2010

The rising incidence of idiopathic pulmonary fibrosis in the U.K

artículo científico publicado en 2011

To Suppress the Radicals We Must Have Biomarkers of Oxidative Stress

artículo científico publicado en 2016

Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response ⬇️

artículo científico publicado el 6 de septiembre de 2012

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

scientific article published on 16 September 2020

Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

artículo científico publicado en 2008

αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease

artículo científico publicado en 2015

Lista de obras de Gisli Jenkins

A big beautiful wall against infection

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

A systematic review of Anakinra, Tocilizumab, Sarilumab and Siltuximab for coronavirus-related infections

Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.

Adjustment for index event bias in genome-wide association studies of subsequent events

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

An integrin-targeted non-viral vector for pulmonary gene therapy

Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation

Biophysical characterization of an integrin-targeted non-viral vector

Bronchoalveolar Lavage is Safe and Well Tolerated in Individuals with Idiopathic Pulmonary Fibrosis: An Analysis of the PROFILE Study

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

Climate change and lung health: presidential failure, professional responsibility

Climate change and lung health: the challenge for a new president

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.

Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis

ECM Crosslinking Enhances Fibroblast Growth and Protects Against Matrix Proteolysis in Lung Fibrosis.

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

Embracing social media

Endotyping idiopathic pulmonary fibrosis should improve outcomes for all patients with progressive fibrotic lung disease

First year of the thoracic triumvirate

Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

IPF: Moving from Idiopathic to Infectious Pulmonary Fibrosis?

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis

In search of the fibrotic epithelial cell: opportunities for a collaborative network.

Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma

Interplay Between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

Mapping the future for pulmonary fibrosis: report from the 17th International Colloquium on Lung and Airway Fibrosis

Methods for the Assessment of Active Transforming Growth Factor-β in Cells and Tissues.

Molecular Endotyping of Pulmonary Fibrosis

Novel approaches to pulmonary fibrosis

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study

Pirfenidone should be prescribed for patients with idiopathic pulmonary fibrosis

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis

Preprint servers: a 'rush to publish' or 'just in time delivery' for science?

Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case-control study.

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations

Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land?

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

Reducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis.

Reply to: Hospitalization Outcomes for COVID-19 in Patients with Interstitial Lung Disease; a Potential Role for Aerodigestive Pathophysiology?

Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study

Respiratory follow-up of patients with COVID-19 pneumonia

Review of the British Thoracic Society Winter Meeting 2016, 7-9 December, London, UK.

Review of the British Thoracic Society Winter Meeting 2017, 6-8 December 2017, London, UK

Review of the British Thoracic Society Winter Meeting 2018, 5-7 December 2018, London, UK

Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

Sphingosine-1-phosphate metabolism: can its enigmatic lyase promote the autophagy of fibrosis?

Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis

Study the past to divine the future. Confucius' wisdom doesn't work for idiopathic pulmonary fibrosis

TGF-β Activation and Lung Fibrosis

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.

The British Thoracic Society survey of rehabilitation to support recovery of the Post Covid -19 population.

The first thoracic triumvirate

The pathogenesis of idiopathic pulmonary fibrosis.

The rising incidence of idiopathic pulmonary fibrosis in the U.K

To Suppress the Radicals We Must Have Biomarkers of Oxidative Stress

Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response ⬇️

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease