Lista de obras - Manuela Battaglia - Dominio Público Uruguay

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome

artículo científico publicado en 2007

Abnormalities of the Exocrine Pancreas in Type 1 Diabetes

artículo científico publicado en 2015

All in (IL-) 1?

artículo científico publicado en 2015

Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant

artículo científico publicado en 2009

Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy?

artículo científico publicado en 2009

CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice

artículo científico publicado en 2014

Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial

artículo científico publicado en 2014

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice

artículo científico publicado en 2010

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.

artículo científico publicado en 2015

Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice

artículo científico publicado en 2015

Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene

artículo científico publicado en 2009

Concise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 Diabetes

artículo científico publicado en 2016

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

artículo científico publicado en 2010

Evidence for preferred MHC class II-TCR recognition independent of the source of bound peptide

scientific article published on 01 August 2002

Expanding human T regulatory cells with the mTOR-inhibitor rapamycin

artículo científico publicado en 2012

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

artículo científico publicado en 2011

Experiments by nature: lessons on type 1 diabetes.

artículo científico

Generation of Donor-specific T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation

artículo científico publicado en 2015

Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation

artículo científico publicado en 2015

Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.

artículo científico publicado en 2002

Hurdles in therapy with regulatory T cells

artículo científico

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo

artículo científico publicado en 2016

Immune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD Mice

artículo científico publicado en 2015

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice

artículo científico publicado en 2009

Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes.

artículo científico

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

artículo científico publicado en 2006

Induction of transplantation tolerance via regulatory T cells.

artículo científico publicado en 2006

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

artículo científico publicado en 2006

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

artículo científico publicado en 2019

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

artículo científico publicado en 2018

Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.

artículo científico publicado en 2015

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

artículo científico publicado en 2017

Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes

artículo científico publicado en 2010

Neutrophils and type 1 autoimmune diabetes

artículo científico

Neutrophils and type 1 diabetes: current knowledge and suggested future directions

artículo científico publicado en 2019

Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove

artículo científico publicado en 2002

PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.

artículo científico publicado en 2014

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.

artículo científico publicado en 2011

Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.

artículo científico publicado en 2006

Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation

artículo científico publicado en 2011

Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.

artículo científico publicado en 2010

Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

artículo científico publicado en 2008

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

artículo científico publicado en 2005

Reduction of circulating neutrophils precedes and accompanies type 1 diabetes

artículo científico publicado en 2013

Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.

artículo científico publicado en 2005

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.

artículo científico publicado en 2007

Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: implication for mouse model

artículo científico publicado en 2007

Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity.

artículo científico publicado en 2013

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

artículo científico publicado en 2008

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

artículo científico publicado en 2014

Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

artículo científico publicado en 2011

Standardization in flow cytometry: correct sample handling as a priority

artículo científico publicado en 2012

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

artículo científico publicado en 2003

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

artículo científico publicado en 2011

The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases

artículo científico publicado en 2018

The Tregs' world according to GARP.

artículo científico publicado en 2009

The fate of human Treg cells.

artículo científico publicado en 2009

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

artículo científico publicado en 2007

The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization

artículo científico publicado en 2014

The puzzling world of murine T regulatory cells.

artículo científico publicado en 2002

The role of interleukin 10 in the control of autoimmunity.

artículo científico publicado en 2003

The streetlight effect in type 1 diabetes

artículo científico publicado en 2015

Towards an Earlier and Timely Diagnosis of Type 1 Diabetes: Is it Time to Change Criteria to Define Disease Onset?

artículo científico

Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications.

artículo científico publicado en 2014

Tr1 cells: from discovery to their clinical application.

artículo científico publicado en 2006

Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen

artículo científico publicado en 2013

Type 1 regulatory T (Tr1) cells: from the bench to the bedside

artículo científico publicado en 2012

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

artículo científico publicado en 2007

Lista de obras de Manuela Battaglia

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome

Abnormalities of the Exocrine Pancreas in Type 1 Diabetes

All in (IL-) 1?

Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant

Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy?

CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice

Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.

Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice

Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene

Concise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 Diabetes

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

Evidence for preferred MHC class II-TCR recognition independent of the source of bound peptide

Expanding human T regulatory cells with the mTOR-inhibitor rapamycin

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

Experiments by nature: lessons on type 1 diabetes.

Generation of Donor-specific T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation

Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation

Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.

Hurdles in therapy with regulatory T cells

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo

Immune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD Mice

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice

Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes.

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

Induction of transplantation tolerance via regulatory T cells.

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes

Neutrophils and type 1 autoimmune diabetes

Neutrophils and type 1 diabetes: current knowledge and suggested future directions

Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove

PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.

Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.

Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation

Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.

Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

Reduction of circulating neutrophils precedes and accompanies type 1 diabetes

Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.

Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: implication for mouse model

Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity.

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors.

Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

Standardization in flow cytometry: correct sample handling as a priority

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner

The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases

The Tregs' world according to GARP.

The fate of human Treg cells.

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization

The puzzling world of murine T regulatory cells.

The role of interleukin 10 in the control of autoimmunity.

The streetlight effect in type 1 diabetes

Towards an Earlier and Timely Diagnosis of Type 1 Diabetes: Is it Time to Change Criteria to Define Disease Onset?

Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications.

Tr1 cells: from discovery to their clinical application.

Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen

Type 1 regulatory T (Tr1) cells: from the bench to the bedside

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells