Lista de obras - Kaylene J. Simpson - Dominio Público Uruguay

A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens

artículo científico publicado en 2018

A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4.

artículo científico publicado en 2017

A Phenotypic High-Content Screening Assay to Identify Regulators of Membrane Protein Localization

artículo científico publicado en 2016

A functional genetic screen defines the AKT-induced senescence signaling network

scientific article published on 08 July 2019

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage.

scientific article published on 24 January 2014

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

artículo científico publicado en 2013

A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.

artículo científico publicado en 2016

A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer

article

A high-throughput, multiplex cell death assay using an RNAi screening approach

artículo científico publicado en 2014

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death

artículo científico publicado en 2020

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

artículo científico publicado en 2016

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

artículo científico publicado en 2010

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species

artículo científico publicado en 2017

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species.

artículo científico publicado en 2017

Brca1 inactivation induces p27(Kip1)-dependent cell cycle arrest and delayed development in the mouse mammary gland.

artículo científico publicado en 2004

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

artículo científico publicado en 2019

Colloquium: SBI(2) HCS/HCA Informatics and Data Analysis--Best Practices and Unmet Needs September 15, 2015.

artículo científico publicado en 2015

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence.

artículo científico publicado en 2016

Comparative high-throughput RNAi screening methodologies in C. elegans and mammalian cells.

artículo científico publicado en 2012

Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.

artículo científico publicado en 2016

Developmentally-regulated expression of a putative protease inhibitor gene in the lactating mammary gland of the tammar wallaby, Macropus eugenii

artículo científico publicado en 1998

Differential expression of the whey acidic protein gene during lactation in the brushtail possum (Trichosurus vulpecula).

artículo científico publicado en 2001

Discovering cancer vulnerabilities using high-throughput micro-RNA screening

artículo científico publicado en 2017

Dual microRNA Screens Reveal That the Immune-Responsive miR-181 Promotes Henipavirus Entry and Cell-Cell Fusion.

artículo científico publicado en 2016

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition

artículo científico publicado en 2015

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

artículo científico publicado en 2022

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

article

FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases.

artículo científico publicado en 2009

Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer

artículo científico publicado en 2013

Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma

artículo científico publicado en 2004

Functional genomics down under: RNAi screening in the Victorian Centre for Functional Genomics

artículo científico

Generation of a functional mammary gland from a single stem cell

artículo científico publicado en 2006

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

artículo científico publicado en 2017

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

artículo científico publicado en 2014

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

artículo científico publicado en 2016

High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

artículo científico publicado en 2021

High-content assay for measuring intracellular growth of Leishmania in human macrophages

artículo científico publicado en 2015

High-throughput approaches to measuring cell death

artículo científico publicado en 2014

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

scientific article published on 26 March 2018

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

artículo científico publicado en 2008

Knocking down the obstacles to functional genomics data sharing

artículo científico publicado en 2017

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development.

artículo científico publicado en 2004

Maternal regulation of milk composition, milk production, and pouch young development during lactation in the tammar wallaby (Macropus eugenii ).

artículo científico publicado en 2003

Metabolic profiling and in vitro assessment of anthelmintic fractions of Picria fel-terrae Lour

artículo científico publicado en 2016

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

artículo científico publicado en 2020

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer.

artículo científico publicado en 2018

Molecular characterisation and hormone-dependent expression of the porcine whey acidic protein gene

artículo científico publicado en 1998

Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens

artículo científico publicado en 2012

Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

artículo científico publicado en 2016

Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR.

artículo científico publicado en 2008

Psidin, a conserved protein that regulates protrusion dynamics and cell migration

artículo científico publicado en 2011

Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma

artículo científico publicado en 2006

Regulation of cell adhesion and collective cell migration by hindsight and its human homolog RREB1

artículo científico publicado en 2008

SBI2 HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium.

artículo científico publicado en 2017

Screening of the 'Stasis Box' identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus.

artículo científico publicado en 2017

Society of Biomolecular Imaging and Informatics Special Issue

artículo científico publicado en 2016

Society of Biomolecular Imaging and Informatics Special Issue

artículo científico publicado en 2015

Society of Biomolecular Imaging and Informatics Special Issue

scientific article published on 01 January 2019

Society of Biomolecular Imaging and Informatics Special Issue

scientific article published on 01 August 2018

Society of Biomolecular Imaging and Informatics Special Issue, November 2015

artículo científico publicado en 2015

Society of Biomolecular Imaging and Informatics Special Issue, October 2016

artículo científico publicado en 2016

Society of Biomolecular Imaging and Informatics Special Issue.

artículo científico publicado en 2017

Strategies and challenges for systematically mapping biologically significant molecular pathways regulating carcinoma epithelial-mesenchymal transition.

artículo científico

Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells

artículo científico

Synthetic lethality between CCNE1 amplification and loss of BRCA1.

artículo científico publicado en 2013

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

artículo científico publicado en 2015

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology

artículo científico publicado en 2017

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

scientific article published on 11 November 2020

The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo

artículo científico publicado en 2005

The comparative biology of whey proteins

artículo científico publicado en 2002

Whole-genome multiparametric screening to identify modulators of epithelial-to-mesenchymal transition

artículo científico

Lista de obras de Kaylene J. Simpson

A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens

A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4.

A Phenotypic High-Content Screening Assay to Identify Regulators of Membrane Protein Localization

A functional genetic screen defines the AKT-induced senescence signaling network

A functional genomics screen identifies PCAF and ADA3 as regulators of human granzyme B-mediated apoptosis and Bid cleavage.

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.

A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer

A high-throughput, multiplex cell death assay using an RNAi screening approach

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit.

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species.

Brca1 inactivation induces p27(Kip1)-dependent cell cycle arrest and delayed development in the mouse mammary gland.

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

Colloquium: SBI(2) HCS/HCA Informatics and Data Analysis--Best Practices and Unmet Needs September 15, 2015.

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence.

Comparative high-throughput RNAi screening methodologies in C. elegans and mammalian cells.

Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.

Developmentally-regulated expression of a putative protease inhibitor gene in the lactating mammary gland of the tammar wallaby, Macropus eugenii

Differential expression of the whey acidic protein gene during lactation in the brushtail possum (Trichosurus vulpecula).

Discovering cancer vulnerabilities using high-throughput micro-RNA screening

Dual microRNA Screens Reveal That the Immune-Responsive miR-181 Promotes Henipavirus Entry and Cell-Cell Fusion.

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice

FOXO3a promotes tumor cell invasion through the induction of matrix metalloproteinases.

Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer

Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma

Functional genomics down under: RNAi screening in the Victorian Centre for Functional Genomics

Generation of a functional mammary gland from a single stem cell

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids

High-content assay for measuring intracellular growth of Leishmania in human macrophages

High-throughput approaches to measuring cell death

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

Knocking down the obstacles to functional genomics data sharing

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development.

Maternal regulation of milk composition, milk production, and pouch young development during lactation in the tammar wallaby (Macropus eugenii ).

Metabolic profiling and in vitro assessment of anthelmintic fractions of Picria fel-terrae Lour

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer.

Molecular characterisation and hormone-dependent expression of the porcine whey acidic protein gene

Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens

Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR.

Psidin, a conserved protein that regulates protrusion dynamics and cell migration

Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma

Regulation of cell adhesion and collective cell migration by hindsight and its human homolog RREB1

SBI2 HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium.

Screening of the 'Stasis Box' identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus.

Society of Biomolecular Imaging and Informatics Special Issue

Society of Biomolecular Imaging and Informatics Special Issue

Society of Biomolecular Imaging and Informatics Special Issue

Society of Biomolecular Imaging and Informatics Special Issue

Society of Biomolecular Imaging and Informatics Special Issue, November 2015

Society of Biomolecular Imaging and Informatics Special Issue, October 2016

Society of Biomolecular Imaging and Informatics Special Issue.

Strategies and challenges for systematically mapping biologically significant molecular pathways regulating carcinoma epithelial-mesenchymal transition.

Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells

Synthetic lethality between CCNE1 amplification and loss of BRCA1.

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo

The comparative biology of whey proteins

Whole-genome multiparametric screening to identify modulators of epithelial-to-mesenchymal transition