Lista de obras - Annakaisa Haapasalo - Dominio Público Uruguay

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

artículo científico publicado en 2018

AMP-activated protein kinase: a potential player in Alzheimer's disease

artículo científico publicado en 2011

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. ⬇️

artículo científico publicado en 2003

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

artículo científico publicado en 2011

Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway

scientific article published on 18 June 2019

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus

artículo científico publicado en 2017

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

artículo científico publicado en 2011

Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium

artículo científico

An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population.

artículo científico publicado en 2009

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population.

artículo científico publicado en 2010

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease.

artículo científico publicado en 2012

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.

artículo científico publicado en 2019

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

artículo científico publicado en 2011

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

scientific article published on 06 October 2020

Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats

artículo científico publicado en 2012

C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner

artículo científico publicado en 2019

C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia

artículo científico publicado en 2020

Chronic hyperperfusion and angiogenesis follow subacute hypoperfusion in the thalamus of rats with focal cerebral ischemia.

artículo científico publicado en 2010

Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease

artículo científico publicado en 2020

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

artículo científico publicado en 2012

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

artículo científico publicado en 2011

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death.

artículo científico publicado en 2017

Decreased plasma C-reactive protein levels in 4 allele carriers

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

artículo científico publicado en 2020

Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis

artículo científico publicado en 2009

Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

artículo científico publicado en 2016

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

artículo científico publicado en 2015

Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease

artículo científico publicado en 2013

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease

artículo científico publicado en 2013

Emerging role of Alzheimer's disease-associated ubiquilin-1 in protein aggregation

artículo científico publicado en 2010

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

artículo científico publicado en 2011

Expression of the naturally occurring truncated trkB neurotrophin receptor induces outgrowth of filopodia and processes in neuroblastoma cells

artículo científico publicado en 1999

FRMD4A-cytohesin signaling modulates the cellular release of tau.

artículo científico publicado en 2016

Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium

scientific article published on 17 June 2020

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

artículo científico publicado en 2013

Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease

artículo científico publicado en 2015

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease

artículo científico publicado en 2012

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

artículo científico publicado en 2014

Hypoxia and GABA shunt activation in the pathogenesis of Alzheimer's disease.

artículo científico publicado en 2015

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

artículo científico publicado en 2013

Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape

artículo científico

Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801.

artículo científico publicado en 2001

Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology

artículo científico publicado en 2014

Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples

artículo científico publicado en 2018

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

artículo científico publicado en 2018

Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

artículo científico

Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration.

artículo científico publicado en 2018

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease

scholarly article by Mikael Marttinen et al published 2018 in Frontiers in Neuroscience

Mutation Analysis of the Genes Associated with Parkinson's Disease in a Finnish Cohort of Early-Onset Dementia

scientific article published on 17 June 2020

Mutation Analysis of the Genes Linked to Early Onset Alzheimer's Disease and Frontotemporal Lobar Degeneration

artículo científico publicado en 2019

New risk genes for Alzheimer's disease--biomarkers predicting the disease?

artículo científico publicado en 2013

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

artículo científico publicado en 2009

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

artículo científico publicado en 2017

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

scientific article published on 12 September 2019

Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion

scientific article published on 26 September 2019

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

artículo científico publicado en 2020

Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers

scientific article published on 21 June 2019

Protein aggregation and degradation mechanisms in neurodegenerative diseases

artículo científico publicado en 2013

Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms

artículo científico publicado en 2002

Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

artículo científico publicado en 2015

SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

artículo científico publicado en 2016

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis

scientific article published on 22 May 2020

Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype

artículo científico publicado en 2022

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein

artículo científico publicado en 2018

Synaptic dysfunction and septin protein family members in neurodegenerative diseases

artículo científico publicado en 2015

Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

artículo científico

Targeting ubiquilin-1 in Alzheimer's disease

artículo científico

The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions

scientific article published on 11 September 2020

The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

artículo científico publicado en 2015

The many substrates of presenilin/γ-secretase

artículo científico publicado en 2011

Threshold of heteroplasmic truncating MT-ATP6 mutation in reprogramming, Notch hyperactivation and motor neuron metabolism

artículo científico publicado en 2022

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models

artículo científico publicado en 2014

Transgenic Mice Overexpressing Truncated trkB Neurotrophin Receptors in Neurons Show Increased Susceptibility to Cortical Injury after Focal Cerebral Ischemia

artículo científico publicado en 2000

Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival.

artículo científico publicado en 2001

Ubiquilin-1 modulates γ-secretase-mediated ε-site cleavage in neuronal cells

artículo científico publicado en 2013

Γ-secretase components as predictors of breast cancer outcome

artículo científico publicado en 2013

Lista de obras de Annakaisa Haapasalo

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

AMP-activated protein kinase: a potential player in Alzheimer's disease

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. ⬇️

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium

An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population.

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population.

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease.

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats

C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner

C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia

Chronic hyperperfusion and angiogenesis follow subacute hypoperfusion in the thalamus of rats with focal cerebral ischemia.

Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death.

Decreased plasma C-reactive protein levels in 4 allele carriers

Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques

Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis

Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease

Emerging role of Alzheimer's disease-associated ubiquilin-1 in protein aggregation

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Expression of the naturally occurring truncated trkB neurotrophin receptor induces outgrowth of filopodia and processes in neuroblastoma cells

FRMD4A-cytohesin signaling modulates the cellular release of tau.

Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

Hypoxia and GABA shunt activation in the pathogenesis of Alzheimer's disease.

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape

Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801.

Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology

Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration.

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease

Mutation Analysis of the Genes Associated with Parkinson's Disease in a Finnish Cohort of Early-Onset Dementia

Mutation Analysis of the Genes Linked to Early Onset Alzheimer's Disease and Frontotemporal Lobar Degeneration

New risk genes for Alzheimer's disease--biomarkers predicting the disease?

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers

Protein aggregation and degradation mechanisms in neurodegenerative diseases

Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms

Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis

Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein

Synaptic dysfunction and septin protein family members in neurodegenerative diseases

Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

Targeting ubiquilin-1 in Alzheimer's disease

The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions

The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

The many substrates of presenilin/γ-secretase

Threshold of heteroplasmic truncating MT-ATP6 mutation in reprogramming, Notch hyperactivation and motor neuron metabolism

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models

Transgenic Mice Overexpressing Truncated trkB Neurotrophin Receptors in Neurons Show Increased Susceptibility to Cortical Injury after Focal Cerebral Ischemia

Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival.

Ubiquilin-1 modulates γ-secretase-mediated ε-site cleavage in neuronal cells

Γ-secretase components as predictors of breast cancer outcome