Lista de obras - John F. Wambaugh - Dominio Público Uruguay

A Liver-Centric Multiscale Modeling Framework for Xenobiotics

artículo científico publicado en 2016

A Method for Identifying Prevalent Chemical Combinations in the U.S. Population

artículo científico

Advancements in Life Cycle Human Exposure and Toxicity Characterization

article

Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments

scientific article published on 16 August 2018

An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library

artículo científico

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

artículo científico publicado en 2016

Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization

artículo científico publicado en 2019

Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop

scientific article published on 15 January 2019

Characterization and prediction of chemical functions and weight fractions in consumer products

artículo científico publicado en 2016

Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis

artículo científico publicado en 2021

Comment on: Dong et al. (2017) “Issues raised by the reference doses for perfluorooctonate sulfonate and perfluorooctanoic acid.”

artículo científico publicado en 2018

Comparative pharmacokinetics of perfluorononanoic acid in rat and mouse

artículo científico publicado en 2011

Comparing models for perfluorooctanoic acid pharmacokinetics using Bayesian analysis

artículo científico publicado en 2008

Comparison of modeling approaches to prioritize chemicals based on estimates of exposure and exposure potential

scientific article published on 22 May 2013

Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment

artículo científico publicado en 2016

Computational Tools for ADMET Profiling

Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways

artículo científico publicado en 2018

Correction to Designing QSARs for Parameters of High Throughput Toxicokinetic Models Using Open-Source Descriptors

artículo científico publicado en 2021

Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals

artículo científico publicado en 2020

Defining toxicological tipping points in neuronal network development

artículo científico publicado en 2018

Designing QSARs for Parameters of High-Throughput Toxicokinetic Models Using Open-Source Descriptors

artículo científico publicado en 2021

Development of a consumer product ingredient database for chemical exposure screening and prioritization

artículo científico publicado en 2013

Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis

artículo científico publicado en 2016

Dosimetric Anchoring of Toxicological Studies

Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate

artículo científico publicado en 2013

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

artículo científico publicado en 2016

Empirical Models for Anatomical and Physiological Changes in a Human Mother and Fetus During Pregnancy and Gestation

Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

artículo científico publicado en 2019

Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

artículo científico publicado en 2018

Evaluation and calibration of high-throughput predictions of chemical distribution to tissues

artículo científico publicado en 2017

Exploring consumer exposure pathways and patterns of use for chemicals in the environment

artículo científico publicado en 2015

Force networks and elasticity in granular silos

artículo científico publicado en 2010

From the exposome to mechanistic understanding of chemical-induced adverse effects

artículo científico publicado en 2016

GRADE Guidelines 30: The GRADE Approach to Assessing the Certainty of Modelled Evidence - an Overview in the Context of Health Decision-making

artículo científico publicado en 2020

High throughput heuristics for prioritizing human exposure to environmental chemicals

artículo científico publicado en 2014

High-throughput dietary exposure predictions for chemical migrants from food contact substances for use in chemical prioritization

artículo científico

High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling

artículo científico publicado en 2017

High-throughput models for exposure-based chemical prioritization in the ExpoCast project

artículo científico publicado en 2013

High-throughput screening of chemicals as functional substitutes using structure-based classification models

artículo científico publicado en 2017

High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity

scientific article published on 09 February 2020

Identifiability of PBPK models with applications to dimethylarsinic acid exposure

artículo científico publicado en 2015

Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability

artículo científico publicado en 2017

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme

artículo científico

In vitro to in vivo extrapolation for high throughput prioritization and decision making.

artículo científico publicado en 2017

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

artículo científico publicado en 2015

Incorporating exposure information into the toxicological prioritization index decision support framework

artículo científico publicado en 2012

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

artículo científico publicado en 2010

Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing

artículo científico publicado en 2014

Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA.

artículo científico publicado en 2017

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment

artículo científico publicado en 2011

Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

artículo científico publicado en 2016

Modeling In Vitro Cell-Based Assays Experiments

Modeling single and repeated dose pharmacokinetics of PFOA in mice

artículo científico publicado en 2008

New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

artículo científico publicado en 2020

P68—Parsimonious development of a physiologically based pharmacokinetic model for PFOA

article

Physiologically based pharmacokinetic model use in risk assessment--Why being published is not enough.

artículo científico publicado en 2011

Rapid experimental measurements of physicochemical properties to inform models and testing

artículo científico publicado en 2018

Ratchet-induced segregation and transport of nonspherical grains

artículo científico publicado en 2002

Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays

artículo científico publicado en 2013

Response to perturbations for granular flow in a hopper

artículo científico publicado en 2007

Simple models for granular force networks

article

Simulating microdosimetry in a virtual hepatic lobule

artículo científico publicado en 2010

Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles

artículo científico publicado en 2011

Suspect Screening Analysis of Chemicals in Consumer Products

artículo científico publicado en 2018

Systems toxicology from genes to organs

artículo científico

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

artículo científico publicado en 2017

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

artículo científico publicado en 2019

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

artículo científico publicado en 2016

Toxicity testing in the 21st century: progress in the past decade and future perspectives

scientific article published on 17 December 2019

Toxicokinetic Triage for Environmental Chemicals

artículo científico publicado en 2015

Using nuclear receptor activity to stratify hepatocarcinogens

artículo científico publicado en 2011

Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions

artículo científico publicado en 2019

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

artículo científico publicado en 2018

Virtual tissues in toxicology

artículo científico publicado en 2010

httk: R Package for High-Throughput Toxicokinetics

article

Lista de obras de John F. Wambaugh

A Liver-Centric Multiscale Modeling Framework for Xenobiotics

A Method for Identifying Prevalent Chemical Combinations in the U.S. Population

Advancements in Life Cycle Human Exposure and Toxicity Characterization

Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments

An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization

Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop

Characterization and prediction of chemical functions and weight fractions in consumer products

Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis

Comment on: Dong et al. (2017) “Issues raised by the reference doses for perfluorooctonate sulfonate and perfluorooctanoic acid.”

Comparative pharmacokinetics of perfluorononanoic acid in rat and mouse

Comparing models for perfluorooctanoic acid pharmacokinetics using Bayesian analysis

Comparison of modeling approaches to prioritize chemicals based on estimates of exposure and exposure potential

Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment

Computational Tools for ADMET Profiling

Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways

Correction to Designing QSARs for Parameters of High Throughput Toxicokinetic Models Using Open-Source Descriptors

Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals

Defining toxicological tipping points in neuronal network development

Designing QSARs for Parameters of High-Throughput Toxicokinetic Models Using Open-Source Descriptors

Development of a consumer product ingredient database for chemical exposure screening and prioritization

Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis

Dosimetric Anchoring of Toxicological Studies

Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Empirical Models for Anatomical and Physiological Changes in a Human Mother and Fetus During Pregnancy and Gestation

Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

Evaluation and calibration of high-throughput predictions of chemical distribution to tissues

Exploring consumer exposure pathways and patterns of use for chemicals in the environment

Force networks and elasticity in granular silos

From the exposome to mechanistic understanding of chemical-induced adverse effects

GRADE Guidelines 30: The GRADE Approach to Assessing the Certainty of Modelled Evidence - an Overview in the Context of Health Decision-making

High throughput heuristics for prioritizing human exposure to environmental chemicals

High-throughput dietary exposure predictions for chemical migrants from food contact substances for use in chemical prioritization

High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling

High-throughput models for exposure-based chemical prioritization in the ExpoCast project

High-throughput screening of chemicals as functional substitutes using structure-based classification models

High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity

Identifiability of PBPK models with applications to dimethylarsinic acid exposure

Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme

In vitro to in vivo extrapolation for high throughput prioritization and decision making.

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

Incorporating exposure information into the toxicological prioritization index decision support framework

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing

Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA.

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment

Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

Modeling In Vitro Cell-Based Assays Experiments

Modeling single and repeated dose pharmacokinetics of PFOA in mice

New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

P68—Parsimonious development of a physiologically based pharmacokinetic model for PFOA

Physiologically based pharmacokinetic model use in risk assessment--Why being published is not enough.

Rapid experimental measurements of physicochemical properties to inform models and testing

Ratchet-induced segregation and transport of nonspherical grains

Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays

Response to perturbations for granular flow in a hopper

Simple models for granular force networks

Simulating microdosimetry in a virtual hepatic lobule

Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles

Suspect Screening Analysis of Chemicals in Consumer Products

Systems toxicology from genes to organs

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

Toxicity testing in the 21st century: progress in the past decade and future perspectives

Toxicokinetic Triage for Environmental Chemicals

Using nuclear receptor activity to stratify hepatocarcinogens

Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Virtual tissues in toxicology

httk: R Package for High-Throughput Toxicokinetics