Lista de obras - Laura Gatti - Dominio Público Uruguay

A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system

artículo científico publicado en 1999

A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

artículo científico publicado en 2008

A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line

artículo científico publicado en 2001

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

artículo científico publicado en 2019

Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma.

artículo científico publicado en 2013

Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.

artículo científico publicado en 2002

Apoptosis induced by extracellular glutathione is mediated by H(2)O(2) production and DNA damage

artículo científico publicado en 2000

Axl molecular targeting counteracts aggressiveness but not platinum-resistance of ovarian carcinoma cells

artículo científico publicado en 2017

Camptothecin Resistance in Cancer: Insights into the Molecular Mechanisms of a DNA-Damaging Drug ⬇️

artículo científico publicado el 1 de enero de 2013

Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models

artículo científico publicado en 2003

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells

artículo científico publicado en 2004

Cellular sensitivity to beta-diketonato complexes of ruthenium(III), chromium(III) and rhodium(III).

artículo científico publicado en 2006

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

artículo científico publicado en 2013

Defining targets of modulation of human tumor cell response to cisplatin.

artículo científico publicado en 2008

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

artículo científico publicado en 2003

Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells

artículo científico publicado en 2014

Drug Combinations with HDAC Inhibitors in Antitumor Therapy.

artículo científico publicado en 2015

Drug Combinations with Proteasome Inhibitors in Antitumor Therapy ⬇️

artículo científico publicado el 1 de enero de 2013

Eradication of Ovarian Tumor Xenografts by Locoregional Administration of Targeted Immunotherapy

artículo científico publicado en 2008

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer

artículo científico publicado en 2002

FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.

artículo científico publicado en 2017

Gene expression profiles in the cellular response to a multinuclear platinum complex

artículo científico publicado en 2004

Global gene expression of fission yeast in response to cisplatin.

artículo científico publicado en 2004

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

artículo científico publicado en 2009

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals

artículo científico publicado en 2014

Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.

artículo científico publicado en 2013

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

artículo científico

Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair.

artículo científico publicado en 2003

Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

artículo científico publicado en 2015

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

scientific article published on 16 March 2019

Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells.

artículo científico publicado en 2006

Modulation of sensitivity to antitumor agents by targeting the MAPK survival pathway.

artículo científico publicado en 2013

New mechanisms for old drugs: Insights into DNA-unrelated effects of platinum compounds and drug resistance determinants

artículo científico

Novel Insights into Targeting ATP-Binding Cassette Transporters for Antitumor Therapy ⬇️

artículo científico publicado el 1 de enero de 2011

Novel bis-platinum complexes endowed with an improved pharmacological profile

artículo científico publicado en 2010

Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.

artículo científico publicado en 2014

Orchestration of DSB repair: a novel BRCA2 connection

artículo científico publicado en 2015

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

artículo científico publicado en 2017

PGE2 Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma

scientific article published on 02 March 2020

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

artículo científico publicado en 2016

PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues

artículo científico publicado en 2015

Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.

artículo científico publicado en 2001

Role of the Receptor Tyrosine Kinase Axl and its Targeting in Cancer Cells

artículo científico publicado en 2016

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

artículo científico publicado en 2011

Sensitization of tumor cells by targeting histone deacetylases

artículo científico publicado en 2011

Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells

artículo científico publicado en 2006

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

artículo científico publicado en 2010

Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells

artículo científico publicado en 2012

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

artículo científico publicado en 2016

Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells ⬇️

artículo científico publicado el 1 de enero de 2013

Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor.

artículo científico publicado en 2015

The "stem" of chemoresistance

artículo científico publicado en 2010

The ABC of glycosylation

artículo científico publicado en 2010

The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells

scientific article published on 01 October 1999

The human homolog of fission yeast Rad17 is implicated in tumor growth

artículo científico publicado en 2008

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

scientific article published on January 2010

Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

artículo científico publicado en 2011

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy ⬇️

artículo científico publicado en 2020

Vascular Remodeling in Moyamoya Angiopathy: From Peripheral Blood Mononuclear Cells to Endothelial Cells

artículo científico publicado en 2020

Yeast mutants as a model system for identification of determinants of chemosensitivity.

artículo científico publicado en 2000

p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma

article

Lista de obras de Laura Gatti

A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system

A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma.

Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.

Apoptosis induced by extracellular glutathione is mediated by H(2)O(2) production and DNA damage

Axl molecular targeting counteracts aggressiveness but not platinum-resistance of ovarian carcinoma cells

Camptothecin Resistance in Cancer: Insights into the Molecular Mechanisms of a DNA-Damaging Drug ⬇️

Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells

Cellular sensitivity to beta-diketonato complexes of ruthenium(III), chromium(III) and rhodium(III).

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

Defining targets of modulation of human tumor cell response to cisplatin.

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells

Drug Combinations with HDAC Inhibitors in Antitumor Therapy.

Drug Combinations with Proteasome Inhibitors in Antitumor Therapy ⬇️

Eradication of Ovarian Tumor Xenografts by Locoregional Administration of Targeted Immunotherapy

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer

FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.

Gene expression profiles in the cellular response to a multinuclear platinum complex

Global gene expression of fission yeast in response to cisplatin.

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals

Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair.

Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells.

Modulation of sensitivity to antitumor agents by targeting the MAPK survival pathway.

New mechanisms for old drugs: Insights into DNA-unrelated effects of platinum compounds and drug resistance determinants

Novel Insights into Targeting ATP-Binding Cassette Transporters for Antitumor Therapy ⬇️

Novel bis-platinum complexes endowed with an improved pharmacological profile

Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.

Orchestration of DSB repair: a novel BRCA2 connection

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

PGE2 Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues

Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.

Role of the Receptor Tyrosine Kinase Axl and its Targeting in Cancer Cells

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

Sensitization of tumor cells by targeting histone deacetylases

Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells ⬇️

Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor.

The "stem" of chemoresistance

The ABC of glycosylation

The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells

The human homolog of fission yeast Rad17 is implicated in tumor growth

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy ⬇️

Vascular Remodeling in Moyamoya Angiopathy: From Peripheral Blood Mononuclear Cells to Endothelial Cells

Yeast mutants as a model system for identification of determinants of chemosensitivity.

p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma