Lista de obras - Alma Martelli - Dominio Público Uruguay

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

artículo científico publicado en 2006

1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.

artículo científico publicado en 2008

1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII.

artículo científico publicado en 2005

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

artículo científico publicado en 2013

1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.

artículo científico publicado en 2004

A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis

scientific article published on 27 May 2016

Anomalous Kv 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2 S and persulfidation in skeletal muscle

artículo científico publicado en 2019

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

artículo científico publicado en 2010

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

artículo científico publicado en 2009

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

artículo científico publicado en 2019

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

artículo científico publicado en 2013

Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII.

artículo científico publicado en 2005

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

artículo científico publicado en 2013

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

artículo científico publicado en 2015

Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?

scientific article published on 27 September 2019

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

artículo científico publicado en 2015

Differential effects of fondaparinux and bemiparin on angiogenic and vasculogenesis-like processes

artículo científico publicado en 2012

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H S release in vivo

artículo científico publicado en 2018

Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels

artículo científico publicado en 2017

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

artículo científico publicado en 2009

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin

artículo científico publicado en 2019

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

artículo científico publicado en 2020

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

scientific article published on 15 April 2019

Evaluation of the NO-releasing properties of NO-donor linkers

artículo científico publicado en 2008

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.

artículo científico publicado en 2015

First Examples of H2S-Releasing Glycoconjugates: Stereoselective Synthesis and Anticancer Activities

artículo científico publicado en 2019

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

artículo científico publicado en 2007

Heterocyclic analogs of benzanilide derivatives as potassium channel activators. IX.

artículo científico publicado en 2006

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

artículo científico publicado el 1 de enero de 2012

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

artículo científico publicado en 2015

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

artículo científico publicado en 2014

Hydrogen sulphide: novel opportunity for drug discovery

artículo científico

Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects.

artículo científico publicado en 2017

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

artículo científico publicado en 2012

Inhibitors of the renal outer medullary potassium channel: a patent review

artículo científico

Large conductance Ca(2+)-activated K(+) channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects.

artículo científico publicado en 2013

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

artículo científico publicado en 2014

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol.

artículo científico publicado en 2017

N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors

artículo científico publicado en 2007

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

artículo científico publicado en 2009

NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs

artículo científico publicado en 2004

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

artículo científico publicado en 2013

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

artículo científico publicado en 2006

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

artículo científico publicado en 2006

New amido derivatives as potential BKCa potassium channel activators. XI

artículo científico publicado en 2007

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

artículo científico publicado en 2008

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

artículo científico publicado en 2011

Pathophysiological role of mitochondrial potassium channels and their modulation by drugs.

artículo científico publicado en 2017

Pharmacodynamic hybrids coupling established cardiovascular mechanisms of action with additional nitric oxide releasing properties

artículo científico publicado en 2009

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

artículo científico publicado en 2013

Phosphorylation of AKT and ERK1/2 and mutations of PIK3CA and PTEN are predictive of breast cancer cell sensitivity to everolimus in vitro

artículo científico publicado en 2018

Potassium Channels: A Big Family, Many Different Targets, Great Pharmacological Opportunities

artículo científico publicado en 2018

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle

artículo científico publicado en 2013

QSAR studies on BK channel activators

artículo científico publicado en 2008

Recent efforts in drug discovery on vascular inflammation and consequent atherosclerosis

scientific article published on 30 November 2020

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

artículo científico publicado en 2008

Structural modifications of benzanilide derivatives, effective potassium channel openers. X

Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V.

artículo científico publicado en 2004

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

artículo científico publicado en 2011

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

artículo científico publicado en 2014

Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties

artículo científico publicado en 2010

The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels.

artículo científico publicado en 2017

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage.

artículo científico publicado en 2017

The Renal Outer Medullary Potassium channel (ROMK): an intriguing pharmacological target for an innovative class of diuretic drugs

artículo científico publicado en 2017

The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.

artículo científico publicado en 2013

The novel H2 S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.

artículo científico publicado en 2016

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress

artículo científico publicado en 2016

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

artículo científico publicado en 2013

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury

artículo científico publicado en 2018

Tumor Suppressor Role of hsa-miR-193a-3p and -5p in Cutaneous Melanoma

scientific article published on 27 August 2020

Using hydrogen sulfide to design and develop drugs

artículo científico publicado en 2015

Vascular Effects of H2S-Donors: Fluorimetric Detection of H2S Generation and Ion Channel Activation in Human Aortic Smooth Muscle Cells

artículo científico publicado en 2019

Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels.

artículo científico publicado en 2013

Voltage-operated potassium (Kv) channels contribute to endothelium-dependent vasorelaxation of carvacrol on rat aorta

artículo científico publicado en 2016

Lista de obras de Alma Martelli

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.

1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII.

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.

A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis

Anomalous Kv 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2 S and persulfidation in skeletal muscle

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII.

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Differential effects of fondaparinux and bemiparin on angiogenic and vasculogenesis-like processes

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H S release in vivo

Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

Evaluation of the NO-releasing properties of NO-donor linkers

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.

First Examples of H2S-Releasing Glycoconjugates: Stereoselective Synthesis and Anticancer Activities

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

Heterocyclic analogs of benzanilide derivatives as potassium channel activators. IX.

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

Hydrogen sulphide: novel opportunity for drug discovery

Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects.

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

Inhibitors of the renal outer medullary potassium channel: a patent review

Large conductance Ca(2+)-activated K(+) channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects.

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol.

N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

New amido derivatives as potential BKCa potassium channel activators. XI

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

Pathophysiological role of mitochondrial potassium channels and their modulation by drugs.

Pharmacodynamic hybrids coupling established cardiovascular mechanisms of action with additional nitric oxide releasing properties

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

Phosphorylation of AKT and ERK1/2 and mutations of PIK3CA and PTEN are predictive of breast cancer cell sensitivity to everolimus in vitro

Potassium Channels: A Big Family, Many Different Targets, Great Pharmacological Opportunities

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle

QSAR studies on BK channel activators

Recent efforts in drug discovery on vascular inflammation and consequent atherosclerosis

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

Structural modifications of benzanilide derivatives, effective potassium channel openers. X

Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V.

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties

The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels.

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage.

The Renal Outer Medullary Potassium channel (ROMK): an intriguing pharmacological target for an innovative class of diuretic drugs

The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.

The novel H2 S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury

Tumor Suppressor Role of hsa-miR-193a-3p and -5p in Cutaneous Melanoma

Using hydrogen sulfide to design and develop drugs

Vascular Effects of H2S-Donors: Fluorimetric Detection of H2S Generation and Ion Channel Activation in Human Aortic Smooth Muscle Cells

Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels.

Voltage-operated potassium (Kv) channels contribute to endothelium-dependent vasorelaxation of carvacrol on rat aorta