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Lista de obras de Robert F. Storey

2015 ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-segment Elevation

article

2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevati

artículo científico publicado en 2015

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

artículo científico publicado en 2017

2018 Joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous cardiovascular interventions: a joint consensus document of the

article

2023 ESC Guidelines for the management of acute coronary syndromes

artículo científico publicado en 2023

A randomised controlled trial to assess the antithrombotic effects of aspirin in type 1 diabetes: role of dosing and glycaemic control

artículo científico publicado en 2021

ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial

scientific article published on 29 November 2019

Actualización ESC 2017 sobre el tratamiento antiagregante plaquetario doble en la enfermedad coronaria, desarrollada en colaboración con la EACTS

Admission Levels of DKK1 (Dickkopf-1) Are Associated With Future Cardiovascular Death in Patients With Acute Coronary Syndromes

artículo científico publicado en 2019

Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes)

article

Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis

artículo científico publicado en 2017

Antiplatelet agents for the treatment and prevention of atherothrombosis

artículo científico

Antiplatelet therapy and vascular disease: an update.

artículo científico publicado en 2010

Antiplatelet therapy. Cangrelor succeeds, at last, in PCI.

artículo científico publicado en 2013

Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

scientific article published on 17 March 2019

Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis.

artículo científico publicado en 2018

Antithrombotic therapy in the elderly: expert position paper of the European Society of Cardiology Working Group on Thrombosis.

artículo científico

Aspirin resistance and diabetes mellitus

artículo científico publicado en 2008

Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention

artículo científico publicado en 2018

Association of MicroRNAs and YRNAs With Platelet Function

artículo científico publicado en 2015

Association of Multiple Biomarkers With Risk of All-Cause and Cause-Specific Mortality After Acute Coronary Syndromes: A Secondary Analysis of the PLATO Biomarker Study

scientific article published on 01 December 2018

Association of aspirin dose and vorapaxar safety and efficacy in patients with non-ST-segment elevation acute coronary syndrome (from the TRACER Trial).

artículo científico publicado en 2013

Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial

artículo científico

Association of spontaneous and procedure-related bleeds with short- and long-term mortality after acute coronary syndromes: an analysis from the PLATO trial

artículo científico publicado en 2014

Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes

artículo científico publicado en 2017

Baseline Q waves and time from symptom onset to ST-segment elevation myocardial infarction: insights from PLATO on the influence of sex.

artículo científico publicado en 2015

Baseline Q waves as a prognostic modulator in patients with ST-segment elevation: insights from the PLATO trial

artículo científico publicado en 2012

Benefit and Risks of Aspirin in Addition to Ticagrelor in Acute Coronary Syndromes: A Post Hoc Analysis of the Randomized GLOBAL LEADERS Trial

artículo científico publicado en 2019

Beware the normal angiogram

artículo científico publicado en 2014

Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome

artículo científico publicado en 2016

Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: Insights from the Platelet Inhibition and Patient Outcomes trial

artículo científico publicado en 2015

Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibi

artículo científico

Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial

artículo científico publicado en 2011

Bleeding risk with AZD6140, a reversible P2Y12 receptor antagonist, vs. clopidogrel in patients undergoing coronary artery bypass grafting in the DISPERSE2 trial

artículo científico publicado en 2009

BβArg448Lys polymorphism is associated with altered fibrin clot structure and fibrinolysis in type 2 diabetes ⬇️

artículo científico publicado en 2016

C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes

scientific article published on 26 September 2019

Can we improve the efficacy of low-dose aspirin?

article

Cangrelor for the management and prevention of arterial thrombosis.

artículo científico publicado en 2016

Cangrelor inhibits the binding of the active metabolites of clopidogrel and prasugrel to P2Y12receptorsin vitro

article

Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial

artículo científico publicado en 2014

Causes of mortality with ticagrelor compared with clopidogrel in acute coronary syndromes

artículo científico publicado en 2014

Changes in inflammatory biomarkers in patients treated with ticagrelor or clopidogrel

artículo científico publicado en 2010

Characteristics of dyspnoea and associated clinical outcomes in the CHAMPION PHOENIX study.

artículo científico publicado en 2017

Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes

article

Choices for Potent Platelet Inhibition in Patients With Diabetes Mellitus.

artículo científico publicado en 2016

Choosing a perspective on mortality with DAPT.

artículo científico publicado en 2015

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition

scientific article published on 21 April 2020

Clinical Application of a Novel Genetic Risk Score for Ischemic Stroke in Patients with Cardiometabolic Disease

artículo científico publicado en 2020

Clinical Perspectives and Pearls from the 2015 ESC NSTE-ACS Guidelines.

artículo científico publicado en 2016

Clinical significance of residual platelet reactivity in patients treated with platelet P2Y12 inhibitors

artículo científico publicado en 2016

Clopidogrel in acute coronary syndrome: to genotype or not?

artículo científico publicado en 2008

Clopidogrel resistance

artículo científico publicado en 2004

Common sequence variations in the P2Y12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy.

artículo científico publicado en 2006

Comparison of P2Y12 inhibitors for mortality and stent thrombosis in patients with acute coronary syndromes: Single center study of 10 793 consecutive 'real-world' patients.

artículo científico publicado en 2017

Comparison of Platelet Reactivity in Black Versus White Patients With Acute Coronary Syndromes After Treatment With Ticagrelor.

artículo científico publicado en 2017

Comparison of the pharmacodynamic effects of the platelet ADP receptor antagonists clopidogrel and AR-C69931MX in patients with ischaemic heart disease

artículo científico publicado en 2002

Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study

artículo científico publicado en 2010

Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) tria

artículo científico publicado en 2009

Comparison of two strategies for the management of antiplatelet therapy during urgent surgery

artículo científico publicado en 2005

Consistent platelet inhibition with ticagrelor 60 mg twice-daily following myocardial infarction regardless of diabetes status.

artículo científico publicado en 2017

Contemporary inter-hospital transfer patterns for the management of acute coronary syndrome patients: findings from the EPICOR study

artículo científico publicado en 2014

Cost-Effectiveness of Long-Term Ticagrelor in Patients With Prior Myocardial Infarction: Results From the PEGASUS-TIMI 54 Trial

artículo científico publicado en 2017

Current strategies in antiplatelet therapy--does identification of risk and adjustment of therapy contribute to more effective, personalized medicine in cardiovascular disease?

artículo científico publicado en 2010

Cystatin C and estimated glomerular filtration rate as predictors for adverse outcome in patients with ST-elevation and non-ST-elevation acute coronary syndromes: results from the Platelet Inhibition and Patient Outcomes study

artículo científico publicado en 2011

Cystatin C- and creatinine-based estimates of renal function and their value for risk prediction in patients with acute coronary syndrome: results from the PLATelet Inhibition and Patient Outcomes (PLATO) study

artículo científico publicado en 2013

Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial

artículo científico publicado en 2014

Design and rationale of TROCADERO: A TRial Of Caffeine to Alleviate DyspnEa Related to ticagrelOr.

artículo científico publicado en 2015

Development and clinical use of prasugrel and ticagrelor

artículo científico

Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease

artículo científico publicado en 2020

Dyspnea related to reversibly-binding P2Y12 inhibitors: A review of the pathophysiology, clinical presentation and diagnostics

artículo científico

Dyspnoea management in acute coronary syndrome patients treated with ticagrelor

artículo científico publicado en 2015

ESC/EAS Guidelines for the management of dyslipidaemias The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

artículo científico publicado en 2011

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS).

artículo científico publicado en 2011

Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses

article

Education in atherothrombosis

article

Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial

artículo científico publicado en 2010

Effect of P2Y12 inhibitors on inflammation and immunity

artículo científico publicado en 2015

Effect of Pre-Hospital Ticagrelor During the First 24 h After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction: The ATLANTIC-H²⁴ Analysis

artículo científico publicado en 2016

Effect of genetic variations on ticagrelor plasma levels and clinical outcomes

artículo científico publicado en 2015

Effects of P2Y(1) and P2Y(12) receptor antagonists on platelet aggregation induced by different agonists in human whole blood

artículo científico publicado en 2001

Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes

article

Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial

artículo científico publicado en 2015

Efficacy and safety with ticagrelor in patients with prior myocardial infarction in the approved European label: insights from PEGASUS-TIMI 54

scientific article published on 01 October 2019

Evolving pattern of platelet P2Y12 inhibition in patients with acute coronary syndromes

artículo científico publicado en 2013

Expert position paper on air pollution and cardiovascular disease.

artículo científico publicado en 2014

Expert position paper on the management of antiplatelet therapy in patients undergoing coronary artery bypass graft surgery

artículo científico publicado en 2014

Expert position paper on the role of platelet function testing in patients undergoing percutaneous coronary intervention.

artículo científico publicado en 2013

Exploring Mechanisms of Graft Occlusion

article

Exposure-Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction.

artículo científico publicado en 2016

Factors Contributing to the Lower Mortality With Ticagrelor Compared With Clopidogrel in Patients Undergoing Coronary Artery Bypass Surgery

article

Fibrin clot properties independently predict adverse clinical outcome following acute coronary syndrome: a PLATO substudy ⬇️

artículo científico publicado en 2018

First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.

artículo científico publicado en 2010

Genetics of response to antiplatelet therapy

artículo científico

Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome

artículo científico publicado en 2016

Glycoprotein IIb/IIIa and P2Y12 receptor antagonists yield additive inhibition of platelet aggregation, granule secretion, soluble CD40L release and procoagulant responses

artículo científico publicado en 2005

Growth Differentiation Factor 15 at 1 Month After an Acute Coronary Syndrome Is Associated With Increased Risk of Major Bleeding

artículo científico publicado en 2017

Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study

artículo científico publicado en 2015

Guía ESC 2015 sobre el tratamiento de los síndromes coronarios agudos en pacientes sin elevación persistente del segmento ST

Guía de la ESC/EAS sobre el manejo de las dislipemias

artículo científico publicado en 2011

Guía de práctica clínica de la ESC para el manejo del síndrome coronario agudo en pacientes sin elevación persistente del segmento ST

Health economic analysis of ticagrelor in patients with acute coronary syndromes intended for non-invasive therapy

artículo científico publicado en 2014

Health-related quality of life of ticagrelor versus clopidogrel in patients with acute coronary syndromes-results from the PLATO trial

artículo científico publicado en 2013

Hirudin anticoagulation allows more rapid determination of P2Y₁₂ inhibition by the VerifyNow P2Y12 assay.

artículo científico publicado en 2013

How to improve the concept of individualised antiplatelet therapy with P2Y12 receptor inhibitors--is an algorithm the answer?

artículo científico publicado en 2014

Impact of White Blood Cell Count on Clinical Outcomes in Patients Treated with Aspirin-Free Ticagrelor Monotherapy after Percutaneous Coronary Intervention: Insights from the GLOBAL LEADERS Trial

scientific article published on 21 September 2020

Impact of aspirin dosing on the effects of P2Y12 inhibition in patients with acute coronary syndromes.

artículo científico

Impact of chronic obstructive pulmonary disease and dyspnoea on clinical outcomes in ticagrelor treated patients undergoing percutaneous coronary intervention in the randomized GLOBAL LEADERS trial

artículo científico publicado en 2019

Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial

artículo científico publicado en 2016

Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease

scientific article published on 27 June 2013

Impact of presentation and transfer delays on complete ST-segment resolution before primary percutaneous coronary intervention: insights from the ATLANTIC trial

artículo científico publicado en 2017

Impact of renal function on clinical outcomes after PCI in ACS and stable CAD patients treated with ticagrelor: a prespecified analysis of the GLOBAL LEADERS randomized clinical trial

artículo científico publicado en 2020

Impaired Fibrinolysis Predicts Adverse Outcome in Acute Coronary Syndrome Patients with Diabetes: A PLATO Sub-Study

artículo científico publicado en 2020

Incidence and predictors of stent thrombosis: a single-centre study of 5,833 consecutive patients undergoing coronary artery stenting.

artículo científico publicado en 2013

Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes

artículo científico publicado en 2007

Inhibitory effects of P2Y12 receptor antagonists on TRAP-induced platelet aggregation, procoagulant activity, microparticle formation and intracellular calcium responses in patients with acute coronary syndromes

artículo científico publicado en 2005

Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy

artículo científico publicado en 2010

Interleukin-18 in patients with acute coronary syndromes

artículo científico publicado en 2019

Intolerance to aspirin in patients undergoing percutaneous coronary intervention in the setting of chronic coronary syndromes: perspectives from the ESC 2019 Chronic Coronary Syndromes guidelines

artículo científico publicado en 2020

Ischaemic Events and Stent Thrombosis following Planned Discontinuation of Study Treatment with Ticagrelor or Clopidogrel in the PLATO Study

artículo científico publicado en 2018

Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54.

artículo científico publicado en 2015

Laboratory investigation of platelet function.

artículo científico publicado en 1999

Long-term Tolerability of Ticagrelor for the Secondary Prevention of Major Adverse Cardiovascular Events: A Secondary Analysis of the PEGASUS-TIMI 54 Trial

artículo científico

Long-term antiplatelet therapy following myocardial infarction: implications of PEGASUS-TIMI 54.

artículo científico publicado en 2016

Long-term ticagrelor for secondary prevention in patients with prior myocardial infarction and no history of coronary stenting: insights from PEGASUS-TIMI 54

scientific article published on 07 December 2019

Long-term use of ticagrelor in patients with prior myocardial infarction

artículo científico publicado en 2015

Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study

artículo científico publicado en 2013

Management of antithrombotic therapy after bleeding in patients with coronary artery disease and/or atrial fibrillation: expert consensus paper of the European Society of Cardiology Working Group on Thrombosis.

artículo científico publicado en 2016

Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary or valve interventions: a joint consensus document of the European Society of Cardiology Working Gro

artículo científico publicado en 2014

Monitoring Antiplatelet Therapy

artículo científico publicado en 2017

More transparency for a therapeutic window in platelet P2Y12inhibition?

scientific article published on 05 May 2015

Morphine delays the onset of action of prasugrel in patients with prior history of ST-elevation myocardial infarction

artículo científico publicado en 2016

Multiple antiplatelet effects of clopidogrel are not modulated by statin type in patients undergoing percutaneous coronary intervention

artículo científico publicado en 2004

NLRC4 Inflammasome Is an Important Regulator of Interleukin-18 Levels in Patients With Acute Coronary Syndromes: Genome-Wide Association Study in the PLATelet inhibition and patient Outcomes Trial (PLATO).

artículo científico publicado en 2015

Near patient anti-platelet response testing over time and gene analysis in patients admitted with acute coronary syndromes.

artículo científico publicado en 2012

New Antithrombotic Drugs in Acute Coronary Syndrome

artículo científico publicado en 2020

New P2Y₁₂ inhibitors.

artículo científico publicado en 2011

No misrepresentation of vital status follow-up in PLATO: predefined analyses guarantee the integrity of the benefits of ticagrelor over clopidogrel in the PLATO trial: Commentary on: DiNicolantonio JJ, Tomek A, Misrepresentation of vital status foll

artículo científico publicado en 2014

Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel

artículo científico publicado en 2014

Non-vitamin K antagonist oral anticoagulants (NOACs): clinical evidence and therapeutic considerations

artículo científico

Optimal Management of Antiplatelet Therapy and Proton Pump Inhibition Following Percutaneous Coronary Intervention

article

Oral anticoagulants in coronary heart disease (Section IV). Position paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

artículo científico publicado en 2016

Osteoprotegerin Is Associated With Major Bleeding But Not With Cardiovascular Outcomes in Patients With Acute Coronary Syndromes: Insights From the PLATO (Platelet Inhibition and Patient Outcomes) Trial

artículo científico publicado en 2018

Outcome and causes of renal deterioration evaluated by serial cystatin C measurements in acute coronary syndrome patients—Results from the PLATelet inhibition and patient Outcomes (PLATO) study

scientific article published on 17 October 2012

Outcomes after planned invasive or conservative treatment strategy in patients with non-ST-elevation acute coronary syndrome and a normal value of high sensitivity troponin at randomisation: A Platelet Inhibition and Patient Outcomes (PLATO) trial b

artículo científico publicado en 2016

P2Y12 receptor inhibition and effect of morphine in patients undergoing primary PCI for ST-segment elevation myocardial infarction

scientific article published on 19 May 2015

PAR-1 genotype influences platelet aggregation and procoagulant responses in patients with coronary artery disease prior to and during clopidogrel therapy

artículo científico publicado en 2005

PAR1 antagonists inhibit thrombin-induced platelet activation whilst leaving the PAR4-mediated response intact

artículo científico publicado en 2014

Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial

scientific article published on 24 April 2019

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes

scientific article published on 14 November 2019

Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors.

artículo científico publicado en 2011

Platelet Inhibition With Ticagrelor 60 mg Versus 90 mg Twice Daily in the PEGASUS-TIMI 54 Trial

artículo científico publicado en 2016

Platelet P2Y 12 Receptor Influences the Vessel Wall Response to Arterial Injury and Thrombosis

artículo científico publicado en 2008

Platelet P2Y12 Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model.

artículo científico publicado en 2015

Platelet function testing and prediction of procedural bleeding risk

artículo científico publicado en 2013

Platelet function testing in acute cardiac care - is there a role for prediction or prevention of stent thrombosis and bleeding?

artículo científico publicado en 2014

Platelet reactivity during ticagrelor maintenance therapy: a patient-level data meta-analysis

artículo científico publicado en 2014

Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome.

artículo científico

Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development.

artículo científico publicado en 2008

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study

article

Population pharmacokinetics of ticagrelor and AR-C124910XX in patients with prior myocardial infarction

Population pharmacokinetics of ticagrelor in patients with acute coronary syndromes

artículo científico publicado en 2016

Post-Discharge Bleeding and Mortality Following Acute Coronary Syndromes With or Without PCI

scientific article published on 01 July 2020

Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel.

artículo científico publicado en 2010

Pre-hospital ticagrelor in ST-segment elevation myocardial infarction in the French ATLANTIC population

artículo científico publicado en 2017

Prevalence and relevance of abnormal glucose metabolism in acute coronary syndromes: insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

artículo científico publicado en 2019

Prevention of Stroke with Ticagrelor in Patients with Prior Myocardial Infarction: Insights from PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin

artículo científico

Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes—Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

article

Prognostic impact of baseline inflammatory markers in patients with acute coronary syndromes treated with ticagrelor and clopidogrel

scientific article published on 23 December 2019

Pulmonary Function in Patients With Acute Coronary Syndrome Treated With Ticagrelor or Clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] Pulmonary Function Substudy)

article

Quantitative ST-depression in acute coronary syndromes: the PLATO electrocardiographic substudy

artículo científico publicado en 2013

Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.

artículo científico publicado en 2009

Reduction in Ischemic Events With Ticagrelor in Diabetic Patients With Prior Myocardial Infarction in PEGASUS-TIMI 54.

artículo científico publicado en 2016

Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO Study.

artículo científico

Regional variation in patients and outcomes in the GLOBAL LEADERS trial

artículo científico publicado en 2020

Relationship Between Early and Late Nonsustained Ventricular Tachycardia and Cardiovascular Death in Patients With Acute Coronary Syndrome in the Platelet Inhibition and Patient Outcomes (PLATO) Trial

artículo científico

Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function

artículo científico publicado en 2010

Relative efficacy and safety of ticagelor vs clopidogrel as a function of time to invasive management in non-ST-segment elevation acute coronary syndrome in the PLATO trial

artículo científico publicado en 2017

Republished Education in Heart: New P2Y12inhibitors

article

Response to letter regarding article, "Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial".

artículo científico publicado en 2014

Response to letter regarding article, "Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials".

artículo científico publicado en 2013

Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study

artículo científico publicado en 2010

Response variability to P2Y12 receptor inhibitors: expectations and reality

artículo científico publicado en 2013

Reversal strategies for non-vitamin K antagonist oral anticoagulants: a critical appraisal of available evidence and recommendations for clinical management-a joint position paper of the European Society of Cardiology Working Group on Cardiovascular

artículo científico publicado en 2015

Review of the accumulated PLATO documentation supports reliable and consistent superiority of ticagrelor over clopidogrel in patients with acute coronary syndrome: Commentary on: DiNicolantonio JJ, Tomek A, Inactivations, deletions, non-adjudication

artículo científico publicado en 2013

ST Elevation Acute Coronary Syndromes in PLATO

article

ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy

artículo científico

Safety and efficacy of ticagrelor and clopidogrel in primary percutaneous coronary intervention

artículo científico publicado en 2016

Safety of ticagrelor in patients with baseline conduction abnormalities: A PLATO (Study of Platelet Inhibition and Patient Outcomes) analysis

artículo científico publicado en 2018

Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE

artículo científico publicado en 2007

Stability of VerifyNow P2Y12 assay results with citrate anticoagulation as compared to hirudin anticoagulation over 20-min period

artículo científico publicado en 2014

Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques

artículo científico publicado en 2010

Stent Thrombosis With Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes

article

Stent Thrombosis in Patients With Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial

scientific article published on 11 November 2019

Studies of the interaction of ticagrelor with the P2Y13 receptor and with P2Y13-dependent pro-platelet formation by human megakaryocytes

artículo científico publicado en 2016

The RAPID-CTCA trial (Rapid Assessment of Potential Ischaemic Heart Disease with CTCA) - a multicentre parallel-group randomised trial to compare early computerised tomography coronary angiography versus standard care in patients presenting with sus

artículo científico publicado en 2016

The active metabolite of prasugrel effectively blocks the platelet P2Y12 receptor and inhibits procoagulant and pro-inflammatory platelet responses

artículo científico publicado en 2008

The association of body mass index with long-term clinical outcomes after ticagrelor monotherapy following abbreviated dual antiplatelet therapy in patients undergoing percutaneous coronary intervention: a prespecified sub-analysis of the GLOBAL LEA

artículo científico publicado en 2020

The central role of the P2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity

scientific article published on 01 September 2000

The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies

artículo científico publicado en 2011

The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial

artículo científico publicado en 2014

The future of P2Y12 receptor antagonists

artículo científico

The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) trial: results of the continuous electroca

artículo científico publicado en 2011

The right oral antithrombotics in acute coronary syndromes

artículo científico publicado en 2009

The role of platelets in inflammation.

artículo científico publicado en 2015

Thrombin-receptor antagonist vorapaxar in acute coronary syndromes

artículo científico publicado en 2011

Ticagrelor

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Ticagrelor Versus Clopidogrel in Elderly Patients With Acute Coronary Syndromes

artículo científico publicado en 2012

Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery

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Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes and Chronic Obstructive Pulmonary Disease: An Analysis From the Platelet Inhibition and Patient Outcomes (PLATO) Trial

artículo científico publicado en 2015

Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial

artículo científico

Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima.

artículo científico publicado en 2010

Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial

artículo científico publicado en 2014

Ticagrelor for Prevention of Ischemic Events After Myocardial Infarction in Patients With Peripheral Artery Disease

artículo científico publicado en 2016

Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials

artículo científico publicado en 2013

Ticagrelor in patients with heart failure after acute coronary syndromes-Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

artículo científico publicado en 2019

Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis

artículo científico publicado en 2015

Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial

artículo científico

Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis

artículo científico publicado en 2010

Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.

artículo científico

Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial

artículo científico publicado en 2011

Ticagrelor vs. clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: results from the PLATO trial

artículo científico publicado en 2014

Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.

artículo científico publicado en 2009

Ticagrelor: agonising over its mechanisms of action.

artículo científico publicado en 2016

Triple therapy for atrial fibrillation and percutaneous coronary intervention: a contemporary review.

artículo científico publicado en 2014

Update on lipids, inflammation and atherothrombosis

article

Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary Intervention

artículo científico publicado en 2019

Utilisation of novel anti-platelet agents: evidence, guidelines and proven patients’ value

article

Utility of a whole blood single platelet counting assay to monitor the effects of tirofiban in patients with acute coronary syndromes scheduled for coronary intervention

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Vessel wall, not platelet, P2Y12 potentiates early atherogenesis

artículo científico publicado en 2014

Vorapaxar in acute coronary syndrome patients undergoing coronary artery bypass graft surgery: subgroup analysis from the TRACER trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome).

artículo científico publicado en 2013

What drives thrombogenesis despite antiplatelet therapy in diabetes mellitus?

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Wytyczne ESC dotyczące postępowania w ostrych zespołach wieńcowych bez przetrwałego uniesienia odcinka ST w 2015 roku

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[2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevat

artículo científico publicado en 2016

[ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment e

scientific article published on 01 March 2012

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