Lista de obras - Paul W Denny - Dominio Público Uruguay

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation

scientific article published on 19 December 2019

A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.

artículo científico publicado en 2018

A plastid of probable green algal origin in Apicomplexan parasites.

artículo científico publicado en 1997

A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase

artículo científico publicado en 2010

Acylation-dependent Protein Export in Leishmania

artículo científico publicado en 2000

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity.

artículo científico publicado en 2016

An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei

artículo científico publicado en 2005

Antimicrobial peptides for leishmaniasis.

artículo científico publicado en 2010

Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing.

artículo científico publicado en 2013

Chalcones identify cTXNPx as a potential antileishmanial drug target

artículo científico publicado en 2021

Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct

artículo científico publicado en 2015

Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant.

artículo científico publicado en 2005

Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes

artículo científico

Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.

artículo científico publicado en 2003

Evaluation of the <i>Leishmania</i> Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach

artículo científico publicado en 2024

Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis

artículo científico

Evidence for a Single Origin of the 35 kb Plastid DNA in Apicomplexans

artículo científico publicado en 1998

Exploring Leishmania major inositol phosphorylceramide synthase (LmjIPCS): insights into the ceramide binding domain

artículo científico publicado en 2011

Expression levels of inositol phosphorylceramide synthase modulate plant responses to biotic and abiotic stress in Arabidopsis thaliana

artículo científico publicado en 2019

Expression of the AM gene locus in infective stages of Leishmania

artículo científico publicado en 2000

Functional Analyses of a Putative, Membrane-Bound, Peroxisomal Protein Import Mechanism from the Apicomplexan Protozoan

article

Functional analyses of differentially expressed isoforms of the Arabidopsis inositol phosphorylceramide synthase

artículo científico publicado en 2010

Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites

artículo científico publicado en 2017

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform.

artículo científico publicado en 2018

Investigating the anti-leishmanial effects of linear peptoids.

artículo científico publicado en 2014

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

artículo científico publicado en 2002

Leishmania major: clathrin and adaptin complexes of an intra-cellular parasite

artículo científico publicado en 2004

Lipid metabolism as a therapeutic target.

artículo científico publicado en 2012

Lytic reactions of drugs with lipid membranes

artículo científico publicado en 2018

Meeting report: Molecular Parasitology XI, Woods Hole, USA, September 17-21, 2000

artículo científico publicado en 2001

Microbial protein targets: towards understanding and intervention

artículo científico publicado en 2017

Mining for natural product antileishmanials in a fungal extract library

scientific article published on 11 June 2019

Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania

artículo científico publicado en 2001

Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa.

artículo científico publicado en 2004

Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art

artículo científico publicado en 2017

Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets ⬇️

artículo científico publicado el 9 de febrero de 2012

Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii

artículo científico publicado en 2012

Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity.

artículo científico publicado en 2004

Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa.

artículo científico publicado en 2011

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

scholarly article published by John G M Mina in 2018

The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions

scientific article published on 02 November 2021

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.

artículo científico publicado en 2009

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis

artículo científico publicado en 2017

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis - Corrigendum.

artículo científico publicado en 2017

The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system.

artículo científico publicado en 2002

The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity.

artículo científico publicado en 2019

The in vivo conformation of the plastid DNA of Toxoplasma gondii: implications for replication

artículo científico publicado en 2001

The protozoan inositol phosphorylceramide synthase: a novel drug target that defines a new class of sphingolipid synthase

artículo científico publicado en 2006

The role of phosphoglycans in the susceptibility of Leishmania mexicana to the temporin family of anti-microbial peptides.

artículo científico publicado en 2015

The utility of yeast as a tool for cell-based, target-directed high-throughput screening.

artículo científico publicado en 2013

Thiostrepton binds to malarial plastid rRNA.

artículo científico publicado en 1997

Yeast as a potential vehicle for neglected tropical disease drug discovery

artículo científico publicado en 2014

Yeast: bridging the gap between phenotypic and biochemical assays for high-throughput screening

scientific article published on 16 October 2018

Lista de obras de Paul W Denny

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation

A complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the Leishmania metabolome caused by miltefosine.

A plastid of probable green algal origin in Apicomplexan parasites.

A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase

Acylation-dependent Protein Export in Leishmania

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity.

An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei

Antimicrobial peptides for leishmaniasis.

Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing.

Chalcones identify cTXNPx as a potential antileishmanial drug target

Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct

Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant.

Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes

Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.

Evaluation of the <i>Leishmania</i> Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach

Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis

Evidence for a Single Origin of the 35 kb Plastid DNA in Apicomplexans

Exploring Leishmania major inositol phosphorylceramide synthase (LmjIPCS): insights into the ceramide binding domain

Expression levels of inositol phosphorylceramide synthase modulate plant responses to biotic and abiotic stress in Arabidopsis thaliana

Expression of the AM gene locus in infective stages of Leishmania

Functional Analyses of a Putative, Membrane-Bound, Peroxisomal Protein Import Mechanism from the Apicomplexan Protozoan

Functional analyses of differentially expressed isoforms of the Arabidopsis inositol phosphorylceramide synthase

Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform.

Investigating the anti-leishmanial effects of linear peptoids.

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.

Leishmania major: clathrin and adaptin complexes of an intra-cellular parasite

Lipid metabolism as a therapeutic target.

Lytic reactions of drugs with lipid membranes

Meeting report: Molecular Parasitology XI, Woods Hole, USA, September 17-21, 2000

Microbial protein targets: towards understanding and intervention

Mining for natural product antileishmanials in a fungal extract library

Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania

Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa.

Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art

Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets ⬇️

Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii

Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity.

Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa.

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis

The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis - Corrigendum.

The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system.

The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity.

The in vivo conformation of the plastid DNA of Toxoplasma gondii: implications for replication

The protozoan inositol phosphorylceramide synthase: a novel drug target that defines a new class of sphingolipid synthase

The role of phosphoglycans in the susceptibility of Leishmania mexicana to the temporin family of anti-microbial peptides.

The utility of yeast as a tool for cell-based, target-directed high-throughput screening.

Thiostrepton binds to malarial plastid rRNA.

Yeast as a potential vehicle for neglected tropical disease drug discovery

Yeast: bridging the gap between phenotypic and biochemical assays for high-throughput screening