Filtros de búsqueda

Lista de obras de David J. Brayden

A comparison of three Peyer's patch "M-like" cell culture models: particle uptake, bacterial interaction, and epithelial histology

artículo científico publicado en 2017

A head-to-head multi-parametric high content analysis of a series of medium chain fatty acid intestinal permeation enhancers in Caco-2 cells

scientific article published on 01 November 2014

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.

artículo científico publicado en 2017

A novel in vitro electrophysiological bioassay for transport of loperamide across intestinal epithelia

scientific article published on 01 July 1997

A novel method for culturing sweat gland epithelia: comparison of normal and cystic fibrosis tissues

artículo científico publicado en 1990

A tertiary amino-containing polymethacrylate polymer protects mucus-covered intestinal epithelial monolayers against pathogenic challenge.

artículo científico publicado en 2007

Advances in PEGylation of important biotech molecules: delivery aspects

artículo científico publicado en 2008

Altered sensitivity to amiloride in cystic fibrosis. Observations using cultured sweat glands

artículo científico publicado en 1990

Amphiphilic star polypept(o)ides as nanomeric vectors in mucosal drug delivery

scientific article published on 28 April 2020

An Assessment of the Permeation Enhancer, 1-phenyl-piperazine (PPZ), on Paracellular Flux Across Rat Intestinal Mucosae in Ussing Chambers.

artículo científico publicado en 2016

An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer

artículo científico publicado en 2020

An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis

artículo científico publicado en 2013

Antibacterial effects of poly(2-(dimethylamino ethyl)methacrylate) against selected gram-positive and gram-negative bacteria

artículo científico publicado en 2010

Application of Permeation Enhancers in Oral Delivery of Macromolecules: An Update

artículo científico publicado en 2019

Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers

artículo científico publicado en 2007

Binding and uptake of biodegradable poly-DL-lactide micro- and nanoparticles in intestinal epithelia.

artículo científico

Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles

artículo científico publicado en 2017

Catching target receptors for drug and vaccine delivery using TOGA gene expression profiling.

artículo científico publicado en 2002

Cell culture modeling of specialized tissue: identification of genes expressed specifically by follicle-associated epithelium of Peyer's patch by expression profiling of Caco-2/Raji co-cultures.

artículo científico publicado en 2004

Chloride-led disruption of the intestinal mucous layer impedes Salmonella invasion: evidence for an 'enteric tear' mechanism

artículo científico publicado en 2011

Coated minispheres of salmon calcitonin target rat intestinal regions to achieve systemic bioavailability: Comparison between intestinal instillation and oral gavage

artículo científico publicado en 2016

Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer

scientific article published on 23 January 2013

Comparison of methodologies for evaluating regional intestinal permeability

scientific article published on 01 January 1997

Conjugation of salmon calcitonin to a combed-shaped end functionalized poly(poly(ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate

artículo científico publicado en 2009

Controlled release drug delivery in farmed animals: commercial challenges and academic opportunities.

artículo científico publicado en 2009

Controlled release technologies for drug delivery

artículo científico publicado en 2003

CriticalSorb™ promotes permeation of flux markers across isolated rat intestinal mucosae and Caco-2 monolayers

scientific article published on 26 May 2012

Cultured human sweat gland epithelia: isolation of glands using neutral red

artículo científico publicado en 1995

Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials.

artículo científico publicado en 2016

Cystic Fibrosis, the CFTR, and Rectifying Cl- Channels ⬇️

artículo científico publicado el 1 de enero de 1991

Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules

artículo científico publicado en 2016

Development of nanotoxicology: implications for drug delivery and medical devices

artículo científico

Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.

artículo científico publicado en 2008

Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts

artículo científico publicado en 2012

Drug delivery systems in domestic animal species.

scientific article published on January 2010

Editorial overview: New technologies: drug delivery and medical devices combinations, more than the sum of the parts

artículo científico publicado en 2017

Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease

artículo científico publicado en 2007

Effects of surfactant-based permeation enhancers on mannitol permeability, histology, and electrogenic ion transport responses in excised rat colonic mucosae

artículo científico publicado en 2018

Efficacious intestinal permeation enhancement induced by the sodium salt of 10-undecylenic acid, a medium chain fatty acid derivative

artículo científico publicado en 2014

Encapsulation in biodegradable microparticles enhances serum antibody response to parenterally-delivered beta-amyloid in mice

scientific article published on 01 July 2001

Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models.

artículo científico publicado en 2017

Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies

scientific article published on 31 October 2019

Evaluation of alkylmaltosides as intestinal permeation enhancers: comparison between rat intestinal mucosal sheets and Caco-2 monolayers

artículo científico publicado en 2012

Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies

artículo científico publicado en 2009

Evaluation of intestinal absorption enhancement and local mucosal toxicity of two promoters. I. Studies in isolated rat and human colonic mucosae

artículo científico publicado en 2009

Evolving peptides for oral intake

artículo científico publicado en 2020

Expression of specific markers and particle transport in a new human intestinal M-cell model

scientific article published on 01 December 2000

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

artículo científico publicado en 2014

Formulation strategies to improve oral peptide delivery

artículo científico publicado en 2014

Growth and characterisation of a cell culture model of the feline blood-brain barrier

scientific article published on 22 September 2005

Heparin absorption across the intestine: effects of sodium N-[8-(2-hydroxybenzoyl)amino]caprylate in rat in situ intestinal instillations and in Caco-2 monolayers

scientific article published on 01 December 1997

Hepatic gateways.

artículo científico publicado en 2016

High content analysis of cytotoxic effects of pDMAEMA on human intestinal epithelial and monocyte cultures

artículo científico publicado en 2010

High content analysis to determine cytotoxicity of the antimicrobial peptide, melittin and selected structural analogs

artículo científico publicado en 2011

High-content analysis for drug delivery and nanoparticle applications

artículo científico

Human eccrine sweat gland epithelial cultures express ductal characteristics

artículo científico publicado en 1988

Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin

artículo científico publicado en 2009

In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes

artículo científico publicado en 2010

In vitro and in vivo preclinical evaluation of a minisphere emulsion-based formulation (SmPill®) of salmon calcitonin

artículo científico publicado en 2015

In vitro interactions between the oral absorption promoter, sodium caprate (C(10)) and S. typhimurium in rat intestinal ileal mucosae

artículo científico publicado en 2007

Increased intestinal permeability in rats subjected to traumatic frontal lobe percussion brain injury

artículo científico publicado en 2008

Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C)

artículo científico publicado en 2019

Intestinal permeation enhancers for oral peptide delivery

artículo científico publicado en 2016

Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation

artículo científico publicado en 2018

Introduction for the special issue on recent advances in drug delivery across tissue barriers

artículo científico publicado en 2016

Investigation of coco-glucoside as a novel intestinal permeation enhancer in rat models

artículo científico publicado en 2014

Investigations of Piperazine Derivatives as Intestinal Permeation Enhancers in Isolated Rat Intestinal Tissue Mucosae

artículo científico publicado en 2020

Ion transport in cultured epithelia from human sweat glands: comparison of normal and cystic fibrosis tissues

artículo científico publicado en 1991

Iontophoresis-enhanced absorptive flux of polar molecules across intestinal tissue in vitro

artículo científico publicado en 2000

Keynote review: intestinal Peyer's patch M cells and oral vaccine targeting.

artículo científico publicado en 2005

Labrasol® and salts of medium chain fatty acids can be combined in low concentrations to increase the permeability of a macromolecule marker across isolated rat intestinal mucosae.

artículo científico publicado en 2018

Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies

scientific article published on 08 August 2019

Lymphocyte migration through the blood-brain barrier (BBB) in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and tumour necrosis factor (TNF)-alpha within the central nervous system (CNS): studies u

artículo científico publicado en 2009

Mechanisms of action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its antidiarrhoeal actions

article

Melittin as a permeability enhancer II: in vitro investigations in human mucus secreting intestinal monolayers and rat colonic mucosae.

artículo científico publicado en 2007

Melittin as an epithelial permeability enhancer I: investigation of its mechanism of action in Caco-2 monolayers

scientific article published on 21 March 2007

Microparticle vaccine approaches to stimulate mucosal immunisation.

artículo científico publicado en 2001

Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro.

artículo científico publicado en 2008

Nanoparticle passage through porcine jejunal mucus: Microfluidics and rheology

artículo científico publicado en 2016

Opportunities for drug-delivery research in nutraceuticals and functional foods?

artículo científico publicado en 2013

Oral absorption enhancement: taking the next steps in therapeutic delivery

artículo científico publicado en 2010

Oral delivery of peptides: opportunities and issues for translation.

artículo científico publicado en 2016

Oral peptide delivery: prioritizing the leading technologies

artículo científico publicado en 2011

PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights

artículo científico publicado en 2010

Peptidoglycan recognition protein expression in mouse Peyer's Patch follicle associated epithelium suggests functional specialization

artículo científico publicado en 2003

Per Artursson's major contributions to the Caco-2 cell literature in Pharmaceutical Sciences

artículo científico publicado en 2020

Pharmacology applied: delivering the goods

artículo científico publicado en 2006

Phosphine-mediated one-pot thiol-ene "click" approach to polymer-protein conjugates

artículo científico publicado en 2009

Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin

scientific article published on 31 July 2018

Poly(Ethylene glycol)-based backbones with high peptide loading capacities.

artículo científico publicado en 2014

Progress in the delivery of nanoparticle constructs: towards clinical translation.

artículo científico publicado en 2014

Progress in the formulation and delivery of somatostatin analogs for acromegaly

artículo científico publicado en 2017

Protection against Bordetella pertussis infection following parenteral or oral immunization with antigens entrapped in biodegradable particles: effect of formulation and route of immunization on induction of Th1 and Th2 cells

artículo científico publicado en 2001

Rat, ovine and bovine Peyer's patches mounted in horizontal diffusion chambers display sampling function

artículo científico publicado en 2006

Redox-mediated angiogenesis in the hypoxic joint of inflammatory arthritis

artículo científico publicado en 2014

Resistance of Staphylococcus aureus to the cationic antimicrobial agent poly(2-(dimethylamino ethyl)methacrylate) (pDMAEMA) is influenced by cell-surface charge and hydrophobicity

scientific article published on 10 March 2011

Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate.

artículo científico publicado en 2010

Safety concerns over the use of intestinal permeation enhancers: A mini-review

artículo científico publicado en 2016

Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein.

artículo científico publicado en 2005

Silica-Coated Nanoparticles with a Core of Zinc, l-Arginine, and a Peptide Designed for Oral Delivery

artículo científico publicado en 2019

Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition

artículo científico publicado en 2018

Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol.

artículo científico publicado en 2015

Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro

artículo científico publicado en 2015

Stilbenes stimulate T84 Cl- secretion by elevating Ca2+.

artículo científico publicado en 1993

Stomaching Drug Delivery

artículo científico publicado en 2019

Synchronous transporting activity in epithelial cells in relation to intracellular calcium concentration

artículo científico publicado en 1991

TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis

artículo científico publicado en 2018

Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles.

artículo científico publicado en 2005

Targeting polymerised liposome vaccine carriers to intestinal M cells

artículo científico publicado en 2001

Thapsigargin, a new calcium-dependent epithelial anion secretagogue

artículo científico publicado en 1989

The 2nd Annual Irish Drug Delivery Network Conference with UK and Ireland Controlled Release Society: advancing drug delivery

artículo científico publicado en 2010

The challenges and future of oral drug delivery: An interview with David Brayden

artículo científico publicado en 2016

The effect of plant sterol-enriched turkey meat on cholesterol bio-accessibility during in vitro digestion and Caco-2 cell uptake.

artículo científico publicado en 2017

The mycotoxin patulin increases colonic epithelial permeability in vitro

artículo científico publicado en 2012

The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition

artículo científico publicado en 2013

Track analysis of the passage of rhodamine-labeled liposomes across porcine jejunal mucus in a microchannel device.

artículo científico publicado en 2018

Transepithelial transport of PAMAM dendrimers across isolated rat jejunal mucosae in ussing chambers.

artículo científico publicado en 2014

Translocation of Vibrio parahaemolyticus across an in vitro M cell model.

artículo científico publicado en 2013

Zinc sulphate attenuates chloride secretion in human colonic mucosae in vitro

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda