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Lista de obras de Yijuang Chern

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

artículo científico publicado en 2013

A new drug design targeting the adenosinergic system for Huntington's disease

artículo científico publicado en 2011

A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor

artículo científico publicado en 2013

AMPK-mediated regulation of neuronal metabolism and function in brain diseases

artículo científico

AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

artículo científico publicado en 2014

Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis

artículo científico publicado en 2015

Aberrant astrocytes impair vascular reactivity in Huntington disease

artículo científico publicado en 2015

Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.

artículo científico publicado en 2014

Adenosine A(2A) receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina

artículo científico publicado en 2014

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

article

Adenosine receptor neurobiology: overview.

artículo científico

Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin

artículo científico publicado en 1988

Adenosine receptors and Huntington's disease.

artículo científico publicado en 2014

An important functional role of the N terminus domain of type VI adenylyl cyclase in Galphai-mediated inhibition

artículo científico publicado en 2004

Aspects of the general biology of adenosine A2A signaling.

artículo científico publicado en 2007

CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

artículo científico publicado en 2005

Characterization of the rat A2A adenosine receptor gene: a 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system

artículo científico publicado en 2003

Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum

artículo científico publicado en 1996

Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect

artículo científico publicado en 2015

Dendritic trafficking of brain‐derived neurotrophic factor mRNA: regulation by translin‐dependent and ‐independent mechanisms

artículo científico publicado el 20 de enero de 2011

Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.

artículo científico publicado en 2014

Distribution and regulation of rab3C, a small molecular weight GTP-binding protein

artículo científico publicado en 1994

Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease

artículo científico publicado en 2011

Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease

scientific journal article

Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown

artículo científico publicado en 2015

Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs

artículo científico publicado en 2015

Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.

artículo científico publicado en 2012

Enhancement of brain-type creatine kinase activity ameliorates neuronal deficits in Huntington's disease

artículo científico publicado en 2013

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

artículo científico publicado en 2021

Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease

artículo científico publicado en 2016

Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade

artículo científico publicado en 2002

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes

artículo científico publicado en 2008

Expression of type VI adenylyl cyclase in the central nervous system: implication for a potential regulator of multiple signals in different neurotransmitter systems

artículo científico publicado en 1998

Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease

artículo científico publicado en 2019

High Protein Diet and Huntington's Disease

artículo científico publicado en 2015

Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models.

artículo científico publicado en 2011

Identification of nuclear factor 1 (NF1) as a transcriptional modulator of rat A(2A) adenosine receptor

artículo científico publicado en 2003

Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies.

artículo científico publicado en 2011

Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)

scientific journal article

Inhibition of catecholamine secretion from bovine chromaffin cells by adenine nucleotides and adenosine

scientific article published on 01 May 1987

Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease

artículo científico publicado en 2014

Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats

artículo científico publicado en 1995

Lack of type VI adenylyl cyclase (AC6) leads to abnormal sympathetic tone in neonatal mice

artículo científico publicado en 2013

Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus

artículo científico publicado en 2009

Modulation of dopamine transporter activity by nicotinic acetylcholine receptors and membrane depolarization in rat pheochromocytoma PC12 cells

artículo científico publicado en 1999

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

artículo científico publicado en 2010

N-glycosylation and residues Asn805 and Asn890 are involved in the functional properties of type VI adenylyl cyclase

artículo científico publicado en 2001

Neuroprotective Principles from Gastrodia elata

artículo científico publicado en 2007

Neurovascular abnormalities in brain disorders: highlights with angiogenesis and magnetic resonance imaging studies

artículo científico publicado en 2013

Neurovascular abnormalities in humans and mice with Huntington's disease

artículo científico publicado en 2013

Novel regulation of adenylyl cyclases by direct protein-protein interactions: insights from snapin and ric8a

artículo científico publicado en 2009

Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease

artículo científico publicado en 2011

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

artículo científico publicado en 2011

Presence of Na+/Ca2+ exchange activity and its role in regulation of intracellular calcium concentration in bovine adrenal chromaffin cells

artículo científico publicado en 1992

Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response

artículo científico publicado en 1997

Protein kinase C inhibits type VI adenylyl cyclase by phosphorylating the regulatory N domain and two catalytic C1 and C2 domains.

artículo científico publicado en 2002

Regulation of P-glycoprotein expression in brain capillaries in Huntington's disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone

artículo científico publicado en 2015

Regulation of adenylyl cyclase in the central nervous system.

artículo científico publicado en 2000

Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease

artículo científico publicado en 2012

Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor

artículo científico publicado en 2007

Regulation of type VI adenylyl cyclase by Snapin, a SNAP25-binding protein

artículo científico publicado en 2004

Spt4 is selectively required for transcription of extended trinucleotide repeats

artículo científico publicado en 2012

Structural role of amino acids 99-110 in recombinant human erythropoietin

artículo científico publicado en 1991

Supraspinal contribution to splanchnic sympathetic activity in neonatal mouse and rat brainstem-spinal cord in vitro

artículo científico publicado en 2010

Systematic uncovering of multiple pathways underlying the pathology of Huntington disease by an acid-cleavable isotope-coded affinity tag approach

artículo científico publicado en 2007

Targeting glial cells to elucidate the pathogenesis of Huntington's disease.

artículo científico publicado en 2010

The 5' untranslated regions of the rat A2A adenosine receptor gene function as negative translational regulators.

artículo científico publicado en 1999

The A2A adenosine receptor is a dual coding gene: a novel mechanism of gene usage and signal transduction.

artículo científico publicado en 2013

The A2A adenosine receptor rescues neuritogenesis impaired by p53 blockage via KIF2A, a kinesin family member

artículo científico publicado en 2010

The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system

artículo científico publicado en 2009

The adenosine analogue N6-L-phenylisopropyladenosine inhibits catecholamine secretion from bovine adrenal medulla cells by inhibiting calcium influx

artículo científico publicado en 1992

The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease

artículo científico publicado en 2011

The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity.

artículo científico publicado en 2014

Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning

artículo científico publicado en 2016

Type VI adenylyl cyclase regulates neurite extension by binding to Snapin and Snap25

scientific journal article

cAMP-response element-binding protein contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues

artículo científico publicado en 2005