Lista de obras - Gregory L. Challis - Dominio Público Uruguay

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining ⬇️

artículo científico publicado en 2008

A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors.

artículo científico publicado en 2016

A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

artículo científico publicado en 2012

A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols

artículo científico publicado en 2010

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics. ⬇️

artículo científico publicado en 2014

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units

artículo científico publicado en 2016

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

artículo científico publicado en 2019

A new family of ATP-dependent oligomerization-macrocyclization biocatalysts

artículo científico publicado en 2007

A novel streptococcal integrative conjugative element involved in iron acquisition.

artículo científico publicado en 2008

A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases

artículo científico publicado en 2005

AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

artículo científico publicado en 2009

An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics

artículo científico publicado en 2019

Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes ⬇️

artículo científico publicado en 2001

Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.

artículo científico publicado en 2017

Antimalarial activity of natural and synthetic prodiginines

artículo científico publicado en 2011

Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC

artículo científico publicado en 2018

Bisucaberin biosynthesis: an adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine

artículo científico publicado en 2008

Chapter 17. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine

artículo científico publicado en 2009

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins ⬇️

artículo científico publicado en 2010

Chemical Biotechnology: bioactive small molecules—targets and discovery technologies

Concise Synthesis of Key 3-Polyenoyl-5-methylenefuran-2,4-dione Putative Intermediates in Quartromicin Biosynthesis

Correction: Unique post-translational oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from sp. FXJ1.264

Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis ⬇️

artículo científico publicado en 2013

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

artículo científico publicado en 2012

Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC.

artículo científico publicado en 2018

Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal

artículo científico publicado en 2020

Discovery and Biosynthesis of Bolagladins: Unusual Lipodepsipeptides from Burkholderia gladioli Clinical Isolates** ⬇️

artículo científico publicado en 2020

Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis ⬇️

artículo científico publicado en 2017

Discovery and biosynthesis of bolagladins: unusual lipodepsipeptides from Burkholderia gladioli clinical isolates

artículo científico publicado en 2020

Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster. ⬇️

artículo científico publicado en 2016

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

artículo científico publicado en 2005

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

artículo científico

Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

artículo científico publicado en 2021

Distinct extracytoplasmic siderophore binding proteins recognize ferrioxamines and ferricoelichelin in Streptomyces coelicolor A3(2).

artículo científico publicado en 2010

Editorial: Biosynthetic assembly lines themed issue.

artículo científico publicado en 2016

Editorial: Fungal natural products themed issue

artículo científico publicado en 2014

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis

artículo científico publicado en 2008

Elucidation of the Streptomyces coelicolor pathway to 4-methoxy-2,2′-bipyrrole-5-carboxaldehyde, an intermediate in prodiginine biosynthesis

artículo científico publicado en 2006

Enacyloxins Are Products of an Unusual Hybrid Modular Polyketide Synthase Encoded by a Cryptic Burkholderia ambifaria Genomic Island

artículo científico publicado en 2011

Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA.

artículo científico publicado en 2009

Engineering Escherichia coli to produce nonribosomal peptide antibiotics

artículo científico publicado en 2006

Engineering p-hydroxyphenylpyruvate dioxygenase to a p-hydroxymandelate synthase and evidence for the proposed benzene oxide intermediate in homogentisate formation

artículo científico publicado en 2004

Enzymatic Logic of Anthrax Stealth Siderophore Biosynthesis: AsbA Catalyzes ATP-Dependent Condensation of Citric Acid and Spermidine

artículo científico publicado en 2007

Erratum: A new family of ATP-dependent oligomerization-macrocyclization biocatalysts

scholarly article published in Nature Chemical Biology

Evidence for the Unusual Condensation of a Diketide with a Pentulose in the Methylenomycin Biosynthetic Pathway of Streptomyces coelicolor A3(2)

article

Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways ⬇️

artículo científico publicado en 2013

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor.

artículo científico publicado en 2008

Functional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracis

artículo científico publicado en 2012

Genome mining for novel natural product discovery

scientific article published on 05 April 2008

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

article

Genome mining of Streptomyces ambofaciens. ⬇️

artículo científico publicado en 2013

Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery

artículo científico publicado en 2020

Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery

artículo científico publicado en 2020

Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

artículo científico publicado en 2009

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei

artículo científico publicado en 2004

Genomics-driven discovery of a novel glutarimide antibiotic from Burkholderia gladioli reveals an unusual polyketide synthase chain release mechanism ⬇️

scientific article published on 12 September 2020

Heavy Tools for Genome Mining

scientific article published on 01 January 2007

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens ⬇️

artículo científico publicado en 2011

Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

artículo científico publicado en 2004

Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-hydroxy-N-succinylputrescine

artículo científico publicado en 2008

In Vitro Biosynthetic Studies of Bottromycin Expand the Enzymatic Capabilities of the YcaO Superfamily

artículo científico publicado en 2017

Kill and cure: genomic phylogeny and bioactivity of bacteria capable of pathogenic and beneficial lifestyles

artículo científico publicado en 2021

LC-MS-Guided Isolation of Penicilfuranone A: A New Antifibrotic Furancarboxylic Acid from the Plant Endophytic Fungus Penicillium sp. sh18.

artículo científico publicado en 2015

MbtH-like protein-mediated cross-talk between non-ribosomal peptide antibiotic and siderophore biosynthetic pathways in Streptomyces coelicolor M145

artículo científico publicado en 2007

Mechanism and Catalytic Diversity of Rieske Non-Heme Iron-Dependent Oxygenases

artículo científico publicado en 2013

Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases

artículo científico publicado en 2018

Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

artículo científico publicado en 2005

Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis

artículo científico publicado en 2016

Microbiology: a talented genus.

artículo científico publicado en 2014

Mining microbial genomes for new natural products and biosynthetic pathways

scientific article published on 01 June 2008

MmfL catalyses formation of a phosphorylated butenolide intermediate in methylenomycin furan biosynthesis

artículo científico publicado en 2020

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

artículo científico publicado en 2006

Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products

artículo científico publicado en 2014

New natural product biosynthetic chemistry discovered by genome mining

artículo científico publicado en 2009

Oxidative tailoring reactions catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example

artículo científico publicado en 2012

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

artículo científico publicado en 2003

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group ⬇️

artículo científico publicado en 2019

Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative

artículo científico publicado en 2008

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

article

Protein-protein interactions in trans-AT polyketide synthases

artículo científico publicado en 2018

Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase

artículo científico publicado en 2008

Recent advances in siderophore biosynthesis

artículo científico publicado en 2009

Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes

artículo científico publicado en 2011

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

artículo científico publicado en 2013

Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis

artículo científico publicado en 2018

Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis

artículo científico publicado en 2008

SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone.

artículo científico publicado en 2015

Stereochemical elucidation of streptorubin B.

artículo científico publicado en 2010

Stereochemistry and Mechanism of Undecylprodigiosin Oxidative Carbocyclization to Streptorubin B by the Rieske Oxygenase RedG

artículo científico publicado en 2015

Strategies for the discovery of new natural products by genome mining

artículo científico publicado en 2009

Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme AcsD

artículo científico publicado en 2011

Structural aspects of non-ribosomal peptide biosynthesis

artículo científico publicado en 2004

Structural basis for chain release from the enacyloxin polyketide synthase

artículo científico publicado en 2019

Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins

scientific article published on 28 February 2012

Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces coelicolor

artículo científico publicado en 2011

Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22. ⬇️

artículo científico publicado en 2013

Structure, Chemical Synthesis, and Biosynthesis of Prodiginine Natural Products

artículo científico publicado en 2016

Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity

artículo científico publicado en 2021

Tailoring reactions catalyzed by heme-dependent enzymes: spectroscopic characterization of the L-tryptophan-nitrating cytochrome P450 TxtE.

artículo científico

The Scottish Structural Proteomics Facility: targets, methods and outputs

artículo científico publicado en 2010

The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.

artículo científico publicado en 2006

The dynamic architecture of the metabolic switch in Streptomyces coelicolor.

artículo científico publicado en 2010

The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin

artículo científico publicado en 2012

The long-overlooked enzymology of a nonribosomal peptide synthetase-independent pathway for virulence-conferring siderophore biosynthesis

scientific article published on 14 September 2009

The plant pathogen Streptomyces scabies 87-22 has a functional pyochelin biosynthetic pathway that is regulated by TetR- and AfsR-family proteins

article

The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus

artículo científico publicado en 2011

The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: their expression in other genera requires ECF sigma factor RpoI.

artículo científico publicado en 2002

Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis

artículo científico publicado en 2016

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining ⬇️

artículo científico publicado en 2006

Understanding biosynthetic protein-protein interactions

artículo científico publicado en 2018

Unique post-translational oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from Streptomyces sp. FXJ1.264 ⬇️

artículo científico publicado en 2015

Unusual odd-electron fragments from even-electron protonated prodiginine precursors using positive-ion electrospray tandem mass spectrometry

artículo científico publicado en 2008

Watasemycin biosynthesis in Streptomyces venezuelae: thiazoline C-methylation by a type B radical-SAM methylase homologue ⬇️

artículo científico publicado en 2017

Lista de obras de Gregory L. Challis

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining ⬇️

A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors.

A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics. ⬇️

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

A new family of ATP-dependent oligomerization-macrocyclization biocatalysts

A novel streptococcal integrative conjugative element involved in iron acquisition.

A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases

AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics

Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes ⬇️

Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.

Antimalarial activity of natural and synthetic prodiginines

Binding of Distinct Substrate Conformations Enables Hydroxylation of Remote Sites in Thaxtomin D by Cytochrome P450 TxtC

Bisucaberin biosynthesis: an adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine

Chapter 17. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins ⬇️

Chemical Biotechnology: bioactive small molecules—targets and discovery technologies

Concise Synthesis of Key 3-Polyenoyl-5-methylenefuran-2,4-dione Putative Intermediates in Quartromicin Biosynthesis

Correction: Unique post-translational oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from sp. FXJ1.264

Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis ⬇️

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC.

Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal

Discovery and Biosynthesis of Bolagladins: Unusual Lipodepsipeptides from Burkholderia gladioli Clinical Isolates** ⬇️

Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis ⬇️

Discovery and biosynthesis of bolagladins: unusual lipodepsipeptides from Burkholderia gladioli clinical isolates

Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster. ⬇️

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

Distinct extracytoplasmic siderophore binding proteins recognize ferrioxamines and ferricoelichelin in Streptomyces coelicolor A3(2).

Editorial: Biosynthetic assembly lines themed issue.

Editorial: Fungal natural products themed issue

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis

Elucidation of the Streptomyces coelicolor pathway to 4-methoxy-2,2′-bipyrrole-5-carboxaldehyde, an intermediate in prodiginine biosynthesis

Enacyloxins Are Products of an Unusual Hybrid Modular Polyketide Synthase Encoded by a Cryptic Burkholderia ambifaria Genomic Island

Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA.

Engineering Escherichia coli to produce nonribosomal peptide antibiotics

Engineering p-hydroxyphenylpyruvate dioxygenase to a p-hydroxymandelate synthase and evidence for the proposed benzene oxide intermediate in homogentisate formation

Enzymatic Logic of Anthrax Stealth Siderophore Biosynthesis: AsbA Catalyzes ATP-Dependent Condensation of Citric Acid and Spermidine

Erratum: A new family of ATP-dependent oligomerization-macrocyclization biocatalysts

Evidence for the Unusual Condensation of a Diketide with a Pentulose in the Methylenomycin Biosynthetic Pathway of Streptomyces coelicolor A3(2)

Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways ⬇️

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production in Streptomyces coelicolor.

Functional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracis

Genome mining for novel natural product discovery

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

Genome mining of Streptomyces ambofaciens. ⬇️

Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery

Genomic Assemblies of Members of and Related Genera as a Resource for Natural Product Discovery

Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei

Genomics-driven discovery of a novel glutarimide antibiotic from Burkholderia gladioli reveals an unusual polyketide synthase chain release mechanism ⬇️

Heavy Tools for Genome Mining

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens ⬇️

Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-hydroxy-N-succinylputrescine

In Vitro Biosynthetic Studies of Bottromycin Expand the Enzymatic Capabilities of the YcaO Superfamily

Kill and cure: genomic phylogeny and bioactivity of bacteria capable of pathogenic and beneficial lifestyles

LC-MS-Guided Isolation of Penicilfuranone A: A New Antifibrotic Furancarboxylic Acid from the Plant Endophytic Fungus Penicillium sp. sh18.

MbtH-like protein-mediated cross-talk between non-ribosomal peptide antibiotic and siderophore biosynthetic pathways in Streptomyces coelicolor M145

Mechanism and Catalytic Diversity of Rieske Non-Heme Iron-Dependent Oxygenases

Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases

Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites

Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis

Microbiology: a talented genus.

Mining microbial genomes for new natural products and biosynthetic pathways

MmfL catalyses formation of a phosphorylated butenolide intermediate in methylenomycin furan biosynthesis

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products

New natural product biosynthetic chemistry discovered by genome mining

Oxidative tailoring reactions catalyzed by nonheme iron-dependent enzymes: streptorubin B biosynthesis as an example

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group ⬇️

Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains