Lista de obras - José C Fernández-Checa

A simple technique to determine glutathione (GSH) levels and synthesis in ocular tissues as GSH-bimane adduct: application to normal and galactosemic guinea-pigs.

artículo científico publicado en 1993

APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.

artículo científico publicado en 2013

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

artículo científico publicado en 2013

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

artículo científico publicado en 2014

Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress

artículo científico publicado en 2003

Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways

artículo científico

Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis

artículo científico publicado en 2010

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

artículo científico publicado en 2004

Alcohol, signaling, and ECM turnover.

artículo científico publicado en 2009

Alcohol-induced liver disease: from molecular damage to treatment.

artículo científico publicado en 2002

Alcohol-induced liver disease: when fat and oxidative stress meet.

artículo científico publicado en 2003

Alcoholic liver disease

scientific article published on 01 January 1996

Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001.

artículo científico publicado en 2002

Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer

artículo científico publicado en 2015

Augmenter of liver regeneration links mitochondrial function to steatohepatitis and hepatocellular carcinoma

artículo científico publicado en 2014

Bidirectional mechanism of plasma membrane transport of reduced glutathione in intact rat hepatocytes and membrane vesicles

artículo científico publicado en 1992

Brain mitochondrial alterations after chronic alcohol consumption.

artículo científico publicado en 2009

Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats ⬇️

artículo científico publicado el 25 de enero de 1992

Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease

artículo científico publicado en 2011

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

artículo científico publicado en 2009

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

artículo científico publicado en 2011

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation

artículo científico publicado en 2002

Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells. ⬇️

artículo científico publicado en 2015

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

artículo científico publicado en 2010

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

scientific journal article

Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

artículo científico publicado en 1998

Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury

artículo científico publicado en 2006

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

artículo científico publicado en 2004

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

artículo científico publicado en 2011

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

artículo científico publicado en 2016

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

artículo científico publicado en 2003

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential modulation of interleukin 8 by interleukin 4 and interleukin 10 in HepG2 cells treated with acetaldehyde.

artículo científico publicado en 2005

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

artículo científico publicado en 1997

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells

artículo científico publicado en 2002

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

article

Editorial [Hot Topic: Lipids in Cancer Cell Biology and Therapy Guest Editor: Jose C. Fernandez-Checa)]

artículo científico publicado en 2012

Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: studies in isolated hepatocytes and perfused rat liver

artículo científico publicado en 1991

Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes

artículo científico publicado en 1988

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

artículo científico publicado en 1998

Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking

artículo científico publicado en 2014

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH.

artículo científico publicado en 2009

Evidence that interference with binding to hepatic cytosol binders can inhibit bile acid excretion in rats

article

Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytes

artículo científico publicado en 1995

Expression cloning of the cDNA for a polypeptide associated with rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter.

artículo científico publicado en 1995

Expression of rat liver reduced glutathione transport in Xenopus laevis oocytes

artículo científico publicado en 1993

Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

artículo científico publicado en 1995

Functional properties of isolated hepatocytes from ethanol-treated rat liver

artículo científico publicado en 1985

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

artículo científico publicado en 1997

GSH transporters: molecular characterization and role in GSH homeostasis

artículo científico publicado en 1996

Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy

artículo científico publicado en 2002

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

artículo científico publicado en 2015

Gastric mucosal damage in experimental diabetes in rats: Role of endogenous glutathione

artículo científico publicado en 1997

Glutathione and mitochondria

artículo científico publicado en 2014

Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activation

artículo científico publicado en 2004

Glycosphingolipids and cell death: one aim, many ways

artículo científico publicado en 2015

Glycosphingolipids and mitochondria: role in apoptosis and disease.

artículo científico publicado en 2004

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.

artículo científico publicado en 2010

Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

artículo científico publicado en 1992

Hepatic mitochondrial glutathione: transport and role in disease and toxicity.

artículo científico publicado en 2005

Hepatocellular oxidative stress and initial graft injury in human liver transplantation

artículo científico publicado en 1999

How is the liver primed or sensitized for alcoholic liver disease?

artículo científico publicado en 2001

Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.

artículo científico publicado en 2001

Increased tumour necrosis factor‐α plasma levels during moderate-intensity exercise in COPD patients

artículo científico publicado en 2003

Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin. Kinetics, sidedness, and molecular forms

artículo científico publicado en 1988

Inhibition of rat sinusoidal GSH transporter by thioethers: specificity, sidedness, and kinetics

artículo científico publicado en 1996

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

artículo científico publicado en 2014

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

artículo científico publicado en 2016

Liver and lens glutathione and cysteine regulation in galactose-fed guinea pigs

artículo científico publicado en 1997

Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy

artículo científico publicado en 2015

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

artículo científico publicado en 2017

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

artículo científico publicado en 2008

Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy

artículo científico publicado en 2016

Metabolic therapy: lessons from liver diseases.

artículo científico

Mitochondria, cholesterol and amyloid beta peptide: a dangerous trio in Alzheimer disease.

artículo científico publicado en 2009

Mitochondria, cholesterol and cancer cell metabolism

artículo científico publicado en 2016

Mitochondrial Cholesterol and the Paradox in Cell Death

artículo científico publicado en 2016

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

artículo científico publicado en 2012

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

artículo científico publicado en 2016

Mitochondrial Glutathione: Importance and Transport

article

Mitochondrial S-adenosyl-L-methionine transport is insensitive to alcohol-mediated changes in membrane dynamics.

artículo científico publicado en 2009

Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.

artículo científico publicado en 2014

Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.

artículo científico publicado en 2008

Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity

artículo científico publicado en 2009

Mitochondrial cholesterol: a connection between caveolin, metabolism, and disease

artículo científico

Mitochondrial dysfunction in COPD patients with low body mass index

artículo científico publicado en 2006

Mitochondrial glutathione depletion in alcoholic liver disease

artículo científico publicado en 1993

Mitochondrial glutathione, a key survival antioxidant

artículo científico publicado en 2009

Mitochondrial glutathione: features, regulation and role in disease

artículo científico publicado en 2013

Mitochondrial permeability transition induced by reactive oxygen species is independent of cholesterol-regulated membrane fluidity

artículo científico publicado en 2004

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis

artículo científico publicado en 2015

Neutral sphingomyelinase-induced ceramide triggers germinal vesicle breakdown and oxidant-dependent apoptosis in Xenopus laevis oocytes

artículo científico publicado en 2007

Oxidative damage of mitochondrial and nuclear DNA induced by ionizing radiation in human hepatoblastoma cells

artículo científico publicado en 1998

Oxidative stress and alcoholic liver disease.

artículo científico publicado en 1997

Oxidative stress: role of mitochondria and protection by glutathione

artículo científico publicado en 1998

PGE1 protection against apoptosis induced by D-galactosamine is not related to the modulation of intracellular free radical production in primary culture of rat hepatocytes

artículo científico publicado en 2002

Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo

article

Pharmacological modulation of sphingolipids and role in disease and cancer cell biology.

artículo científico publicado en 2007

Plasma membrane and mitochondrial transport of hepatic reduced glutathione

artículo científico publicado en 1996

Probiotic sonicates selectively induce mucosal immune cells apoptosis through ceramide generation via neutral sphingomyelinase

artículo científico publicado en 2011

Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice

artículo científico publicado en 2017

Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process

artículo científico publicado en 1997

Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/reperfusion

artículo científico publicado en 2009

Redox control of liver function in health and disease

artículo científico publicado en 2010

Redox regulation and signaling lipids in mitochondrial apoptosis ⬇️

artículo científico publicado el 9 de mayo de 2003

Redox regulation of hepatocyte apoptosis

artículo científico publicado en 2007

Reduced muscle redox capacity after endurance training in patients with chronic obstructive pulmonary disease

artículo científico publicado en 2001

Reply

Role of Mitochondria in Alcoholic Liver Disease

artículo científico publicado en 2013

Role of apoptosis in alcoholic liver injury

artículo científico publicado en 2003

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondri

artículo científico publicado en 1995

S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease

artículo científico publicado en 2002

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity

artículo científico publicado en 2015

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

artículo científico publicado en 1998

Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles.

artículo científico publicado en 1993

Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.

artículo científico publicado en 2010

Sphingolipid signalling and liver diseases

artículo científico publicado en 2007

Sphingolipids and cell death.

artículo científico publicado en 2007

Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis

artículo científico publicado en 2020

Statins and Protein Prenylation in Cancer Cell Biology and Therapy ⬇️

artículo científico publicado el 1 de mayo de 2012

Systemic effects of cigarette smoke exposure in the guinea pig.

artículo científico publicado en 2005

Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia–reperfusion injury

scientific article published on 29 October 2010

Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma

artículo científico publicado en 2016

Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione.

artículo científico publicado en 2001

The fluidity of liver plasma membranes from patients with different types of liver injury

artículo científico publicado en 1986

The use of monochlorobimane to determine hepatic GSH levels and synthesis

artículo científico publicado en 1990

To binge or not to binge: binge drinking disrupts glucose homeostasis by impairing hypothalamic but not liver insulin signaling

artículo científico publicado en 2013

Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha

scientific journal article

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

artículo científico publicado en 1998

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol-treated rats: Effect of membrane physical properties andS-adenosyl-L-methionine

artículo científico publicado en 1997

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

artículo científico publicado en 1997

VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis

artículo científico publicado en 1999

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de José C Fernández-Checa

A simple technique to determine glutathione (GSH) levels and synthesis in ocular tissues as GSH-bimane adduct: application to normal and galactosemic guinea-pigs.

APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease.

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress

Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways

Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis

Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis

Alcohol, signaling, and ECM turnover.

Alcohol-induced liver disease: from molecular damage to treatment.

Alcohol-induced liver disease: when fat and oxidative stress meet.

Alcoholic liver disease

Alcoholic liver injury and apoptosis--synopsis of the symposium held at ESBRA 2001: 8th Congress of the European Society for Biomedical Research on Alcoholism, Paris, September 16, 2001.

Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer

Augmenter of liver regeneration links mitochondrial function to steatohepatitis and hepatocellular carcinoma

Bidirectional mechanism of plasma membrane transport of reduced glutathione in intact rat hepatocytes and membrane vesicles

Brain mitochondrial alterations after chronic alcohol consumption.

Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats ⬇️

Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility.

Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-α-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation

Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells. ⬇️

Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death

Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity

Chronic Ethanol Feeding Induces Cellular Antioxidants Decrease and Oxidative Stress in Rat Peripheral Nerves. Effect of S-Adenosyl-l-Methionine and N-Acetyl-l-Cysteine

Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury

Critical role of mitochondrial glutathione in the survival of hepatocytes during hypoxia

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Defective TNF-α–mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice

Differential modulation of interleukin 8 by interleukin 4 and interleukin 10 in HepG2 cells treated with acetaldehyde.

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

Editorial [Hot Topic: Lipids in Cancer Cell Biology and Therapy Guest Editor: Jose C. Fernandez-Checa)]

Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: studies in isolated hepatocytes and perfused rat liver

Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH.

Evidence that interference with binding to hepatic cytosol binders can inhibit bile acid excretion in rats

Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytes

Expression cloning of the cDNA for a polypeptide associated with rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter.

Expression of rat liver reduced glutathione transport in Xenopus laevis oocytes

Feeding S-adenosyl-L-methionine attenuates both ethanol-induced depletion of mitochondrial glutathione and mitochondrial dysfunction in periportal and perivenous rat hepatocytes

Functional properties of isolated hepatocytes from ethanol-treated rat liver

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

GSH transporters: molecular characterization and role in GSH homeostasis

Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy

Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation

Gastric mucosal damage in experimental diabetes in rats: Role of endogenous glutathione

Glutathione and mitochondria

Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activation

Glycosphingolipids and cell death: one aim, many ways

Glycosphingolipids and mitochondria: role in apoptosis and disease.

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury.

Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

Hepatic mitochondrial glutathione: transport and role in disease and toxicity.

Hepatocellular oxidative stress and initial graft injury in human liver transplantation

How is the liver primed or sensitized for alcoholic liver disease?

Identification and functional analysis of mutations in FAD-binding domain of mitochondrial glycerophosphate dehydrogenase in caucasian patients with type 2 diabetes mellitus.

Increased tumour necrosis factor‐α plasma levels during moderate-intensity exercise in COPD patients

Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin. Kinetics, sidedness, and molecular forms

Inhibition of rat sinusoidal GSH transporter by thioethers: specificity, sidedness, and kinetics

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

Liver and lens glutathione and cysteine regulation in galactose-fed guinea pigs

Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.

Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy

Metabolic therapy: lessons from liver diseases.

Mitochondria, cholesterol and amyloid beta peptide: a dangerous trio in Alzheimer disease.

Mitochondria, cholesterol and cancer cell metabolism

Mitochondrial Cholesterol and the Paradox in Cell Death

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis.

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.