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Lista de obras de Jean-Sébastien Hulot

2013 ESC guidelines on the management of stable coronary artery disease

scientific article published on 30 August 2013

A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

artículo científico publicado en 2017

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.

artículo científico publicado en 2013

An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.

artículo científico publicado en 2013

Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes

artículo científico publicado en 2019

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

artículo científico publicado en 2022

Anti-integrin αv therapy improves cardiac fibrosis after myocardial infarction by blunting cardiac PW1+ stromal cells

artículo científico publicado en 2020

Antilipemics and prevention of cerebrovascular accidents. Meta-analysis

artículo científico publicado en 2003

Antiplatelet Therapy and Coronary Artery Bypass Graft Surgery

artículo científico publicado en 2010

Antiplatelet and anticoagulation therapy for acute coronary syndromes

artículo científico publicado en 2014

Antiplatelet drug interactions with proton pump inhibitors

artículo científico publicado en 2013

Antiplatelet therapy: Personalized medicine for clopidogrel resistance?

artículo científico publicado en 2009

Arrhythmogenic right ventricular dysplasia and sudden cardiac death

artículo científico publicado en 2005

Assessment of signal quality measured with a smart 12-lead ECG acquisition T-shirt

artículo científico publicado en 2019

Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.

artículo científico publicado en 2006

Association of Oral Contraceptives With Drug-Induced QT Interval Prolongation in Healthy Nonmenopausal Women

artículo científico publicado en 2018

Avancées récentes et perspectives dans le traitement des dyslipidémies athérogènes

artículo científico publicado en 2007

Beta-blocker benefit according to severity of heart failure.

artículo científico publicado en 2003

Beta-blocker treatment in heart failure.

artículo científico publicado en 2001

Blockbuster interactions: are they bad for the patient?

artículo científico publicado en 2012

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

artículo científico publicado en 2021

CRISPR/Cas9 gene-editing strategies in cardiovascular cells

artículo científico publicado en 2020

CRISPRed Cardiomyocytes to Decrypt Variants of Uncertain Significance ∗

artículo científico publicado en 2018

CYP2C19 But Not PON1 Genetic Variants Influence Clopidogrel Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy in Post–Myocardial Infarction Patients

artículo científico publicado en 2011

Can we override clopidogrel resistance?

artículo científico publicado en 2009

Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling

artículo científico publicado en 2016

Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR- and Orai3- dependent signaling

artículo científico publicado en 2019

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

artículo científico publicado en 2014

Cardiomyocyte-Specific STIM1 (Stromal Interaction Molecule 1) Depletion in the Adult Heart Promotes the Development of Arrhythmogenic Discordant Alternans

artículo científico publicado en 2019

Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis

artículo científico publicado en 2010

Changes in enoxaparin pharmacokinetics during pregnancy and implications for antithrombotic therapeutic strategy

artículo científico publicado en 2008

Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update.

artículo científico publicado en 2013

Clinical implications of neuropharmacogenetics.

artículo científico

Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis

artículo científico publicado en 2011

Clopidogrel and CYP2C19 Testing: Ready for Clinical Prime Time?

artículo científico publicado en 2011

Clopidogrel and CYP2C19: pharmacogenetic testing ready for clinical prime time?

artículo científico publicado en 2015

Clustering of acute and subacute stent thrombosis related to the introduction of generic clopidogrel

artículo científico publicado en 2013

Combination of B-type natriuretic peptide and peak oxygen consumption improves risk stratification in outpatients with chronic heart failure

artículo científico publicado en 2003

Comparison of echocardiography and plasma B-type natriuretic peptide for monitoring the response to treatment in acute heart failure

artículo científico publicado en 2004

Complex Association of Sex Hormones on Left Ventricular Systolic Function: Insight into Sexual Dimorphism

artículo científico publicado en 2017

Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes

artículo científico publicado en 2014

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy

artículo científico publicado en 2015

Cyclic nucleotide compartmentalization: contributions of phosphodiesterases and ATP-binding cassette transporters.

artículo científico publicado en 2012

Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects

artículo científico publicado en 2006

Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

artículo científico publicado en 2008

Cytotoxic CD8<sup>+</sup> T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling

artículo científico publicado en 2021

Design and Validation of an Automated Process for the Expansion of Peripheral Blood-Derived CD34+ Cells for Clinical Use After Myocardial Infarction

scientific article published on 29 April 2019

Determinants of hydroxychloroquine blood concentration variations in systemic lupus erythematosus

artículo científico publicado en 2015

Development and validation of a rapid and simple LC-MS/MS method for quantification of vemurafenib in human plasma: application to a human pharmacokinetic study.

artículo científico publicado en 2015

Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols

artículo científico publicado en 2017

Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

artículo científico publicado en 2021

Dosing strategy in patients with renal failure receiving enoxaparin for the treatment of non-ST-segment elevation acute coronary syndrome

artículo científico publicado en 2005

Downregulation of the calcium current in human right atrial myocytes from patients in sinus rhythm but with a high risk of atrial fibrillation.

artículo científico publicado en 2008

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

artículo científico publicado en 2019

Effect of an increased clopidogrel maintenance dose or lansoprazole co-administration on the antiplatelet response to clopidogrel in CYP2C19-genotyped healthy subjects

artículo científico publicado en 2009

Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT-HF randomized phase 2 trial

artículo científico publicado en 2017

Effect of renal function on the pharmacokinetics of enoxaparin and consequences on dose adjustment

artículo científico publicado en 2004

Effectiveness of gene delivery systems for pluripotent and differentiated cells.

artículo científico publicado en 2015

Effectiveness of heart rate control on hemodynamics in critically ill patients with atrial tachyarrhythmias managed by amiodarone

scholarly article by Joe-Elie Salem et al published August 2017 in Pharmacological Research

Emergence of Orai3 activity during cardiac hypertrophy.

artículo científico publicado en 2014

Emerging Drug Classes and Their Potential Use in Hypertension

scientific article published on 09 September 2019

Exome sequencing of extreme clopidogrel response phenotypes identifies B4GALT2 as a determinant of on-treatment platelet reactivity

artículo científico publicado en 2016

Faut-il doser l'hydroxychloroquine chez les patients lupiques ?

artículo científico publicado en 2006

Feasibility and safety of ultrasound-aided thoracentesis in mechanically ventilated patients

artículo científico publicado en 1999

Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells

artículo científico publicado en 2017

Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.

artículo científico publicado en 2017

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, "GENEREPOL study": Lack of common variants with large effect sizes.

artículo científico publicado en 2017

Gene therapy for the treatment of heart failure: promise postponed

artículo científico publicado en 2016

Generating patient-specific induced pluripotent stem cells-derived cardiomyocytes for the treatment of cardiac diseases

artículo científico

Genetic and platelet function testing of antiplatelet therapy for percutaneous coronary intervention: the ARCTIC-GENE study

artículo científico publicado en 2015

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy

artículo científico publicado en 2009

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).

artículo científico publicado en 2017

Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.

artículo científico publicado en 2016

Get Your Cell K.O. in the First Round

artículo científico publicado en 2017

Heart conduction disorders related to antimalarials toxicity: an analysis of electrocardiograms in 85 patients treated with hydroxychloroquine for connective tissue diseases

artículo científico publicado en 2007

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology

artículo científico publicado en 2018

High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study

artículo científico publicado en 2011

Hydroxychloroquine in systemic lupus erythematosus

artículo científico publicado en 2007

Hydroxychloroquine in systemic lupus erythematosus: results of a French multicentre controlled trial (PLUS Study).

artículo científico publicado en 2012

Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy

artículo científico publicado en 2012

Impact of Inodilator Drugs on Echocardiographic Assessments of Left Ventricular Filling Pressure in Patients With Decompensated End-Stage Heart Failure*

artículo científico publicado en 2014

Impact of negative inotropic drugs on accuracy of diastolic stress echocardiography for evaluation of left ventricular filling pressure

artículo científico

Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice.

artículo científico publicado en 2015

In Vitro Adherence Defines Therapeutic Cardiac Mesenchymal Cell Subpopulation ∗

artículo científico publicado en 2017

Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects

artículo científico publicado en 2007

Influence of endogenous oestrogens on QT interval duration

artículo científico publicado en 2003

Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

artículo científico publicado en 2010

Inhalable delivery of AAV-based MRP4/ABCC4 silencing RNA prevents monocrotaline-induced pulmonary hypertension

artículo científico publicado en 2015

Intravenous Clopidogrel (MDCO-157) Compared with Oral Clopidogrel: The Randomized Cross-Over AMPHORE Study

artículo científico

Long-Term Evolution of Premature Coronary Artery Disease

scientific article published on 01 October 2019

Low blood concentration of hydroxychloroquine is a marker for and predictor of disease exacerbations in patients with systemic lupus erythematosus

artículo científico publicado en 2006

Lower vitamin D levels are associated with higher systemic lupus erythematosus activity, but not predictive of disease flare-up

artículo científico publicado en 2014

MRP4 (ABCC4) as a potential pharmacologic target for cardiovascular disease.

artículo científico publicado en 2016

Modeling CVD in human pluripotent cells by genome editing

artículo científico publicado en 2014

Modeling Cardiac Arrhythmias With Organoids

artículo científico publicado en 2019

Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients with Atrial Tachyarrhythmias

artículo científico publicado en 2016

Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells

artículo científico publicado en 2017

Multi-ethnic distribution of clinically relevant CYP2C genotypes and haplotypes.

artículo científico publicado en 2012

Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation

artículo científico publicado en 2008

Mycophenolic acid area under the curve correlates with disease activity in lupus patients treated with mycophenolate mofetil

artículo científico publicado en 2010

Myocardial delivery of stromal cell-derived factor 1 in patients with ischemic heart disease: safe and promising

artículo científico publicado en 2013

Nelfinavir and felodipine: a cytochrome P450 3A4-mediated drug interaction

artículo científico publicado en 2004

Omeprazole, pantoprazole, and CYP2C19 effects on clopidogrel pharmacokinetic-pharmacodynamic relationships in stable coronary artery disease patients

artículo científico publicado en 2015

Opioid-related genetic polymorphisms do not influence postoperative opioid requirement: A prospective observational study.

artículo científico publicado en 2018

Overexpression of Cyclic Adenosine Monophosphate Effluent Protein MRP4 Induces an Altered Response to β-Adrenergic Stimulation in the Senescent Rat Heart

artículo científico publicado en 2015

PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes

article

Perivascular fibrosis and the microvasculature of the heart. Still hidden secrets of pathophysiology?

artículo científico publicado en 2018

PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.

artículo científico publicado en 2012

Pharmacokinetic and pharmacodynamic interactions between metoprolol and dronedarone in extensive and poor CYP2D6 metabolizers healthy subjects.

artículo científico publicado en 2004

Pharmacokinetic study of mycophenolate mofetil in patients with systemic lupus erythematosus and design of Bayesian estimator using limited sampling strategies

artículo científico publicado en 2008

Pharmacology and mechanisms of action of new oral anticoagulants.

artículo científico

Platelet reactivity in human immunodeficiency virus infected patients on dual antiplatelet therapy for an acute coronary syndrome: the EVERE2ST-HIV study

artículo científico publicado en 2017

Point-of-care genetic profiling and/or platelet function testing in acute coronary syndrome.

artículo científico publicado en 2015

Population pharmacokinetic study of methotrexate in patients with lymphoid malignancy

artículo científico publicado en 2006

Population pharmacokinetics of tacrolimus in full liver transplant patients: modelling of the post-operative clearance.

artículo científico publicado en 2005

Potentialisation de la fluindione et de la warfarine par la dexaméthasone dans le myélome multiple et l'amylose AL

artículo científico publicado en 2007

Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis.

artículo científico publicado en 2007

Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: a meta-analysis.

artículo científico publicado en 2007

Quality of life in systemic lupus erythematosus: description in a cohort of French patients and association with blood hydroxychloroquine levels

artículo científico publicado en 2016

Quantification of coproporphyrin isomers I and III in urine by HPLC and determination of their ratio for investigations of multidrug resistance protein 2 (MRP2) function in humans

artículo científico publicado en 2009

RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat.

artículo científico publicado en 2008

Reduced risk of cancer among low-dose aspirin users: Data from French health care databases

scientific article published on 23 July 2019

Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome.

artículo científico publicado en 2018

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

artículo científico publicado en 2011

Relationship between blood hydroxychloroquine and desethylchloroquine concentrations and cigarette smoking in treated patients with connective tissue diseases

artículo científico publicado en 2007

Renal Tubular Drug Transporters

artículo científico publicado en 2006

Renal safety of adefovir dipivoxil in patients with chronic hepatitis B: two double-blind, randomized, placebo-controlled studies

artículo científico publicado en 2004

Renal safety of tenofovir in HIV treatment-experienced patients.

artículo científico publicado en 2004

Resident PW1 + Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension

artículo científico publicado en 2016

Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation

artículo científico publicado en 2008

Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography–tandem mass spectrometry

artículo científico publicado en 2014

Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes.

artículo científico publicado en 2013

Spontaneous renal CT-scan hyperdensity of an HIV-associated nephropathy.

artículo científico publicado en 2003

Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells.

artículo científico publicado en 2012

Stent thrombosis: who's guilty?

artículo científico publicado en 2009

The CLIPMERGE PGx Program: clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics

artículo científico publicado en 2013

The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial

artículo científico publicado en 2011

The CYP2C19*17 allele is associated with better platelet response to clopidogrel in patients admitted for non-ST acute coronary syndrome.

artículo científico publicado en 2009

The continuous heart failure spectrum: moving beyond an ejection fraction classification

scientific article published on 01 July 2019

The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks.

artículo científico publicado en 2018

The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19

artículo científico publicado en 2015

Therapeutic drug monitoring of clozapine in a hemodialysed smoking patient with schizophrenia

artículo científico publicado en 2009

Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.

artículo científico publicado en 2013

Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies

scientific article published on 29 August 2019

Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance

artículo científico publicado en 2014

Use of an indirect effect model to describe the LDL cholesterol-lowering effect by statins in hypercholesterolaemic patients

artículo científico publicado en 2006

Very low blood hydroxychloroquine concentration as an objective marker of poor adherence to treatment of systemic lupus erythematosus

artículo científico publicado en 2007

miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice

artículo científico publicado en 2016

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