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Lista de obras de Erwan Bezard

A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease

artículo científico publicado en 2016

A brain-spine interface alleviating gait deficits after spinal cord injury in primates

artículo científico publicado en 2016

A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism

scientific article published on 01 September 2006

A chronic MPTP model reproducing the slow evolution of Parkinson's disease: evolution of motor symptoms in the monkey

artículo científico publicado en 1997

A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale

artículo científico

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

artículo científico publicado en 2010

A new cerebral hemorrhage model in cynomolgus macaques created by injection of autologous anticoagulated blood into the brain

artículo científico publicado en 2011

A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease.

artículo científico publicado en 2017

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia

artículo científico publicado en 2013

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

artículo científico publicado en 1999

Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice

artículo científico publicado en 2006

Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse

artículo científico publicado en 2000

Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate

artículo científico publicado en 2012

Alpha-synuclein propagation: New insights from animal models

artículo científico

Alterations in Functional Cortical Hierarchy in Hemiparkinsonian Rats.

artículo científico publicado en 2017

Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease

artículo científico publicado en 2005

Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.

artículo científico publicado en 2007

Altered pallido-pallidal synaptic transmission leads to aberrant firing of globus pallidus neurons in a rat model of Parkinson's disease.

artículo científico publicado en 2012

An evaluation of istradefylline treatment on Parkinsonian motor and cognitive deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque models

artículo científico publicado en 2016

An mGlu4-Positive Allosteric Modulator Alleviates Parkinsonism in Primates

artículo científico publicado en 2018

Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.

artículo científico publicado en 2012

Animal models of parkinsonism

artículo científico publicado en 2005

Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3,4-dihydroxyphenylalanine-induced dyskinesia.

artículo científico publicado en 2008

Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

artículo científico publicado en 2013

Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson's disease

artículo científico publicado en 2016

Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?

artículo científico publicado en 2014

Asymmetrically lesioned mesencephalon in healthy rodents: call for caution

artículo científico publicado en 2004

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function

artículo científico publicado en 2003

Basal Ganglia circuits underlying the pathophysiology of levodopa-induced dyskinesia.

artículo científico publicado en 2010

Behavioural profiles in captive-bred cynomolgus macaques: towards monkey models of mental disorders?

artículo científico publicado en 2013

Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function.

artículo científico publicado en 2015

Brain-derived neurotrophic factor and the plasticity of the mesolimbic dopamine pathway

artículo científico publicado en 2004

Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease.

artículo científico publicado en 2003

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease

artículo científico publicado en 2020

Cardinal Motor Features of Parkinson's Disease Coexist with Peak-Dose Choreic-Type Drug-Induced Dyskinesia.

artículo científico publicado en 2018

Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders.

artículo científico publicado en 2009

Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia

artículo científico publicado en 2008

Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease

artículo científico publicado en 2014

Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey

scientific article published on 01 March 2000

Compensatory effects of glutamatergic inputs to the substantia nigra pars compacta in experimental parkinsonism

artículo científico publicado en 1997

Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach

artículo científico publicado en 1998

Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei.

artículo científico publicado en 2003

Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

scientific article published on 23 September 2019

Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics

artículo científico publicado en 2018

Contribution of pre-synaptic mechanisms to L-DOPA-induced dyskinesia.

artículo científico publicado en 2011

Coordinated reset has sustained aftereffects in Parkinsonian monkeys

artículo científico publicado en 2012

Cortical stimulation and epileptic seizure: a study of the potential risk in primates

artículo científico publicado en 1999

Could the serotonin theory give rise to a treatment for levodopa-induced dyskinesia in Parkinson's disease?

artículo científico publicado en 2015

D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly

artículo científico publicado en 2015

D1 dopamine receptor-mediated LTP at GABA synapses encodes motivation to self-administer cocaine in rats

artículo científico publicado en 2013

D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.

artículo científico publicado en 2013

Decreased Rhes mRNA levels in the brain of patients with Parkinson's disease and MPTP-treated macaques

artículo científico publicado en 2017

Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease

artículo científico publicado en 2004

Differential behavioral effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats

artículo científico publicado en 2008

Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections

artículo científico publicado en 2014

Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia

artículo científico publicado en 2010

Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys

artículo científico publicado en 2010

Dopamine-dependent long-term depression at subthalamo-nigral synapses is lost in experimental parkinsonism

artículo científico publicado en 2013

Double-dissociation of the catecholaminergic modulation of synaptic transmission in the oval bed nucleus of the stria terminalis.

artículo científico publicado en 2010

Down-regulating α-synuclein for treating synucleopathies

artículo científico publicado en 2014

Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey

artículo científico publicado en 2015

Effect of serotonin transporter blockade on L-DOPA-induced dyskinesia in animal models of Parkinson's disease

artículo científico publicado en 2015

Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys.

artículo científico publicado en 2004

Effect of the alpha 2 adrenoreceptor antagonist, idazoxan, on motor disabilities in MPTP-treated monkey

artículo científico publicado en 1999

Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey

artículo científico publicado en 1998

Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease

artículo científico publicado en 2014

Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey

artículo científico publicado en 2000

Electrophysiological and metabolic evidence that high‐frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata ⬇️

artículo científico publicado el 1 de octubre de 2003

Endogenous morphine-like compound immunoreactivity increases in parkinsonism

artículo científico publicado en 2011

Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity

artículo científico publicado en 2017

Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

artículo científico publicado en 2006

Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors.

artículo científico publicado en 2003

Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates

scientific article published on 11 May 2020

Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.

artículo científico publicado en 2017

Experimental animal models of Parkinson's disease: A transition from assessing symptomatology to α-synuclein targeted disease modification.

artículo científico publicado en 2017

Experimental models of Parkinson's disease: from the static to the dynamic

artículo científico publicado en 1998

Experimental reappraisal of continuous dopaminergic stimulation against L-dopa-induced dyskinesia

artículo científico publicado en 2012

From experimentation to the surgical treatment of Parkinson's disease: prelude or suite in basal ganglia research?

artículo científico publicado en 1999

Functional connectivity in human and monkey brain: new insights for understanding movement disorders?

artículo científico publicado en 2012

G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice

artículo científico publicado en 2018

Gastrointestinal and metabolic function in the MPTP-treated macaque model of Parkinson's disease

artículo científico publicado en 2020

Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex.

artículo científico publicado en 2010

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.

artículo científico publicado en 2016

Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.

artículo científico publicado en 2017

Glutamatergic compensatory mechanisms in experimental parkinsonism

artículo científico publicado en 1998

Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases

scientific article published on 27 November 2018

Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line

artículo científico publicado en 2015

High frequency stimulation of the entopeduncular nucleus has no effect on striatal dopaminergic transmission

artículo científico publicado en 2004

High frequency stimulation of the entopeduncular nucleus sets the cortico-basal ganglia network to a new functional state in the dystonic hamster

artículo científico publicado en 2009

High frequency stimulation of the internal Globus Pallidus (GPi) simultaneously improves parkinsonian symptoms and reduces the firing frequency of GPi neurons in the MPTP-treated monkey

artículo científico publicado en 1996

High-frequency stimulation of both zona incerta and subthalamic nucleus induces a similar normalization of basal ganglia metabolic activity in experimental parkinsonism

artículo científico publicado en 2004

IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP.

artículo científico publicado en 2008

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

artículo científico publicado en 2020

Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia

artículo científico publicado en 2013

Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson's disease

artículo científico publicado en 2007

Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update.

artículo científico publicado en 2017

In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease.

artículo científico publicado en 2017

In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.

artículo científico publicado en 2017

Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.

artículo científico publicado en 2005

Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine

artículo científico publicado en 2006

Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice

artículo científico publicado en 2020

Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism

scholarly article by Jérôme Baufreton et al published October 2018 in Movement Disorders

Inhibiting Lateral Habenula Improves L-DOPA-Induced Dyskinesia.

artículo científico publicado en 2014

Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms.

artículo científico publicado en 2009

Insulin resistance and exendin-4 treatment for multiple system atrophy.

artículo científico publicado en 2017

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

artículo científico publicado en 2014

Intra-axonal protein aggregation in the peripheral nervous system

artículo científico publicado en 2014

Intrastriatal injection of alpha-synuclein fibrils induces Parkinson-like pathology in macaques

artículo científico publicado en 2019

Intratelencephalic corticostriatal neurons equally excite striatonigral and striatopallidal neurons and their discharge activity is selectively reduced in experimental parkinsonism

artículo científico publicado en 2008

Investigating the receptor-independent neuroprotective mechanisms of nicotine in mitochondria

artículo científico publicado en 2005

Involvement of canonical and non-canonical D1 dopamine receptor signalling pathways in L-dopa-induced dyskinesia.

artículo científico publicado en 2009

Involvement of sensorimotor, limbic, and associative basal ganglia domains in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

artículo científico publicado en 2005

Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia

artículo científico publicado en 2017

Involvement of the subthalamic nucleus in glutamatergic compensatory mechanisms

artículo científico publicado en 1999

Is near-infrared light neuroprotective?

artículo científico publicado en 2016

Kinetics of nigral degeneration in a chronic model of MPTP-treated mice

artículo científico publicado en 1997

L-DOPA Impairs Proteasome Activity in Parkinsonism through D1 Dopamine Receptor

artículo científico publicado en 2012

L-DOPA regulates α-synuclein accumulation in experimental parkinsonism

artículo científico publicado en 2020

L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain

artículo científico publicado en 2005

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

artículo científico publicado en 2014

LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain

artículo científico publicado en 2016

Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.

artículo científico publicado en 2015

Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model

scientific article published on 04 April 2017

Levetiracetam Interferes With the L-dopa priming process in MPTP-lesioned drug-naive marmosets

artículo científico publicado en 2004

Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque

artículo científico publicado en 2004

Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease

artículo científico publicado en 2004

Levodopa gains psychostimulant-like properties after nigral dopaminergic loss

artículo científico publicado en 2013

Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model

artículo científico publicado en 2012

Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.

artículo científico publicado en 2005

Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts

artículo científico publicado en 2018

Levodopa-induced dyskinesias in the absence of nigrostriatal degeneration

artículo científico publicado en 2013

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

artículo científico publicado en 2014

Local transgene expression and whole-body transgenesis to model brain diseases in nonhuman primate

artículo científico publicado en 2019

Localization of endogenous morphine-like compounds in the mouse spinal cord

artículo científico publicado en 2012

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

artículo científico publicado en 2012

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

scientific journal article

Lysosomal impairment in Parkinson's disease

artículo científico publicado en 2013

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

artículo científico publicado en 2014

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

artículo científico publicado en 2015

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

article by Weixing Shen et al published 1 June 2016 in Neuron

Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.

artículo científico publicado en 2010

Meta-analysis of amantadine efficacy for improving preclinical research reliability

artículo científico publicado en 2018

Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism.

artículo científico publicado en 2010

Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders

artículo científico publicado en 2003

Microdialysis in awake macaque monkeys for central nervous system pharmacokinetics

scientific article published on 04 December 2018

Migration and differentiation of human mesenchymal stem cells in the normal rat brain

artículo científico publicado en 2010

Misrepresentation of neuroscience data might give rise to misleading conclusions in the media: the case of attention deficit hyperactivity disorder

artículo científico publicado en 2011

MitoBrain, Putting energy into the brain.

artículo científico publicado en 2016

Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson's disease.

artículo científico publicado en 2017

Modeling Parkinson's disease in primates: The MPTP model

artículo científico publicado en 2012

Models of hyperkinetic disorders in primates

scientific article published on 16 December 2019

Molecular mechanisms of l-DOPA-induced dyskinesia.

artículo científico

Multi-facetted impulsivity following nigral degeneration and dopamine replacement therapy

artículo científico publicado en 2016

Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies.

artículo científico publicado en 2014

NMDA receptor GluN2D subunit participates to levodopa-induced dyskinesia pathophysiology

artículo científico publicado en 2018

Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases

artículo científico publicado en 2016

Nanoscale exploration of the extracellular space in the live brain by combining single carbon nanotube tracking and super-resolution imaging analysis

artículo científico publicado en 2019

Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate

artículo científico publicado en 2010

Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism.

artículo científico publicado en 2008

Neurological drug development: a guide for a start-up biotech

scientific article published on 15 August 2013

Neuroprotection for Parkinson's disease: a call for clinically driven experimental design

scientific article published on 01 July 2003

Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment

scientific article published on 01 January 2004

Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease

artículo científico publicado en 2007

Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials.

artículo científico publicado en 2004

Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced Dyskinesias

artículo científico publicado en 2012

Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats

artículo científico publicado en 2007

Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: a proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGE

artículo científico publicado en 2006

Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset

artículo científico publicado en 2003

Novel pharmacological targets for the treatment of Parkinson's disease

artículo científico publicado en 2006

Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons

artículo científico publicado en 2020

Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate.

artículo científico publicado en 2017

Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

artículo científico publicado en 2020

PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking

artículo científico publicado en 2012

Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey

artículo científico publicado en 2001

Partial bilateral mesencephalic lesions affect D1 but not D2 binding in both the striatum and cortex

artículo científico publicado en 2004

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

artículo científico publicado en 2017

Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.

artículo científico publicado en 2005

Pathophysiology and therapy of L-Dopa-induced dyskinesia

artículo científico publicado en 2003

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

artículo científico

Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.

artículo científico publicado en 2003

Permeability of blood-brain barrier in macaque model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson disease

artículo científico publicado en 2016

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models.

artículo científico publicado en 2018

Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

artículo científico publicado en 2009

Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia.

artículo científico publicado en 2006

Premotor parkinsonism models.

artículo científico publicado en 2014

Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.

artículo científico publicado en 2003

Presymptomatic revelation of experimental parkinsonism.

scholarly article by Erwan Bezard et al published 20 January 1997 in NeuroReport

Priorities in Parkinson's disease research

artículo científico publicado en 2011

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

artículo científico publicado en 2018

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates.

artículo científico publicado en 2015

Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway

artículo científico publicado en 2005

Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson's disease through inhibition of ROS-NO pathway

artículo científico publicado en 2007

Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies

artículo científico publicado en 2015

Protein aggregation in the aging retina.

artículo científico publicado en 2011

Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus

artículo científico publicado en 2015

Quantification of dopamine transporter by 123I-PE2I SPECT and the noninvasive Logan graphical method in Parkinson's disease

artículo científico publicado en 2003

RGS4 is involved in the generation of abnormal involuntary movements in the unilateral 6-OHDA-lesioned rat model of Parkinson's disease.

artículo científico publicado en 2014

RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.

artículo científico publicado en 2007

RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models

artículo científico publicado en 2019

Rabphilin 3A: A novel target for the treatment of levodopa-induced dyskinesias.

artículo científico publicado en 2017

RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease

scientific article published on 01 May 2020

Ratio of inhibited-to-activated pallidal neurons decreases dramatically during passive limb movement in the MPTP-treated monkey

artículo científico publicado en 2000

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

scientific article published on August 2016

Reinforcing properties of Pramipexole in normal and parkinsonian rats

artículo científico publicado en 2012

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

artículo científico publicado en 2001

Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model

artículo científico publicado en 1998

Rise and fall of minocycline in neuroprotection: need to promote publication of negative results

artículo científico publicado en 2004

Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease

artículo científico publicado en 2006

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.

artículo científico publicado en 2014

Shaping of motor responses by incentive values through the basal ganglia.

artículo científico publicado en 2007

Simvastatin decreases levodopa-induced dyskinesia in monkeys, but not in a randomized, placebo-controlled, multiple cross-over ("n-of-1") exploratory trial of simvastatin against levodopa-induced dyskinesia in Parkinson's disease patients.

artículo científico publicado en 2012

Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors.

scientific article published on 14 October 2013

Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model.

artículo científico publicado en 2009

Sonic hedgehog is a neuromodulator in the adult subthalamic nucleus.

artículo científico publicado en 2003

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

artículo científico publicado en 2016

Spontaneous long-term compensatory dopaminergic sprouting in MPTP-treated mice

artículo científico publicado en 2000

Striatal NELF-mediated RNA polymerase II stalling controls L-dopa induced dyskinesia.

artículo científico publicado en 2015

Striatal histone modifications in models of levodopa-induced dyskinesia

artículo científico publicado en 2008

Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease

artículo científico publicado en 2009

Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure.

artículo científico publicado en 2008

Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease.

artículo científico publicado en 2001

Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia.

artículo científico publicado en 2013

Subthalamic stimulation elicits hemiballismus in normal monkey

artículo científico publicado en 1997

Subthalamic stimulation increases striatal tyrosine hydroxylase phosphorylation

artículo científico publicado en 2008

Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate.

artículo científico publicado en 2010

Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells.

artículo científico publicado en 2017

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

artículo científico publicado en 2020

Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats

article

Systemic gene delivery to the central nervous system using Adeno-associated virus

artículo científico publicado en 2014

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques.

artículo científico publicado en 2012

TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

scientific article published on 17 December 2018

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

artículo científico publicado en 2015

Targeting α-synuclein: Therapeutic options

artículo científico publicado en 2016

Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

artículo científico publicado en 2015

Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys.

artículo científico publicado en 2006

The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor lovastatin reduces severity of L-DOPA-induced abnormal involuntary movements in experimental Parkinson's disease

artículo científico publicado en 2008

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.

artículo científico publicado en 2018

The deafferented nonhuman primate is not a reliable model of intractable pain

artículo científico publicado en 2003

The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia

artículo científico publicado en 2018

The hidden side of Parkinson's disease: studying pain, anxiety and depression in animal models

scientific article published on 23 October 2018

The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson's disease patients

scientific article published on 20 June 2019

The mGluR5 negative allosteric modulator dipraglurant reduces dyskinesia in the MPTP macaque model

artículo científico publicado en 2014

The nigrostriatal pathway in Creutzfeldt-Jakob disease.

artículo científico publicado en 2009

The pathologic features of neurocutaneous melanosis in a cynomolgus macaque

artículo científico publicado en 2009

The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research

artículo científico publicado en 2011

The vascular endothelial cell is a new origin of melanin pigment on cynomolgus macaque with neurocutaneous melanosis

artículo científico publicado en 2008

Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease

artículo científico publicado en 2003

Toward a primate model of L-dopa-unresponsive parkinsonism mimicking striatonigral degeneration

artículo científico publicado en 2000

Toward an animal model of restless legs syndrome?

scientific article published on 30 January 2012

Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies

artículo científico publicado en 2019

Treating Parkinson's disease: preserve the spines! (Commentary on Soderstrom et al.).

artículo científico publicado en 2010

U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells

artículo científico publicado en 2017

Unexpected toxicity of very low dose MPTP in mice: A clue to the etiology of Parkinson's disease?

artículo científico publicado en 2015

Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson's disease

artículo científico publicado en 2005

Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys

artículo científico publicado en 2001

Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates

scientific article published on 18 May 2020

Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy

artículo científico publicado en 2017

What should be said to the lay public regarding ADHD etiology

artículo científico publicado en 2011

Why bother using non-human primate models of cognitive disorders in translational research?

artículo científico

Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia

artículo científico publicado en 2014

Wireless neurosensor for full-spectrum electrophysiology recordings during free behavior

artículo científico publicado en 2014

[GRK6, a new therapeutic approach to alleviate L-dopa-induced dyskinesia].

artículo científico publicado en 2010

[L-dopa induced dyskinesia in Parkinson's disease]

artículo científico publicado en 2015

[PSD-95 expression controls L-Dopa dyskinesia].

artículo científico publicado en 2013

[Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure]

scientific article published on 01 April 2008

µ opioid receptor agonism for L-DOPA-induced dyskinesia in Parkinson's disease

artículo científico publicado en 2020

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