Lista de obras - Luigi Bubacco - Dominio Público Uruguay

1H NMR spectroscopy of the binuclear Cu(II) active site of Streptomyces antibioticus tyrosinase

artículo científico publicado en 1999

2-Hydroxypyridine-N-oxide-Embedded Aurones as Potent Human Tyrosinase Inhibitors

artículo científico publicado en 2016

A novel prion protein-tyrosine hydroxylase interaction

artículo científico

A protein-based oxygen biosensor for high-throughput monitoring of cell growth and cell viability.

artículo científico publicado en 2008

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

artículo científico publicado en 2005

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

artículo científico publicado en 2017

Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells

artículo científico publicado en 2010

Alpha-synuclein pore forming activity upon membrane association

article by Laura Tosatto et al published November 2012 in BBA - Biomembranes

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation

artículo científico publicado en 2015

Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

artículo científico publicado en 2016

Are Human Tyrosinase and Related Proteins Suitable Targets for Melanoma Therapy?

artículo científico publicado en 2016

Are dopamine derivatives implicated in the pathogenesis of Parkinson's disease?

artículo científico publicado en 2014

Binding Interactions of Agents That Alter α-Synuclein Aggregation

artículo científico publicado en 2015

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers

artículo científico publicado en 2012

Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity

artículo científico

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

artículo científico publicado en 2008

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside

scientific article published on 20 August 2020

Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro

artículo científico publicado en 2013

Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses

article

Cloning, expression, purification, and spectroscopic analysis of the fragment 57-102 of human alpha-synuclein

artículo científico publicado en 2005

Comparison of the X-ray absorption properties of the binuclear active site of molluscan and arthropodan hemocyanins.

artículo científico publicado en 2001

Comprehensive Structural and Thermodynamic Analysis of Prefibrillar WT α-Synuclein and Its G51D, E46K, and A53T Mutants by a Combination of Small-Angle X-ray Scattering and Variational Bayesian Weighting

artículo científico publicado en 2020

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

artículo científico publicado en 2008

Copper Ions and Parkinson's Disease: Why Is Homeostasis So Relevant?

artículo científico publicado en 2020

Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites

artículo científico publicado en 2013

Covalent α-synuclein dimers: chemico-physical and aggregation properties

artículo científico publicado en 2012

Cross-talk between LRRK2 and PKA: implication for Parkinson's disease?

artículo científico publicado en 2017

Cu(II) coordination in arthropod and mollusk green half-methemocyanins analyzed by electron spin-echo envelope modulation spectroscopy

scientific article published on 01 February 1995

DJ-1 is a copper chaperone acting on SOD1 activation

artículo científico publicado en 2014

DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.

scientific article published on 13 January 2017

Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state

artículo científico

Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells

artículo científico publicado en 2019

Diabetes Mellitus as a Risk Factor for Parkinson's Disease: a Molecular Point of View

scientific article published on 28 March 2018

Differences in the binding of copper(I) to α- and β-synuclein

scientific journal article

Dopamine Oxidation Products as Mitochondrial Endotoxins, a Potential Molecular Mechanism for Preferential Neurodegeneration in Parkinson's Disease

scientific article published on 03 July 2018

Dopamine quinones interact with alpha-synuclein to form unstructured adducts.

artículo científico publicado en 2010

Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53

artículo científico publicado en 2012

Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies.

artículo científico

EPR study of the dinuclear active copper site of tyrosinase from Streptomyces antibioticus

artículo científico publicado en 2000

Effects of Trehalose on Thermodynamic Properties of Alpha-synuclein Revealed through Synchrotron Radiation Circular Dichroism

artículo científico publicado en 2015

Erratum to: Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.

artículo científico publicado en 2016

Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini

artículo científico publicado en 2019

GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.

artículo científico publicado en 2017

GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2

artículo científico publicado en 2013

High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy.

artículo científico publicado en 2017

Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease

artículo científico publicado en 2012

Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?

artículo científico

Human tyrosinase produced in insect cells: a landmark for the screening of new drugs addressing its activity.

artículo científico publicado en 2015

Impacts of increased α-synuclein on clathrin-mediated endocytosis at synapses: implications for neurodegenerative diseases.

artículo científico publicado en 2018

Impaired dopamine metabolism in Parkinson's disease pathogenesis

scientific article published on 20 August 2019

Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction

artículo científico publicado en 2019

Insights into the oligomerization process of the C-terminal domain of human plasma membrane Ca²+-ATPase.

artículo científico publicado en 2010

Insights on Channel-Like Activity of Membrane Bound Alpha-Synuclein

article by Laura Tosatto et al published January 2010 in Biophysical Journal

Interaction and coordination geometries for Ag(I) in the two metal sites of hemocyanin.

artículo científico publicado en 2000

Interaction between alpha-synuclein and metal ions, still looking for a role in the pathogenesis of Parkinson's disease.

artículo científico publicado en 2009

Interaction between the type-3 copper protein tyrosinase and the substrate analogue p-nitrophenol studied by NMR.

artículo científico publicado en 2005

Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols

artículo científico publicado en 2011

Investigation of binding-site homology between mushroom and bacterial tyrosinases by using aurones as effectors

artículo científico publicado en 2014

Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein.

artículo científico publicado en 2007

LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?

artículo científico

LRRK2 deficiency impacts ceramide metabolism in brain.

artículo científico publicado en 2016

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

artículo científico publicado en 2014

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

artículo científico publicado en 2016

Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4

scientific article published on 27 October 2018

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain

artículo científico publicado en 2015

Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells

artículo científico publicado en 2015

Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin

artículo científico

MXAN analysis of the XANES energy region of a mononuclear copper complex: applications to bioinorganic systems

artículo científico publicado en 2005

Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent

artículo científico publicado en 2006

Molecular Evolution and Phylogeny of Sipunculan Hemerythrins

artículo científico publicado en 2005

Molecular Insights and Functional Implication of LRRK2 Dimerization

artículo científico publicado en 2017

Molecular basis of the Bohr effect in arthropod hemocyanin

artículo científico publicado en 2008

Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease

artículo científico publicado en 2010

Molecular heterogeneity of the hemocyanin isolated from the king crab Paralithodes camtschaticae

scientific article published on 01 December 2000

Molecular insights into the interaction between alpha-synuclein and docosahexaenoic acid

artículo científico publicado en 2009

NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

artículo científico publicado en 2015

Neuronal Proteins as Targets of 3-Hydroxykynurenine: Implications in Neurodegenerative Diseases

scientific article published on 26 July 2019

New aspects of the reactivity of tyrosinase

artículo científico publicado en 2004

Nitrite Reductase Activity of Deoxy Carcinus maenas Hemocyanin: Formation of the Half-Met Derivative

scientific article published on 01 February 1996

Number and Brightness analysis of alpha-synuclein oligomerization and the associated mitochondrial morphology alterations in live cells

artículo científico publicado en 2014

Observing the osmophobic effect in action at the single molecule level

artículo científico publicado en 2011

Oxidized derivatives of Octopus vulgaris and Carcinus aestuarii hemocyanins at pH 7.5 and related models by x-ray absorption spectroscopy.

artículo científico publicado en 2002

PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

artículo científico publicado en 2017

Paramagnetic properties of the halide-bound derivatives of oxidised tyrosinase investigated by 1H NMR spectroscopy

artículo científico publicado en 2006

Parkinson's disease and immune system: is the culprit LRRKing in the periphery?

artículo científico publicado en 2012

Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers

artículo científico publicado en 2009

Peptides as modulators of α-synuclein aggregation.

artículo científico publicado en 2015

Preparation and spectroscopic characterization of a coupled binuclear center in cobalt(II)-substituted hemocyanin

artículo científico publicado en 1992

Pressure effects on α-synuclein amyloid fibrils: An experimental investigation on their dissociation and reversible nature.

artículo científico publicado en 2017

Probing kojic acid binding to tyrosinase enzyme: insights from a model complex and QM/MM calculations

scientific article published on 14 November 2013

Quaternary structure and functional properties of Penaeus monodon hemocyanin

scientific article published on 01 April 2005

Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease.

artículo científico publicado en 2017

Role of the tertiary structure in the diphenol oxidase activity of Octopus vulgaris hemocyanin

artículo científico publicado en 2008

Saccharose solid matrix embedded proteins: a new method for sample preparation for X-ray absorption spectroscopy

artículo científico publicado en 2000

Seasonal variation of trehalose and glycerol concentrations in winter snow-active insects

artículo científico publicado en 2008

Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies

artículo científico publicado en 2020

Semisynthetic and Enzyme-Mediated Conjugate Preparations Illuminate the Ubiquitination-Dependent Aggregation of Tau Protein

artículo científico publicado en 2020

Single-molecule force spectroscopy of chimeric polyprotein constructs containing intrinsically disordered domains.

artículo científico publicado en 2012

Single-molecule-level evidence for the osmophobic effect

article

Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties.

artículo científico publicado en 2013

Spectroscopic characterization of the electronic changes in the active site of Streptomyces antibioticus tyrosinase upon binding of transition state analogue inhibitors.

artículo científico publicado en 2002

Stopped-flow fluorescence studies of inhibitor binding to tyrosinase from Streptomyces antibioticus

artículo científico publicado en 2003

Structural and morphological characterization of aggregated species of α-synuclein induced by docosahexaenoic acid

artículo científico publicado en 2011

Structural basis and mechanism of the inhibition of the type-3 copper protein tyrosinase from Streptomyces antibioticus by halide ions

artículo científico publicado en 2002

Structural basis of the lactate-dependent allosteric regulation of oxygen binding in arthropod hemocyanin

artículo científico publicado en 2010

Structural characterization of a high affinity mononuclear site in the copper(II)-α-synuclein complex

artículo científico publicado en 2010

Structural characterization of mononuclear Cu(II) and its nitrite complex in the active site of Carcinus maenas hemocyanin

scientific article published on 01 February 1995

Structural insights on physiological functions and pathological effects of alpha-synuclein.

artículo científico publicado en 2008

Structural properties, conformational stability and oxygen binding properties of Penaeus monodon hemocyanin

artículo científico publicado en 2004

Structural role of the copper ions in the dinuclear active site of Carcinus aestuarii hemocyanin

artículo científico publicado en 2004

Structure and topology of the non-amyloid-beta component fragment of human alpha-synuclein bound to micelles: implications for the aggregation process

artículo científico publicado en 2006

Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.

artículo científico publicado en 2016

Superoxide Dismutases SOD1 and SOD2 Rescue the Toxic Effect of Dopamine-Derived Products in Human SH-SY5Y Neuroblastoma Cells

scientific article published on 21 June 2019

Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson's Disease

scientific article published on 01 August 2018

Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss.

artículo científico publicado en 2018

Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease

artículo científico publicado en 2018

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

artículo científico publicado en 2018

Synthesis, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease.

artículo científico publicado en 2016

The aromatic circular dichroism spectrum as a probe for conformational changes in the active site environment of hemocyanins

artículo científico publicado en 1992

The binding of Cd(II) to the hemocyanin of the Mediterranean crab Carcinus maenas

artículo científico publicado en 1993

The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity

artículo científico publicado en 2014

The functional dissection of the plasma corona of SiO₂-NPs spots histidine rich glycoprotein as a major player able to hamper nanoparticle capture by macrophages

artículo científico publicado en 2015

The oxidation of hemocyanin. Kinetics, reaction mechanism and characterization of met-hemocyanin product

artículo científico publicado en 1995

The reaction of alpha-synuclein with tyrosinase: possible implications for Parkinson disease.

artículo científico publicado en 2008

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

artículo científico publicado en 2019

Trapping tyrosinase key active intermediate under turnover

artículo científico publicado en 2009

Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies

artículo científico publicado en 2013

Tryptophan-to-dye fluorescence energy transfer applied to oxygen sensing by using type-3 copper proteins

artículo científico publicado en 2007

Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease

artículo científico publicado en 2005

Tyrosinase-catalyzed oxidation of fluorophenols

artículo científico publicado en 2002

USP14 inhibition corrects an model of impaired mitophagy

artículo científico publicado en 2018

Understanding the electronic properties of the CuA site from the soluble domain of cytochrome c oxidase through paramagnetic 1H NMR

scientific article published on 01 May 1998

Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau

artículo científico publicado en 2020

Unsymmetrical binding modes of the HOPNO inhibitor of tyrosinase: from model complexes to the enzyme

artículo científico publicado en 2013

Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus

What are the structural features of the active site that define binuclear copper proteins function?

artículo científico publicado en 2004

Worm-like Ising model for protein mechanical unfolding under the effect of osmolytes

artículo científico publicado en 2012

X-ray absorption analysis of the active site of Streptomyces antibioticus Tyrosinase upon binding of transition state analogue inhibitors

artículo científico publicado en 2007

α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling.

artículo científico publicado en 2017

α-Synuclein is a Novel Microtubule Dynamase.

artículo científico publicado en 2016

α-Synuclein oligomers induced by docosahexaenoic acid affect membrane integrity

artículo científico publicado en 2013

Lista de obras de Luigi Bubacco

1H NMR spectroscopy of the binuclear Cu(II) active site of Streptomyces antibioticus tyrosinase

2-Hydroxypyridine-N-oxide-Embedded Aurones as Potent Human Tyrosinase Inhibitors

A novel prion protein-tyrosine hydroxylase interaction

A protein-based oxygen biosensor for high-throughput monitoring of cell growth and cell viability.

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells

Alpha-synuclein pore forming activity upon membrane association

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation

Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

Are Human Tyrosinase and Related Proteins Suitable Targets for Melanoma Therapy?

Are dopamine derivatives implicated in the pathogenesis of Parkinson's disease?

Binding Interactions of Agents That Alter α-Synuclein Aggregation

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers

Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside

Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro

Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses

Cloning, expression, purification, and spectroscopic analysis of the fragment 57-102 of human alpha-synuclein

Comparison of the X-ray absorption properties of the binuclear active site of molluscan and arthropodan hemocyanins.

Comprehensive Structural and Thermodynamic Analysis of Prefibrillar WT α-Synuclein and Its G51D, E46K, and A53T Mutants by a Combination of Small-Angle X-ray Scattering and Variational Bayesian Weighting

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

Copper Ions and Parkinson's Disease: Why Is Homeostasis So Relevant?

Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites

Covalent α-synuclein dimers: chemico-physical and aggregation properties

Cross-talk between LRRK2 and PKA: implication for Parkinson's disease?

Cu(II) coordination in arthropod and mollusk green half-methemocyanins analyzed by electron spin-echo envelope modulation spectroscopy

DJ-1 is a copper chaperone acting on SOD1 activation

DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.

Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state

Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells

Diabetes Mellitus as a Risk Factor for Parkinson's Disease: a Molecular Point of View

Differences in the binding of copper(I) to α- and β-synuclein

Dopamine Oxidation Products as Mitochondrial Endotoxins, a Potential Molecular Mechanism for Preferential Neurodegeneration in Parkinson's Disease

Dopamine quinones interact with alpha-synuclein to form unstructured adducts.

Dopamine-derived quinones affect the structure of the redox sensor DJ-1 through modifications at Cys-106 and Cys-53

Dysfunction of dopamine homeostasis: clues in the hunt for novel Parkinson's disease therapies.

EPR study of the dinuclear active copper site of tyrosinase from Streptomyces antibioticus

Effects of Trehalose on Thermodynamic Properties of Alpha-synuclein Revealed through Synchrotron Radiation Circular Dichroism

Erratum to: Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.

Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini

GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.

GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2

High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy.

Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease

Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?

Human tyrosinase produced in insect cells: a landmark for the screening of new drugs addressing its activity.

Impacts of increased α-synuclein on clathrin-mediated endocytosis at synapses: implications for neurodegenerative diseases.

Impaired dopamine metabolism in Parkinson's disease pathogenesis

Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction

Insights into the oligomerization process of the C-terminal domain of human plasma membrane Ca²+-ATPase.

Insights on Channel-Like Activity of Membrane Bound Alpha-Synuclein

Interaction and coordination geometries for Ag(I) in the two metal sites of hemocyanin.

Interaction between alpha-synuclein and metal ions, still looking for a role in the pathogenesis of Parkinson's disease.

Interaction between the type-3 copper protein tyrosinase and the substrate analogue p-nitrophenol studied by NMR.

Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols

Investigation of binding-site homology between mushroom and bacterial tyrosinases by using aurones as effectors

Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein.

LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?

LRRK2 deficiency impacts ceramide metabolism in brain.

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain

Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells

Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin

MXAN analysis of the XANES energy region of a mononuclear copper complex: applications to bioinorganic systems

Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent

Molecular Evolution and Phylogeny of Sipunculan Hemerythrins

Molecular Insights and Functional Implication of LRRK2 Dimerization

Molecular basis of the Bohr effect in arthropod hemocyanin

Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease

Molecular heterogeneity of the hemocyanin isolated from the king crab Paralithodes camtschaticae

Molecular insights into the interaction between alpha-synuclein and docosahexaenoic acid

NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

Neuronal Proteins as Targets of 3-Hydroxykynurenine: Implications in Neurodegenerative Diseases

New aspects of the reactivity of tyrosinase

Nitrite Reductase Activity of Deoxy Carcinus maenas Hemocyanin: Formation of the Half-Met Derivative