Lista de obras - Gustavo Baldassarre - Dominio Público Uruguay

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

artículo científico publicado en 2013

A truncated form of teratocarcinoma-derived growth factor-1 (cripto-1) mRNA expressed in human colon carcinoma cell lines and tumors.

artículo científico publicado en 2001

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.

artículo científico publicado en 2012

An Integrated Approach Identifies Mediators of Local Recurrence in Head and Neck Squamous Carcinoma.

artículo científico publicado en 2017

Beneficial effects of intraoperative radiotherapy on tumor microenvironment could improve outcomes (Int J Radiat Oncol Biol Phys 2008;72:1575-1581).

artículo científico publicado en 2009

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

artículo científico publicado en 2016

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

artículo científico

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

artículo científico publicado en 2017

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner

artículo científico publicado en 2014

Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland

scientific journal article

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

artículo científico publicado en 2016

Differential effects of protein kinase a sub-units on chinese-hamster-ovary cell cycle and proliferation

article

Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes

artículo científico publicado en 1993

Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer

artículo científico publicado en 2019

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

artículo científico publicado en 2008

Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer

artículo científico publicado en 2018

FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis

artículo científico publicado en 2001

Familial cancer associated with a polymorphism in ARLTS1

artículo científico publicado en 2005

Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.

artículo científico publicado en 2007

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.

artículo científico publicado en 2014

HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel

artículo científico publicado en 2022

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death

artículo científico publicado en 2005

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

artículo científico publicado en 2003

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.

artículo científico publicado en 2006

Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells

artículo científico publicado en 2019

Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line

artículo científico publicado en 1993

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity

artículo científico publicado en 2013

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

artículo científico publicado en 2014

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors

artículo científico publicado en 2018

Linking inflammation to cell cycle progression.

artículo científico publicado en 2004

Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells.

artículo científico publicado en 2017

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

artículo científico publicado en 2009

Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.

artículo científico publicado en 2016

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

artículo científico publicado en 1999

Molecular biology of breast tumors and prognosis

artículo científico publicado en 2016

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

scientific article published on 02 September 2019

Mutant AKT1-E17K is oncogenic in lung epithelial cells

artículo científico publicado en 2015

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

artículo científico publicado en 2003

New light on p27(kip1) in breast cancer

artículo científico publicado en 2012

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

artículo científico publicado en 2001

Pivotal role of the RB family proteins in in vitro thyroid cell transformation

artículo científico publicado en 2000

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: a retrospective study

artículo científico publicado en 2014

Prostaglandin E2 inhibits proliferation and migration of HTR-8/SVneo cells, a human trophoblast-derived cell line.

artículo científico publicado en 2005

RNA splicing alteration in the response to platinum chemotherapy in ovarian cancer: A possible biomarker and therapeutic target

artículo científico publicado en 2020

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.

artículo científico publicado en 2016

Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

artículo científico publicado en 2000

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

artículo científico publicado en 2005

Regulation of BRCA1 transcription by specific single-stranded DNA binding factors

artículo científico publicado en 2003

Regulation of thymosin beta10 expression by TSH and other mitogenic signals in the thyroid gland and in cultured thyrocytes

artículo científico publicado en 1999

Role of T198 modification in the regulation of p27(Kip1) protein stability and function

artículo científico publicado en 2011

STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context

scientific article published on 18 September 2018

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

artículo científico publicado en 2015

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

artículo científico publicado en 2020

Somatostatin as a regulator of first-trimester human trophoblast functions

artículo científico publicado en 2008

Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity

artículo científico publicado en 2020

Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis

artículo científico publicado en 2018

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

artículo científico publicado en 2008

Stathmin is dispensable for tumor onset in mice

artículo científico publicado en 2012

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

artículo científico publicado en 2013

Stathmin: a protein with many tasks. New biomarker and potential target in cancer

artículo científico

TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells

artículo científico publicado en 2019

Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding

artículo científico publicado en 2008

The T197A Knock-in Model of Gene to Study the Effects of p27 Restoration

article

The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.

artículo científico publicado en 2009

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

scientific article published on 10 December 2018

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

artículo científico publicado en 2005

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

scientific article published on 08 May 2019

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

scientific journal article

p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.

artículo científico publicado en 2005

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

artículo científico publicado en 2008

p27kip1 at the crossroad between actin and microtubule dynamics

scientific article published on 01 April 2019

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.

artículo científico publicado en 2015

p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling

artículo científico publicado en 2010

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms.

artículo científico publicado en 2016

p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.

artículo científico publicado en 2014

Lista de obras de Gustavo Baldassarre

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

A truncated form of teratocarcinoma-derived growth factor-1 (cripto-1) mRNA expressed in human colon carcinoma cell lines and tumors.

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.

An Integrated Approach Identifies Mediators of Local Recurrence in Head and Neck Squamous Carcinoma.

Beneficial effects of intraoperative radiotherapy on tumor microenvironment could improve outcomes (Int J Radiat Oncol Biol Phys 2008;72:1575-1581).

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC.

CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner

Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study.

Differential effects of protein kinase a sub-units on chinese-hamster-ovary cell cycle and proliferation

Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes

Downregulation of miR-223 Expression Is an Early Event during Mammary Transformation and Confers Resistance to CDK4/6 Inhibitors in Luminal Breast Cancer

E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer

FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis

Familial cancer associated with a polymorphism in ARLTS1

Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.

HMGA1 positively regulates the microtubule-destabilizing protein stathmin promoting motility in TNBC cells and decreasing tumour sensitivity to paclitaxel

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.

Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells

Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors

Linking inflammation to cell cycle progression.

Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells.

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

Molecular biology of breast tumors and prognosis

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model

Mutant AKT1-E17K is oncogenic in lung epithelial cells

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

New light on p27(kip1) in breast cancer

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

Pivotal role of the RB family proteins in in vitro thyroid cell transformation

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: a retrospective study

Prostaglandin E2 inhibits proliferation and migration of HTR-8/SVneo cells, a human trophoblast-derived cell line.

RNA splicing alteration in the response to platinum chemotherapy in ovarian cancer: A possible biomarker and therapeutic target

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.

Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

Regulation of BRCA1 transcription by specific single-stranded DNA binding factors

Regulation of thymosin beta10 expression by TSH and other mitogenic signals in the thyroid gland and in cultured thyrocytes

Role of T198 modification in the regulation of p27(Kip1) protein stability and function

STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

Somatostatin as a regulator of first-trimester human trophoblast functions

Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity

Stathmin Is Required for Normal Mouse Mammary Gland Development and Δ16HER2-Driven Tumorigenesis

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

Stathmin is dispensable for tumor onset in mice

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.

Stathmin: a protein with many tasks. New biomarker and potential target in cancer

TIMP-1 is Overexpressed and Secreted by Platinum Resistant Epithelial Ovarian Cancer Cells

Targeted intraoperative radiotherapy impairs the stimulation of breast cancer cell proliferation and invasion caused by surgical wounding

The T197A Knock-in Model of Gene to Study the Effects of p27 Restoration

The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

p27kip1 at the crossroad between actin and microtubule dynamics

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.

p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms.

p70S6 kinase mediates breast cancer cell survival in response to surgical wound fluid stimulation.