Lista de obras - Victor A. Maltsev - Dominio Público Uruguay

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

artículo científico publicado en 2010

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells.

artículo científico publicado en 2018

A negative resistance region underlies the triggering property of membrane potential in human T-lymphocytes

artículo científico publicado el 1 de noviembre de 1992

A novel quantitative explanation for the autonomic modulation of cardiac pacemaker cell automaticity via a dynamic system of sarcolemmal and intracellular proteins.

artículo científico publicado en 2010

Beat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node Cells

artículo científico publicado en 2013

Beat-to-beat Ca(2+)-dependent regulation of sinoatrial nodal pacemaker cell rate and rhythm.

artículo científico publicado en 2011

Biophysical characterization of the underappreciated and important relationship between heart rate variability and heart rate

artículo científico publicado en 2014

Calcium cycling protein density and functional importance to automaticity of isolated sinoatrial nodal cells are independent of cell size

artículo científico publicado en 2007

Calcium signalling in individual T-cells measured by confocal microscopy.

artículo científico publicado en 1994

Calpain inhibition reduces amplitude and accelerates decay of the late sodium current in ventricular myocytes from dogs with chronic heart failure

artículo científico publicado en 2013

Cardiac pacemaker cell failure with preserved I(f), I(CaL), and I(Kr): a lesson about pacemaker function learned from ischemia-induced bradycardia

artículo científico publicado en 2006

Cardiomyocyte-like cells differentiated in vitro from embryonic carcinoma cells P19 are characterized by functional expression of adrenoceptors and Ca2+ channels

scientific article published on 01 July 1994

Cardiomyocytes derived from embryonic stem cells.

artículo científico publicado en 2005

Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents

artículo científico publicado en 1994

Cholinergic receptor signaling modulates spontaneous firing of sinoatrial nodal cells via integrated effects on PKA-dependent Ca(2+) cycling and I(KACh).

scientific article published on 19 June 2009

Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

artículo científico publicado en 2006

Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts

artículo científico publicado en 2014

Crosstalk between mitochondrial and sarcoplasmic reticulum Ca2+ cycling modulates cardiac pacemaker cell automaticity

artículo científico publicado en 2012

Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance

artículo científico publicado en 2003

Cytochalasin D alters kinetics of Ca2+ transient in rat ventricular cardiomyocytes: an effect of altered actin cytoskeleton?

artículo científico publicado en 1998

Cytoskeleton modulates coupling between availability and activation of cardiac sodium channel

artículo científico publicado en 1997

Development of cardiomyocytes expressing cardiac-specific genes, action potentials, and ionic channels during embryonic stem cell-derived cardiogenesis

artículo científico publicado en 1995

Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process.

artículo científico publicado en 2004

Differential role of the alpha1C subunit tails in regulation of the Cav1.2 channel by membrane potential, beta subunits, and Ca2+ ions

artículo científico publicado en 2005

Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin

scientific journal article

Down-regulation of sodium current in chronic heart failure: effect of long-term therapy with carvedilol

artículo científico publicado en 2002

Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types

artículo científico publicado en 1993

Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis

artículo científico publicado en 1997

Establishment of beta-adrenergic modulation of L-type Ca2+ current in the early stages of cardiomyocyte development

artículo científico publicado en 1999

Gating of the late Na+ channel in normal and failing human myocardium

artículo científico publicado en 2002

High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells

artículo científico publicado en 2006

In vitro cellular models for cardiac development and pharmacotoxicology

artículo científico publicado en 1995

In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid

scientific article published on 01 October 1994

In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid

scientific article published on 01 January 1994

Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.

artículo científico publicado en 2009

Late sodium current in failing heart: friend or foe?

artículo científico publicado en 2007

Late sodium current is a novel target for amiodarone: studies in failing human myocardium

artículo científico publicado en 2001

Letter to the editor: "Validating the requirement for beat-to-beat coupling of the Ca2+ clock and M clock in pacemaker cell normal automaticity".

artículo científico publicado en 2011

Life and death of a cardiac calcium spark

artículo científico publicado en 2013

Mechanisms of beat-to-beat regulation of cardiac pacemaker cell function by Ca²⁺ cycling dynamics.

artículo científico publicado en 2013

Membrane potential fluctuations resulting from submembrane Ca2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state

artículo científico publicado en 2006

Minding the gaps that link intrinsic circadian clock within the heart to its intrinsic ultradian pacemaker clocks. Focus on "The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility".

artículo científico publicado en 2013

Modern concepts concerning the origin of the heartbeat.

artículo científico publicado en 2013

Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: developmentally regulated expression of myogenic determination genes and functional expression of ionic currents

artículo científico publicado en 1994

Na+ channel function, regulation, structure, trafficking and sequestration

artículo científico publicado en 2015

New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: bradycardic effects of ivabradine are linked to suppression of intracellular Ca²⁺ cycling.

artículo científico publicado en 2013

Normal heart rhythm is initiated and regulated by an intracellular calcium clock within pacemaker cells

artículo científico publicado en 2007

Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes

artículo científico publicado en 1998

Numerical Modeling Calcium and CaMKII Effects in the SA Node

artículo científico publicado en 2014

Numerical models based on a minimal set of sarcolemmal electrogenic proteins and an intracellular Ca(2+) clock generate robust, flexible, and energy-efficient cardiac pacemaking

artículo científico publicado en 2013

Oscillating and triggering properties of T cell membrane potential

artículo científico publicado en 1990

Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.

artículo científico publicado en 2004

Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure.

artículo científico publicado en 2004

Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure ⬇️

artículo científico publicado el 24 de junio de 2011

Rebuttal: What If the shoe doesn't fit? “The funny current has a major pacemaking role in the sinus node” ⬇️

artículo científico publicado el 16 de septiembre de 2011

Relationship between action potential, contraction-relaxation pattern, and intracellular Ca2+ transient in cardiomyocytes of dogs with chronic heart failure

artículo científico publicado en 1998

Relationship between steady-state activation and availability of cardiac sodium channel: evidence of uncoupling

scientific article published on 01 February 1998

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

artículo científico publicado en 1999

Reprogramming paces the heart

artículo científico publicado en 2013

Rhythmic Ca2+ oscillations drive sinoatrial nodal cell pacemaker function to make the heart tick.

artículo científico publicado en 2005

Rhythmic ryanodine receptor Ca2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization

artículo científico publicado en 2004

Spontaneous, local diastolic subsarcolemmal calcium releases in single, isolated guinea-pig sinoatrial nodal cells

artículo científico publicado en 2017

Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels

artículo científico publicado en 2017

Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model.

artículo científico publicado en 2009

The funny current in the context of the coupled-clock pacemaker cell system ⬇️

artículo científico publicado el 16 de septiembre de 2011

The integration of spontaneous intracellular Ca2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker.

artículo científico publicado en 2006

The missing link in the mystery of normal automaticity of cardiac pacemaker cells.

artículo científico publicado en 2008

Lista de obras de Victor A. Maltsev

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells.

A negative resistance region underlies the triggering property of membrane potential in human T-lymphocytes

A novel quantitative explanation for the autonomic modulation of cardiac pacemaker cell automaticity via a dynamic system of sarcolemmal and intracellular proteins.

Beat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node Cells

Beat-to-beat Ca(2+)-dependent regulation of sinoatrial nodal pacemaker cell rate and rhythm.

Biophysical characterization of the underappreciated and important relationship between heart rate variability and heart rate

Calcium cycling protein density and functional importance to automaticity of isolated sinoatrial nodal cells are independent of cell size

Calcium signalling in individual T-cells measured by confocal microscopy.

Calpain inhibition reduces amplitude and accelerates decay of the late sodium current in ventricular myocytes from dogs with chronic heart failure

Cardiac pacemaker cell failure with preserved I(f), I(CaL), and I(Kr): a lesson about pacemaker function learned from ischemia-induced bradycardia

Cardiomyocyte-like cells differentiated in vitro from embryonic carcinoma cells P19 are characterized by functional expression of adrenoceptors and Ca2+ channels

Cardiomyocytes derived from embryonic stem cells.

Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents

Cholinergic receptor signaling modulates spontaneous firing of sinoatrial nodal cells via integrated effects on PKA-dependent Ca(2+) cycling and I(KACh).

Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

Contribution of sodium channel neuronal isoform Nav1.1 to late sodium current in ventricular myocytes from failing hearts

Crosstalk between mitochondrial and sarcoplasmic reticulum Ca2+ cycling modulates cardiac pacemaker cell automaticity

Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance

Cytochalasin D alters kinetics of Ca2+ transient in rat ventricular cardiomyocytes: an effect of altered actin cytoskeleton?

Cytoskeleton modulates coupling between availability and activation of cardiac sodium channel

Development of cardiomyocytes expressing cardiac-specific genes, action potentials, and ionic channels during embryonic stem cell-derived cardiogenesis

Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process.

Differential role of the alpha1C subunit tails in regulation of the Cav1.2 channel by membrane potential, beta subunits, and Ca2+ ions

Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin

Down-regulation of sodium current in chronic heart failure: effect of long-term therapy with carvedilol

Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types

Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis

Establishment of beta-adrenergic modulation of L-type Ca2+ current in the early stages of cardiomyocyte development

Gating of the late Na+ channel in normal and failing human myocardium

High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells

In vitro cellular models for cardiac development and pharmacotoxicology

In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid

In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid

Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.

Late sodium current in failing heart: friend or foe?

Late sodium current is a novel target for amiodarone: studies in failing human myocardium

Letter to the editor: "Validating the requirement for beat-to-beat coupling of the Ca2+ clock and M clock in pacemaker cell normal automaticity".

Life and death of a cardiac calcium spark

Mechanisms of beat-to-beat regulation of cardiac pacemaker cell function by Ca²⁺ cycling dynamics.

Membrane potential fluctuations resulting from submembrane Ca2+ releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that controls their chronotropic state

Minding the gaps that link intrinsic circadian clock within the heart to its intrinsic ultradian pacemaker clocks. Focus on "The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility".

Modern concepts concerning the origin of the heartbeat.

Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: developmentally regulated expression of myogenic determination genes and functional expression of ionic currents

Na+ channel function, regulation, structure, trafficking and sequestration

New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: bradycardic effects of ivabradine are linked to suppression of intracellular Ca²⁺ cycling.

Normal heart rhythm is initiated and regulated by an intracellular calcium clock within pacemaker cells

Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes

Numerical Modeling Calcium and CaMKII Effects in the SA Node

Numerical models based on a minimal set of sarcolemmal electrogenic proteins and an intracellular Ca(2+) clock generate robust, flexible, and energy-efficient cardiac pacemaking

Oscillating and triggering properties of T cell membrane potential

Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.

Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure.

Post-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure ⬇️

Rebuttal: What If the shoe doesn't fit? “The funny current has a major pacemaking role in the sinus node” ⬇️

Relationship between action potential, contraction-relaxation pattern, and intracellular Ca2+ transient in cardiomyocytes of dogs with chronic heart failure

Relationship between steady-state activation and availability of cardiac sodium channel: evidence of uncoupling

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

Reprogramming paces the heart

Rhythmic Ca2+ oscillations drive sinoatrial nodal cell pacemaker function to make the heart tick.

Rhythmic ryanodine receptor Ca2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization

Spontaneous, local diastolic subsarcolemmal calcium releases in single, isolated guinea-pig sinoatrial nodal cells

Stabilization of diastolic calcium signal via calcium pump regulation of complex local calcium releases and transient decay in a computational model of cardiac pacemaker cell with individual release channels

Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model.

The funny current in the context of the coupled-clock pacemaker cell system ⬇️

The integration of spontaneous intracellular Ca2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker.

The missing link in the mystery of normal automaticity of cardiac pacemaker cells.