Lista de obras - Luis F. Santana - Dominio Público Uruguay

A G-coupled purinergic receptor boosts Ca influx and vascular contractility during diabetic hyperglycemia

artículo científico publicado en 2019

A New Mutation in FIG4 Causes a Severe Form of CMT4J Involving TRPV4 in the Pathogenic Cascade

artículo científico publicado en 2017

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

artículo científico publicado en 2015

A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics.

artículo científico publicado en 2018

A stochastic model of ion channel cluster formation in the plasma membrane

artículo científico publicado en 2019

A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons

scientific article published on 30 September 2019

A-kinase anchoring proteins: getting to the heart of the matter.

scientific article published on March 2010

AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.

artículo científico publicado en 2013

AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension

artículo científico publicado en 2008

AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.

artículo científico publicado en 2015

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

artículo científico publicado en 2014

Activation of NFATc3 Down-regulates the β1 Subunit of Large Conductance, Calcium-activated K+Channels in Arterial Smooth Muscle and Contributes to Hypertension

artículo científico publicado en 2006

Adding accessories for hypertension: α2δ-1 subunits upregulate CaV1.2 channels in arterial myocytes in a model of genetic hypertension

artículo científico publicado en 2012

Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca 2+ Release

artículo científico publicado en 2005

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria

scientific journal article

Anchored phosphatases modulate glucose homeostasis

scientific journal article

BIN1 Induces the Formation of T-Tubules and Adult-Like Ca2+ Release Units in Developing Cardiomyocytes.

artículo científico publicado en 2018

Ca 2+ signaling amplification by oligomerization of L-type Ca v 1.2 channels ⬇️

artículo científico publicado el 17 de enero de 2012

Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels

artículo científico publicado en 2016

Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance

artículo científico publicado en 1998

Calcium Channels in Vascular Smooth Muscle.

artículo científico publicado en 2016

Calcium sparklets in arterial smooth muscle ⬇️

scientific article published on 21 January 2008

Calcium sparklets regulate local and global calcium in murine arterial smooth muscle

artículo científico publicado en 2006

Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes.

artículo científico publicado en 1997

Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice

artículo científico publicado en 2012

Cav1.3 channels produce persistent calcium sparklets, but Cav1.2 channels are responsible for sparklets in mouse arterial smooth muscle

artículo científico publicado en 2007

Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8).

artículo científico publicado en 2013

Constitutively active L-type Ca2+ channels

artículo científico publicado en 2005

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

artículo científico publicado en 1997

Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart

artículo científico publicado en 2006

Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity

scientific article published on 10 October 2019

Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes.

artículo científico publicado en 2017

Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle

artículo científico publicado en 2013

Downregulation of the BK Channel β1 Subunit in Genetic Hypertension ⬇️

artículo científico publicado el 9 de octubre de 2003

Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating

artículo científico publicado en 2018

Dynamic changes in sarcoplasmic reticulum structure in ventricular myocytes

artículo científico publicado en 2011

Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery.

artículo científico publicado en 2013

Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells

artículo científico publicado en 2009

Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes.

artículo científico publicado en 2002

Graded Ca2+/calmodulin-dependent coupling of voltage-gated CaV1.2 channels

artículo científico publicado en 2015

How does the shape of the cardiac action potential control calcium signaling and contraction in the heart?

artículo científico publicado en 2010

Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes.

artículo científico publicado en 2017

Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome

artículo científico publicado en 2010

Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes

scientific article published on 22 January 2020

Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure

artículo científico publicado en 2010

Kv2 channels oppose myogenic constriction of rat cerebral arteries.

artículo científico publicado en 2006

Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle

artículo científico publicado en 2020

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons

scientific article published on 30 October 2019

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

artículo científico publicado en 2014

Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes

artículo científico publicado en 2009

Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.

artículo científico publicado en 2016

Maladaptive response of arterial myocytes to chronic exposure to Ca2+ channel blockers

artículo científico publicado en 2020

Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle

artículo científico publicado en 2006

Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall

artículo científico publicado en 2006

Metabolic-electrical control of coronary blood flow

scientific article published on 01 April 2020

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

artículo científico publicado en 2014

Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

artículo científico publicado en 2011

Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy

artículo científico publicado en 2011

Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling

artículo científico publicado en 2009

NFAT-dependent excitation-transcription coupling in heart

artículo científico publicado en 2008

NFATc3 regulates Kv2.1 expression in arterial smooth muscle

artículo científico publicado en 2004

NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic beta adrenergic stimulation

artículo científico publicado en 2008

NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction

artículo científico publicado en 2004

Natural inequalities: why some L-type Ca2+ channels work harder than others

artículo científico publicado en 2010

On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle.

artículo científico publicado en 2006

Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging.

artículo científico publicado en 2009

Oxidative stress decreases microtubule growth and stability in ventricular myocytes

artículo científico publicado en 2016

Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes

artículo científico publicado en 2010

Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.

artículo científico publicado en 2006

Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes

artículo científico publicado en 2001

Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage.

artículo científico publicado en 2017

Regulation of L-type calcium channel sparklet activity by c-Src and PKC-α.

artículo científico publicado en 2013

Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle

artículo científico publicado en 2011

Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein

artículo científico publicado en 2011

Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure.

artículo científico publicado en 2001

SMAKing Ca2+ sparks in arterial myocytes

artículo científico publicado en 2007

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

artículo científico publicado en 2018

Sodium current and arrhythmogenesis in heart failure.

artículo científico publicado en 2005

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels

artículo científico publicado en 2010

The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension

artículo científico publicado en 2008

The long and winding road home: how junctin and triadin find their way to the junctional SR.

artículo científico publicado en 2015

Two mechanisms of quantized calcium release in skeletal muscle

artículo científico publicado en 1996

Lista de obras de Luis F. Santana

A G-coupled purinergic receptor boosts Ca influx and vascular contractility during diabetic hyperglycemia

A New Mutation in FIG4 Causes a Severe Form of CMT4J Involving TRPV4 in the Pathogenic Cascade

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells

A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics.

A stochastic model of ion channel cluster formation in the plasma membrane

A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons

A-kinase anchoring proteins: getting to the heart of the matter.

AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.

AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension

AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension

Activation of NFATc3 Down-regulates the β1 Subunit of Large Conductance, Calcium-activated K+Channels in Arterial Smooth Muscle and Contributes to Hypertension

Adding accessories for hypertension: α2δ-1 subunits upregulate CaV1.2 channels in arterial myocytes in a model of genetic hypertension

Alterations in Early Action Potential Repolarization Causes Localized Failure of Sarcoplasmic Reticulum Ca 2+ Release

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria

Anchored phosphatases modulate glucose homeostasis

BIN1 Induces the Formation of T-Tubules and Adult-Like Ca2+ Release Units in Developing Cardiomyocytes.

Ca 2+ signaling amplification by oligomerization of L-type Ca v 1.2 channels ⬇️

Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels

Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance

Calcium Channels in Vascular Smooth Muscle.

Calcium sparklets in arterial smooth muscle ⬇️

Calcium sparklets regulate local and global calcium in murine arterial smooth muscle

Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes.

Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice

Cav1.3 channels produce persistent calcium sparklets, but Cav1.2 channels are responsible for sparklets in mouse arterial smooth muscle

Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8).

Constitutively active L-type Ca2+ channels

Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure

Differential calcineurin/NFATc3 activity contributes to the Ito transmural gradient in the mouse heart

Disease-associated mutations in Niemann-Pick type C1 alter ER calcium signaling and neuronal plasticity

Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes.

Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle

Downregulation of the BK Channel β1 Subunit in Genetic Hypertension ⬇️

Dynamic L-type CaV1.2 channel trafficking facilitates CaV1.2 clustering and cooperative gating

Dynamic changes in sarcoplasmic reticulum structure in ventricular myocytes

Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery.

Elevated Ca2+ sparklet activity during acute hyperglycemia and diabetes in cerebral arterial smooth muscle cells

Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes.

Graded Ca2+/calmodulin-dependent coupling of voltage-gated CaV1.2 channels

How does the shape of the cardiac action potential control calcium signaling and contraction in the heart?

Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes.

Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome

Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes

Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure

Kv2 channels oppose myogenic constriction of rat cerebral arteries.

Kv2.1 channels play opposing roles in regulating membrane potential, Ca2+ channel function, and myogenic tone in arterial smooth muscle

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle

Local control of excitation-contraction coupling in human embryonic stem cell-derived cardiomyocytes

Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.

Maladaptive response of arterial myocytes to chronic exposure to Ca2+ channel blockers

Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle

Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall

Metabolic-electrical control of coronary blood flow

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy

Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling

NFAT-dependent excitation-transcription coupling in heart

NFATc3 regulates Kv2.1 expression in arterial smooth muscle

NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic beta adrenergic stimulation

NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction

Natural inequalities: why some L-type Ca2+ channels work harder than others

On the loose: uncaging Ca2+ -induced Ca2+ release in smooth muscle.

Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging.

Oxidative stress decreases microtubule growth and stability in ventricular myocytes

Phosphodiesterase 8A (PDE8A) regulates excitation-contraction coupling in ventricular myocytes

Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.

Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes

Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage.

Regulation of L-type calcium channel sparklet activity by c-Src and PKC-α.

Relationship between Ca2+ sparklets and sarcoplasmic reticulum Ca2+ load and release in rat cerebral arterial smooth muscle

Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein

Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure.

SMAKing Ca2+ sparks in arterial myocytes

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

Sodium current and arrhythmogenesis in heart failure.

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels