Lista de obras - Jose A. Villadangos - Dominio Público Uruguay

A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.

artículo científico publicado en 2011

A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells.

scientific article published on 16 August 2011

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

artículo científico publicado en 2014

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

artículo científico publicado en 2020

Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

scientific article published on 18 May 2020

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

article

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes.

artículo científico publicado en 2016

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

artículo científico publicado en 2015

Antigen presentation by dendritic cells in vivo

artículo científico publicado en 2009

Antigen processing

artículo científico publicado en 2013

Antigen processing and recognition

artículo científico publicado en 2006

Antigen-presenting cells look within during influenza infection

artículo científico publicado en 2015

Antigen-specific impairment of adoptive T-cell therapy against cancer: players, mechanisms, solutions and a hypothesis

artículo científico publicado en 2016

Author Correction: Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

artículo científico publicado en 2020

Autophagy and Mechanisms of Effective Immunity ⬇️

artículo científico publicado el 4 de abril de 2012

Blood-stage Plasmodium berghei infection leads to short-lived parasite-associated antigen presentation by dendritic cells

artículo científico publicado en 2010

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells

artículo científico publicado en 2008

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

artículo científico publicado en 2020

CD69 does not affect the extent of T cell priming

artículo científico publicado en 2012

Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus ⬇️

artículo científico publicado el 17 de abril de 1998

Cathepsin S activity regulates antigen presentation and immunity ⬇️

artículo científico publicado el 1 de junio de 1998

Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

artículo científico publicado en 1999

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation ⬇️

artículo científico publicado el 14 de abril de 1998

Changes in the repertoire of peptides bound to HLA-B27 subtypes and to site-specific mutants inside and outside pocket B.

artículo científico publicado en 1993

Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses

artículo científico publicado en 2009

Cognate CD4(+) T cell licensing of dendritic cells in CD8(+) T cell immunity

artículo científico publicado en 2004

Consequences of direct and indirect activation of dendritic cells on antigen presentation: Functional implications and clinical considerations ⬇️

artículo científico publicado el 27 de noviembre de 2012

Control of MHC II antigen presentation by ubiquitination.

artículo científico publicado en 2012

Control of MHC class II antigen presentation in dendritic cells: a balance between creative and destructive forces.

artículo científico publicado en 2005

Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination.

artículo científico publicado en 2015

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

artículo científico publicado en 2004

Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1 ⬇️

artículo científico publicado el 1 de mayo de 2003

Cutting edge: B220+CCR9- dendritic cells are not plasmacytoid dendritic cells but are precursors of conventional dendritic cells.

artículo científico publicado en 2009

Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells

artículo científico publicado en 2006

DEC-205 is a cell surface receptor for CpG oligonucleotides

artículo científico publicado en 2012

DNA-based probes for flow cytometry analysis of endocytosis and recycling

artículo científico publicado en 2016

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism ⬇️

artículo científico publicado el 18 de agosto de 1997

Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37.

artículo científico publicado en 2016

Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens

artículo científico publicado en 2007

Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis

artículo científico publicado en 2003

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

artículo científico publicado en 2005

Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.

scientific article published on 25 February 2014

Different cross-presentation pathways in steady-state and inflammatory dendritic cells

scientific journal article

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

article

Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation.

artículo científico publicado en 2012

Differential expression of pathogen-recognition molecules between dendritic cell subsets revealed by plasma membrane proteomic analysis

artículo científico publicado en 2010

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

artículo científico publicado en 2015

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells

article

Downregulation of MHC Class I Expression by Influenza A and B Viruses

artículo científico publicado en 2019

Editorial overview: New proteins, cellular processes and intercellular interactions involved in antigen presentation

scientific article published on 01 June 2019

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

artículo científico publicado en 2015

Endolysosomal proteases and their inhibitors in immunity.

scientific article published on December 2009

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

scientific article published on 21 September 2020

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

artículo científico publicado en 1996

Factors determining the spontaneous activation of splenic dendritic cells in culture

article

Found in translation: the human equivalent of mouse CD8+ dendritic cells

artículo científico publicado en 2010

GM-CSF increases cross-presentation and CD103 expression by mouse CD8⁺ spleen dendritic cells

artículo científico publicado en 2011

HLA‐B27 (B*2701) specificity for peptides lacking Arg2 is determined by polymorphism outside the B pocket ⬇️

artículo científico publicado el 1 de junio de 1997

Hepatitis B virus-like particles access major histocompatibility class I and II antigen presentation pathways in primary dendritic cells

artículo científico publicado en 2013

Hold on, the monocytes are coming!

artículo científico publicado en 2007

How MR1 Presents a Pathogen Metabolic Signature to Mucosal-Associated Invariant T (MAIT) Cells.

artículo científico publicado en 2017

Hydrocortisone prevents immunosuppression by interleukin-10+ natural killer cells after trauma-hemorrhage

artículo científico publicado en 2014

IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.

artículo científico publicado en 2011

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

scientific article published on 13 March 2012

Induction of antigen-specific effector-phase tolerance following vaccination against a previously ignored B-cell lymphoma

artículo científico publicado en 2010

Inflammation conditions mature dendritic cells to retain the capacity to present new antigens but with altered cytokine secretion function.

artículo científico publicado en 2014

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

artículo científico publicado en 2007

Introducing this special issue

artículo científico publicado en 2015

Invariant chain controls the activity of extracellular cathepsin L.

artículo científico publicado en 2002

Is it a DC, is it an NK? No, it's an IKDC

article

Life cycle, migration and antigen presenting functions of spleen and lymph node dendritic cells: limitations of the Langerhans cells paradigm

artículo científico publicado en 2005

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

artículo científico publicado en 2017

MARCH ligases in immunity

scientific article published on 04 May 2019

MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway

scientific article published on 12 July 2018

MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation

artículo científico publicado en 2001

MR1 antigen presentation to MAIT cells: new ligands, diverse pathways?

artículo científico publicado en 2018

MR1 presentation of vitamin B-based metabolite ligands.

artículo científico publicado en 2015

Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα)

scientific article published on 01 October 2019

Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

article

Modulation of antigen presentation by intracellular trafficking.

artículo científico

Modulation of dendritic cell antigen presentation by pathogens, tissue damage and secondary inflammatory signals.

artículo científico publicado en 2014

Modulation of peptide binding by HLA-B27 polymorphism in pockets A and B, and peptide specificity of B*2703.

artículo científico publicado en 1995

Most lymphoid organ dendritic cell types are phenotypically and functionally immature

artículo científico publicado en 2003

No driving without a license

article

Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling

article

Organ-specific isoform selection of fatty acid-binding proteins in tissue-resident lymphocytes

scientific article published on 01 April 2020

Outside looking in: the inner workings of the cross-presentation pathway within dendritic cells

artículo científico publicado en 2007

Pathophysiological role of respiratory dysbiosis in hospital-acquired pneumonia

artículo científico publicado en 2019

Presentation of antigens by MHC class II molecules: getting the most out of them

scientific journal article

Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells

artículo científico publicado en 2007

Rapid deletion and inactivation of CTLs upon recognition of a number of target cells over a critical threshold.

artículo científico publicado en 2013

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

artículo científico publicado en 2001

Regulation of antigen presentation and cross-presentation in the dendritic cell network: facts, hypothesis, and immunological implications.

artículo científico publicado en 2005

Reply to: "Differential expression of serpins may selectively license distinct granzyme B functions including antigen cross-presentation".

artículo científico publicado en 2017

Resident and monocyte-derived dendritic cells become dominant IL-12 producers under different conditions and signaling pathways

artículo científico publicado en 2010

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming

artículo científico publicado en 2015

Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage

artículo científico publicado en 2003

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

artículo científico publicado en 2008

Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.

artículo científico publicado en 2012

Serpinb9 is a marker of antigen cross-presenting dendritic cells.

artículo científico publicado en 2016

Shutdown of immunological priming and presentation after in vivo administration of adenovirus

artículo científico publicado en 2011

Structure of HLA-B27-specific T cell epitopes. Antigen presentation in B2703 is limited mostly to a subset of the antigenic determinants on B2705

scientific article published on 01 October 1994

Switching from a restricted to an effective CD4 T cell response by activating CD8+ murine dendritic cells with a Toll-like receptor 9 ligand

article

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity

artículo científico publicado en 2006

Target Density, Not Affinity or Avidity of Antigen Recognition, Determines Adoptive T Cell Therapy Outcomes in a Mouse Lymphoma Model.

artículo científico publicado en 2016

Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

artículo científico publicado en 2013

The Acquisition of Antigen Cross-Presentation Function by Newly Formed Dendritic Cells

artículo científico publicado en 2011

The MARCH family joins the antigen cross-presentation party.

artículo científico publicado en 2017

The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture

artículo científico publicado en 2006

The inflammatory cytokine, GM-CSF, alters the developmental outcome of murine dendritic cells

artículo científico publicado en 2012

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

artículo científico publicado en 2016

The role of dendritic cell alterations in susceptibility to hospital-acquired infections during critical-illness related immunosuppression

artículo científico

Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery

artículo científico publicado en 2004

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection

artículo científico publicado en 2016

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86

artículo científico publicado en 2022

Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4+ T Cells

artículo científico publicado en 2020

Understanding host–pathogen interaction

artículo científico publicado en 2016

Lista de obras de Jose A. Villadangos

A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.

A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells.

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes.

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

Antigen presentation by dendritic cells in vivo

Antigen processing

Antigen processing and recognition

Antigen-presenting cells look within during influenza infection

Antigen-specific impairment of adoptive T-cell therapy against cancer: players, mechanisms, solutions and a hypothesis

Author Correction: Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

Autophagy and Mechanisms of Effective Immunity ⬇️

Blood-stage Plasmodium berghei infection leads to short-lived parasite-associated antigen presentation by dendritic cells

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells

Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells

CD69 does not affect the extent of T cell priming

Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus ⬇️

Cathepsin S activity regulates antigen presentation and immunity ⬇️

Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation ⬇️

Changes in the repertoire of peptides bound to HLA-B27 subtypes and to site-specific mutants inside and outside pocket B.

Characterization of an immediate splenic precursor of CD8+ dendritic cells capable of inducing antiviral T cell responses

Cognate CD4(+) T cell licensing of dendritic cells in CD8(+) T cell immunity

Consequences of direct and indirect activation of dendritic cells on antigen presentation: Functional implications and clinical considerations ⬇️

Control of MHC II antigen presentation by ubiquitination.

Control of MHC class II antigen presentation in dendritic cells: a balance between creative and destructive forces.

Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination.

Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens

Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1 ⬇️

Cutting edge: B220+CCR9- dendritic cells are not plasmacytoid dendritic cells but are precursors of conventional dendritic cells.

Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells

DEC-205 is a cell surface receptor for CpG oligonucleotides

DNA-based probes for flow cytometry analysis of endocytosis and recycling

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism ⬇️

Dendritic Cell Migration and Antigen Presentation Are Coordinated by the Opposing Functions of the Tetraspanins CD82 and CD37.

Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens

Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system.

Different cross-presentation pathways in steady-state and inflammatory dendritic cells

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation.

Differential expression of pathogen-recognition molecules between dendritic cell subsets revealed by plasma membrane proteomic analysis

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells

Downregulation of MHC Class I Expression by Influenza A and B Viruses

Editorial overview: New proteins, cellular processes and intercellular interactions involved in antigen presentation

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

Endolysosomal proteases and their inhibitors in immunity.

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

Factors determining the spontaneous activation of splenic dendritic cells in culture

Found in translation: the human equivalent of mouse CD8+ dendritic cells

GM-CSF increases cross-presentation and CD103 expression by mouse CD8⁺ spleen dendritic cells

HLA‐B27 (B*2701) specificity for peptides lacking Arg2 is determined by polymorphism outside the B pocket ⬇️

Hepatitis B virus-like particles access major histocompatibility class I and II antigen presentation pathways in primary dendritic cells

Hold on, the monocytes are coming!

How MR1 Presents a Pathogen Metabolic Signature to Mucosal-Associated Invariant T (MAIT) Cells.

Hydrocortisone prevents immunosuppression by interleukin-10+ natural killer cells after trauma-hemorrhage

IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

Induction of antigen-specific effector-phase tolerance following vaccination against a previously ignored B-cell lymphoma

Inflammation conditions mature dendritic cells to retain the capacity to present new antigens but with altered cytokine secretion function.

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

Introducing this special issue

Invariant chain controls the activity of extracellular cathepsin L.

Is it a DC, is it an NK? No, it's an IKDC

Life cycle, migration and antigen presenting functions of spleen and lymph node dendritic cells: limitations of the Langerhans cells paradigm

Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

MARCH ligases in immunity

MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway

MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation

MR1 antigen presentation to MAIT cells: new ligands, diverse pathways?

MR1 presentation of vitamin B-based metabolite ligands.

Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα)

Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming