Filtros de búsqueda

Lista de obras de Maria G Castro

A novel bicistronic high-capacity gutless adenovirus vector that drives constitutive expression of herpes simplex virus type 1 thymidine kinase and tet-inducible expression of Flt3L for glioma therapeutics

artículo científico publicado en 2010

A novel combination of promoter and enhancers increases transgene expression in vascular smooth muscle cells in vitro and coronary arteries in vivo after adenovirus-mediated gene transfer

artículo científico publicado en 2003

ANGI-16IN VIVO AND IN VITRO STUDIES SHOW THAT BRAIN DERIVED ENDOTHELIAL CELLS STIMULATE MIGRATION OF HUMAN, MOUSE AND RAT GLIOMA CELLS.

artículo científico publicado en 2015

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

artículo científico publicado en 2016

ATRX mutations and glioblastoma: Impaired DNA damage repair, alternative lengthening of telomeres, and genetic instability.

artículo científico publicado en 2016

Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain

artículo científico publicado en 2001

Adenoviral vector-mediated gene therapy for gliomas: coming of age.

artículo científico publicado en 2014

Adenoviral vectors encoding tumor necrosis factor-alpha and FasL induce apoptosis of normal and tumoral anterior pituitary cells

artículo científico publicado en 2006

Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types

artículo científico publicado en 2002

Adenovirus expression of IL-1 and NF-kappaB inhibitors does not inhibit acute adenoviral-induced brain inflammation, but delays immune system-mediated elimination of transgene expression.

artículo científico publicado en 2003

Adenovirus vector-mediated delivery of the prodrug-converting enzyme carboxypeptidase G2 in a secreted or GPI-anchored form: High-level expression of this active conditional cytotoxic enzyme at the plasma membrane

artículo científico publicado en 2002

Adenovirus vectors to transfer genes into neurones: implications for gene therapy of neurological disorders.

artículo científico publicado en 1994

Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes

artículo científico publicado en 2009

Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU.

artículo científico publicado en 2001

Adenovirus-mediated gene transfer in the ovine pituitary gland is associated with hypophysitis

artículo científico publicado en 2002

Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition

artículo científico publicado en 2001

Adenovirus-mediated gene transfer of transforming growth factor-beta3, but not transforming growth factor-beta1, inhibits constrictive remodeling and reduces luminal loss after coronary angioplasty.

artículo científico publicado en 2003

Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas

artículo científico publicado en 2000

Adenoviruses encoding HPRT correct biochemical abnormalities of HPRT-deficient cells and allow their survival in negative selection medium

artículo científico publicado en 1999

Antibodies to neuropeptide precursors expressed as fusion proteins in E. coli their use to examine neuropeptide biosynthetic pathways, intracellular trafficking and physiological activities ⬇️

artículo científico publicado el 1 de junio de 1992

Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression

artículo científico publicado en 2009

Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM

artículo científico publicado en 2014

B cells are critical to T-cell-mediated antitumor immunity induced by a combined immune-stimulatory/conditionally cytotoxic therapy for glioblastoma.

artículo científico publicado en 2011

Biocontrol and PGPR Features in Native Strains Isolated from Saline Soils of Argentina

article

Biosynthesis of corticotrophin-releasing hormone (CRH) in mouse corticotrophic tumour cells expressing the human proCRH gene: intracellular storage and regulated secretion

artículo científico publicado en 1991

Biosynthesis of corticotropin-releasing hormone in human T-lymphocytes

artículo científico publicado en 1993

Blockade of cell volume regulatory protein NKCC1 increases TMZ-induced glioma apoptosis and reduces astrogliosis

artículo científico publicado en 2020

Blockade of mTOR signaling via rapamycin combined with immunotherapy augments antiglioma cytotoxic and memory T-cell functions.

artículo científico publicado en 2014

Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier!

artículo científico publicado en 2014

CD20, CD3, and CD40 ligand microclusters segregate three-dimensionally in vivo at B-cell-T-cell immunological synapses after viral immunity in primate brain

artículo científico publicado en 2008

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.

artículo científico publicado en 2016

Cell type-specific adenoviral transgene expression in the intact ovine pituitary gland after stereotaxic delivery: an in vivo system for long-term multiple parameter evaluation of human pituitary gene therapy.

artículo científico publicado en 2001

Cell type-specific expression from viral promoters within replication-deficient adenovirus recombinants in primary neocortical cultures.

artículo científico publicado en 1995

Cell type-specific expression in brain cell cultures from a short human cytomegalovirus major immediate early promoter depends on whether it is inserted into herpesvirus or adenovirus vectors

artículo científico publicado en 1997

Cell-type specific expression in the pituitary: physiology and gene therapy.

artículo científico publicado en 1999

Cell-type-specific and regulatable transgenesis in the adult brain: adenovirus-encoded combined transcriptional targeting and inducible transgene expression

artículo científico publicado en 2000

Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK.

artículo científico publicado en 2000

Challenges in the evaluation, consent, ethics and history of early clinical trials - Implications of the Tuskegee 'trial' for safer and more ethical clinical trials

artículo científico publicado en 2009

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

artículo científico publicado en 2016

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

artículo científico publicado en 1999

Co-localisation of autoimmune antibodies specific for double stranded DNA with procorticotrophin-releasing hormone within the nucleus of stably transfected CHO-K1 cells.

artículo científico publicado en 1995

Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.

artículo científico publicado en 2005

Combining cytotoxic and immune-mediated gene therapy to treat brain tumors

artículo científico publicado en 2005

Consensus guidelines for the detection of immunogenic cell death

artículo científico publicado en 2014

Corticotrophin-releasing hormone receptor type 1: generation and characterization of polyclonal antipeptide antibodies and their localization in pituitary cells and cortical neurones in vitro

artículo científico publicado en 1996

Corticotropin-releasing (CRH) activity of thymic peptides on CRH-insensitive corticotropic tumor cells.

artículo científico publicado en 1993

Cracking the glioma-NK inhibitory code: toward successful innate immunotherapy

artículo científico publicado en 2014

Current and future strategies for the treatment of malignant brain tumors.

artículo científico publicado en 2003

Cytotoxic immunological synapses do not restrict the action of interferon-γ to antigenic target cells.

artículo científico publicado en 2012

Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells

artículo científico publicado en 2001

Dendritic cell-based immunotherapy for glioma: multiple regimens and implications in clinical trials

artículo científico publicado en 2013

Differential Effect of Aging on Serum Levels of Prolactin and -Melanotropin in Rats

artículo científico publicado en 1991

Differentiation and transcription factor gene therapy in experimental parkinson's disease: sonic hedgehog and Gli-1, but not Nurr-1, protect nigrostriatal cell bodies from 6-OHDA-induced neurodegeneration.

artículo científico publicado en 2004

Diminished Diurnal Secretion of Corticosterone in Aging Female but Not Male Rats

artículo científico publicado en 1989

Direct regulation of GnRH transcription by CRF-like peptides in an immortalized neuronal cell line

artículo científico publicado en 1998

Effect of the corticotrophin releasing hormone precursor on interleukin-6 release by human mononuclear cells

artículo científico publicado en 1997

Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells.

artículo científico publicado en 2006

Effectiveness and preclinical safety profile of doxycycline to be used "off-label" to induce therapeutic transgene expression in a phase I clinical trial for glioma

artículo científico publicado en 2013

Effects of corticotrophin-releasing factor and arginine-vasopressin on proopiomelanocortin (POMC) mRNA levels, release and storage of adrenocorticotrophin from mouse anterior pituitary cells

artículo científico publicado en 1993

Effects of ectopic decorin in modulating intracranial glioma progression in vivo, in a rat syngeneic model

artículo científico publicado en 2004

Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination

artículo científico publicado en 2001

Electrophysiological evidence against a neurotransmitter role of corticotropin-releasing hormone (CRH) in primary somatosensory cortex

artículo científico publicado en 1998

Engineering the brain tumor microenvironment enhances the efficacy of dendritic cell vaccination: implications for clinical trial design.

artículo científico publicado en 2011

Estrogens sensitize anterior pituitary gland to apoptosis

artículo científico publicado en 2004

Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures

article

Exogenous fms-like tyrosine kinase 3 ligand overrides brain immune privilege and facilitates recognition of a neo-antigen without causing autoimmune neuropathology

artículo científico publicado en 2010

Expression and partial purification of human prolactin in Escherichia coli.

artículo científico publicado en 1991

Expression of Biologically Active Procorticotrophin-Releasing Hormone (proCRH) in Stably Transfected CHO-K1 Cells: Characterization of Nuclear proCRH

scientific article published on 01 April 1995

Expression of biologically active human pre-procorticotropin releasing hormone in E. coli: characterization and purification

artículo científico publicado en 1990

Expression of prolactin receptors and regulation of cell proliferation by prolactin, corticotropin-releasing factor, and corticosterone in a neuroblastoma cell line

artículo científico publicado en 2002

Expression of transgenes in normal and neoplastic anterior pituitary cells using recombinant adenoviruses: long term expression, cell cycle dependency, and effects on hormone secretion

artículo científico publicado en 1997

Fas ligand-transfected myoblasts and islet cell transplantation.

artículo científico publicado en 2000

FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

artículo científico publicado en 1998

Fitness, insulin sensitivity, and frontal lobe integrity in adults with overweight and obesity.

artículo científico publicado en 2016

Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model.

artículo científico publicado en 2007

Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits.

artículo científico publicado en 2008

Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain

artículo científico publicado en 2006

Gene Therapy for the Treatment of Neurological Disorders: Central Nervous System Neoplasms.

artículo científico publicado en 2016

Gene therapy and targeted toxins for glioma

article

Gene therapy and virotherapy: novel therapeutic approaches for brain tumors ⬇️

artículo científico publicado el 1 de octubre de 2010

Gene therapy continues to make progress: clinical and regulatory perspectives

artículo científico publicado en 2009

Gene therapy for Parkinson's disease: recent achievements and remaining challenges.

artículo científico publicado en 2001

Gene therapy for brain cancer: combination therapies provide enhanced efficacy and safety.

artículo científico publicado en 2009

Gene therapy for brain tumors: basic developments and clinical implementation

artículo científico publicado en 2012

Gene therapy for inherited neurological disorders: towards therapeutic intervention in the Lesch-Nyhan syndrome.

artículo científico publicado en 1998

Gene therapy for liver transplantation using adenoviral vectors: CD40-CD154 blockade by gene transfer of CD40Ig protects rat livers from cold ischemia and reperfusion injury

artículo científico publicado en 2004

Gene therapy for pituitary tumors.

artículo científico publicado en 2005

Gene therapy for pituitary tumours.

artículo científico publicado en 1999

Gene therapy strategies for intracranial tumours: glioma and pituitary adenomas.

artículo científico publicado en 2000

Gene therapy strategies for the treatment of pituitary tumours

artículo científico publicado en 1999

Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics.

artículo científico publicado en 2010

Gene therapy-mediated reprogramming tumor infiltrating T cells using IL-2 and inhibiting NF-κB signaling improves the efficacy of immunotherapy in a brain cancer model

artículo científico publicado en 2012

Gene transfer into cultured bovine ciliary epithelial cells using adenovirus vectors

artículo científico publicado en 1996

Gene transfer into enteric neurons of the rat small intestine in organ culture using a replication defective recombinant herpes simplex virus type 1 (HSV1) vector, but not recombinant adenovirus vectors

artículo científico publicado en 1997

Gene transfer into neural cells in vitro using adenoviral vectors

artículo científico publicado en 2008

Gene transfer into rat brain using adenoviral vectors.

artículo científico publicado en 2010

Generation and characterization of an antiserum reactive with a proteolytic processing site within rat procorticotrophin-releasing hormone

artículo científico publicado en 1995

Generation of a recombinant herpes simplex virus type 1 expressing the rat corticotropin- releasing hormone precursor: endoproteolytic processing, intracellular targeting and biological activity

artículo científico publicado en 1999

Glioma trials and viral tribulations: can anything be concluded from non-controlled trials?

artículo científico publicado en 2014

HG-02ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS GENETIC STABILITY IN GLIOBLASTOMA.

artículo científico publicado en 2015

HG-03A NOVEL MOUSE MODEL OF YOUNG ADULT GLIOBLASTOMA: IN VIVO EXPRESSION OF MUTATED IDH1 (R132H) GENE USING THE SLEEPING BEAUTY TRANSPOSASE SYSTEM.

artículo científico publicado en 2015

HSV1 vectors to study protein targeting in neurones: are glycosyl-phosphatidylinositol anchors polarized targeting signals in neurones?

artículo científico publicado en 1994

Hemispherical Pediatric High-Grade Glioma: Molecular Basis and Therapeutic Opportunities

artículo científico publicado en 2020

Herpes simplex virus 1 (HSV-1) helper co-infection affects the distribution of an amplicon encoded protein in glia.

artículo científico publicado en 1994

Herpes simplex virus type 1 thymidine kinase sequence fused to the lacz gene increases levels of {beta}-galactosidase activity per genome of high-capacity but not first-generation adenoviral vectors in vitro and in vivo.

artículo científico publicado en 2008

High-Capacity Adenovirus Vector-Mediated Anti-Glioma Gene Therapy in the Presence of Systemic Antiadenovirus Immunity.

artículo científico publicado en 2008

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme

scientific article published on 11 February 2019

High-capacity adenovirus vector-mediated anti-glioma gene therapy in the presence of systemic antiadenovirus immunity.

artículo científico publicado en 2008

High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain

artículo científico publicado en 2002

Histones and related preparations interfere with immunoassays for peptide hormones

scientific article published on 01 July 1993

Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial

artículo científico publicado en 2010

Human gene therapy and imaging in neurological diseases

artículo científico publicado en 2005

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

artículo científico publicado en 2019

IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome.

artículo científico publicado en 2008

Identification and Visualization of CD8+ T Cell Mediated IFN-γ Signaling in Target Cells during an Antiviral Immune Response in the Brain ⬇️

artículo científico publicado el 29 de agosto de 2011

Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy

artículo científico publicado en 2016

Immune regulation of transgene expression in the brain: B cells regulate an early phase of elimination of transgene expression from adenoviral vectors

artículo científico publicado en 2006

Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of neuroimmune interactions

artículo científico publicado en 2007

Immune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cells

artículo científico publicado en 2012

Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells.

artículo científico publicado en 2006

Immunology of neurological gene therapy: how T cells modulate viral vector-mediated therapeutic transgene expression through immunological synapses

artículo científico publicado en 2007

Immunoreactive delta sleep-inducing peptide secretion from mouse dissociated, anterior pituitary cells: regulation by corticotropin-releasing factor and arginine vasopressin

artículo científico publicado en 1989

Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

artículo científico publicado en 2017

Improved distribution of small molecules and viral vectors in the murine brain using a hollow fiber catheter.

scientific article published on September 2007

In vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells.

artículo científico publicado en 2008

In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system.

artículo científico publicado en 2005

Infiltrating CTLs in human glioblastoma establish immunological synapses with tumorigenic cells

artículo científico publicado en 2009

Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression.

artículo científico publicado en 2004

Inhibition of 2-Hydroxyglutarate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity in Mice

artículo científico publicado en 2020

Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.

artículo científico publicado en 1999

Intracellular Retention of the Corticotrophin-releasing Hormone (CRH) Precursor Within COS-7 Cells

artículo científico publicado en 1998

Intracellular compartmentalisation of procorticotrophin releasing hormone

artículo científico publicado en 1993

Intracellular trafficking of prohormones and proneuropeptides: cell type-specific sorting and targeting

artículo científico publicado en 1997

Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression.

artículo científico publicado en 2007

Intrapituitary adenoviral administration of 7B2 can extend life span and reverse endocrinological deficiencies in 7B2 null mice

artículo científico publicado en 2002

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

artículo científico publicado en 2015

Kupfer-type immunological synapse characteristics do not predict anti-brain tumor cytolytic T-cell function in vivo.

artículo científico publicado en 2010

Lack of humoral immune response to the tetracycline (Tet) activator in rats injected intracranially with Tet-off rAAV vectors

artículo científico publicado en 2010

Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.

artículo científico publicado en 2014

Marmosets as a preclinical model for testing "off-label" use of doxycycline to turn on Flt3L expression from high-capacity adenovirus vectors

artículo científico publicado en 2014

Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1.

artículo científico publicado en 2017

Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy.

artículo científico publicado en 2014

Mitochondrial haplogroup T is negatively associated with the status of elite endurance athlete

artículo científico publicado en 2007

Molecular therapy in a model neuroendocrine disease: developing clinical gene therapy for pituitary tumours.

artículo científico publicado en 2001

Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas

artículo científico publicado en 2016

Mutant ATRX: uncovering a new therapeutic target for glioma.

artículo científico publicado en 2018

Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer

artículo científico publicado en 2017

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres

artículo científico publicado en 2018

Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity

artículo científico publicado en 2014

Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells

artículo científico publicado en 2016

Neocortical neuronal polarity: targeting of a foreign protein linked to a glycosyl-phosphatidylinositol (GPI) anchor in postmitotic neurons and polarized distribution of a marker of the trans-Golgi network (TGN 38).

artículo científico publicado en 1993

Neuro-oncology: The long and winding road--gene therapy for glioma

artículo científico publicado en 2013

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity

artículo científico publicado en 1999

Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease.

artículo científico publicado en 2004

Neuropeptide gene transfer into neuronal and glial cell lines

artículo científico publicado en 1994

Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders

artículo científico publicado en 2003

Normalization of wound healing and diabetic markers in organ cultured human diabetic corneas by adenoviral delivery of c-Met gene

artículo científico publicado en 2009

Nuclear and cytoplasmic localisation of procorticotrophin releasing hormone in transfected CHO-K1 cells.

artículo científico publicado en 1994

Nuclear localisation of corticotrophin releasing hormone (CRH) in transfected CHO-K1 cells

artículo científico publicado en 1993

Nuclear translocation of neuropeptides: possible nuclear roles

artículo científico publicado en 1995

On the stimulatory nature of the control of MSH secretion in ducks

artículo científico publicado en 1986

One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications.

artículo científico publicado en 2007

Overview of current immunotherapeutic strategies for glioma

artículo científico publicado en 2015

PTPS-15ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS NON-HOMOLOGOUS END JOINING DNA REPAIR IN GLIOMA.

artículo científico publicado en 2015

Photoperiodic regulation of prolactin gene expression in the Syrian hamster by a pars tuberalis-derived factor.

artículo científico publicado en 2001

Piry virus antibodies in inhabitants of Rio de Janeiro

artículo científico publicado en 1993

Platelets mediate cytotoxic T lymphocyte-induced liver damage

artículo científico publicado en 2005

Polarity development and synaptogenesis in low density primary cultures of neocortex. Use of herpes simplex virus-1 vectors to transfer genes into postmitotic neurons

artículo científico publicado en 1993

Polarized Distribution of the Trans-Golgi Network Marker TGN38 During the In Vitro Development of Neocortical Neurons: Effects of Nocodazole and Brefeldin A

article

Politically correct gene therapy? A "clean environment" improves gene delivery to the brain!

artículo científico publicado en 1999

Post-translational processing of proopiomelanocortin in the pituitary and in the brain

artículo científico publicado en 1997

Potential impact of a presumed increase in the biting activity of dengue-virus-infected Aedes aegypti (Diptera: Culicidae) females on virus transmission dynamics.

artículo científico publicado en 2011

Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn "On" Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model

artículo científico publicado en 2016

Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy

artículo científico publicado en 2014

Prediction of protein antigenic sites in human corticotrophin-releasing hormone precursor

artículo científico publicado en 1993

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

artículo científico publicado en 2001

Presence of pro-vasopressin mRNA, neurophysin and arginine vasopressin in mouse anterior pituitary cells and the AtT-20 corticotrophic tumour cell line

artículo científico publicado en 1988

Pro-opiomelanocortin and pro-vasopressin converting enzyme in pituitary secretory vesicles

artículo científico publicado en 1988

Processing of Procorticotropin-Releasing Hormone (Pro-CRH): Molecular Forms of CRH in Normal and Preeclamptic Pregnancy1

scientific article published on 01 February 2000

Procorticotrophin releasing hormone is endoproteolytically processed by the prohormone convertase PC2 but not by PC1 within stably transfected CHO-K1 cells

artículo científico publicado en 1996

Procorticotrophin-releasing hormone: endoproteolytic processing and differential release of its derived peptides within AtT20 cells.

artículo científico publicado en 1998

Production and release of corticotropin releasing hormone (CRH) from AtT-20 cells stably transfected with the human CRH gene

artículo científico publicado en 1990

Progesterone antagonizes the permissive action of estradiol on tumor necrosis factor-alpha-induced apoptosis of anterior pituitary cells.

artículo científico publicado en 2004

Progress and challenges in viral vector-mediated gene transfer to the brain.

artículo científico publicado en 2002

Progress in gene therapy for neurological disorders.

artículo científico

Prohormone and proneuropeptide synthesis and secretion.

artículo científico publicado en 1997

Prospects of biological and synthetic pharmacotherapies for glioblastoma

scientific article published on 20 January 2020

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

scientific article published on 30 July 2020

Pushing the limits of glioma resection using electrophysiologic brain mapping

artículo científico publicado en 2012

Quantification of high-capacity helper-dependent adenoviral vector genomes in vitro and in vivo, using quantitative TaqMan real-time polymerase chain reaction.

artículo científico publicado en 2006

Real-time imaging of gene promoter activity using an adenoviral reporter construct demonstrates transcriptional dynamics in normal anterior pituitary cells.

artículo científico publicado en 2003

Recent advances and future of immunotherapy for glioblastoma

artículo científico publicado en 2016

Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses.

artículo científico publicado en 2006

Regulated, adenovirus-mediated delivery of tyrosine hydroxylase suppresses growth of estrogen-induced pituitary prolactinomas

artículo científico publicado en 2001

Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a disco

artículo científico publicado en 2016

Safety Profile of Gutless Adenovirus Vectors Delivered into the Normal Brain Parenchyma: Implications for a Glioma Phase 1 Clinical Trial ⬇️

artículo científico publicado el 5 de septiembre de 2012

Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma ⬇️

artículo científico publicado el 9 de febrero de 2013

Simultaneous detection of amplicon and HSV-1 helper encoded proteins reveals that neurons and astrocytoma cells do express amplicon-borne transgenes in the absence of synthesis of virus immediate early proteins

artículo científico publicado en 1995

Single vs. combination immunotherapeutic strategies for glioma.

artículo científico publicado en 2017

Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment

artículo científico publicado en 2016

Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses

artículo científico publicado en 2005

Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo

artículo científico publicado en 2000

Studies on the prolactin-releasing mechanism of histones H2A and H2B

artículo científico publicado en 2000

Subcellular post-transcriptional targeting: delivery of an intracellular protein to the extracellular leaflet of the plasma membrane using a glycosyl-phosphatidylinositol (GPI) membrane anchor in neurons and polarised epithelial cells

artículo científico publicado en 2000

Survival and Proliferation of Neural Progenitor-Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism

artículo científico publicado en 2016

Switching on and off transgene expression within lactotrophic cells in the anterior pituitary gland in vivo

artículo científico publicado en 2001

Synaptogenesis and distribution of presynaptic axonal varicosities in low density primary cultures of neocortex: an immunocytochemical study utilizing synaptic vesicle-specific antibodies, and an electrophysiological examination utilizing whole cell

article

Synthetic HDL Nanoparticles Delivering Docetaxel and CpG for Chemoimmunotherapy of Colon Adenocarcinoma

artículo científico publicado en 2020

Synthetic high-density lipoprotein nanodiscs for personalized immunotherapy against gliomas

scientific article published on 21 May 2020

Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy

artículo científico publicado en 2020

T cells' immunological synapses induce polarization of brain astrocytes in vivo and in vitro: a novel astrocyte response mechanism to cellular injury

artículo científico publicado en 2008

Targeted toxins for glioblastoma multiforme: pre-clinical studies and clinical implementation.

artículo científico publicado en 2011

Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models

artículo científico publicado en 2014

The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas

artículo científico publicado en 2020

The Long and Winding Road: From the High-Affinity Choline Uptake Site to Clinical Trials for Malignant Brain Tumors

artículo científico publicado en 2016

The regulation of the corticomelanotropic cell activity in Aves--II. Effect of various peptides on the release of ACTH from dispersed, perfused duck pituitary cells

artículo científico publicado en 1986

The regulation of the corticomelanotropic cell activity in aves. III--Effect of various peptides on the release of MSH from dispersed, perfused duck pituitary cells. Cosecretion of ACTH with MSH.

artículo científico publicado en 1988

The use of inclusion bodies, isolated from Escherichia coli expressing corticotrophin-releasing hormone precursor, to raise specific antibodies against the neuropeptide moiety

artículo científico publicado en 1990

The value of EGFRvIII as the target for glioma vaccines.

artículo científico publicado en 2014

Therapeutic efficacy of immune stimulatory thymidine kinase and fms-like tyrosine kinase 3 ligand (TK/Flt3L) gene therapy in a mouse model of high grade brainstem glioma

artículo científico publicado en 2020

Thymosin peptides stimulate corticotropin release by a calcium-dependent mechanism

artículo científico publicado en 1993

Thymus-pituitary interactions during ageing

artículo científico publicado en 1993

Tolerance to cardiac allografts via local and systemic mechanisms after adenovirus-mediated CTLA4Ig expression.

artículo científico publicado en 2000

Towards global and long-term neurological gene therapy: unexpected transgene dependent, high-level, and widespread distribution of HSV-1 thymidine kinase throughout the CNS.

artículo científico publicado en 2001

Transcriptional targeting to anterior pituitary lactotrophic cells using recombinant adenovirus vectors in vitro and in vivo in normal and estrogen/sulpiride-induced hyperplastic anterior pituitaries

artículo científico publicado en 2000

Transmembrane signals mediating adrenocorticotropin release from mouse anterior pituitary cells

artículo científico publicado en 1989

Transposon mediated integration of plasmid DNA into the subventricular zone of neonatal mice to generate novel models of glioblastoma

artículo científico publicado en 2015

Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand

artículo científico publicado en 1999

Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials

artículo científico publicado en 2008

Uptake of alpha-(L)-iduronidase produced by retrovirally transduced fibroblasts into neuronal and glial cells in vitro

artículo científico publicado en 1997

Use of gene transfer to study post-translational modifications of neuropeptides in cell lines

artículo científico publicado en 1994

Use of recombinant adenovirus for gene transfer into the rat brain. Evaluation of gene transfer efficiency, toxicity, and inflammatory and immune reactions

artículo científico publicado en 2003

Use of recombinant herpes simplex virus type 1 vectors for gene transfer into tumour and normal anterior pituitary cells

artículo científico publicado en 1998

Use of recombinant vectors derived from herpes simplex virus 1 mutant tsK for short-term expression of transgenes encoding cytoplasmic and membrane anchored proteins in postmitotic polarized cortical neurons and glial cells in vitro

artículo científico publicado en 1994

γ-Glutamyl transferase: a marker of nonalcoholic fatty liver disease in patients with the metabolic syndrome.

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda