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Lista de obras de Paul J Hertzog

A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis

scientific article published on 30 April 2019

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

artículo científico publicado en 2017

A human CD2 minigene directs CRE-mediated recombination in T cells in vivo

article

A notch in the toll belt

artículo científico publicado en 2008

A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans

artículo científico publicado en 2018

A structural "star" in interferon gamma signaling

artículo científico publicado en 2019

Aberrant activation of JAK/STAT pathway components in response to G-CSF, interferon-alpha/beta and interferon-gamma in NFS-60 cells

artículo científico publicado en 1996

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

artículo científico publicado en 2008

Adamts-1 is essential for the development and function of the urogenital system

scientific journal article

Administration of imiquimod, an interferon inducer, in asymptomatic human immunodeficiency virus-infected persons to determine safety and biologic response modification

artículo científico publicado en 1998

Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress

scientific article published on 01 November 2004

An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse

artículo científico publicado en 2003

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.

artículo científico publicado en 2011

Animal models in the study of the biological function of genes on human chromosome 21 and their role in the pathophysiology of Down syndrome ⬇️

artículo científico publicado el 1 de enero de 1997

Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta

artículo científico publicado el 5 de agosto de 1992

Antitumour actions of interferons: implications for cancer therapy

artículo científico publicado en 2016

Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis.

artículo científico publicado en 2018

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

article

Binding of interferon-alpha and -beta to a component of the human type I interferon receptor expressed in simian cells

artículo científico publicado en 1996

Biological and chemical studies on 8,9-dihydroxy-8,9-dihydro-aflatoxin B1 and some of its esters ⬇️

artículo científico publicado el 1 de enero de 1980

Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses

artículo científico publicado en 2015

Blocking Monoclonal Antibodies Specific for Mouse IFN-α/β Receptor Subunit 1 (IFNAR-1) from Mice Immunized by In Vivo Hydrodynamic Transfection

article

Brief Report: Identification of a Pathogenic Variant in TREX1 in Early-Onset Cerebral Systemic Lupus Erythematosus by Whole-Exome Sequencing

artículo científico publicado en 2014

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

article

Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster

artículo científico publicado en 2003

Characterization of monoclonal antibodies specific to the transcription factor ETS-2 protein

scientific article published on 01 March 2003

Characterization of the type I interferon locus and identification of novel genes

artículo científico publicado en 2004

Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis.

artículo científico publicado en 2003

Choice of mouse strains for gene targeting.

artículo científico publicado en 2001

CiiiDER: A tool for predicting and analysing transcription factor binding sites

artículo científico publicado en 2019

Cloning and Characterization of Soluble and Transmembrane Isoforms of a Novel Component of the Murine Type I Interferon Receptor, IFNAR 2 ⬇️

artículo científico publicado el 19 de septiembre de 1997

Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

artículo científico publicado en 2019

Comparison of mice born after intracytoplasmic sperm injection with in vitro fertilization and natural mating

artículo científico publicado en 2007

Comparison of the effects of Enovid and α-naphthylisothiocyanate on bromosulphophthalein excretion in Syrian golden hamsters

artículo científico publicado en 1980

Concurrent Host-Pathogen Transcriptional Responses in a Clostridium perfringens Murine Myonecrosis Infection.

artículo científico publicado en 2018

Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo

artículo científico publicado en 2005

Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

artículo científico publicado en 2023

CpG pretreatment enhances antiviral T-cell immunity against cytomegalovirus

artículo científico publicado en 2013

Cutting Edge: Pulmonary Legionella pneumophila Is Controlled by Plasmacytoid Dendritic Cells but Not Type I IFN

artículo científico publicado en 2010

Defining the distinct, intrinsic properties of the novel type I interferon, epsilon.

artículo científico publicado en 2017

Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors

artículo científico publicado en 2002

Desrt, an AT-rich interaction domain family transcription factor gene, is an early marker for nephrogenic mesoderm and is expressed dynamically during mouse limb development

artículo científico publicado en 2001

Detection of cells producing murine interferon-α using antipeptide antibodies

artículo científico publicado en 1994

Different interactions of interferon-alpha subtypes at the surface of epithelial and lymphoid cells

artículo científico publicado el 1 de agosto de 1992

Differential Effect of Several Inducers on Hepatic and Mammary Benzo (A) Pyrene Metabolism in Rat and Hamster

artículo científico publicado en 1981

Differential expression and effects of gp130 cytokines and receptors in prostate cancer cells

artículo científico publicado en 2004

Differentiation-associated changes in mucin glycoprotein antigenicity in mucosa adjacent to rare gastrointestinal tract tumours of non-mucosal origin

artículo científico publicado en 1993

Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

scientific journal article

Down syndrome and mouse models

artículo científico publicado en 1998

Dynamic control of type I IFN signalling by an integrated network of negative regulators

artículo científico

Early T-BET Expression Ensures an Appropriate CD8+ Lineage-Specific Transcriptional Landscape after Influenza A Virus Infection

scientific article published on 21 June 2019

Endogenous interferon-alpha production by differentiating human monocytes regulates expression and function of the IL-2/IL-4 receptor gamma chain.

artículo científico publicado en 2002

Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5

artículo científico publicado en 2003

Ets-2 is induced by oxidative stress and sensitizes cells to H(2)O(2)-induced apoptosis: implications for Down's syndrome

artículo científico publicado en 2001

Ets1 as a marker of malignant potential in gastric carcinoma ⬇️

artículo científico publicado el 1 de octubre de 2003

Ets2 is expressed during morphogenesis of the somite and limb in the mouse embryo

artículo científico publicado en 2002

Expression of a novel family of epitopes on small intestinal mucins in colorectal cancers, adjacent and remote mucosa

scientific article published on 01 January 1992

Expression of large intestinal mucin antigen (LIMA) epitopes in the normal and neoplastic gastrointestinal tract.

artículo científico publicado en 1993

Factors determining the spontaneous activation of splenic dendritic cells in culture

article

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

scientific journal article

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

artículo científico publicado en 2010

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

artículo científico publicado en 2009

GM-CSF-induced autoimmune gastritis in interferon α receptor deficient mice

article

Generation and characterization of neuregulin-2-deficient mice.

artículo científico publicado en 2004

Generation and characterization of recombinant unmodified and phosphorylatable murine IFN-alpha1 in the methylotropic yeast Pichia pastoris.

artículo científico publicado en 2003

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

artículo científico publicado en 2016

Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon

artículo científico publicado en 2014

Glutathione Peroxidase-1 Contributes to the Neuroprotection Seen in the Superoxide Dismutase-1 Transgenic Mouse in Response to Ischemia/Reperfusion Injury

article

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

artículo científico publicado en 2011

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection

artículo científico publicado en 2016

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

artículo científico publicado en 2013

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

artículo científico publicado en 2010

INTERFEROME: the database of interferon regulated genes

artículo científico publicado en 2009

Identification and expression analysis of alternative transcripts of the mouse GA-binding protein (Gabp) subunits alpha and beta1.

artículo científico publicado en 2004

Immunolocalisation of interferon-alpha in hepatitis C patients and its correlation with response to interferon-alpha therapy

scientific article published on 01 November 1994

In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours.

artículo científico publicado en 2013

Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells

artículo científico publicado en 2016

Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis.

artículo científico publicado en 2012

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

artículo científico publicado en 2019

Interferome v2.0: an updated database of annotated interferon-regulated genes

artículo científico publicado en 2012

Interferon epsilon promotes HIV restriction at multiple steps of viral replication

artículo científico publicado en 2017

Interferon-γ: an overview of signals, mechanisms and functions ⬇️

artículo científico publicado el 2 de octubre de 2003

Interferon-ε protects the female reproductive tract from viral and bacterial infection

scientific journal article

Interferons as biomarkers and effectors: lessons learned from animal models.

artículo científico publicado en 2012

Intermittent interferonemia and interferon responses in multiple sclerosis ⬇️

artículo científico publicado el 1 de enero de 1991

Isolation of embryonic fibroblasts and their use in the in vitro characterization of gene function.

artículo científico publicado en 2001

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

scientific journal article

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

artículo científico publicado en 2011

Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons

artículo científico publicado en 2005

Liver plasma membrane enzyme activities following glutaraldehyde fixation ⬇️

artículo científico publicado el 1 de enero de 1976

Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer

artículo científico publicado en 2015

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

artículo científico publicado en 2011

Macrophage lineage phenotypes and osteoclastogenesis—Complexity in the control by GM-CSF and TGF-β

article

Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.

artículo científico publicado en 2004

Mechanism of Interferon Stimulated Gene Induction in HIV-1 Infected Macrophages

artículo científico publicado en 2017

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

artículo científico publicado en 1998

MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response

artículo científico publicado en 2015

Mitochondrially localised MUL1 is a novel modulator of antiviral signaling

artículo científico publicado en 2013

Molecular detection of interferon-alpha expression in multiple sclerosis brain

artículo científico publicado en 1993

Monoclonal antibodies against subunits of yeast mitochondrial H+-ATPase ⬇️

artículo científico publicado el 26 de junio de 1984

Multiple regions within the promoter of the murine Ifnar-2 gene confer basal and inducible expression

artículo científico publicado en 2002

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

artículo científico publicado en 2009

MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.

artículo científico publicado en 2012

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.

artículo científico publicado en 2010

Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis

artículo científico publicado en 2004

Non-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in mice

artículo científico publicado en 2013

Oncofetal expression of the human intestinal mucin glycoprotein antigens in gastrointestinal epithelium defined by monoclonal antibodies ⬇️

artículo científico publicado el 30 de mayo de 1991

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis.

artículo científico publicado en 2003

Overview of cytokine and growth factor review focus on Australia. Preface.

artículo científico publicado en 2013

Overview. Type I interferons as primers, activators and inhibitors of innate and adaptive immune responses

artículo científico publicado en 2012

Overview: Gene Knockouts

article

PROPERTIES AND FUNCTIONS OF THE NOVEL TYPE I INTERFERON EPSILON

scientific article published on 01 June 2019

Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation

artículo científico publicado en 2018

Post‐transcriptional regulation of interferon‐alpha 4 subtype production by lymphoblastoid cells ⬇️

artículo científico publicado el 1 de enero de 1993

Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemia-reperfusion injury

artículo científico publicado en 2006

Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells

artículo científico publicado en 2013

RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

artículo científico publicado en 2017

RNA-eXpress annotates novel transcript features in RNA-seq data.

artículo científico publicado en 2013

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

artículo científico publicado en 2016

Recent advances in cytokines, cytokine receptors and signal transduction

artículo científico publicado en 1998

Regulation of H3K4me3 at Transcriptional Enhancers Characterizes Acquisition of Virus-Specific CD8+ T Cell-Lineage-Specific Function

artículo científico publicado en 2017

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

artículo científico publicado en 2008

Role of interferons in the regulation of cell proliferation, differentiation, and development

artículo científico publicado en 1994

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine

artículo científico publicado en 1999

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

artículo científico publicado en 2008

Sculpting the immune response to infection ⬇️

artículo científico publicado el 20 de junio de 2011

Signaling Molecules Affecting Immune Response

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape

scientific article published on 22 July 2012

Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock

artículo científico publicado en 2014

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

artículo científico publicado en 2014

Structure-function studies based on in vitro expression

artículo científico publicado en 1995

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2 ⬇️

artículo científico publicado el 13 de julio de 2011

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

artículo científico publicado en 2006

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

artículo científico publicado en 2005

Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-Resistant Pseudomonas aeruginosa

artículo científico publicado en 2019

Systems biology of interferon responses.

artículo científico publicado en 2011

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

artículo científico publicado en 2007

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

artículo científico publicado en 2009

Targeting of the ETS factor GABPalpha disrupts neuromuscular junction synaptic function.

artículo científico publicado en 2007

The ETS transcription factor GABPalpha is essential for early embryogenesis

artículo científico publicado en 2004

The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney.

artículo científico publicado en 2011

The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death

artículo científico publicado en 2013

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

artículo científico publicado en 2016

The adenoma-carcinoma sequence in the colorectum--early appearance of a hierarchy of small intestinal mucin antigen (SIMA) epitopes and correlation with malignant potential.

artículo científico publicado en 1992

The apparent inhibition of urothelial DNA synthesis in neonatal rats by dietary saccharin

artículo científico publicado en 1981

The binding of 7,12-dimethylbenz[a]anthracene to mammary gland macromolecules in the hamster:effects of Enovid feeding or transplacental exposure to diethylstilboestrol

artículo científico publicado en 1981

The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome

artículo científico publicado en 2003

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

artículo científico publicado en 2013

The effect of norethynodrel-mestranol pretreatment on hepatic metabolism of 7,12-dimethylbenz(a)anthracene in rats and hamsters

scientific article published on 01 June 1980

The failure of chronically administered saccharin to stimulate bladder epithelial DNA synthesis in F0 rats

artículo científico publicado en 1981

The genomic profile of the cerebral cortex after closed head injury in mice: effects of minocycline

artículo científico publicado en 2008

The role of Ets2 transcription factor in the induction of microRNA-155 (miR-155) by lipopolysaccharide and its targeting by interleukin-10

artículo científico publicado en 2013

The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone.

artículo científico publicado en 2013

The role of type I interferons in TLR responses.

artículo científico publicado en 2007

Tissue-specific overexpression of the HSA21 gene GABPalpha: implications for DS.

artículo científico publicado en 2004

Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.

artículo científico publicado en 2010

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

artículo científico publicado en 2017

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

artículo científico publicado en 2014

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.

artículo científico publicado en 2009

Type I interferon receptors: biochemistry and biological functions.

artículo científico publicado en 2007

Type I interferons mediate the lipopolysaccharide induction of macrophage cyclin D2.

artículo científico publicado en 2000

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection

artículo científico publicado en 2011

Type I-IFNs control GVHD and GVL responses after transplantation

article

Type-I interferon signalling through IFNAR1 plays a deleterious role in the outcome after stroke.

artículo científico publicado en 2017

Ultraviolet-induced apoptosis in embryonic stem cells in vitro

artículo científico publicado en 2006

Viruses 'chew the fat'!?

artículo científico publicado en 2014

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

artículo científico publicado en 2012

α-Naphthyl-isothiocyanate-induced cholestasis in the rat: studies of liver plasma membrane enzymes ⬇️

artículo científico publicado el 1 de enero de 1975

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