Lista de obras - Ashley Buckle - Dominio Público Uruguay

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily

artículo científico publicado en 2021

A colostrum trypsin inhibitor gene expressed in the Cape fur seal mammary gland during lactation

artículo científico publicado en 2015

A common fold mediates vertebrate defense and bacterial attack

artículo científico publicado en 2007

A structural basis for loop C-sheet polymerization in serpins

artículo científico publicado en 2008

A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase

artículo científico publicado en 2002

A structural model for GroEL-polypeptide recognition

artículo científico publicado en 1997

ARCHER – An Enabler of Research Data Management

ARCHER – e-Research Tools for Research Data Management

An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes ⬇️

artículo científico publicado el 8 de abril de 2011

An overview of the serpin superfamily

artículo científico publicado en 2006

CLIMS: Crystallography Laboratory Information Management System

artículo científico publicado en 2004

COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity

artículo científico publicado en 2008

Catalytic diversity and cell wall binding repeats in the phage-encoded endolysins

scientific article published on 13 November 2018

Chiminey: Reliable Computing and Data Management Platform in the Cloud

Circumventing the stability-function trade-off in an engineered FN3 domain

artículo científico publicado en 2016

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

artículo científico publicado en 2014

Computational Methods for Studying Serpin Conformational Change and Structural Plasticity

scientific article published on 01 January 2011

Consensus protein design

artículo científico publicado en 2016

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans

artículo científico publicado en 2005

Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins.

artículo científico

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4

scientific article published on 16 July 2019

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

artículo científico publicado en 2012

Crystallization and preliminary crystallographic studies of a SAM domain at the C-terminus of human p73α

artículo científico publicado en 2000

Crystallographic and Molecular Dynamics Analysis of Loop Motions Unmasking the Peptidoglycan-Binding Site in Stator Protein MotB of Flagellar Motor

artículo científico publicado en 2011

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

scientific article published on 18 September 2019

Design of highly stable functional GroEL minichaperones.

artículo científico publicado en 1999

Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

scientific article published on 04 March 2020

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics

artículo científico publicado en 2016

Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC

artículo científico publicado en 2015

EGM: encapsulated gene-by-gene matching to identify gene orthologs and homologous segments in genomes

artículo científico publicado en 2010

Energetic and structural analysis of the role of tryptophan 59 in FKBP12

artículo científico publicado en 2003

Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

artículo científico publicado en 2022

Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex

artículo científico publicado en 2012

Federated repositories of X-ray diffraction images

artículo científico publicado en 2008

From minichaperone to GroEL 1: information on GroEL-polypeptide interactions from crystal packing of minichaperones.

artículo científico publicado en 2000

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

artículo científico publicado en 2007

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases

artículo científico publicado en 2017

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

scientific article published on 30 August 2018

High-throughput protein structure determination using grid computing

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

artículo científico publicado en 2015

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

artículo científico publicado en 2003

Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition

artículo científico publicado en 2020

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics

article

Interactive visualization tools for the structural biologist

artículo científico publicado en 2013

Intrinsic limitations in mainstream methods of identifying network motifs in biology

scientific article published on 29 April 2020

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors

artículo científico publicado en 2019

KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.

artículo científico publicado en 2016

Laboratory evolution of protein conformational dynamics.

artículo científico publicado en 2017

Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type

artículo científico publicado en 2002

MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography

artículo científico publicado en 2010

Managing and mining protein crystallization data.

artículo científico publicado en 2006

Mapping the pathway and dynamics of bestatin inhibition of the Plasmodium falciparum M1 aminopeptidase, PfA-M1

article

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network

artículo científico publicado en 2011

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

artículo científico publicado en 2013

Membrane proteins of Pseudoalteromonas tunicata during the transition from planktonic to extracellular matrix-adherent state

artículo científico publicado en 2011

Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity

artículo científico publicado en 2015

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

artículo científico publicado en 2013

MrGrid: a portable grid based molecular replacement pipeline

artículo científico publicado en 2010

Operation of the Australian Store.Synchrotron for macromolecular crystallography

artículo científico publicado en 2014

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.

artículo científico publicado en 2014

PLP-dependent enzymes

artículo científico publicado en 2014

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins

artículo científico publicado en 2016

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins

artículo científico publicado en 2016

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins ⬇️

artículo científico publicado el 8 de noviembre de 2010

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif

scientific article published in PLoS ONE

Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed.

artículo científico publicado en 2018

Previously Hidden Dynamics at the TCR-pMHC Interface Revealed

Prodepth: predict residue depth by support vector regression approach from protein sequences only

artículo científico publicado en 2009

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function

artículo científico publicado en 2018

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium.

artículo científico publicado en 2006

REFOLD: an analytical database of protein refolding methods

artículo científico publicado en 2005

REFOLDdb: a new and sustainable gateway to experimental protocols for protein refolding

artículo científico publicado en 2017

Reactive centre loop dynamics and serpin specificity

artículo científico publicado en 2019

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

artículo científico publicado en 2018

Recombinant protein quality evaluation: proposal for a minimal information standard

artículo científico publicado en 2011

Refolding Your Protein with a Little Help from REFOLD

artículo científico publicado en 2011

Refolding chromatography with immobilized mini-chaperones

artículo científico publicado en 1997

Scabies mite inactivated serine protease paralogs inhibit the human complement system.

artículo científico publicado en 2009

Serpins in Prokaryotes

Smoothing a rugged protein folding landscape by sequence-based redesign

artículo científico publicado en 2016

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis

artículo científico publicado en 2015

Stability and function: two constraints in the evolution of barstar and other proteins

artículo científico publicado en 1994

Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease

artículo científico publicado en 2020

Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain

artículo científico publicado en 2015

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

artículo científico publicado en 2009

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

artículo científico publicado en 2013

Structural determinants of GAD antigenicity

artículo científico publicado en 2009

Structural mechanisms of inactivation in scabies mite serine protease paralogues

artículo científico publicado en 2009

Structural reconstruction of protein ancestry

artículo científico publicado en 2017

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

artículo científico publicado en 2009

Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases

artículo científico publicado en 2010

Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution

artículo científico publicado en 1994

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target

artículo científico publicado en 2018

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

artículo científico publicado en 2009

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

artículo científico publicado en 2005

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis

artículo científico publicado en 2007

The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore

artículo científico publicado en 2005

The MACPF/CDC family of pore-forming toxins

artículo científico publicado en 2008

The N terminus of the serpin, tengpin, functions to trap the metastable native state

artículo científico publicado en 2007

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger.

artículo científico publicado en 2017

The REFOLD database: a tool for the optimization of protein expression and refolding

artículo científico publicado en 2006

The Rate of PolyQ-Mediated Aggregation Is Dramatically Affected by the Number and Location of Surrounding Domains

artículo científico publicado en 2011

The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome

scientific article published on 19 July 2019

The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions

artículo científico publicado en 2010

The binding of bis-ANS to the isolated GroEL apical domain fragment induces the formation of a folding intermediate with increased hydrophobic surface not observed in tetradecameric GroEL.

artículo científico publicado en 2001

The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A

artículo científico publicado en 2003

The crystal structure of the transthyretin-like protein from Salmonella dublin, a prokaryote 5-hydroxyisourate hydrolase.

artículo científico publicado en 2006

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition

artículo científico publicado en 2004

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

artículo científico publicado en 2005

The matrix refolded

article

The propeptide of human thyroid peroxidase is not required for its cellular, enzymatic or immunological activity

scholarly article by Marlena Godlewska et al published 2013 in Thyroid Research

The role of protein dynamics in the evolution of new enzyme function

artículo científico publicado en 2016

The α-importome of mammalian germ cell maturation provides novel insights for importin biology.

artículo científico publicado en 2014

Thyroid Peroxidase Revisited - What's New?

scientific article published on 11 December 2019

Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity

artículo científico publicado en 2018

Understanding the structural dynamics of TCR-pMHC complex interactions.

artículo científico publicado en 2014

Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments

artículo científico publicado en 2019

X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation

artículo científico publicado en 2006

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin

artículo científico publicado en 2008

X-ray crystal structure of the streptococcal specific phage lysin PlyC. ⬇️

artículo científico publicado en 2012

Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease

artículo científico publicado en 2013

Lista de obras de Ashley Buckle

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily

A colostrum trypsin inhibitor gene expressed in the Cape fur seal mammary gland during lactation

A common fold mediates vertebrate defense and bacterial attack

A structural basis for loop C-sheet polymerization in serpins

A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase

A structural model for GroEL-polypeptide recognition

ARCHER – An Enabler of Research Data Management

ARCHER – e-Research Tools for Research Data Management

An Analysis of the Cross-Reactivity of Autoantibodies to GAD65 and GAD67 in Diabetes ⬇️

An overview of the serpin superfamily

CLIMS: Crystallography Laboratory Information Management System

COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity

Catalytic diversity and cell wall binding repeats in the phage-encoded endolysins

Chiminey: Reliable Computing and Data Management Platform in the Cloud

Circumventing the stability-function trade-off in an engineered FN3 domain

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

Computational Methods for Studying Serpin Conformational Change and Structural Plasticity

Consensus protein design

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans

Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins.

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

Crystallization and preliminary crystallographic studies of a SAM domain at the C-terminus of human p73α

Crystallographic and Molecular Dynamics Analysis of Loop Motions Unmasking the Peptidoglycan-Binding Site in Stator Protein MotB of Flagellar Motor

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Design of highly stable functional GroEL minichaperones.

Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics

Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC

EGM: encapsulated gene-by-gene matching to identify gene orthologs and homologous segments in genomes

Energetic and structural analysis of the role of tryptophan 59 in FKBP12

Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19

Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex

Federated repositories of X-ray diffraction images

From minichaperone to GroEL 1: information on GroEL-polypeptide interactions from crystal packing of minichaperones.

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

High-throughput protein structure determination using grid computing

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics

Interactive visualization tools for the structural biologist

Intrinsic limitations in mainstream methods of identifying network motifs in biology

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors

KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.

Laboratory evolution of protein conformational dynamics.

Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type

MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography

Managing and mining protein crystallization data.

Mapping the pathway and dynamics of bestatin inhibition of the Plasmodium falciparum M1 aminopeptidase, PfA-M1

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1

Membrane proteins of Pseudoalteromonas tunicata during the transition from planktonic to extracellular matrix-adherent state

Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

MrGrid: a portable grid based molecular replacement pipeline

Operation of the Australian Store.Synchrotron for macromolecular crystallography

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase.

PLP-dependent enzymes

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins ⬇️

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif

Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed.

Previously Hidden Dynamics at the TCR-pMHC Interface Revealed

Prodepth: predict residue depth by support vector regression approach from protein sequences only

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium.

REFOLD: an analytical database of protein refolding methods

REFOLDdb: a new and sustainable gateway to experimental protocols for protein refolding

Reactive centre loop dynamics and serpin specificity

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Recombinant protein quality evaluation: proposal for a minimal information standard

Refolding Your Protein with a Little Help from REFOLD

Refolding chromatography with immobilized mini-chaperones

Scabies mite inactivated serine protease paralogs inhibit the human complement system.

Serpins in Prokaryotes