Lista de obras - John H. Dawson - Dominio Público Uruguay

A heme-based redox sensor in the methanogenic archaeon Methanosarcina acetivorans

artículo científico publicado en 2013

A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid

artículo científico publicado en 2011

A study of the K(+)-site mutant of ascorbate peroxidase: mutations of protein residues on the proximal side of the heme cause changes in iron ligation on the distal side

artículo científico publicado en 1999

Alkylamine-ligated H93G myoglobin cavity mutant: a model system for endogenous lysine and terminal amine ligation in heme proteins such as nitrite reductase and cytochrome f.

artículo científico publicado en 2011

Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using “Peroxidase-like” Myoglobin Mutants and “Myoglobin-like” DHP Mutants ⬇️

artículo científico publicado el 30 de agosto de 2011

Amphitrite ornata dehaloperoxidase: enhanced activity for the catalytically active globin using MCPBA.

artículo científico publicado en 2004

Assignment of the heme axial ligand(s) for the ferric myoglobin (H93G) and heme oxygenase (H25A) cavity mutants as oxygen donors using magnetic circular dichroism

artículo científico publicado en 1999

C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols

artículo científico publicado en 2006

Caldariomyces fumago chloroperoxidase catalyzes the oxidative dehalogenation of chlorophenols by a mechanism involving two one-electron steps

artículo científico publicado en 2007

Characterization of SiaA, a streptococcal heme-binding protein associated with a heme ABC transport system

artículo científico

Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: evidence for tyrosinate ligation to the ferric enzyme heme iron

artículo científico publicado en 2001

Characterization of the periplasmic heme-binding protein shut from the heme uptake system of Shigella dysenteriae

artículo científico publicado en 2005

Characterization of the spleen green hemeprotein with magnetic and natural circular dichroism spectroscopy: positive evidence for a myeloperoxidase-type active site

scientific article published on 01 September 1986

Contributions from the 13th International Conference on Bioinorganic Chemistry. Preface

artículo científico publicado en 2008

Coordination modes of tyrosinate-ligated catalase-type heme enzymes: magnetic circular dichroism studies of Plexaura homomalla allene oxide synthase, Mycobacterium avium ssp. paratuberculosis protein-2744c, and bovine liver catalase in their ferric

scientific article published in 2011

Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant

artículo científico publicado en 2005

Design of a five-coordinate heme protein maquette: a spectroscopic model of deoxymyoglobin

artículo científico publicado en 2004

Direct observation of a novel perturbed oxyferrous catalytic intermediate during reduced putidaredoxin-initiated turnover of cytochrome P-450-CAM: probing the effector role of putidaredoxin in catalysis

artículo científico publicado en 2005

EPR and ENDOR characterization of intermediates in the cryoreduced oxy-nitric oxide synthase heme domain with bound L-arginine or N(G)-hydroxyarginine

artículo científico publicado en 2002

EPR and ENDOR studies of cryoreduced compounds II of peroxidases and myoglobin. Proton-coupled electron transfer and protonation status of ferryl hemes

artículo científico publicado en 2008

Effects of cyanogen bromide modification of the distal histidine on the spectroscopic and ligand binding properties of myoglobin: magnetic circular dichroism spectroscopy as a probe of distal water ligation in ferric high-spin histidine-bound heme p

artículo científico publicado en 1991

Effects of urea and acetic acid on the heme axial ligation structure of ferric myoglobin at very acidic pH.

artículo científico publicado en 2009

Electrochemistry of unfolded cytochrome c in neutral and acidic urea solutions

artículo científico publicado en 2005

Electron paramagnetic resonance and electron-nuclear double resonance studies of the reactions of cryogenerated hydroperoxoferric-hemoprotein intermediates

artículo científico publicado en 2014

Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron

artículo científico publicado en 1991

Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation

artículo científico publicado en 1999

EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme

artículo científico publicado en 2004

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

artículo científico publicado en 2003

Essential thiol requirement to restore pterin- or substrate-binding capability and to regenerate native enzyme-type high-spin heme spectra in the Escherichia coli-expressed tetrahydrobiopterin-free oxygenase domain of neuronal nitric oxide synthase

article

Evaluation of electron-withdrawing group effects on heme binding in designed proteins: implications for heme a in cytochrome c oxidase

artículo científico publicado en 2006

Evidence of the direct involvement of the substrate TCP radical in functional switching from oxyferrous O2 carrier to ferric peroxidase in the dual-function hemoglobin/dehaloperoxidase from Amphitrite ornata

artículo científico publicado en 2014

Extensive studies of the heme coordination structure of indoleamine 2,3-dioxygenase and of tryptophan binding with magnetic and natural circular dichroism and electron paramagnetic resonance spectroscopy

artículo científico publicado en 1984

Functional switching of Amphitrite ornata dehaloperoxidase from O2-binding globin to peroxidase enzyme facilitated by halophenol substrate and H2O2.

artículo científico publicado en 2010

Heme binding to the Mammalian circadian clock protein period 2 is nonspecific

artículo científico publicado en 2010

Histidine-tailed microperoxidase-10: a pH-dependent ligand switch

artículo científico publicado en 1998

Horse heart myoglobin catalyzes the H2O2-dependent oxidative dehalogenation of chlorophenols to DNA-binding radicals and quinones

scientific article published on 04 August 2007

Hydroperoxoferric heme intermediate as a second electrophilic oxidant in cytochrome P450-catalyzed reactions.

artículo científico publicado en 2004

Investigations of heme ligation and ligand switching in cytochromes p450 and p420.

artículo científico publicado en 2013

Ligation of the iron in the heme-heme oxygenase complex: X-ray absorption, electronic absorption and magnetic circular dichroism studies

artículo científico publicado en 1996

Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy

artículo científico publicado en 2008

Low-temperature stabilization and spectroscopic characterization of the dioxygen complex of the ferrous neuronal nitric oxide synthase oxygenase domain

artículo científico publicado en 1999

Magnetic circular dichroism of ferrous carbonyl adducts of cytochromes P-450 and P-420 and their synthetic models: further evidence for mercaptide as the fifth ligand to iron ⬇️

artículo científico publicado el 1 de enero de 1976

Magnetic circular dichroism spectroscopic characterization of the NOS-like protein from Geobacillus stearothermophilus (gsNOS).

artículo científico publicado en 2010

Magnetic circular dichroism spectroscopy as a probe of axial heme ligand replacement in semisynthetic mutants of cytochrome c.

artículo científico publicado en 1991

Magnetic circular dichroism studies XXXIV. Improved instrumentation for MCD measurements

scientific article published on 01 May 1975

Magnetic circular dichroism studies XXXV. A comparison of cytochromes P-450 and P-448.

artículo científico publicado en 1974

Magnetic circular dichroism studies of the active site structure of hemoprotein H-450: comparison to cytochrome P-450 and sensitivity to pH effects

scientific article published on 01 December 1989

Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant

artículo científico publicado en 2010

Mono- and bis-phosphine-ligated H93G myoglobin: spectral models for ferrous-phosphine and ferrous-CO cytochrome P450.

artículo científico publicado en 2013

Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction

artículo científico publicado en 2003

Notomastus lobatus chloroperoxidase and Amphitrite ornata dehaloperoxidase both contain histidine as their proximal heme iron ligand

scientific article published on 01 February 1997

On the use of iron octa-alkylporphyrins as models for protoporphyrin IX-containing heme systems in studies employing magnetic circular dichroism spectroscopy

artículo científico publicado en 1992

Oxoiron(IV) in chloroperoxidase compound II is basic: implications for P450 chemistry

artículo científico publicado en 2004

Oxygenated cytochrome P-450cam: evidence against axial histidine ligation of iron

artículo científico publicado en 1978

Preparation and initial characterization of the compound I, II, and III states of iron methylchlorin-reconstituted horseradish peroxidase and myoglobin: models for key intermediates in iron chlorin enzymes

artículo científico publicado en 2000

Probing the heme iron coordination structure of alkaline chloroperoxidase

artículo científico publicado en 1996

Probing the oxyferrous and catalytically active ferryl states of Amphitrite ornata dehaloperoxidase by cryoreduction and EPR/ENDOR spectroscopy. Detection of compound I.

artículo científico publicado en 2010

Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical

artículo científico publicado en 2006

Rapid kinetics investigations of peracid oxidation of ferric cytochrome P450cam: nature and possible function of compound ES.

artículo científico

Reaction of ferric cytochrome P450cam with peracids: kinetic characterization of intermediates on the reaction pathway

artículo científico publicado en 2005

Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins.

artículo científico publicado en 2014

Replacement of the axial histidine heme ligand with cysteine in nitrophorin 1: spectroscopic and crystallographic characterization.

artículo científico publicado en 2008

Replacement of tyrosine residues by phenylalanine in cytochrome P450cam alters the formation of Cpd II-like species in reactions with artificial oxidants

artículo científico publicado en 2008

Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism

artículo científico publicado en 2002

Single turnover studies of oxidative halophenol dehalogenation by horseradish peroxidase reveal a mechanism involving two consecutive one electron steps: toward a functional halophenol bioremediation catalyst

scientific article published on 25 September 2012

Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide syntha

artículo científico publicado en 2003

Spectroscopic characterization of the ferric states of Amphitrite ornata dehaloperoxidase and Notomastus lobatus chloroperoxidase: His-ligated peroxidases with globin-like proximal and distal properties

artículo científico publicado en 2006

Spectroscopic investigations of intermediates in the reaction of cytochrome P450(BM3)-F87G with surrogate oxygen atom donors

artículo científico publicado en 2006

Stabilization and spectroscopic characterization of the dioxygen complex of wild-type cytochrome P4502B4 (CYP2B4) and its distal side E301Q, T302A and proximal side F429H mutants at subzero temperatures

artículo científico publicado en 2010

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

artículo científico publicado en 2005

Subzero-temperature stabilization and spectroscopic characterization of homogeneous oxyferrous complexes of the cytochrome P450 BM3 (CYP102) oxygenase domain and holoenzyme

artículo científico publicado en 2005

The H93G Myoglobin Cavity Mutant as a Versatile Scaffold for Modeling Heme Iron Coordination Structures in Protein Active Sites and Their Characterization with Magnetic Circular Dichroism Spectroscopy

scientific article published on April 2011

The H93G myoglobin cavity mutant as a versatile template for modeling heme proteins: ferrous, ferric, and ferryl mixed-ligand complexes with imidazole in the cavity

scientific article published on 01 December 2000

The active site structure of E. coli HPII catalase. Evidence favoring coordination of a tyrosinate proximal ligand to the chlorin iron.

artículo científico publicado en 1991

The ferric-hydroperoxo complex of chloroperoxidase

artículo científico publicado en 2007

The influence of oxygen donor ligation on the spectroscopic properties of ferric cytochrome P-450: ester, ether and ketone co-ordination to the haem iron

scientific article published on 01 January 1984

The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM.

artículo científico publicado en 2005

The mechanism of oxidative halophenol dehalogenation by Amphitrite ornata dehaloperoxidase is initiated by H2O2 binding and involves two consecutive one-electron steps: role of ferryl intermediates

artículo científico publicado en 2009

Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-CAM. Direct observation of an intermolecular isotope effect for substrate C-H activation

artículo científico publicado en 1995

Lista de obras de John H. Dawson

A heme-based redox sensor in the methanogenic archaeon Methanosarcina acetivorans

A novel intermediate in the reaction of seleno CYP119 with m-chloroperbenzoic acid

A study of the K(+)-site mutant of ascorbate peroxidase: mutations of protein residues on the proximal side of the heme cause changes in iron ligation on the distal side

Alkylamine-ligated H93G myoglobin cavity mutant: a model system for endogenous lysine and terminal amine ligation in heme proteins such as nitrite reductase and cytochrome f.

Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using “Peroxidase-like” Myoglobin Mutants and “Myoglobin-like” DHP Mutants ⬇️

Amphitrite ornata dehaloperoxidase: enhanced activity for the catalytically active globin using MCPBA.

Assignment of the heme axial ligand(s) for the ferric myoglobin (H93G) and heme oxygenase (H25A) cavity mutants as oxygen donors using magnetic circular dichroism

C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols

Caldariomyces fumago chloroperoxidase catalyzes the oxidative dehalogenation of chlorophenols by a mechanism involving two one-electron steps

Characterization of SiaA, a streptococcal heme-binding protein associated with a heme ABC transport system

Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: evidence for tyrosinate ligation to the ferric enzyme heme iron

Characterization of the periplasmic heme-binding protein shut from the heme uptake system of Shigella dysenteriae

Characterization of the spleen green hemeprotein with magnetic and natural circular dichroism spectroscopy: positive evidence for a myeloperoxidase-type active site

Contributions from the 13th International Conference on Bioinorganic Chemistry. Preface

Coordination modes of tyrosinate-ligated catalase-type heme enzymes: magnetic circular dichroism studies of Plexaura homomalla allene oxide synthase, Mycobacterium avium ssp. paratuberculosis protein-2744c, and bovine liver catalase in their ferric

Cryoreduction EPR and 13C, 19F ENDOR study of substrate-bound substates and solvent kinetic isotope effects in the catalytic cycle of cytochrome P450cam and its T252A mutant

Design of a five-coordinate heme protein maquette: a spectroscopic model of deoxymyoglobin

Direct observation of a novel perturbed oxyferrous catalytic intermediate during reduced putidaredoxin-initiated turnover of cytochrome P-450-CAM: probing the effector role of putidaredoxin in catalysis

EPR and ENDOR characterization of intermediates in the cryoreduced oxy-nitric oxide synthase heme domain with bound L-arginine or N(G)-hydroxyarginine

EPR and ENDOR studies of cryoreduced compounds II of peroxidases and myoglobin. Proton-coupled electron transfer and protonation status of ferryl hemes

Effects of cyanogen bromide modification of the distal histidine on the spectroscopic and ligand binding properties of myoglobin: magnetic circular dichroism spectroscopy as a probe of distal water ligation in ferric high-spin histidine-bound heme p

Effects of urea and acetic acid on the heme axial ligation structure of ferric myoglobin at very acidic pH.

Electrochemistry of unfolded cytochrome c in neutral and acidic urea solutions

Electron paramagnetic resonance and electron-nuclear double resonance studies of the reactions of cryogenerated hydroperoxoferric-hemoprotein intermediates

Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron

Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation

EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

Essential thiol requirement to restore pterin- or substrate-binding capability and to regenerate native enzyme-type high-spin heme spectra in the Escherichia coli-expressed tetrahydrobiopterin-free oxygenase domain of neuronal nitric oxide synthase

Evaluation of electron-withdrawing group effects on heme binding in designed proteins: implications for heme a in cytochrome c oxidase

Evidence of the direct involvement of the substrate TCP radical in functional switching from oxyferrous O2 carrier to ferric peroxidase in the dual-function hemoglobin/dehaloperoxidase from Amphitrite ornata

Extensive studies of the heme coordination structure of indoleamine 2,3-dioxygenase and of tryptophan binding with magnetic and natural circular dichroism and electron paramagnetic resonance spectroscopy

Functional switching of Amphitrite ornata dehaloperoxidase from O2-binding globin to peroxidase enzyme facilitated by halophenol substrate and H2O2.

Heme binding to the Mammalian circadian clock protein period 2 is nonspecific

Histidine-tailed microperoxidase-10: a pH-dependent ligand switch

Horse heart myoglobin catalyzes the H2O2-dependent oxidative dehalogenation of chlorophenols to DNA-binding radicals and quinones

Hydroperoxoferric heme intermediate as a second electrophilic oxidant in cytochrome P450-catalyzed reactions.

Investigations of heme ligation and ligand switching in cytochromes p450 and p420.

Ligation of the iron in the heme-heme oxygenase complex: X-ray absorption, electronic absorption and magnetic circular dichroism studies

Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy

Low-temperature stabilization and spectroscopic characterization of the dioxygen complex of the ferrous neuronal nitric oxide synthase oxygenase domain

Magnetic circular dichroism of ferrous carbonyl adducts of cytochromes P-450 and P-420 and their synthetic models: further evidence for mercaptide as the fifth ligand to iron ⬇️

Magnetic circular dichroism spectroscopic characterization of the NOS-like protein from Geobacillus stearothermophilus (gsNOS).

Magnetic circular dichroism spectroscopy as a probe of axial heme ligand replacement in semisynthetic mutants of cytochrome c.

Magnetic circular dichroism studies XXXIV. Improved instrumentation for MCD measurements

Magnetic circular dichroism studies XXXV. A comparison of cytochromes P-450 and P-448.

Magnetic circular dichroism studies of the active site structure of hemoprotein H-450: comparison to cytochrome P-450 and sensitivity to pH effects

Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant

Mono- and bis-phosphine-ligated H93G myoglobin: spectral models for ferrous-phosphine and ferrous-CO cytochrome P450.

Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction

Notomastus lobatus chloroperoxidase and Amphitrite ornata dehaloperoxidase both contain histidine as their proximal heme iron ligand

On the use of iron octa-alkylporphyrins as models for protoporphyrin IX-containing heme systems in studies employing magnetic circular dichroism spectroscopy

Oxoiron(IV) in chloroperoxidase compound II is basic: implications for P450 chemistry

Oxygenated cytochrome P-450cam: evidence against axial histidine ligation of iron

Preparation and initial characterization of the compound I, II, and III states of iron methylchlorin-reconstituted horseradish peroxidase and myoglobin: models for key intermediates in iron chlorin enzymes

Probing the heme iron coordination structure of alkaline chloroperoxidase

Probing the oxyferrous and catalytically active ferryl states of Amphitrite ornata dehaloperoxidase by cryoreduction and EPR/ENDOR spectroscopy. Detection of compound I.

Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical

Rapid kinetics investigations of peracid oxidation of ferric cytochrome P450cam: nature and possible function of compound ES.

Reaction of ferric cytochrome P450cam with peracids: kinetic characterization of intermediates on the reaction pathway

Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins.

Replacement of the axial histidine heme ligand with cysteine in nitrophorin 1: spectroscopic and crystallographic characterization.

Replacement of tyrosine residues by phenylalanine in cytochrome P450cam alters the formation of Cpd II-like species in reactions with artificial oxidants

Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism

Single turnover studies of oxidative halophenol dehalogenation by horseradish peroxidase reveal a mechanism involving two consecutive one electron steps: toward a functional halophenol bioremediation catalyst

Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide syntha

Spectroscopic characterization of the ferric states of Amphitrite ornata dehaloperoxidase and Notomastus lobatus chloroperoxidase: His-ligated peroxidases with globin-like proximal and distal properties

Spectroscopic investigations of intermediates in the reaction of cytochrome P450(BM3)-F87G with surrogate oxygen atom donors

Stabilization and spectroscopic characterization of the dioxygen complex of wild-type cytochrome P4502B4 (CYP2B4) and its distal side E301Q, T302A and proximal side F429H mutants at subzero temperatures

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

Subzero-temperature stabilization and spectroscopic characterization of homogeneous oxyferrous complexes of the cytochrome P450 BM3 (CYP102) oxygenase domain and holoenzyme

The H93G Myoglobin Cavity Mutant as a Versatile Scaffold for Modeling Heme Iron Coordination Structures in Protein Active Sites and Their Characterization with Magnetic Circular Dichroism Spectroscopy

The H93G myoglobin cavity mutant as a versatile template for modeling heme proteins: ferrous, ferric, and ferryl mixed-ligand complexes with imidazole in the cavity

The active site structure of E. coli HPII catalase. Evidence favoring coordination of a tyrosinate proximal ligand to the chlorin iron.

The ferric-hydroperoxo complex of chloroperoxidase

The influence of oxygen donor ligation on the spectroscopic properties of ferric cytochrome P-450: ester, ether and ketone co-ordination to the haem iron

The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM.

The mechanism of oxidative halophenol dehalogenation by Amphitrite ornata dehaloperoxidase is initiated by H2O2 binding and involves two consecutive one-electron steps: role of ferryl intermediates

Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-CAM. Direct observation of an intermolecular isotope effect for substrate C-H activation