Lista de obras - Imre Kovesdi - Dominio Público Uruguay

"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype

article

A factor discriminating between the wild-type and a mutant polyomavirus enhancer

artículo científico

Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo

artículo científico publicado en 1997

Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity

artículo científico publicado en 2004

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

artículo científico publicado en 2000

Adenoviral producer cells

artículo científico

Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis

artículo científico publicado en 1997

Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws

artículo científico publicado en 1999

Adenoviral vectors for gene transfer

artículo científico publicado en 1997

Adenovirus as a gene therapy vector for hematopoietic cells.

artículo científico publicado en 2000

Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression

artículo científico publicado en 1997

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

artículo científico publicado en 1996

Adenovirus type 9 fiber knob binds to the coxsackie B virus-adenovirus receptor (CAR) with lower affinity than fiber knobs of other CAR-binding adenovirus serotypes

artículo científico publicado en 2001

Adenovirus vectors targeting alphaV integrin or heparan sulfate receptors display different distribution of transgene activity after intramuscular injection.

artículo científico publicado en 2004

Adenovirus-mediated E2F-1 gene transfer in nonsmall-cell lung cancer induces cell growth arrest and apoptosis.

artículo científico publicado en 2002

Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia

artículo científico publicado en 2000

Adenovirus-mediated gene transfer of human inducible nitric oxide synthase in porcine vein grafts inhibits intimal hyperplasia

article

Adenovirus-mediated increase of HNF-3 levels stimulates expression of transthyretin and sonic hedgehog, which is associated with F9 cell differentiation toward the visceral endoderm lineage

artículo científico publicado en 2001

Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis

artículo científico publicado en 1998

Adenovirus-mediated transduction of intestinal cells in vivo

artículo científico publicado en 1998

Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium.

artículo científico publicado en 1999

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

article

CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.

artículo científico publicado en 1999

Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man

artículo científico publicado en 1995

Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2

artículo científico publicado en 1993

Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype

scientific article published on 01 January 1997

Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins

artículo científico publicado en 1991

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy.

artículo científico publicado en 2000

Comparative analysis of adenovirus fiber-cell interaction: adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment

artículo científico publicado en 1996

Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base.

artículo científico publicado en 1999

Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector

artículo científico publicado en 2012

Development of an Ad7 cosmid system and generation of an Ad7deltaE1deltaE3HIV(MN) env/rev recombinant virus

artículo científico publicado en 2003

Developmental control of a promoter-specific factor that is also regulated by the E1A gene product

artículo científico publicado en 1987

Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees

article

E1A transcription induction: enhanced binding of a factor to upstream promoter sequences

artículo científico publicado en 1986

Effective multiple oral administration of reverse genetics engineered infectious bursal disease virus in mice in the presence of neutralizing antibodies

artículo científico publicado en 2015

Effective repeat administration with adenovirus vectors to the muscle

artículo científico publicado en 2000

Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival.

artículo científico publicado en 2001

Efficient adenoviral gene transfer to kidney cortical vasculature utilizing a fiber modified vector

artículo científico publicado en 1999

Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo

artículo científico publicado en 1998

Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models

artículo científico publicado en 2000

Endothelial nitric oxide synthase protects aortic allografts from the development of transplant arteriosclerosis

artículo científico publicado en 2000

Enhanced liver uptake of opsonized red blood cells after in vivo transfer of FcgammaRIIA cDNA to the liver

artículo científico publicado en 1999

Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity

artículo científico publicado en 2006

Ex vivo adenovirus mediated gene transfection of human conjunctival epithelium

artículo científico publicado en 2001

Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries

artículo científico publicado en 2002

Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver ⬇️

artículo científico publicado el 1 de octubre de 1997

Expression of the HBNF (heparin-binding neurite-promoting factor) gene in the brain of fetal, neonatal and adult rat: an in situ hybridization study

artículo científico publicado el 18 de diciembre de 1992

Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle

artículo científico publicado en 1999

Gene therapy for collateral vessel development.

artículo científico publicado en 1997

Gene therapy with angiogenic factors: a new potential approach to the treatment of ischemic diseases

artículo científico publicado en 1997

Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension

artículo científico publicado en 2003

Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging

artículo científico publicado en 2011

Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant

artículo científico publicado en 1993

HBNF and MK, members of a novel gene family of heparin-binding proteins with potential roles in embryogenesis and brain function.

artículo científico publicado en 1991

Heparin-binding neurotrophic factor (HBNF) and MK, members of a new family of homologous, developmentally regulated proteins ⬇️

artículo científico publicado el 30 de octubre de 1990

Identification of a cellular transcription factor involved in E1A trans-activation

artículo científico publicado en 1986

Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae

artículo científico publicado en 1999

Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein

artículo científico publicado en 2000

Improved production of adenovirus vectors expressing apoptotic transgenes

artículo científico publicado en 2000

In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery

artículo científico publicado en 2003

In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits

artículo científico publicado en 2003

Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein.

artículo científico publicado en 1999

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

artículo científico publicado en 1997

Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121).

artículo científico publicado en 2004

Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate

artículo científico publicado en 2000

Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis.

artículo científico publicado en 1997

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12.

artículo científico publicado en 1999

Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization

artículo científico publicado en 2001

Inhibitory effect of recombinant iNOS gene expression on vasomotor function of canine basilar artery

artículo científico publicado en 2002

Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis

artículo científico publicado en 1998

Isolation from bovine brain and structural characterization of HBNF, a heparin-binding neurotrophic factor

artículo científico publicado en 1991

Local adenoviral-mediated inducible nitric oxide synthase gene transfer inhibits neointimal formation in the porcine coronary stented model

article

Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer

artículo científico publicado en 2004

Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses

artículo científico publicado en 2004

Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression

artículo científico publicado en 2002

Modifications of the fiber in adenovirus vectors increase tropism for malignant glioma models

artículo científico publicado en 2000

Muscle stem cells can act as antigen-presenting cells: implication for gene therapy

artículo científico publicado en 2004

Nitric oxide prevents p21 degradation with the ubiquitin-proteasome pathway in vascular smooth muscle cells

artículo científico publicado en 2000

Optimization of ex vivo inducible nitric oxide synthase gene transfer to vein grafts

artículo científico publicado en 1999

Optimizing cardiovascular gene therapy: increased vascular gene transfer with modified adenoviral vectors

artículo científico publicado en 2000

Periocular gene transfer of sFlt-1 suppresses ocular neovascularization and vascular endothelial growth factor-induced breakdown of the blood-retinal barrier

artículo científico publicado en 2003

Polylysine modification of adenoviral fiber protein enhances muscle cell transduction

artículo científico publicado en 1999

Potentiation of nitric oxide-induced apoptosis in p53-/- vascular smooth muscle cells

artículo científico publicado en 2002

Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex

artículo científico publicado en 1987

Promoters influence the kinetics of transgene expression following adenovector gene delivery

artículo científico publicado en 2008

Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.

artículo científico publicado en 2005

Protection from reoxygenation injury by inhibition of rac1.

scientific article published on May 1998

Quantitative assessment of actin transcript number in eggs, embryos, and tube feet of the sea star Pisaster ochraceus.

artículo científico publicado en 1985

Rapid construction of adenoviral vectors by lambda phage genetics

artículo científico publicado en 2002

Rat sponge implant model: a new system for evaluating angiogenic gene transfer.

artículo científico publicado en 2000

Recombinant infectious bursal disease virus carrying hepatitis C virus epitopes

artículo científico publicado en 2010

Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

artículo científico publicado en 2001

Refolding and characterization of human recombinant heparin-binding neurite-promoting factor

artículo científico publicado en 1994

Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor

artículo científico publicado en 1998

Regulation of tissue factor expression in smooth muscle cells with nitric oxide

artículo científico publicado en 2003

Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer

artículo científico publicado en 1998

Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen.

artículo científico publicado en 2000

Sequence complexity in the maternal RNA of the starfish Pisaster ochraceus (Brandt)

scientific article published on 01 January 1982

Structure of the gene coding for the human retinoic acid-inducible factor, MK

artículo científico publicado en 1993

Structure/activity relationships in basic FGF

scientific article published on 01 January 1991

Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies

artículo científico publicado en 1996

Targeted adenovirus-mediated gene delivery to T cells via CD3.

artículo científico publicado en 1997

Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectin

artículo científico publicado en 1999

Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammation

artículo científico publicado en 1997

Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs.

artículo científico publicado en 1995

The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities

scientific article published on 01 December 1991

The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F

artículo científico publicado en 1998

The role of receptors in the maturation-dependent adenoviral transduction of myofibers

artículo científico publicado en 2001

Transactivation by the adenovirus E1A gene.

artículo científico publicado en 1988

Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells.

artículo científico publicado en 1999

VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases

artículo científico publicado en 1999

Vascular permeability effect of adenovirus-mediated vascular endothelial growth factor gene transfer to the rabbit and rat skeletal muscle

artículo científico publicado en 1999

Lista de obras de Imre Kovesdi

"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype

A factor discriminating between the wild-type and a mutant polyomavirus enhancer

Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo

Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

Adenoviral producer cells

Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis

Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws

Adenoviral vectors for gene transfer

Adenovirus as a gene therapy vector for hematopoietic cells.

Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

Adenovirus type 9 fiber knob binds to the coxsackie B virus-adenovirus receptor (CAR) with lower affinity than fiber knobs of other CAR-binding adenovirus serotypes

Adenovirus vectors targeting alphaV integrin or heparan sulfate receptors display different distribution of transgene activity after intramuscular injection.

Adenovirus-mediated E2F-1 gene transfer in nonsmall-cell lung cancer induces cell growth arrest and apoptosis.

Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia

Adenovirus-mediated gene transfer of human inducible nitric oxide synthase in porcine vein grafts inhibits intimal hyperplasia

Adenovirus-mediated increase of HNF-3 levels stimulates expression of transthyretin and sonic hedgehog, which is associated with F9 cell differentiation toward the visceral endoderm lineage

Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis

Adenovirus-mediated transduction of intestinal cells in vivo

Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium.

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.

Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man

Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2

Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype

Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy.

Comparative analysis of adenovirus fiber-cell interaction: adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment

Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base.

Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector

Development of an Ad7 cosmid system and generation of an Ad7deltaE1deltaE3HIV(MN) env/rev recombinant virus

Developmental control of a promoter-specific factor that is also regulated by the E1A gene product

Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees

E1A transcription induction: enhanced binding of a factor to upstream promoter sequences

Effective multiple oral administration of reverse genetics engineered infectious bursal disease virus in mice in the presence of neutralizing antibodies

Effective repeat administration with adenovirus vectors to the muscle

Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival.

Efficient adenoviral gene transfer to kidney cortical vasculature utilizing a fiber modified vector

Efficient inhibition of intimal hyperplasia by adenovirus-mediated inducible nitric oxide synthase gene transfer to rats and pigs in vivo

Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models

Endothelial nitric oxide synthase protects aortic allografts from the development of transplant arteriosclerosis

Enhanced liver uptake of opsonized red blood cells after in vivo transfer of FcgammaRIIA cDNA to the liver

Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity

Ex vivo adenovirus mediated gene transfection of human conjunctival epithelium

Expression and function of recombinant S1179D endothelial nitric oxide synthase in canine cerebral arteries

Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver ⬇️

Expression of the HBNF (heparin-binding neurite-promoting factor) gene in the brain of fetal, neonatal and adult rat: an in situ hybridization study

Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle

Gene therapy for collateral vessel development.

Gene therapy with angiogenic factors: a new potential approach to the treatment of ischemic diseases

Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension

Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging

Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant

HBNF and MK, members of a novel gene family of heparin-binding proteins with potential roles in embryogenesis and brain function.

Heparin-binding neurotrophic factor (HBNF) and MK, members of a new family of homologous, developmentally regulated proteins ⬇️

Identification of a cellular transcription factor involved in E1A trans-activation

Identification of a conserved receptor-binding site on the fiber proteins of CAR-recognizing adenoviridae

Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein

Improved production of adenovirus vectors expressing apoptotic transgenes

In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery

In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits

Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein.

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121).

Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate

Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis.

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12.

Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization

Inhibitory effect of recombinant iNOS gene expression on vasomotor function of canine basilar artery

Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis

Isolation from bovine brain and structural characterization of HBNF, a heparin-binding neurotrophic factor

Local adenoviral-mediated inducible nitric oxide synthase gene transfer inhibits neointimal formation in the porcine coronary stented model

Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer

Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses

Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression

Modifications of the fiber in adenovirus vectors increase tropism for malignant glioma models

Muscle stem cells can act as antigen-presenting cells: implication for gene therapy

Nitric oxide prevents p21 degradation with the ubiquitin-proteasome pathway in vascular smooth muscle cells