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Lista de obras de Andras Perl

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

artículo científico publicado en 2009

Activation of the Mechanistic Target of Rapamycin in SLE: Explosion of Evidence in the Last Five Years

artículo científico publicado en 2016

Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)

scientific journal article

Advances in the o-phthalaldehyde derivatizations. Comeback to the o-phthalaldehyde-ethanethiol reagent.

artículo científico publicado en 2007

Analysis of amino acids and biogenic amines in biological tissues as their o-phthalaldehyde/ethanethiol/fluorenylmethyl chloroformate derivatives by high-performance liquid chromatography. A deproteinization study

artículo científico publicado en 2006

Antibody reactivity to the HRES-1 endogenous retroviral element identifies a subset of patients with systemic lupus erythematosus and overlap syndromes. Correlation with antinuclear antibodies and HLA class II alleles

artículo científico publicado en 1995

Antiphospholipid antibody syndrome associated with primary angiitis of the central nervous system: report of two biopsy proven cases

artículo científico publicado en 2006

Apoptosis and mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus

artículo científico publicado en 2004

Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus

artículo científico publicado en 2008

Attention deficit and hyperactivity disorder scores are elevated and respond to N-acetylcysteine treatment in patients with systemic lupus erythematosus

artículo científico publicado en 2013

CCL genes in multiple sclerosis and systemic lupus erythematosus

artículo científico publicado en 2008

CD8+ T cell-mediated HLA-A*0201-restricted cytotoxicity to transaldolase peptide 168-176 in patients with multiple sclerosis

artículo científico publicado en 2005

Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus.

artículo científico publicado en 2010

Characterization of the effector cells in Con A-induced cytotoxicity against HEp 2 tumour targets

artículo científico publicado en 1983

Cleavage of transaldolase by granzyme B causes the loss of enzymatic activity with retention of antigenicity for multiple sclerosis patients

artículo científico publicado en 2010

Clonal B cell expansions in patients with essential mixed cryoglobulinaemia

artículo científico publicado en 1989

Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence.

artículo científico publicado en 1994

Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis

scientific article published on March 1997

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin

artículo científico publicado en 2015

Contrasting effects of RNA and protein synthesis blocking on natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

artículo científico publicado en 1985

Deletion of Ser-171 causes inactivation, proteasome-mediated degradation and complete deficiency of human transaldolase

artículo científico publicado en 2004

Depressed effector activity of OKT4+ and OKT8+ T cell subsets in lectin-dependent cell-mediated cytotoxicity to HEP-2 cells in patients with systemic lupus erythematosus

artículo científico publicado el 1 de octubre de 1984

Depressed lectin-dependent and enhanced antibody-dependent cell-mediated cytotoxicity in patients with stage I cancer of the larynx

scientific article published on 01 January 1986

Depressed lectin-dependent cell-mediated cytotoxicity against HEp-2 cells in patients with metastasizing solid tumour

artículo científico publicado en 1985

Depressed lectin-dependent cell-mediated cytotoxicity against adherent HEP-2 cells in patients with carcinoma of the uterine cervix

artículo científico publicado en 1983

Depressed natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells in patients with systemic lupus erythematosus

scientific article published on 01 January 1982

Detection and cloning of new HTLV-related endogenous sequences in man

artículo científico publicado en 1989

Detection and mapping of polymorphic KpnI alleles in the human T-cell receptor constant beta-2 locus

artículo científico publicado en 1989

Detection of lupus anticoagulant and successful anticoagulation in familial Sneddon syndrome

artículo científico publicado en 2010

Differential regulation of hydrogen peroxide and Fas-dependent apoptosis pathways by dehydroascorbate, the oxidized form of vitamin C.

artículo científico publicado en 2002

Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus

artículo científico publicado en 2011

Effect of (+)cyanidanol-3 on cellular immune reactions and on superoxide dismutase activity in vitro

artículo científico publicado en 1987

Effect of Fc receptor blocking on human natural and lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

artículo científico publicado en 1983

Effect of histamine-receptor blocking on human natural and lectin-dependent cell-mediated cytotoxicity against adherent HEP-2 cells.

artículo científico publicado en 1985

Effector activity of OKT4+ and OKT8+ T-cell subsets in lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

scientific article published on 01 March 1984

Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling

artículo científico publicado en 1999

Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome.

artículo científico publicado en 2009

Endogenous retroviral pathogenesis in lupus

scientific article published on September 2010

Endothelial nitric oxide synthase reduces crescentic and necrotic glomerular lesions, reactive oxygen production, and MCP1 production in murine lupus nephritis

artículo científico publicado en 2013

Evaluation of autoimmunity to transaldolase in multiple sclerosis

artículo científico publicado en 2004

Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin

artículo científico publicado en 2007

Genetic and metabolic control of the mitochondrial transmembrane potential and reactive oxygen intermediate production in HIV disease.

artículo científico publicado en 2000

Glutathione Levels and Sensitivity to Apoptosis Are Regulated by Changes in Transaldolase Expression

artículo científico publicado en 1996

HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy

artículo científico publicado en 2014

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.

artículo científico publicado en 2013

Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus

scientific article published on 01 February 2008

Human T-cell leukemia virus type I or a related retrovirus in patients with mycosis fungoides/Sézary syndrome and Kaposi's sarcoma

artículo científico publicado el 15 de agosto de 1992

Human T-cell lymphotropic virus (HTLV)-related endogenous sequence, HRES-1, encodes a 28-kDa protein: a possible autoantigen for HTLV-I gag-reactive autoantibodies

artículo científico publicado el 1 de marzo de 1992

Human lectin-dependent T cell-mediated cytotoxicity against Hep-2 cells

scientific article published on 01 January 1983

Human transaldolase and cross-reactive viral epitopes identified by autoantibodies of multiple sclerosis patients.

artículo científico publicado en 1999

Human transaldolase-associated repetitive elements are transcribed by RNA polymerase III.

artículo científico publicado en 2000

Hypoglycaemia after initiation of treatment with etanercept in a patient with type 2 diabetes mellitus

artículo científico publicado en 2007

Identification of mitochondrial genome concatemers in AIDS-associated lymphomas and lymphoid cell lines

artículo científico publicado en 2009

Immunofluorescence microscopy is superior to fluorescent beads for detection of antinuclear antibody reactivity in systemic lupus erythematosus patients

artículo científico publicado en 2007

Increased mitochondrial electron transport chain activity at complex I is regulated by N-acetylcysteine in lymphocytes of patients with systemic lupus erythematosus

artículo científico publicado en 2014

Increased prevalence of transfusion-transmitted virus and cross-reactivity with immunodominant epitopes of the HRES-1/p28 endogenous retroviral autoantigen in patients with systemic lupus erythematosus

artículo científico publicado en 2005

Independence of depressed lectin-dependent cell-mediated cytotoxicity from interleukin 2 production in patients with systemic lupus erythematosus

scientific article published on 01 August 1986

Indomethacin abrogates the suppression by cyclosporin A of lectin-dependent cell-mediated cytotoxicity to HEp-2 cells

artículo científico publicado en 1986

Induction of systemic lupus erythematosus with tumor necrosis factor blockers

artículo científico publicado en 2010

Infection in systemic lupus erythematosus: friend or foe?

artículo científico publicado en 2010

Inhibition of the catalytic activity of human transaldolase by antibodies and site-directed mutagenesis

artículo científico publicado en 1996

Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus

artículo científico

Ketoconazole in vitro inhibits mitogen-induced blastogenesis, antibody-dependent cellular cytotoxicity, natural killer activity and random migration of human leukocytes

scientific article published on 01 June 1984

Lectin-dependent cell-mediated cytotoxicity and blastogenesis by large granular-enriched and depleted lymphocytes

artículo científico publicado en 1986

Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus

artículo científico publicado en 2015

Lymphoedema: a paradoxical effect of tumour necrosis factor inhibitors - case report and review of literature

artículo científico publicado en 2009

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus

artículo científico publicado en 2013

Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus

artículo científico publicado en 2014

Metabolic control of the epigenome in systemic Lupus erythematosus

artículo científico publicado en 2013

Metabolic regulation of organelle homeostasis in lupus T cells

artículo científico publicado en 2012

Metabolic switches of T-cell activation and apoptosis

artículo científico publicado en 2002

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice

artículo científico publicado en 2016

Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus

artículo científico publicado en 2004

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus

artículo científico publicado en 2002

Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity

artículo científico publicado en 2004

Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency

artículo científico publicado en 2010

Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE.

scientific article published on May 2008

Molecular ordering in HIV-induced apoptosis. Oxidative stress, activation of caspases, and cell survival are regulated by transaldolase

artículo científico publicado en 1998

Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor γ.

artículo científico publicado en 2012

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial

artículo científico publicado en 2012

Nitric oxide, mitochondrial hyperpolarization, and T cell activation

artículo científico publicado en 2007

Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells

artículo científico publicado en 2004

Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis

artículo científico publicado en 1994

Overview of signal processing by the immune system in systemic lupus erythematosus.

artículo científico publicado en 2008

Oxidative Stress and ADHD: A Meta-Analysis

artículo científico publicado en 2013

Oxidative stress and Treg depletion in lupus patients with anti-phospholipid syndrome

artículo científico publicado en 2015

Oxidative stress and endosome recycling are complementary mechanisms reorganizing the T-cell receptor signaling complex in SLE

artículo científico publicado el 30 de diciembre de 2011

Oxidative stress in the pathology and treatment of systemic lupus erythematosus

artículo científico publicado en 2013

Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase

artículo científico publicado en 2011

Pathogenic mechanisms in systemic lupus erythematosus.

artículo científico publicado en 2010

Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

artículo científico publicado en 2002

Pharmacotherapy of systemic lupus erythematosus.

artículo científico publicado en 2009

Polymerase chain reaction in clinical diagnosis

artículo científico publicado en 1990

Polymorphic genotypes of the HRES-1 human endogenous retrovirus locus correlate with systemic lupus erythematosus and autoreactivity

artículo científico publicado en 1999

Possible pathogenic nature of the recently discovered TT virus: does it play a role in autoimmune rheumatic diseases?

artículo científico publicado en 2006

Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine

artículo científico publicado en 2009

Psychiatric Symptoms in Systemic Lupus Erythematosus

scholarly article by Zsuzsa Szombathyne Meszaros et al published 1 May 2012 in The Journal of Clinical Psychiatry

Psychiatric symptoms in systemic lupus erythematosus: a systematic review

artículo científico

Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus

artículo científico publicado en 2006

Rearrangement of the T-cell receptor alpha, beta and gamma chain genes in chronic lymphocytic leukemia

artículo científico publicado en 1990

Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection

artículo científico publicado en 2006

Relationship between posttranslational modification of transaldolase and catalase deficiency in UV-sensitive repair-deficient xeroderma pigmentosum fibroblasts and SV40-transformed human cells

artículo científico publicado en 2001

Signaling abnormalities in systemic lupus erythematosus as potential drug targets

artículo científico publicado en 2006

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.

artículo científico publicado en 2018

Stimulation by thymopoietin oligopeptides of lectin-dependent cell-mediated cytotoxicity in patients with systemic lupus erythematosus

scientific article published on 01 November 1985

Stimulation of lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells by carrageenan

scientific article published on 01 November 1983

Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C.

artículo científico publicado en 2000

Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.

artículo científico publicado en 2010

T Cell Activation-Induced Mitochondrial Hyperpolarization Is Mediated by Ca2+- and Redox-Dependent Production of Nitric Oxide

artículo científico publicado el 15 de noviembre de 2003

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

artículo científico publicado en 2012

T- and B-cell abnormalities in systemic lupus erythematosus

artículo científico publicado en 2005

T-cell and B-cell signaling biomarkers and treatment targets in lupus

artículo científico publicado en 2009

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

scientific article published on 16 April 2020

The combination of nuclear and mitochondrial mutations as a risk factor for idiosyncratic toxicity

artículo científico publicado en 2006

The human T-cell leukemia virus-related endogenous sequence (HRES1) is located on chromosome 1 at q42.

artículo científico publicado en 1991

The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5

artículo científico publicado en 1997

The pathogenesis of transaldolase deficiency

artículo científico publicado en 2007

The role of nitric oxide in abnormal T cell signal transduction in systemic lupus erythematosus

artículo científico publicado en 2006

The three-dimensional structure of human transaldolase

artículo científico publicado en 2000

Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing

artículo científico publicado en 2008

Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure

artículo científico publicado en 2019

Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa

artículo científico publicado en 2006

Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine

artículo científico publicado en 2020

Tuberous sclerosis and fulminant lupus in a young woman.

artículo científico publicado en 2013

ZNF143 mediates basal and tissue-specific expression of human transaldolase

artículo científico publicado en 2003

[Effect of Litoralon therapy on the lymphocytotoxicity in patients with malignant tumors]

artículo científico publicado en 1984

[Natural and lectin-dependent cell-mediated cytotoxicity in patients with SLE and metastasizing solid tumors]

scientific article published on 01 January 1984

mTOR activation triggers proinflammatory expansion of IL-4-producing and necrosis-prone double-negative T cells, precedes flares, and serves as target for treatment in patients with systemic lupus erythematosus

artículo científico publicado en 2014

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016