Lista de obras - Achim Lass - Dominio Público Uruguay

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

artículo científico publicado en 2016

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

artículo científico publicado en 2016

A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase

artículo científico publicado en 2014

A sensitive chemiluminescence method to measure the lipoxygenase catalyzed oxygenation of complex substrates

artículo científico publicado en 1999

ABHD5 Stimulates PNPLA1-mediated Omega-O-Acylceramide Biosynthesis Essential for a Functional Skin Permeability Barrier

scientific article published on 25 October 2018

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

artículo científico publicado en 2015

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

artículo científico publicado en 2011

Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients

scientific article published on 30 October 2018

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

artículo científico publicado en 2012

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

artículo científico publicado en 2014

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

artículo científico publicado en 2015

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

scientific journal article

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

scientific article published on 23 October 2008

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

artículo científico publicado en 2015

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

artículo científico publicado en 2009

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

artículo científico publicado en 2006

Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.

artículo científico publicado en 2011

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

artículo científico publicado en 2019

Antioxidative and myocardial protective effects of L-arginine in oxygen radical-induced injury of isolated perfused rat hearts

artículo científico publicado en 2002

Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria

artículo científico publicado en 1998

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

artículo científico publicado en 2013

Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363

artículo científico publicado en 2010

Comparative transcriptomics reveals candidate carotenoid color genes in an East African cichlid fish

artículo científico publicado en 2020

Comparisons of coenzyme Q bound to mitochondrial membrane proteins among different mammalian species

artículo científico publicado en 1999

DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling

artículo científico publicado en 2015

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

artículo científico publicado en 2006

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

artículo científico publicado en 2015

Development of small-molecule inhibitors targeting adipose triglyceride lipase

artículo científico publicado en 2013

Effect of coenzyme Q(10) and alpha-tocopherol content of mitochondria on the production of superoxide anion radicals

scientific article published on 01 January 2000

Effects of coenzyme Q10 and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial alpha-tocopherol by coenzyme Q10.

artículo científico publicado en 1999

Electron transport-linked ubiquinone-dependent recycling of alpha-tocopherol inhibits autooxidation of mitochondrial membranes

artículo científico publicado en 1998

Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends.

artículo científico publicado en 2014

Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver

artículo científico publicado en 2009

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

artículo científico publicado en 2012

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

artículo científico publicado en 2015

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.

artículo científico publicado en 2011

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

artículo científico publicado en 2004

Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes

artículo científico publicado en 2014

Fate of fat: the role of adipose triglyceride lipase in lipolysis

artículo científico publicado en 2008

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling

artículo científico publicado en 2015

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

artículo científico publicado en 2014

Functional and analytical evidence for scavenging of oxygen radicals by L-arginine

artículo científico publicado en 2002

Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.

artículo científico publicado en 2013

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

artículo científico publicado en 2012

Genetically modified mouse models to study hepatic neutral lipid mobilization

artículo científico publicado en 2018

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

artículo científico publicado en 2009

Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores

artículo científico publicado en 2016

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation

scientific article published on 25 April 2019

Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

scientific journal article

Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: antioxidant actions in addition to hydroperoxide-reducing activity

scientific article published on 01 September 1996

Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress

artículo científico publicado en 2012

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores ⬇️

artículo científico publicado el 16 de noviembre de 2010

Lipolysis: pathway under construction

artículo científico publicado en 2005

Lipoxygenase treatment render low-density lipoprotein susceptible to Cu2+-catalysed oxidation

artículo científico publicado en 1996

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

artículo científico publicado en 2016

Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

artículo científico publicado en 2009

Measurement of lipolysis

artículo científico publicado en 2014

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

artículo científico publicado en 2019

Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice

artículo científico publicado en 2020

Mitochondrial coenzyme Q content and aging

artículo científico publicado en 1999

Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species

artículo científico publicado en 1997

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice

artículo científico publicado en 2017

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity

artículo científico publicado en 2015

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

artículo científico publicado en 2011

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

artículo científico publicado en 2015

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

artículo científico publicado en 2009

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

artículo científico publicado en 2016

Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite

artículo científico publicado en 2001

Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite

artículo científico publicado en 2001

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.

artículo científico publicado en 2010

Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes

artículo científico publicado en 2014

Remodeling of lipid droplets during lipolysis and growth in adipocytes

artículo científico publicado en 2012

Retinyl ester hydrolases and their roles in vitamin A homeostasis

artículo científico publicado en 2012

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

article

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

artículo científico publicado en 2016

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

artículo científico publicado en 2012

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

artículo científico publicado en 2008

The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase

artículo científico publicado en 2010

The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage

artículo científico publicado en 2013

The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis

artículo científico publicado en 2014

The lipolytic proteome of mouse adipose tissue

artículo científico publicado en 2005

The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively

artículo científico publicado en 2011

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

artículo científico publicado en 2015

Lista de obras de Achim Lass

A Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and Genetics

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase

A sensitive chemiluminescence method to measure the lipoxygenase catalyzed oxygenation of complex substrates

ABHD5 Stimulates PNPLA1-mediated Omega-O-Acylceramide Biosynthesis Essential for a Functional Skin Permeability Barrier

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

Antioxidative and myocardial protective effects of L-arginine in oxygen radical-induced injury of isolated perfused rat hearts

Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363

Comparative transcriptomics reveals candidate carotenoid color genes in an East African cichlid fish

Comparisons of coenzyme Q bound to mitochondrial membrane proteins among different mammalian species

DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

Development of small-molecule inhibitors targeting adipose triglyceride lipase

Effect of coenzyme Q(10) and alpha-tocopherol content of mitochondria on the production of superoxide anion radicals

Effects of coenzyme Q10 and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial alpha-tocopherol by coenzyme Q10.

Electron transport-linked ubiquinone-dependent recycling of alpha-tocopherol inhibits autooxidation of mitochondrial membranes

Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends.

Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver

FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease.

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes

Fate of fat: the role of adipose triglyceride lipase in lipolysis

Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

Functional and analytical evidence for scavenging of oxygen radicals by L-arginine

Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.

G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase

Genetically modified mouse models to study hepatic neutral lipid mobilization

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation

Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: antioxidant actions in addition to hydroperoxide-reducing activity

Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores ⬇️

Lipolysis: pathway under construction

Lipoxygenase treatment render low-density lipoprotein susceptible to Cu2+-catalysed oxidation

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

Measurement of lipolysis

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice

Mitochondrial coenzyme Q content and aging

Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite

Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ.

Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes

Remodeling of lipid droplets during lipolysis and growth in adipocytes

Retinyl ester hydrolases and their roles in vitamin A homeostasis

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases

The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding

The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase

The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage