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Lista de obras de Robert S Chapkin

5-Series peptido-leukotriene synthesis in mouse peritoneal macrophages: Modulation by dietary n-3 fatty acids

article

A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis.

artículo científico publicado en 2011

A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas.

artículo científico publicado en 2012

A high legume low glycemic index diet improves serum lipid profiles in men.

artículo científico publicado en 2010

A macrophage-smooth muscle cell co-culture model: Applications in the study of atherogenesis

article

A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response.

artículo científico publicado en 2012

A novel role for nutrition in the alteration of functional microdomains on the cell surface.

artículo científico publicado en 2009

A rapid RT-PCR method for detection of intact RNA in formalin-fixed paraffin-embedded tissues

artículo científico publicado en 1995

A two-stage normalization method for partially degraded mRNA microarray data.

artículo científico publicado en 2005

Aberrant crypt foci and semiparametric modeling of correlated binary data.

artículo científico publicado en 2007

Ability of 15-hydroxyeicosatrienoic acid (15-OH-20:3) to modulate macrophage arachidonic acid metabolism

artículo científico publicado en 1988

Alteration of EGFR spatiotemporal dynamics suppresses signal transduction.

artículo científico publicado en 2012

Alteration of colonic stem cell gene signatures during the regenerative response to injury

artículo científico publicado el 30 de junio de 2012

Alteration of glycerolipid and sphingolipid-derived second messenger kinetics in ras transformed 3T3 cells

artículo científico publicado en 1996

Alteration of in vitro murine peritoneal macrophage function by dietary enrichment with eicosapentaenoic and docosahexaenoic acids in menhaden fish oil.

artículo científico publicado en 1989

Analysis of epidermal growth factor receptor dimerization by BS³ cross-linking

artículo científico publicado en 2015

Anatomical site-specific response to DNA damage is related to later tumor development in the rat azoxymethane colon carcinogenesis model

article

Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.

artículo científico publicado en 2014

Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)

scientific article published on 11 September 2020

Assessing the Multivariate Relationship between the Human Infant Intestinal Exfoliated Cell Transcriptome (Exfoliome) and Microbiome in Response to Diet

artículo científico publicado en 2020

Bioactive dietary long-chain fatty acids: emerging mechanisms of action.

artículo científico publicado en 2008

Cell cycle related inhibition of mouse vascular smooth muscle cell proliferation by prostaglandin E1: relationship between prostaglandin E1 and intracellular cAMP levels

artículo científico publicado en 1996

Chain elongation of eicosapentaenoic acid in the macrophage

article

Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model

artículo científico publicado el 25 de abril de 2012

Chemoprotective epigenetic mechanisms in a colorectal cancer model: Modulation by n-3 PUFA in combination with fermentable fiber

artículo científico publicado en 2015

Chemotherapeutic Properties of n-3 Polyunsaturated Fatty Acids - Old Concepts and New Insights.

scientific article published on March 2009

Classification of diet-modulated gene signatures at the colon cancer initiation and progression stages

artículo científico publicado en 2011

Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation.

artículo científico publicado en 2014

Comparing automatic and manual image processing in FLARE assay analysis for colon carcinogenesis

artículo científico publicado en 2005

Composition of mouse peritoneal macrophage phospholipid molecular species

article

Diacylglycerol and ceramide kinetics in primary cultures of activated T-lymphocytes

artículo científico publicado en 1996

Diet and carcinogen alter luminal butyrate concentration and intracellular pH in isolated rat colonocytes

article

Dietary Fat and Fiber Modulate the Effect of Carcinogen on Colonic Protein Kinase C λ Expression in Rats , ,

artículo científico publicado el 1 de octubre de 1997

Dietary Fish Oil Promotes Colonic Apoptosis and Mitochondrial Proton Leak in Oxidatively Stressed Mice

artículo científico publicado el 13 de abril de 2011

Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice.

artículo científico publicado en 2009

Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production

artículo científico publicado en 2004

Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation.

artículo científico publicado en 2009

Dietary eicosapentaenoic acid modulates CTLA-4 expression in murine CD4+ T-cells

artículo científico publicado en 2005

Dietary fat and fiber differentially alter intracellular second messengers during tumor devolopment in rat colon

article

Dietary fat and fiber interact to uniquely modify global histone post-translational epigenetic programming in a rat colon cancer progression model

artículo científico publicado en 2018

Dietary fat and fiber modulate colonic cell proliferation in an interactive site‐specific manner

article

Dietary fiber differentially alters cellular fatty acid‐binding protein expression in exfoliated colonocytes during tumor development

article

Dietary fish oil and DHA down-regulate antigen-activated CD4+ T-cells while promoting the formation of liquid-ordered mesodomains.

artículo científico publicado en 2013

Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.

artículo científico publicado en 2011

Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3

artículo científico publicado en 2007

Dietary manipulation of macrophage phospholipid classes: selective increase of dihomogammalinolenic acid

artículo científico publicado en 1988

Dietary modulation of rat colonic cAMP-dependent protein kinase activity

article

Dietary n-3 PUFA affect TcR-mediated activation of purified murine T cells and accessory cell function in co-cultures

artículo científico publicado en 2002

Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function

artículo científico publicado en 2002

Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis

artículo científico publicado en 2012

Dietary n-3 polyunsaturated fatty acids modulate purified murine T-cell subset activation

artículo científico publicado en 2001

Dietary n-3 polyunsaturated fatty acids suppress splenic CD4(+) T cell function in interleukin (IL)-10(-/-) mice.

artículo científico publicado en 2005

Dietary polyunsaturated fatty acids modulate resistance to Mycobacterium tuberculosis in guinea pigs

artículo científico publicado en 2008

Dietary γ-Linolenic Acid Enhances Mouse Macrophage-Derived Prostaglandin E1 Which Inhibits Vascular Smooth Muscle Cell Proliferation ,

artículo científico publicado el 1 de septiembre de 1997

Dietary γ-Linolenic Acid Modulates Macrophage–Vascular Smooth Muscle Cell Interactions

article

Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.

artículo científico publicado en 2013

Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.

artículo científico publicado en 2009

Docosahexaenoic acid alters the size and distribution of cell surface microdomains

artículo científico publicado en 2007

Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation

artículo científico publicado en 2007

Effect of dietary linseed oil on tumoricidal activity and eicosanoid production in murine macrophages.

artículo científico publicado en 1994

Effect of dietary n-3 fatty acids on interleukin-2 and interleukin-2 receptor alpha expression in activated murine lymphocytes

artículo científico publicado en 1998

Effects of dietary n-3 polyunsaturated fatty acids on T-cell membrane composition and function.

artículo científico publicado en 2004

Effects of dietary n−3 and n−6 polyunsaturated fatty acids on macrophage phospholipid classes and subclasses

article

Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells

artículo científico publicado en 2014

Energy Metabolism of Rat Colonocytes Changes during the Tumorigenic Process and Is Dependent on Diet and Carcinogen

artículo científico publicado el 1 de agosto de 1998

Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach

artículo científico publicado en 2010

Fatty acid composition of macrophage phospholipids in mice fed fish or borage oil.

artículo científico publicado en 1988

Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed.

artículo científico publicado en 2015

Fish Oil Blocks Azoxymethane-Induced Rat Colon Tumorigenesis by Increasing Cell Differentiation and Apoptosis Rather Than Decreasing Cell Proliferation

artículo científico publicado el 1 de marzo de 1998

Fish Oil Enhances Targeted Apoptosis During Colon Tumor Initiation in Part by Downregulating Bcl-2

article

Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon

artículo científico publicado en 2005

GROWTH-RELATED SIGNALING IN VASCULAR SMOOTH MUSCLE CELLS OS DEREGULATED BY TCDD DURING THE G0/G1, TRANSITION

article

Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression

scientific article published on 22 October 2013

Homeostatic responses of colonic LGR5+ stem cells following acute in vivo exposure to a genotoxic carcinogen

artículo científico publicado en 2015

Host-microbe interactions in the neonatal intestine: role of human milk oligosaccharides.

artículo científico publicado en 2012

Identification of actively translated mRNA transcripts in a rat model of early-stage colon carcinogenesis.

artículo científico publicado en 2009

Imaging inflammation in mouse colon using a rapid stage-scanning confocal fluorescence microscope

artículo científico publicado en 2012

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis

artículo científico publicado el 22 de septiembre de 2011

Importance of Dietary γ-Linolenic Acid in Human Health and Nutrition

artículo científico publicado el 1 de septiembre de 1998

In vivo formation of polyphosphoinositide isomers and association with progression of murine polycystic kidney disease

article

Inability of skin enzyme preparations to biosynthesize arachidonic acid from linoleic acid

artículo científico publicado en 1984

Incorporation of a dietary omega 3 fatty acid impairs murine macrophage responses to Mycobacterium tuberculosis

artículo científico publicado en 2010

Inhibition of growth and linoleate-enhanced metastasis of a transplantable mouse mammary tumor by indomethacin

artículo científico publicado en 1988

Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing

artículo científico publicado el 20 de febrero de 2013

Insight into hypoxia tolerance in cowpea bruchid: metabolic repression and heat shock protein regulation via hypoxia-inducible factor 1.

artículo científico publicado en 2013

Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet

artículo científico publicado el 15 de marzo de 2011

Interactions of phospholipase D and cytochrome P450 protein stability

artículo científico publicado en 2004

Interactive effects of fatty acid and butyrate-induced mitochondrial Ca²⁺ loading and apoptosis in colonocytes

artículo científico publicado en 2011

Interference with Protein Kinase C-Related Signal Transduction in Vascular Smooth Muscle Cells by Benzo[a]pyrene

artículo científico publicado en 1995

Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes

artículo científico publicado en 2011

Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition

article

Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells

artículo científico publicado en 2020

Mechanisms by Which Pleiotropic Amphiphilic n-3 PUFA Reduce Colon Cancer Risk

artículo científico publicado en 2014

Mechanistic insights into the role of microRNAs in cancer: influence of nutrient crosstalk.

artículo científico publicado en 2012

Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids

artículo científico publicado el 18 de abril de 2012

Metabolism and function of skin lipids

artículo científico publicado en 1988

Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities

artículo científico publicado en 2014

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4(+) T cell metabolic activation.

artículo científico publicado en 2014

Modulation of Intracellular Second Messengers by Dietary Fat during Colonic Tumor Development

artículo científico publicado el 1 de enero de 1997

Modulation of Protein Kinase C-Related Signal Transduction by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exhibits Cell Cycle Dependence

article

Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid

artículo científico publicado el 1 de agosto de 1992

Non-invasive analysis of intestinal development in preterm and term infants using RNA-Sequencing

artículo científico publicado en 2014

Non-invasive detection of fecal protein kinase C betaII and zeta messenger RNA: putative biomarkers for colon cancer

artículo científico publicado el 1 de febrero de 1998

Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas

scientific article published on 26 May 2009

Noninvasive molecular fingerprinting of host-microbiome interactions in neonates

artículo científico publicado en 2014

Noninvasive stool-based detection of infant gastrointestinal development using gene expression profiles from exfoliated epithelial cells.

artículo científico publicado en 2010

Oncogenic ras alters sensitivity of mouse colonocytes to butyrate and fatty acid mediated growth arrest and apoptosis

artículo científico publicado en 2002

Personalized Nutrition Using Microbial Metabolite Phenotype to Stratify Participants and Non-Invasive Host Exfoliomics Reveal the Effects of Flaxseed Lignan Supplementation in a Placebo-Controlled Crossover Trial

artículo científico publicado en 2022

Pro-oxidant environment of the colon compared to the small intestine may contribute to greater cancer susceptibility.

artículo científico publicado en 2004

Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.

artículo científico publicado en 2009

Prostaglandin profile and synthetic capacity of the colon: comparison of tissue sources and subcellular fractions

artículo científico publicado en 1992

Protein kinase C isoforms in human and rat colonic mucosa

artículo científico publicado en 1994

Protein kinase C zeta isoform is critical for mitogenic signal transduction

artículo científico publicado en 1993

Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes

artículo científico publicado en 1993

Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study

article

Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis

artículo científico publicado en 2008

Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk

artículo científico publicado en 2016

Recent advances in the field of nutritional immunology.

artículo científico publicado en 2011

Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice

artículo científico publicado en 2008

Relationship among colonocyte proliferation, differentiation, and apoptosis as a function of diet and carcinogen

article

Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavones.

artículo científico publicado en 2018

Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes.

artículo científico publicado en 2007

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

artículo científico publicado en 2012

Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.

artículo científico publicado en 2011

The Induction of Proliferative Vascular Smooth Muscle Cell Phenotypes by Benzo(a)pyrene Is Characterized by Up-Regulation of Inositol Phospholipid Metabolism and c-Ha-ras Gene Expression

article

The Microbiome and Colorectal Neoplasia: Environmental Modifiers of Dysbiosis

artículo científico publicado el 1 de septiembre de 2013

Upregulation of p21Waf1/Cip1 expression in vivo by butyrate administration can be chemoprotective or chemopromotive depending on the lipid component of the diet

artículo científico publicado en 2008

Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.

artículo científico publicado en 2008

Utilization of dihomo-gamma-linolenic acid (8,11,14-eicosatrienoic acid) by murine peritoneal macrophages

artículo científico publicado en 1988

Utilization of gammalinolenic acid by mouse peritoneal macrophages

artículo científico publicado en 1991

Wheat Bran Diet Reduces Tumor Incidence in a Rat Model of Colon Cancer Independent of Effects on Distal Luminal Butyrate Concentrations ,

artículo científico publicado el 1 de noviembre de 1997

fat-1 transgene expression prevents cell culture-induced loss of membrane n-3 fatty acids in activated CD4+ T-cells

scientific article published on 31 October 2008

n-3 Fatty acids uniquely affect anti-microbial resistance and immune cell plasma membrane organization

artículo científico publicado en 2011

n-3 PUFA and membrane microdomains: a new frontier in bioactive lipid research.

artículo científico publicado en 2004

n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4⁺ T cells

artículo científico publicado en 2014

n-3 Polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by targeting plasma membrane molecular organization

artículo científico

n-3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation.

artículo científico publicado en 2012

n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formation

artículo científico publicado en 2008

n-3 polyunsaturated fatty acids--physiological relevance of dose.

artículo científico publicado en 2010

n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells

artículo científico publicado en 2013