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Lista de obras de Harald Hampel

A case of Ganser's state presenting as a dementia syndrome

artículo científico publicado en 1996

A common challenge in older adults: Classification, overlap, and therapy of depression and dementia

artículo científico publicado en 2016

A frontline defense against neurodegenerative diseases:the development of early disease detection methods

artículo científico publicado en 2019

A multicenter reproducibility study of single-voxel 1H-MRS of the medial temporal lobe.

artículo científico publicado en 2006

A new sandwich immunoassay for detection of the α-secretase cleaved, soluble amyloid-β protein precursor in cerebrospinal fluid and serum

artículo científico publicado en 2013

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

artículo científico publicado en 2016

APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease

artículo científico publicado en 2013

Advances and perspectives from genetic research: development of biological markers in Alzheimer's disease

artículo científico publicado en 2010

Advances in the development of biomarkers for Alzheimer's disease: from CSF total tau and Abeta(1-42) proteins to phosphorylated tau protein

artículo científico publicado en 2003

Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future

artículo científico publicado en 2014

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

artículo científico publicado en 2014

Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study

artículo científico publicado en 2020

Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease

artículo científico publicado en 2002

Age-related cortical grey matter reductions in non-demented Down's syndrome adults determined by MRI with voxel-based morphometry.

artículo científico publicado en 2004

Age-related networks of regional covariance in MRI gray matter: reproducible multivariate patterns in healthy aging

artículo científico publicado en 2009

Alterations in activation between mild cognitive impaired subjects during a working memory task and resting coherent network

Alterations in activation between mild cognitive impaired subjects during a working memory task and resting coherent network

Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment

artículo científico publicado en 2010

Alzheimer disease: from inherited to sporadic AD-crossing the biomarker bridge.

artículo científico publicado en 2012

Alzheimer disease: functional abnormalities in the dorsal visual pathway

artículo científico publicado en 2010

Alzheimer's Disease Diagnosis Relies on a Twofold Clinical-Biological Algorithm: Three Memory Clinic Case Reports

artículo científico publicado en 2017

Alzheimer's disease biomarker-guided diagnostic workflow using the added value of six combined cerebrospinal fluid candidates: Aβ1-42, total-tau, phosphorylated-tau, NFL, neurogranin, and YKL-40.

artículo científico publicado en 2018

Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects

artículo científico publicado en 2015

Alzheimer's disease pathophysiology in the Retina

artículo científico publicado en 2024

Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load.

artículo científico publicado en 2007

Amyloid β (Aβ) and phospho-tau (p-tau) as diagnostic biomarkers in Alzheimer's disease

artículo científico publicado en 2011

Amyloid-β and cognition in aging and Alzheimer's disease: molecular and neurophysiological mechanisms

artículo científico

Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease

artículo científico publicado en 2012

Amyloidosis and neurodegeneration result in distinct structural connectivity patterns in mild cognitive impairment.

artículo científico publicado en 2017

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies

artículo científico publicado en 2006

Anatomical MRI and DTI in the diagnosis of Alzheimer's disease: a European multicenter study

artículo científico publicado en 2012

Anticonvulsants in the treatment of aggression in the demented elderly: an update

artículo científico publicado en 2009

Antihypertensive therapy is associated with reduced rate of conversion to Alzheimer's disease in midregional proatrial natriuretic peptide stratified subjects with mild cognitive impairment

artículo científico publicado en 2011

Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease

artículo científico publicado en 2014

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study

artículo científico publicado en 2015

Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study

artículo científico publicado en 2019

Application of Systems Theory in Longitudinal Studies on the Origin and Progression of Alzheimer's Disease

artículo científico publicado en 2016

Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice

artículo científico publicado en 2018

Assessing neuronal networks: understanding Alzheimer's disease

artículo científico publicado en 2009

Assessing therapeutic efficacy in a progressive disease: a study of donepezil in Alzheimer's disease.

artículo científico publicado en 2006

Association between psychotic symptoms and cortical thickness reduction across the schizophrenia spectrum

artículo científico publicado en 2012

Association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent

artículo científico publicado en 2010

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

artículo científico publicado en 2017

Association of brain network dynamics with plasma biomarkers in subjective memory complainers

artículo científico publicado en 2019

Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers

artículo científico publicado en 2018

Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers

scientific article published on 17 August 2020

Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes

artículo científico publicado en 2011

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated cortical thickness measurements from MRI can accurately separate Alzheimer's patients from normal elderly controls

artículo científico publicado en 2006

Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease

artículo científico publicado en 2009

Automatic detection of Alzheimer's disease in multicenter DTI data

article

Automatic detection of Alzheimer's disease in multicenter diffusion tensor imaging data

article

Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors

scholarly article by Stefan J Teipel et al published 2018 in Frontiers in Neurology

Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.

artículo científico publicado en 2003

Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease

artículo científico publicado en 2009

Biological Mechanism-based Neurology and Psychiatry: a BACE1/2 and Downstream Pathway Model

artículo científico publicado en 2021

Biological and methodical challenges of blood-based proteomics in the field of neurological research

artículo científico publicado en 2012

Biological marker candidates of Alzheimer's disease in blood, plasma, and serum.

artículo científico publicado en 2009

Biological markers for early detection and pharmacological treatment of Alzheimer's disease

artículo científico publicado en 2009

Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease

artículo científico publicado en 2003

Biological markers of amyloid beta-related mechanisms in Alzheimer's disease

artículo científico publicado en 2010

Biomarker Based Diagnosis Of Very Mild Alzheimer'S Disease: A Multicenter Study

article

Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics

artículo científico publicado en 2011

Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer's Precision Medicine and Pharmacology

article published in 2019

Biomarker-based dissection of neurodegenerative diseases

scientific article published on 16 April 2011

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

scientific article published on 13 September 2019

Biomarker-guided clustering of Alzheimer's disease clinical syndromes

artículo científico publicado en 2019

Biomarkers for Alzheimer's disease therapeutic trials

artículo científico publicado en 2010

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

scientific article published on July 2010

Biomarkers for major depression and its delineation from neurodegenerative disorders

artículo científico publicado en 2011

Biomarkers in Sporadic and Familial Alzheimer's Disease

artículo científico

Biomarkers in amyloid-β immunotherapy trials in Alzheimer's disease

artículo científico publicado en 2013

Biomarkers in clinical trials for neurodegenerative diseases: Regulatory perspectives and requirements

artículo científico publicado en 2011

Biomarkers in the diagnosis of Alzheimer's disease: are we ready?

artículo científico publicado en 2006

Blood and plasma-based proteomic biomarker research in Alzheimer's disease

artículo científico

Blood-Based Biomarker Screening with Agnostic Biological Definitions for an Accurate Diagnosis Within the Dimensional Spectrum of Neurodegenerative Diseases.

artículo científico publicado en 2018

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

artículo científico publicado en 2018

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

artículo científico publicado en 2016

Blood-based biomarkers of microvascular pathology in Alzheimer's disease

artículo científico publicado en 2009

Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio.

artículo científico publicado en 2009

Blood-based protein biomarkers for diagnosis and classification of neurodegenerative diseases: current progress and clinical potential

artículo científico publicado en 2011

Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease

artículo científico publicado en 2011

Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

scientific article published on 01 October 2019

CSF Aβ1-42 combined with neuroimaging biomarkers in the early detection, diagnosis and prediction of Alzheimer's disease

artículo científico publicado en 2013

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

artículo científico publicado en 2009

CSF biomarkers for the differential diagnosis of Alzheimer's disease: A large-scale international multicenter study.

artículo científico publicado en 2015

CSF markers for incipient Alzheimer's disease

artículo científico publicado en 2003

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease

artículo científico publicado en 2006

CSF tau and β-amyloid as biomarkers for mild cognitive impairment.

artículo científico publicado en 2004

Caffeic acid phenethyl ester blocks free radical generation and 6-hydroxydopamine-induced neurotoxicity

artículo científico publicado en 2006

Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury

artículo científico publicado en 2004

Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study

artículo científico publicado en 2017

Cerebrospinal Fluid Stanniocalcin-1 as a Biomarker for Alzheimer's Disease and Other Neurodegenerative Disorders

artículo científico publicado en 2016

Cerebrospinal fluid analysis in Alzheimer's disease: technical issues and future developments

artículo científico

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

artículo científico publicado en 2017

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

artículo científico publicado en 2010

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

artículo científico publicado en 2017

Classifying brain states and determining the discriminating activation patterns: Support Vector Machine on functional MRI data

artículo científico publicado en 2005

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease

artículo científico publicado en 2014

Cognitive and behavioural effects of physical exercise in psychiatric patients

artículo científico publicado en 2011

Cognitive intervention in Alzheimer disease.

artículo científico publicado en 2010

Combination of Structural MRI and FDG-PET of the Brain Improves Diagnostic Accuracy in Newly Manifested Cognitive Impairment in Geriatric Inpatients

artículo científico publicado en 2016

Combining DTI and MRI for the Automated Detection of Alzheimer’s Disease Using a Large European Multicenter Dataset

article

Combining morphometric measurements of the basal forebrain cholinergic system and cortical thickness for better diagnostic accuracy

Combining morphometric measurements of the basal forebrain cholinerigc system and the cortical thickness for better diagnostic accuracy

Commentary: Development of the Blood-Based Alzheimer's Disease Liquid Biopsy

artículo científico publicado en 2019

Common capacity-limited neural mechanisms of selective attention and spatial working memory encoding

artículo científico publicado en 2011

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

artículo científico publicado en 2011

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

artículo científico publicado en 2021

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

artículo científico publicado en 2016

Comprehensive dissection of the medial temporal lobe in AD: measurement of hippocampus, amygdala, entorhinal, perirhinal and parahippocampal cortices using MRI.

artículo científico publicado en 2006

Core candidate neurochemical and imaging biomarkers of Alzheimer's disease

artículo científico publicado en 2007

Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline.

artículo científico publicado en 2018

Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease

artículo científico publicado en 2005

Current insights into the pathophysiology of Alzheimer's disease: selecting targets for early therapeutic intervention

artículo científico

Current state of Alzheimer's fluid biomarkers

scholarly article by José Luis Molinuevo et al published 1 December 2018 in Acta Neuropathologica

DOES BRAIN AMYLOID DEPOSITION IMPACT EVERYDAY FUNCTIONING IN SUBJECTS WITH COGNITIVE COMPLAINTS? RESULTS FROM THE INSIGHT COHORT

DSM-5 reviewed from different angles: goal attainment, rationality, use of evidence, consequences--part 1: general aspects and paradigmatic discussion of depressive disorders

artículo científico

DSM-5 reviewed from different angles: goal attainment, rationality, use of evidence, consequences—part 2: bipolar disorders, schizophrenia spectrum disorders, anxiety disorders, obsessive-compulsive disorders, trauma- and stressor-related disorders,

artículo científico publicado en 2014

Decreased activation along the dorsal visual pathway after a 3-month treatment with galantamine in mild Alzheimer disease: a functional magnetic resonance imaging study

artículo científico publicado en 2009

Decreased serum amyloid beta(1-42) autoantibody levels in Alzheimer's disease, determined by a newly developed immuno-precipitation assay with radiolabeled amyloid beta(1-42) peptide.

artículo científico publicado en 2005

Dementia: The rising global tide of cognitive impairment

artículo científico publicado en 2016

Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force

artículo científico publicado en 2013

Development of Alzheimer-disease neuroimaging-biomarkers using mouse models with amyloid-precursor protein-transgene expression.

artículo científico publicado en 2011

Development of biomarkers to chart all Alzheimer's disease stages: the royal road to cutting the therapeutic Gordian Knot

artículo científico

Diagnostic accuracy of CSF neurofilament light chain protein in the biomarker-guided classification system for Alzheimer's disease

artículo científico publicado en 2017

Diagnostic function of the neuroinflammatory biomarker YKL-40 in Alzheimer's disease and other neurodegenerative diseases

artículo científico publicado en 2017

Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease

artículo científico publicado en 2010

Diagnostic usefulness of cognitive auditory event-related p300 subcomponents in patients with Alzheimers disease?

artículo científico publicado en 2008

Diagnostic utility of novel MRI-based biomarkers for Alzheimer's disease: diffusion tensor imaging and deformation-based morphometry

artículo científico publicado en 2010

Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study

artículo científico publicado en 2009

Different effects of mirtazapine and venlafaxine on brain activation: an open randomized controlled fMRI study

artículo científico publicado en 2010

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

artículo científico publicado en 2019

Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.

artículo científico publicado en 2002

Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231.

artículo científico publicado en 2003

Diffusion tensor imaging to determine effects of antidementive treatment on cerebral structural connectivity in Alzheimer's disease

artículo científico publicado en 2013

Discovery and development of integrative biological markers for schizophrenia.

artículo científico publicado en 2011

Disrupted white matter structural networks in healthy older adult APOE ε4 carriers - An international multicenter DTI study

artículo científico publicado en 2017

Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease

artículo científico publicado en 2006

Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

artículo científico publicado en 2010

Do instrumental activities of daily living predict dementia at 1- and 2-year follow-up? Findings from the Development of Screening guidelines and diagnostic Criteria for Predementia Alzheimer's disease study

artículo científico publicado en 2011

Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease

artículo científico publicado en 2015

Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network

artículo científico publicado en 2009

Early risk assessment for Alzheimer's disease

artículo científico publicado en 2009

Effects of a 6-month cognitive intervention on brain metabolism in patients with amnestic MCI and mild Alzheimer's disease

artículo científico publicado en 2011

Effects of a 6-month cognitive intervention program on brain metabolism in amnestic mild cognitive impairment and mild Alzheimer's disease

artículo científico publicado en 2011

Effects of a newly developed cognitive intervention in amnestic mild cognitive impairment and mild Alzheimer's disease: a pilot study

artículo científico publicado en 2011

Effects of donepezil on cortical metabolic response to activation during (18)FDG-PET in Alzheimer's disease: a double-blind cross-over trial

artículo científico publicado en 2006

Effects of rivastigmine on visual attention in subjects with amnestic mild cognitive impairment: A serial functional MRI activation pilot-study

artículo científico publicado en 2016

Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

artículo científico publicado en 2011

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Ethical considerations of biomarker use in neurodegenerative diseases--a case study of Alzheimer's disease

artículo científico publicado en 2011

Evaluation of amyloid status in a cohort of elderly individuals with memory complaints: validation of the method of quantification and determination of positivity thresholds

artículo científico publicado en 2017

Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline

artículo científico publicado en 2015

Evolving Relevance of Neuroproteomics in Alzheimer's Disease

artículo científico publicado en 2017

Excess of rare coding variants in PLD3 in late- but not early-onset Alzheimer's disease

artículo científico publicado en 2015

Expression of T cell receptor gamma delta antigens in human brain tissue

scientific article published on 01 March 1995

FDG-PET mapping the brain substrates of visuo-constructive processing in Alzheimer's disease

artículo científico publicado en 2009

Fiber connections between the cerebral cortex and the corpus callosum in Alzheimer's disease: a diffusion tensor imaging and voxel-based morphometry study

artículo científico publicado en 2006

Fibrin degradation products in post mortem brain tissue of schizophrenics: a possible marker for underlying inflammatory processes

scientific article published on 01 May 1996

Focal decline of cortical thickness in Alzheimer's disease identified by computational neuroanatomy.

artículo científico publicado en 2004

Fractional anisotropy changes in Alzheimer's disease depend on the underlying fiber tract architecture: a multiparametric DTI study using joint independent component analysis.

artículo científico publicado en 2014

Free and Cued Selective Reminding Test - accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large-scale biomarker-characterized monocenter cohort study (ClinAD).

artículo científico publicado en 2017

Frequency Variation of a Pattern-Flash Visual Stimulus during PET Differentially Activates Brain from Striate through Frontal Cortex

artículo científico publicado en 1997

Frontal diaschisis in a German case of fatal familial insomnia

artículo científico publicado en 2006

Fully Automated Atlas-Based Hippocampus Volumetry for Clinical Routine: Validation in Subjects with Mild Cognitive Impairment from the ADNI Cohort

artículo científico publicado en 2015

Fully Automatic MRI-Based Hippocampus Volumetry Using FSL-FIRST: Intra-Scanner Test-Retest Stability, Inter-Field Strength Variability, and Performance as Enrichment Biomarker for Clinical Trials Using Prodromal Target Populations at Risk for Alzhei

artículo científico publicado en 2017

Fully automated atlas-based hippocampal volumetry for detection of Alzheimer's disease in a memory clinic setting

artículo científico publicado en 2015

Functional abnormalities of the visual processing system in subjects with mild cognitive impairment: an fMRI study

artículo científico publicado en 2008

Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression

artículo científico publicado en 2010

Functional magnetic resonance imaging as a dynamic candidate biomarker for Alzheimer's disease

artículo científico publicado en 2011

Functional representation of olfactory impairment in early Alzheimer's disease

artículo científico publicado en 2010

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

artículo científico publicado en 2014

Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease.

artículo científico publicado en 2005

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

artículo científico publicado en 2010

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease

artículo científico publicado en 2014

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

artículo científico publicado en 2009

Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults.

artículo científico publicado en 2018

Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality

artículo científico publicado en 2012

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

artículo científico publicado en 2015

Have we learnt all we need to know from genetic studies - is genetics over in Alzheimer's disease?

artículo científico publicado en 2013

High-resolution peptide mapping of cerebrospinal fluid: a novel concept for diagnosis and research in central nervous system diseases

artículo científico publicado en 2002

Human anti-beta-amyloid antibodies block beta-amyloid fibril formation and prevent beta-amyloid-induced neurotoxicity

artículo científico publicado en 2003

Human anti-prion antibodies block prion peptide fibril formation and neurotoxicity

artículo científico publicado en 2012

Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease.

artículo científico publicado en 2002

IFATS collection: The conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats

artículo científico publicado en 2009

Identification of novel biomarker candidates by differential peptidomics analysis of cerebrospinal fluid in Alzheimer's disease

artículo científico publicado en 2005

Imaging epigenetics in Alzheimer's disease

artículo científico publicado en 2013

Immunotherapy for Alzheimer's disease

scientific article published on 01 April 2003

Impact of employment status and work-related factors on risk of completed suicide. A case-control psychological autopsy study

artículo científico publicado en 2011

Implementation of subjective cognitive decline criteria in research studies

artículo científico publicado en 2016

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

artículo científico publicado en 2017

Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls

artículo científico publicado en 2012

Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2008

Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.

artículo científico publicado en 2011

Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment

artículo científico publicado en 2017

Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment

artículo científico publicado en 2005

Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease

artículo científico publicado en 2014

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro

artículo científico publicado en 2001

Injury markers predict time to dementia in subjects with MCI and amyloid pathology

artículo científico publicado en 2012

Interhemispheric hypoconnectivity in schizophrenia: fiber integrity and volume differences of the corpus callosum in patients and unaffected relatives

artículo científico publicado en 2011

Interleukin-6 is not altered in cerebrospinal fluid of first-degree relatives and patients with Alzheimer's disease ⬇️

artículo científico publicado el 13 de junio de 1997

Interleukin-6-174 G/C promoter gene polymorphism C allele reduces Alzheimer's disease risk.

artículo científico publicado en 2003

International quality control survey of neurochemical dementia diagnostics.

artículo científico publicado en 2006

Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment

artículo científico

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment

artículo científico publicado en 2007

Levels of total tau and tau protein phosphorylated at threonine 181 in patients with incipient and manifest Alzheimer's disease

artículo científico publicado en 2003

Lithium as a Treatment for Alzheimer's Disease: A Systematic Review and Meta-Analysis

artículo científico

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

scientific article published on 01 January 2019

Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study.

artículo científico

Long-term cost-effectiveness of donepezil for the treatment of Alzheimer's disease.

artículo científico publicado en 2007

Long-term observation of a multicomponent cognitive intervention in mild cognitive impairment

artículo científico

Longitudinal Changes in Fiber Tract Integrity in Healthy Aging and Mild Cognitive Impairment: A DTI Follow-Up Study

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

artículo científico publicado en 2015

Magnetic resonance imaging-based hippocampus volume for prediction of dementia in mild cognitive impairment: Why does the measurement method matter so little?

artículo científico publicado en 2018

Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients

artículo científico publicado en 2003

Measurement of basal forebrain atrophy in Alzheimer's disease using MRI.

artículo científico publicado en 2005

Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study

artículo científico publicado en 2004

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

artículo científico publicado en 2013

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment

artículo científico publicado en 2014

Metabolite profiling of Alzheimer's disease cerebrospinal fluid

artículo científico publicado en 2012

MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints

artículo científico publicado en 2021

Midregional Proenkephalin A and N-terminal Protachykinin A are decreased in the cerebrospinal fluid of patients with dementia disorders and acute neuroinflammation.

artículo científico publicado en 2010

Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study

artículo científico publicado en 2007

Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease.

artículo científico publicado en 2013

Multicenter stability of diffusion tensor imaging measures: a European clinical and physical phantom study

artículo científico publicado en 2011

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease

artículo científico publicado en 2010

Multidimensional biomarker-based diagnosis of early Alzheimer's disease

scholarly article by Michael Ewers et al published July 2009 in Alzheimer's and Dementia

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.

artículo científico publicado en 2007

Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment.

artículo científico publicado en 2007

Multivariate network analysis of fiber tract integrity in Alzheimer's disease

artículo científico publicado en 2006

Neural adaptation to thin and fat bodies in the fusiform body area and middle occipital gyrus: an fMRI adaptation study

artículo científico publicado en 2012

Neuroanatomy of Down syndrome in vivo: a model of preclinical Alzheimer's disease

artículo científico publicado en 2006

Neurodegenerative disease biomarkers: guideposts for disease prevention through early diagnosis and intervention

artículo científico publicado en 2011

Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia

artículo científico publicado en 2011

No correlation between CSF tau protein phosphorylated at threonine 181 with neocortical neurofibrillary pathology in Alzheimer's disease

artículo científico publicado en 2007

Non-Pharmacologic Interventions for Older Adults with Subjective Cognitive Decline: Systematic Review, Meta-Analysis, and Preliminary Recommendations

artículo científico publicado en 2017

Novel MRI techniques in the assessment of dementia

artículo científico publicado en 2008

Optimal management of Alzheimer's disease patients: Clinical guidelines and family advice

artículo científico publicado en 2010

PET and the effects of aging and neurodegeneration on brain function: basic principles

artículo científico publicado en 1998

Patterns of autobiographical memory in bipolar disorder examined by psychometric and functional neuroimaging methods

artículo científico publicado en 2012

Performance of Hippocampus Volumetry with FSL-FIRST for Prediction of Alzheimer's Disease Dementia in at Risk Subjects with Amnestic Mild Cognitive Impairment

artículo científico publicado en 2016

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020.

artículo científico publicado en 2013

Perspectives for multimodal neurochemical and imaging biomarkers in Alzheimer's disease

artículo científico

Perspectives of worldwide translational biomarker research in neurodegenerative diseases

artículo científico publicado en 2011

Pharmacological treatment of Alzheimer's dementia: state of the art and current dilemmas

artículo científico publicado en 2008

Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease

artículo científico publicado en 2019

Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease

artículo científico publicado en 2019

Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease. Results of a pilot study.

artículo científico publicado en 2003

Precision medicine and drug development in Alzheimer's disease: the importance of sexual dimorphism and patient stratification

scientific article published on 12 June 2018

Preclinical Alzheimer's disease: A systematic review of the cohorts underlying the concept

artículo científico publicado en 2017

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria.

artículo científico publicado en 2016

Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations

artículo científico publicado en 2017

Predicting prodromal Alzheimer's disease in people with mild cognitive impairment using multicenter diffusion-tensor imaging data and machine learning algorithms

article

Predicting progression from cognitive impairment to Alzheimer's disease with the Disease State Index

artículo científico publicado en 2015

Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers

artículo científico publicado en 2017

Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.

artículo científico publicado en 2013

Prediction of Alzheimer's Disease Dementia: Data from the GuidAge Prevention Trial

artículo científico publicado en 2015

Prediction of Alzheimer's disease using midregional proadrenomedullin and midregional proatrial natriuretic peptide: a retrospective analysis of 134 patients with mild cognitive impairment

artículo científico publicado en 2010

Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance

artículo científico publicado en 2010

Predictors of cognitive decline and treatment response in a clinical trial on suspected prodromal Alzheimer's disease

artículo científico

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

artículo científico publicado en 2015

Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study.

artículo científico publicado en 2009

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

artículo científico publicado en 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

artículo científico publicado en 2018

Prevention trials in Alzheimer's disease: an EU-US task force report.

artículo científico publicado en 2011

Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.

artículo científico publicado en 2007

Progression of corpus callosum atrophy in Alzheimer disease

artículo científico publicado en 2002

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Recent developments of functional magnetic resonance imaging research for drug development in Alzheimer's disease

artículo científico publicado en 2011

Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

artículo científico publicado en 2012

Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer's disease

artículo científico publicado en 2017

Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study

artículo científico publicado en 2012

Regional network of magnetic resonance imaging gray matter volume in healthy aging

artículo científico publicado en 2006

Regional networks underlying interhemispheric connectivity: an EEG and DTI study in healthy ageing and amnestic mild cognitive impairment

artículo científico publicado en 2009

Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration

artículo científico publicado en 2003

Relation between responses to repetitive transcranial magnetic stimulation and partial sleep deprivation in major depression

artículo científico publicado en 2002

Relation of corpus callosum and hippocampal size to age in nondemented adults with Down's syndrome

artículo científico publicado en 2003

Relevance of magnetic resonance imaging for early detection and diagnosis of Alzheimer disease

artículo científico publicado en 2013

Reliable manual segmentation of the frontal, parietal, temporal, and occipital lobes on magnetic resonance images of healthy subjects

artículo científico publicado en 2005

Repetitive transcranial magnetic stimulation (rTMS) in major depression: relation between efficacy and stimulation intensity

artículo científico publicado en 2002

Revised criteria for Alzheimer's disease: what are the lessons for clinicians?

artículo científico publicado en 2011

Revising the definition of Alzheimer's disease: a new lexicon.

artículo científico publicado en 2010

Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research

artículo científico publicado en 2017

Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology.

artículo científico publicado en 2018

Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data

artículo científico publicado en 2013

Severe hirsutism associated with psychopharmacological treatment in major depression

scientific article published on 01 January 2001

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

artículo científico publicado en 2018

Sexual dimorphism in healthy aging and mild cognitive impairment: a DTI study

artículo científico publicado en 2012

Single-domain amnestic mild cognitive impairment identified by cluster analysis predicts Alzheimer's disease in the european prospective DESCRIPA study

artículo científico publicado en 2013

Stage-dependent agreement between cerebrospinal fluid proteins and FDG-PET findings in Alzheimer's disease.

artículo científico publicado en 2012

Staging Alzheimer's disease progression with multimodality neuroimaging

artículo científico publicado en 2011

Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease

artículo científico publicado en 2011

Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia

artículo científico publicado en 2018

Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.

artículo científico publicado en 2015

Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study

artículo científico publicado en 2014

Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer's disease

artículo científico publicado en 2016

Systems Biology Methods for Alzheimer's Disease Research Toward Molecular Signatures, Subtypes, and Stages and Precision Medicine: Application in Cohort Studies and Trials.

artículo científico publicado en 2018

Targets of antidementive therapy: drugs with a specific pharmacological mechanism of action

artículo científico publicado en 2004

Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification

artículo científico publicado en 2007

Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI.

artículo científico publicado en 2012

The Alzheimer Precision Medicine Initiative

artículo científico publicado en 2019

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

artículo científico publicado en 2011

The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment

artículo científico publicado en 2016

The European diffusion tensor imaging study in dementia (EDSD): Physical phantom study and multimodal clinical study on the diagnosis of Alzheimer's disease

scholarly article by Stefan J Teipel et al published July 2012 in Alzheimer's and Dementia

The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment

artículo científico publicado en 2015

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

scholarly article by Daniela C. Glatz et al published February 2006 in Journal of Neurochemistry

The association between APOE ε4 and Alzheimer-type dementia among memory clinic patients is confined to those with a higher education. The DESCRIPA Study

artículo científico publicado en 2013

The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?

artículo científico publicado en 2014

The cholinergic system in mild cognitive impairment and Alzheimer's disease: an in vivo MRI and DTI study

artículo científico publicado en 2010

The cholinergic system in the pathophysiology and treatment of Alzheimer's disease

scholarly article by Harald Hampel et al published 1 July 2018 in Brain

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

artículo científico publicado en 2017

The future of Alzheimer's disease: the next 10 years

artículo científico publicado en 2011

The future of blood-based biomarkers for Alzheimer's disease

artículo científico publicado en 2013

The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster

artículo científico publicado en 2016

The neuroinflammatory biomarker YKL-40 for neurodegenerative diseases: advances in development

artículo científico publicado en 2019

The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases

scientific article published on 27 February 2020

The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium

artículo científico publicado en 2008

The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia

artículo científico publicado en 2010

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

artículo científico publicado en 2015

The role of genetics for biomarker development in neurodegeneration

artículo científico publicado en 2011

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

artículo científico publicado en 2012

The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology

artículo científico publicado en 2003

The β-Secretase BACE1 in Alzheimer's Disease

artículo científico publicado en 2020

The ε4 genotype of apolipoprotein E and white matter integrity in Alzheimer's disease

artículo científico publicado en 2013

Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer's disease

artículo científico publicado en 2019

Total and phosphorylated tau protein as biological markers of Alzheimer's disease

artículo científico publicado en 2009

Total and phosphorylated tau proteins: evaluation as core biomarker candidates in frontotemporal dementia

artículo científico publicado en 2004

Treatment options for tauopathies.

artículo científico publicado en 2012

Treatment outcomes and resource use of patients with neurogenic detrusor overactivity receiving botulinum toxin A (BOTOX) therapy in Germany.

artículo científico publicado en 2009

Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease

artículo científico publicado en 2003

Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.

artículo científico publicado en 2004

Two-level diagnostic classification using cerebrospinal fluid YKL-40 in Alzheimer's disease.

artículo científico publicado en 2017

Use of biomarkers and imaging to assess pathophysiology, mechanisms of action and target engagement.

artículo científico publicado en 2013

Using diffusion tensor imaging and mixed-effects models to investigate primary and secondary white matter degeneration in Alzheimer's disease and mild cognitive impairment

artículo científico publicado en 2011

Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment

artículo científico publicado en 2012

Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease

artículo científico publicado en 2012

Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI).

artículo científico publicado en 2009

Value of event-related P300 subcomponents in the clinical diagnosis of mild cognitive impairment and Alzheimer's Disease.

artículo científico publicado en 2002

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

artículo científico publicado en 2013

White matter damage in Alzheimer disease and mild cognitive impairment: assessment with diffusion-tensor MR imaging and parallel imaging techniques

artículo científico publicado en 2007

White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines

artículo científico publicado en 2012

White matter microstructure in relation to education in aging and Alzheimer's disease

artículo científico publicado en 2009

White matter microstructure underlying default mode network connectivity in the human brain

artículo científico publicado en 2009

β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification

artículo científico publicado en 2020

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