Lista de obras - Matthew R Groves - Dominio Público Uruguay

A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables

artículo científico publicado en 2017

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

artículo científico publicado en 2019

A unique Oct4 interface is crucial for reprogramming to pluripotency

artículo científico publicado en 2013

Acoustic Droplet Ejection Enabled Automated Reaction Scouting

artículo científico publicado en 2019

Artificial Macrocycles as IL-17A/IL-17RA Antagonists

artículo científico publicado en 2017

Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum.

artículo científico

Benchmark of Generic Shapes for Macrocycles

artículo científico publicado en 2020

Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts

artículo científico publicado en 2007

Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates

artículo científico publicado en 2008

Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum.

artículo científico publicado en 2012

Crystallization and preliminary characterization of a novel haem-binding protein of Streptomyces reticuli.

artículo científico

Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains

artículo científico publicado en 2004

Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum

artículo científico publicado en 2012

Definition of domain boundaries and crystallization of the SMN Tudor domain

artículo científico publicado en 2003

Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases

artículo científico publicado en 2011

Elucidation of haem-binding sites in the actinobacterial protein HbpS.

artículo científico publicado en 2013

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

artículo científico publicado en 2023

Fatty Acid- and Retinoid-binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo

artículo científico publicado en 2009

High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues

artículo científico publicado en 2003

Internal structure of an intact Convallaria majalis pollen grain observed with X-ray Fresnel coherent diffractive imaging

artículo científico publicado en 2012

Iron Binding at Specific Sites within the Octameric HbpS Protects Streptomycetes from Iron-Mediated Oxidative Stress

artículo científico publicado en 2013

Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum

artículo científico publicado en 2019

Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering

artículo científico publicado en 2008

Mobility of the conserved glycine 155 is required for formation of the active plasmodial Pdx1 dodecamer.

artículo científico publicado en 2009

Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2

scientific article published on 12 March 2020

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

artículo científico publicado en 2020

Novel redox-sensing modules: accessory protein- and nucleic acid-mediated signaling

artículo científico

Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide

artículo científico publicado en 2007

Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro

artículo científico publicado en 2018

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

scientific article published on 28 February 2019

Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements

artículo científico publicado el 1 de enero de 1998

Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum.

artículo científico publicado en 2010

Quantitive evaluation of macromolecular crystallization experiments using 1,8-ANS fluorescence

artículo científico publicado en 2010

ROS-Mediated Signalling in Bacteria: Zinc-Containing Cys-X-X-Cys Redox Centres and Iron-Based Oxidative Stress

artículo científico

Rapid approach to complex boronic acids

scientific article published on 05 July 2019

Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum

artículo científico publicado en 2011

Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism

artículo científico publicado en 2004

Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes ⬇️

artículo científico publicado el 1 de septiembre de 1998

Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.

artículo científico publicado en 2017

The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α-adrenoceptor

scientific article published in Scientific Reports

The assembly of the plasmodial PLP synthase complex follows a defined course

artículo científico publicado en 2008

The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels

artículo científico publicado en 2009

Theory and applications of differential scanning fluorimetry in early-stage drug discovery

artículo científico publicado en 2020

Lista de obras de Matthew R Groves

A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

A unique Oct4 interface is crucial for reprogramming to pluripotency

Acoustic Droplet Ejection Enabled Automated Reaction Scouting

Artificial Macrocycles as IL-17A/IL-17RA Antagonists

Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum.

Benchmark of Generic Shapes for Macrocycles

Canonical signal recognition particle components can be bypassed for posttranslational protein targeting in chloroplasts

Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates

Crystallization and preliminary X-ray diffraction of malate dehydrogenase from Plasmodium falciparum.

Crystallization and preliminary characterization of a novel haem-binding protein of Streptomyces reticuli.

Crystallization of a Golgi-associated PR-1-related protein (GAPR-1) that localizes to lipid-enriched microdomains

Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum

Definition of domain boundaries and crystallization of the SMN Tudor domain

Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases

Elucidation of haem-binding sites in the actinobacterial protein HbpS.

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

Fatty Acid- and Retinoid-binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo

High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues

Internal structure of an intact Convallaria majalis pollen grain observed with X-ray Fresnel coherent diffractive imaging

Iron Binding at Specific Sites within the Octameric HbpS Protects Streptomycetes from Iron-Mediated Oxidative Stress

Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum

Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering

Mobility of the conserved glycine 155 is required for formation of the active plasmodial Pdx1 dodecamer.

Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

Novel redox-sensing modules: accessory protein- and nucleic acid-mediated signaling

Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide

Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro

Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum

Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements

Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum.

Quantitive evaluation of macromolecular crystallization experiments using 1,8-ANS fluorescence

ROS-Mediated Signalling in Bacteria: Zinc-Containing Cys-X-X-Cys Redox Centres and Iron-Based Oxidative Stress

Rapid approach to complex boronic acids

Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum

Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism

Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes ⬇️

Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.

The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α-adrenoceptor

The assembly of the plasmodial PLP synthase complex follows a defined course

The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels

Theory and applications of differential scanning fluorimetry in early-stage drug discovery