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Lista de obras de Massimiliano Mazzone

"Active" cancer immunotherapy by anti-Met antibody gene transfer

artículo científico publicado en 2008

A lifeline for suffocating tissues

artículo científico publicado en 2008

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

artículo científico publicado en 2023

Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity

artículo científico publicado en 2006

Altering the intratumoral localization of macrophages to inhibit cancer progression

artículo científico publicado en 2014

An HGF-MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity.

artículo científico publicado en 2002

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 January 2020

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

artículo científico publicado en 2007

Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation

artículo científico publicado en 2010

Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?

artículo científico publicado en 2011

B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complementary Approach To Kill Pathological Vessels?

scientific article published on 12 June 2020

Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells.

artículo científico publicado en 2016

Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A

artículo científico publicado en 2014

Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding

scientific article published in 2023

Building in resistance to endothelial cell death

artículo científico publicado en 2007

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

scientific article published in Nature Communications

Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia.

artículo científico publicado en 2016

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

artículo científico publicado en 2008

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

artículo científico publicado en 2017

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

artículo científico publicado en 2014

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis

artículo científico publicado en 2016

Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival

artículo científico publicado en 2015

Functional MMP-10 is required for efficient tissue repair after experimental hind limb ischemia

artículo científico publicado en 2014

Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity

article

Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization

artículo científico publicado en 2012

Genetic targeting of the kinase activity of the Met receptor in cancer cells

artículo científico publicado en 2007

Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages

scientific article published on 04 September 2020

Growing tumor vessels: more than one way to skin a cat - implications for angiogenesis targeted cancer therapies.

artículo científico publicado en 2011

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

artículo científico publicado en 2011

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

artículo científico publicado en 2009

Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes

artículo científico publicado en 2014

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

artículo científico publicado en 2003

Hypoxia-induced miR-210 modulates the inflammatory response and fibrosis upon acute ischemia

artículo científico publicado en 2021

Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling

artículo científico publicado en 2019

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

artículo científico publicado en 2015

Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery

scientific article published on 06 July 2010

Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.

artículo científico publicado en 2013

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

artículo científico publicado en 2013

Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function

artículo científico publicado en 2021

Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis

artículo científico publicado en 2017

Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.

artículo científico publicado en 2012

Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

artículo científico publicado en 2009

MET is required for the recruitment of anti-tumoural neutrophils

artículo científico publicado en 2015

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

artículo científico publicado en 2016

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

artículo científico publicado en 2016

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

artículo científico publicado en 2011

Macrophage-derived glutamine boosts satellite cells and muscle regeneration

artículo científico publicado en 2020

Metron factor-1 prevents liver injury without promoting tumor growth and metastasis

artículo científico publicado en 2008

Novel alternatives for anti-angiogenetic therapy and therapeutic angiogenesis.

scientific article published on January 2010

Overcoming resistance to antiangiogenic therapies

artículo científico

PHD1 regulates p53-mediated colorectal cancer chemoresistance.

artículo científico publicado en 2015

PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner

artículo científico publicado en 2017

PHD2 regulates arteriogenic macrophages through TIE2 signalling

artículo científico publicado en 2013

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

artículo científico publicado en 2015

Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma.

artículo científico publicado en 2016

Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

artículo científico publicado en 2017

Regulation of angiogenesis by oxygen and metabolism.

artículo científico publicado en 2009

Renal CD133(+)/CD73(+) progenitors produce erythropoietin under hypoxia and prolyl hydroxylase inhibition

artículo científico publicado en 2013

Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism

artículo científico publicado en 2017

Role and therapeutic potential of VEGF in the nervous system

scientific article published on April 2009

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.

artículo científico publicado en 2010

Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice

artículo científico publicado en 2010

Sema3E?Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice.

artículo científico publicado en 2011

Sema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice.

artículo científico publicado en 2013

Semaphorin Signals on the Road of Endothelial Tip Cells ⬇️

artículo científico publicado el 16 de agosto de 2011

Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

artículo científico publicado en 2015

Sixty shades of oxygen-an attractive opportunity for cancer immunotherapy

artículo científico publicado en 2015

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation

artículo científico publicado en 2015

Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

artículo científico publicado en 2011

Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

artículo científico publicado en 2004

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

artículo científico publicado en 2015

The Fragile X Protein binds mRNAs involved in cancer progression and modulates metastasis formation

artículo científico publicado en 2014

The Met pathway: master switch and drug target in cancer progression

artículo científico publicado en 2006

The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.

artículo científico publicado en 2014

The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation

artículo científico publicado en 2013

The impact of hypoxia on tumor-associated macrophages

artículo científico publicado en 2016

The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo

artículo científico publicado en 2007

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

artículo científico publicado en 2008

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.

artículo científico publicado en 2016

The “cord of life” serving antiangiogenic therapy ⬇️

artículo científico publicado el 23 de mayo de 2013

Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

artículo científico publicado en 2013

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.

artículo científico publicado en 2017

Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment.

artículo científico publicado en 2013

Tumor-associated macrophages: a short compendium

artículo científico publicado en 2019

Tumour growth inhibition and anti‐metastatic activity of a mutated furin‐resistant Semaphorin 3E isoform ⬇️

artículo científico publicado el 13 de enero de 2012

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

artículo científico publicado en 2016

Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer

artículo científico publicado en 2015

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

artículo científico publicado en 2012

Vessel Normalization in the Spot-LIGHT of Cancer Treatment

scientific article published on 07 January 2016

miR-511-3p modulates genetic programs of tumor-associated macrophages

scientific journal article

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